iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000004490.5	ENSBTAT00000062975.1	ENSBTAP00000053970.1
ENSBTAG00000004490.5	ENSBTAT00000005888.4	ENSBTAP00000005888.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.20e-07	29.8	11	76
E3 activity/RING/RING	2.10e-07	31.5	16	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk.....tcPvtrqplteedlvPnltlrrliq 66
            ee++CpI l++ +dP ++ +G+ +  s+I +   sg+      +cP++++ ++ ++++Pn  l +l++
   Q: 11   QEEMICPICLDILQDPATIDCGHNFCLSCITQ---SGEAadsvlKCPLCNKIVKRDTITPNWLLVNLVE 76
           689***************************87...4444566999****************99988776 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl+ ++d p + +CgH f+++C+    ++   +    +CPlC+
   Q: 16   CPICLDILQD-PATIDCGHNFCLSCI---TQSGEAADSVLKCPLCN 57
           **********.9*************9...455667888889****7 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MAHQQFTGKL QEEMICPICL DILQDPATID CGHNFCLSCI TQSGEAADSV LKCPLCNKIV 60
KRDTITPNWL LVNLVEKIQA MDPSDMQPET EELRCLRHGE KCHYFCEVDG KFLCVVCRES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCATC AACAGTTTAC CGGTAAGCTT CAAGAAGAAA TGATTTGCCC CATATGCTTG 60
GATATTCTGC AGGACCCTGC TACCATTGAC TGCGGGCACA ACTTCTGCCT CAGTTGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:0032897--P:negative regulation of viral transcription
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:1902186--P:regulation of viral release from host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-024490	Choloepus hoffmanni	43.72	3.00e-80	291.00
IUUC-Dno-029706	Dasypus novemcinctus	62.93	1.00e-118	419.00
IUUC-Dor-031004	Dipodomys ordii	56.88	6.00e-99	353.00
IUUC-Ggo-045224	Gorilla gorilla	63.12	1.00e-105	376.00
IUUC-Hsa-046727	Homo sapiens	63.44	4.00e-106	378.00
IUUC-Itr-049020	Ictidomys tridecemlineatus	59.92	1.00e-178	619.00
IUUC-Laf-053632	Loxodonta africana	61.10	5.00e-159	553.00
IUUC-Mmu-063149	Mus musculus	53.63	4.00e-150	524.00
IUUC-Nle-069068	Nomascus leucogenys	62.81	1.00e-105	376.00
IUUC-Opr-070792	Ochotona princeps	50.48	1.00e-72	266.00
IUUC-Ocu-074338	Oryctolagus cuniculus	60.00	7.00e-109	387.00
IUUC-Oar-089628	Ovis aries	87.62	0.00e+00	887.00
IUUC-Ptr-090661	Pan troglodytes	63.44	8.00e-107	380.00
IUUC-Pan-091882	Papio anubis	56.75	1.00e-139	489.00
IUUC-Pab-098566	Pongo abelii	61.56	2.00e-113	402.00
IUUC-Rno-104874	Rattus norvegicus	51.87	2.00e-137	482.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence