iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028232

Ensembl Protein ID

ENSDARP00000027152.9

UniProt Accession

Q5SQE2; STB5L_DANRE

Genbank Protein ID

CAI11695.1; CAI11695.1; CAI20992.1; CAI20992.1

Protein Name

Syntaxin-binding protein 5-like

Genbank Nucleotide ID

AL772198; BX322637; BX322637; AL772198

Gene Name

stxbp5l; si:ch211-194d6.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000006383.11	ENSDART00000017292.9	ENSDARP00000027152.9
ENSDARG00000006383.11	ENSDART00000138602.1	ENSDARP00000117512.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-13	49.7	454	479

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 11   f.....sd.tllvsGsdDgtikvWDl 30
           +     +   ++++G  Dg+ik WD 
   Q: 454  WtvgsqTYpEIIITGHADGSIKFWDA 479
           666643223669*************5 PP

Organism

Danio rerio

Functional Description
(View)

May play a role in vesicle trafficking and exocytosis.

Protein Sequence
(Fasta)

MKKFRKVLDG LTTSSPVNPG GSPGCGSAAG TPSAAPTPRE LEIQETLMSE HFQICKTVRH 60
GFPYQPTALA FDPVQKILAI GSRSGGIRMY PFLSFPHLGR PGVDCHSQHE SGAAVLQMQF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAAGT TTCGGAAGGT TTTGGACGGG TTGACCACTT CTTCACCTGT CAATCCAGGT 60
GGGTCTCCCG GTTGCGGCAG TGCGGCCGGG ACCCCCAGTG CGGCACCAAC ACCGCGCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-1003--Cell membrane
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0268--Exocytosis
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR000664--Lethal2_giant
IPR013577--LLGL2
IPR001388--Synaptobrevin
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50892--V_SNARE
PS00678--WD_REPEATS_1
PS50294--WD_REPEATS_REGION

Pfam

PF08366--LLGL
PF00400--WD40

PRINTS

PR00962--LETHAL2GIANT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0005096--F:GTPase activator activity
GO:0017137--F:Rab GTPase binding
GO:0019905--F:syntaxin binding
GO:0006887--P:exocytosis
GO:0015031--P:protein transport
GO:0017157--P:regulation of exocytosis
GO:0050708--P:regulation of protein secretion

KEGG

dre:567605

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003824	Anas platyrhynchos	71.82	0.00e+00	1484.00
IUUC-Aca-004971	Anolis carolinensis	66.70	0.00e+00	1384.00
IUUC-Ame-011870	Astyanax mexicanus	76.21	0.00e+00	1605.00
IUUC-Bta-013516	Bos taurus	70.00	0.00e+00	1608.00
IUUC-Cfa-020684	Canis familiaris	69.80	0.00e+00	1614.00
IUUC-Cpo-021931	Cavia porcellus	67.79	0.00e+00	1458.00
IUUC-Csa-024071	Chlorocebus sabaeus	70.33	0.00e+00	1658.00
IUUC-Cho-025086	Choloepus hoffmanni	66.55	0.00e+00	1476.00
IUUC-Dno-029242	Dasypus novemcinctus	72.02	0.00e+00	1629.00
IUUC-Eeu-034943	Erinaceus europaeus	81.60	0.00e+00	729.00
IUUC-Fal-036915	Ficedula albicollis	70.94	0.00e+00	1650.00
IUUC-Gga-040529	Gallus gallus	72.37	0.00e+00	1654.00
IUUC-Gac-042416	Gasterosteus aculeatus	85.33	0.00e+00	1897.00
IUUC-Ggo-044575	Gorilla gorilla	69.47	0.00e+00	1655.00
IUUC-Hsa-045781	Homo sapiens	69.55	0.00e+00	1655.00
IUUC-Lch-050258	Latimeria chalumnae	70.18	0.00e+00	1292.00
IUUC-Loc-051905	Lepisosteus oculatus	70.63	0.00e+00	1181.00
IUUC-Laf-053669	Loxodonta africana	69.06	0.00e+00	1582.00
IUUC-Mcc-055188	Macaca mulatta	70.33	0.00e+00	1660.00
IUUC-Mmr-061273	Microcebus murinus	68.41	0.00e+00	1607.00
IUUC-Mdo-062223	Monodelphis domestica	72.37	0.00e+00	1515.00
IUUC-Mmu-063800	Mus musculus	70.64	0.00e+00	1662.00
IUUC-Mlu-067278	Myotis lucifugus	70.33	0.00e+00	1656.00
IUUC-Nle-069733	Nomascus leucogenys	69.64	0.00e+00	1656.00
IUUC-Opr-070840	Ochotona princeps	57.16	0.00e+00	863.00
IUUC-Ont-072455	Oreochromis niloticus	74.91	0.00e+00	1561.00
IUUC-Ocu-074214	Oryctolagus cuniculus	69.72	0.00e+00	1620.00
IUUC-Ola-087301	Oryzias latipes	83.00	0.00e+00	1764.00
IUUC-Oga-089148	Otolemur garnettii	71.30	0.00e+00	1688.00
IUUC-Oar-090261	Ovis aries	71.27	0.00e+00	1583.00
IUUC-Ptr-090697	Pan troglodytes	69.55	0.00e+00	1655.00
IUUC-Pan-092899	Papio anubis	70.13	0.00e+00	1648.00
IUUC-Psi-093249	Pelodiscus sinensis	73.53	0.00e+00	1652.00
IUUC-Pfo-096605	Poecilia formosa	81.36	0.00e+00	1582.00
IUUC-Pva-102704	Pteropus vampyrus	62.43	0.00e+00	1381.00
IUUC-Pte-104412	Pyrenophora teres	20.66	4.00e-15	77.40
IUUC-Rno-105297	Rattus norvegicus	71.42	0.00e+00	1556.00
IUUC-Sha-107086	Sarcophilus harrisii	67.48	0.00e+00	1428.00
IUUC-Tgu-117382	Taeniopygia guttata	71.39	0.00e+00	1432.00
IUUC-Tru-118317	Takifugu rubripes	82.90	0.00e+00	1833.00
IUUC-Ttr-129239	Tursiops truncatus	71.16	0.00e+00	1584.00
IUUC-Vpa-130524	Vicugna pacos	66.67	0.00e+00	1477.00
IUUC-Xtr-132634	Xenopus tropicalis	64.95	0.00e+00	1528.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence