iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000028397.1	ENSSTOT00000023704.1	ENSSTOP00000022741.1
ENSSTOG00000028397.1	ENSSTOT00000027203.1	ENSSTOP00000015489.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.40e-08	33.5	16	57
E3 activity/RING/U-box	9.10e-06	25.7	11	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC + ++d p++ +CgH f+  C+ ++ g    s  +f+CPlC+
   Q: 16   CPICTDFLQD-PVTIDCGHNFCNRCITRI-GEA--SGSFFKCPLCN 57
           ****9999**.999***************.444..89999*****7 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk..tcPvtrqplteedlvPnltlrrliq 66
            ee +CpI  +  +dPv++ +G+ +  ++I +  + +g+  +cP++++++ ++++ Pn  l +l++
   Q: 11   QEEVICPICTDFLQDPVTIDCGHNFCNRCITRIGEASGSffKCPLCNSSV-NKTFRPNWLLVNLVK 75
           6899****************************777777799*******99.788888887766665 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MASQQFSSQL QEEVICPICT DFLQDPVTID CGHNFCNRCI TRIGEASGSF FKCPLCNSSV 60
NKTFRPNWLL VNLVKKIQAM SASEEQPERD ELKCQRHGEK LYYFCEHSGN FLCVMCCESE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCAGCC AACAGTTTTC CAGCCAACTG CAGGAAGAAG TAATCTGCCC CATCTGCACA 60
GACTTTCTGC AGGACCCTGT CACCATAGAC TGTGGACACA ATTTCTGCAA CAGATGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:0032897--P:negative regulation of viral transcription
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:1902186--P:regulation of viral release from host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013042	Bos taurus	59.92	1.00e-178	619.00
IUUC-Cho-024490	Choloepus hoffmanni	50.00	3.00e-83	301.00
IUUC-Dno-029706	Dasypus novemcinctus	58.44	5.00e-108	384.00
IUUC-Dor-031004	Dipodomys ordii	53.99	9.00e-98	349.00
IUUC-Ete-032890	Echinops telfairi	57.31	2.00e-48	186.00
IUUC-Ggo-045224	Gorilla gorilla	63.61	6.00e-107	380.00
IUUC-Hsa-046467	Homo sapiens	63.91	2.00e-108	385.00
IUUC-Laf-053632	Loxodonta africana	59.84	2.00e-160	558.00
IUUC-Mmu-063149	Mus musculus	50.20	3.00e-143	501.00
IUUC-Nle-069068	Nomascus leucogenys	64.22	2.00e-106	379.00
IUUC-Opr-070792	Ochotona princeps	49.69	2.00e-74	271.00
IUUC-Ocu-074338	Oryctolagus cuniculus	59.15	3.00e-110	391.00
IUUC-Oar-089628	Ovis aries	61.48	0.00e+00	627.00
IUUC-Ptr-090661	Pan troglodytes	63.91	4.00e-107	381.00
IUUC-Pan-091882	Papio anubis	55.79	1.00e-130	459.00
IUUC-Pab-098566	Pongo abelii	62.08	4.00e-111	394.00
IUUC-Rno-104874	Rattus norvegicus	47.44	6.00e-129	454.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence