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Tag Content
UUCD2 ID IUUC-Pab-097696
UUCD1 version UUC-PoA-00189
Ensembl Protein ID ENSPPYP00000005415.2
UniProt Accession H2NI01; H2NI01_PONAB
Genbank Protein ID ENSPPYP00000005415
Protein Name Uncharacterized protein
Genbank Nucleotide ID ABGA01237202
Gene Name MDM2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000004754.2 ENSPPYT00000005626.2 ENSPPYP00000005415.2
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 98.79 0.00e+00 862.00 IUUC-Hsa-046376
E3 activity/RING/RING 79.84 0.00e+00 651.00 IUUC-Mmu-063207
E3 activity/RING/RING 83.06 0.00e+00 681.00 IUUC-Rno-105641
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Pongo abelii
Protein Sequence
(Fasta)
MVRSRQMCNT NMSVPTDGAV TTSQIPASEQ ETLVRPKPLL LKLLKSVGAQ KDTYTMKEVL 60
FYLGQYIMTK RLYDEKQQHI VYCSNDLLGD LFGVPSFSVK EHRKIYTMIY RNLVVVNQQE 120
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Protein Fasta Sequence



>IUUC-Pab-097696|E3,RING|Pongo abelii
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Nucleotide Sequence
(Fasta)
CGGAGATCCA TATTTGTCGC GGTTTCCACC GCGAGCGAGA AGTGTAAACA CAAGAAATAC 60
AAACATAGCG CAACGGCTAA AGGAGTGTGA CAGCGCCAAA CCTGGCTGGC TCCGCGCCGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Pab-097696|E3,RING|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR028340--Mdm2
IPR015459--MDM2_E3_ligase
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0005730--C:nucleolus
GO:0043234--C:protein complex
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0003283--P:atrial septum development
GO:0003181--P:atrioventricular valve morphogenesis
GO:0001568--P:blood vessel development
GO:0001974--P:blood vessel remodeling
GO:0060411--P:cardiac septum morphogenesis
GO:0071456--P:cellular response to hypoxia
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0003203--P:endocardial cushion morphogenesis
GO:0045184--P:establishment of protein localization
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0018205--P:peptidyl-lysine modification
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0006461--P:protein complex assembly
GO:0031648--P:protein destabilization
GO:0034504--P:protein localization to nucleus
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0002027--P:regulation of heart rate
GO:0046677--P:response to antibiotic
GO:0007089--P:traversing start control point of mitotic cell cycle
GO:0003281--P:ventricular septum development

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002039 Ailuropoda melanoleuca 94.12 0.00e+00 815.00
IUUC-Apl-003193 Anas platyrhynchos 65.39 8.00e-157 546.00
IUUC-Aca-004305 Anolis carolinensis 59.35 1.00e-116 413.00
IUUC-Ame-010675 Astyanax mexicanus 45.42 2.00e-85 310.00
IUUC-Bta-013270 Bos taurus 93.50 0.00e+00 781.00
IUUC-Cja-019744 Callithrix jacchus 95.94 0.00e+00 813.00
IUUC-Cfa-020807 Canis familiaris 91.81 0.00e+00 744.00
IUUC-Cpo-022182 Cavia porcellus 89.23 0.00e+00 741.00
IUUC-Csa-023541 Chlorocebus sabaeus 98.78 0.00e+00 847.00
IUUC-Cho-024831 Choloepus hoffmanni 74.64 2.00e-90 325.00
IUUC-Csv-026151 Ciona savignyi 31.17 4.00e-11 61.60
IUUC-Dre-028419 Danio rerio 43.33 2.00e-50 193.00
IUUC-Dno-028950 Dasypus novemcinctus 92.48 0.00e+00 806.00
IUUC-Dor-031048 Dipodomys ordii 72.38 2.00e-171 595.00
IUUC-Ete-032264 Echinops telfairi 69.17 8.00e-172 596.00
IUUC-Eca-033301 Equus caballus 83.16 0.00e+00 724.00
IUUC-Eeu-035005 Erinaceus europaeus 80.82 0.00e+00 644.00
IUUC-Fca-035454 Felis catus 93.89 0.00e+00 803.00
IUUC-Fal-036720 Ficedula albicollis 61.79 4.00e-73 268.00
IUUC-Gmo-039296 Gadus morhua 41.20 8.00e-45 173.00
IUUC-Gga-040251 Gallus gallus 65.11 9.00e-151 526.00
IUUC-Gac-041528 Gasterosteus aculeatus 42.93 2.00e-33 136.00
IUUC-Ggo-044948 Gorilla gorilla 90.22 0.00e+00 764.00
IUUC-Hsa-046376 Homo sapiens 98.79 0.00e+00 862.00
IUUC-Itr-048328 Ictidomys tridecemlineatus 92.51 0.00e+00 756.00
IUUC-Lch-050037 Latimeria chalumnae 58.16 3.00e-116 411.00
IUUC-Loc-051837 Lepisosteus oculatus 51.01 1.00e-113 403.00
IUUC-Laf-053483 Loxodonta africana 85.77 0.00e+00 734.00
IUUC-Mcc-055294 Macaca mulatta 98.99 0.00e+00 862.00
IUUC-Mga-060007 Meleagris gallopavo 64.10 3.00e-143 501.00
IUUC-Mmr-060673 Microcebus murinus 94.70 0.00e+00 819.00
IUUC-Mdo-063057 Monodelphis domestica 74.19 0.00e+00 657.00
IUUC-Mmu-063207 Mus musculus 80.44 0.00e+00 631.00
IUUC-Mpu-065836 Mustela putorius furo 92.67 0.00e+00 811.00
IUUC-Mlu-068193 Myotis lucifugus 89.29 0.00e+00 770.00
IUUC-Nle-069927 Nomascus leucogenys 99.20 0.00e+00 865.00
IUUC-Opr-070590 Ochotona princeps 85.45 0.00e+00 702.00
IUUC-Ont-071984 Oreochromis niloticus 40.73 9.00e-73 267.00
IUUC-Oan-072744 Ornithorhynchus anatinus 72.62 1.00e-160 559.00
IUUC-Ocu-074071 Oryctolagus cuniculus 93.33 0.00e+00 782.00
IUUC-Ola-087329 Oryzias latipes 41.58 1.00e-71 263.00
IUUC-Oga-088135 Otolemur garnettii 84.85 0.00e+00 737.00
IUUC-Oar-089726 Ovis aries 92.93 0.00e+00 816.00
IUUC-Ptr-091399 Pan troglodytes 99.20 0.00e+00 866.00
IUUC-Pan-092720 Papio anubis 98.99 0.00e+00 862.00
IUUC-Psi-093591 Pelodiscus sinensis 66.96 2.00e-130 458.00
IUUC-Pma-094500 Petromyzon marinus 62.50 9.00e-19 86.70
IUUC-Pfo-096316 Poecilia formosa 41.39 3.00e-72 265.00
IUUC-Pca-100974 Procavia capensis 83.33 0.00e+00 762.00
IUUC-Pva-102488 Pteropus vampyrus 86.72 0.00e+00 710.00
IUUC-Rno-105641 Rattus norvegicus 83.06 0.00e+00 664.00
IUUC-Sha-107314 Sarcophilus harrisii 73.74 0.00e+00 678.00
IUUC-Sar-112938 Sorex araneus 85.71 0.00e+00 739.00
IUUC-Ssc-115495 Sus scrofa 92.87 0.00e+00 768.00
IUUC-Tgu-116623 Taeniopygia guttata 63.56 1.00e-149 522.00
IUUC-Tru-117820 Takifugu rubripes 39.73 1.00e-71 263.00
IUUC-Tsy-119162 Tarsius syrichta 68.66 6.00e-91 327.00
IUUC-Tbe-127816 Tupaia belangeri 91.63 1.00e-116 413.00
IUUC-Ttr-129194 Tursiops truncatus 82.96 0.00e+00 664.00
IUUC-Vpa-130326 Vicugna pacos 87.47 0.00e+00 728.00
IUUC-Xtr-132216 Xenopus tropicalis 56.83 6.00e-119 421.00
Created Date 25-Jun-2017

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