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Tag Content
UUCD2 ID IUUC-Ptr-091485
UUCD1 version UUC-PaT-00405
Ensembl Protein ID ENSPTRP00000019403.2
UniProt Accession H2QGV5; H2QGV5_PANTR
Genbank Protein ID ENSPTRP00000019403
Protein Name Nitric oxide synthase-interacting protein
Genbank Nucleotide ID AACZ03119585
Gene Name NOSIP
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPTRG00000011304.3 ENSPTRT00000021011.2 ENSPTRP00000019403.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 2.80e-16 59.4 40 79
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk 41
           v ++ +C +sl++ +dPvv+p+G+ y+r++I +++ +++k
   Q: 40   VKDFDCCCLSLQPCHDPVVTPDGYLYEREAILEYILHQKK 79
           567789*****************************99887 PP
   
Organism Pan troglodytes
Functional Description
(View)

Functional Description


     Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
 Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
Protein Sequence
(Fasta)
MTRHGKNCTA GAVYTYHEKK KDTAASGYGT QNIRLSRDAV KDFDCCCLSL QPCHDPVVTP 60
DGYLYEREAI LEYILHQKKE IARQMKAYEK QRGTRREEQK ELQRAASQDH VRGFLEKESA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ptr-091485|E3,U-box|Pan troglodytes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CACAGTTGAA GAAGCGACCG AGGGACTGGG AGTCGTTAGT GAGGTGAGTT CGAGGCGGTG 60
CAGGAAGAGT GTTGCTGGGA TCGCTTTCCT GCGGGCTAGA GGCCTGGGGT CTTGAGGGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ptr-091485|E3,U-box|Pan troglodytes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
Interpro

IPR016818--Nitric_oxide_synth-interacting
IPR031790--Znf-NOSIP
IPR013083--Znf_RING/FYVE/PHD
Pfam

PF15906--zf-NOSIP
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003723--F:RNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0051001--P:negative regulation of nitric-oxide synthase activity
GO:0016567--P:protein ubiquitination
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000769 Aegilops tauschii 46.51 1.00e-16 81.30
IUUC-Aml-002069 Ailuropoda melanoleuca 88.54 8.00e-159 552.00
IUUC-Atr-002661 Amborella trichopoda 31.85 2.00e-28 119.00
IUUC-Aca-004630 Anolis carolinensis 74.75 1.00e-132 465.00
IUUC-Aly-006316 Arabidopsis lyrata 29.74 3.00e-26 112.00
IUUC-Ath-007000 Arabidopsis thaliana 29.41 7.00e-26 110.00
IUUC-Acl-008175 Aspergillus clavatus 32.03 2.00e-06 47.00
IUUC-Afl-008440 Aspergillus flavus 33.90 4.00e-06 45.40
IUUC-Afu-009012 Aspergillus fumigatus 32.31 1.00e-06 47.40
IUUC-Ani-009153 Aspergillus nidulans 30.40 9.00e-03 34.70
IUUC-Ang-009556 Aspergillus niger 34.78 3.00e-06 45.80
IUUC-Aor-009892 Aspergillus oryzae 33.90 5.00e-06 45.40
IUUC-Ate-010473 Aspergillus terreus 35.37 1.00e-04 41.60
IUUC-Ame-011874 Astyanax mexicanus 62.50 2.00e-106 378.00
IUUC-Bgr-012090 Blumeria graminis 27.46 3.00e-07 48.90
IUUC-Bta-012956 Bos taurus 93.38 2.00e-165 574.00
IUUC-Bci-013897 Botrytis cinerea 42.50 7.00e-10 58.20
IUUC-Bdi-014968 Brachypodium distachyon 29.73 6.00e-31 127.00
IUUC-Bol-015578 Brassica oleracea 30.39 9.00e-31 127.00
IUUC-Bra-017234 Brassica rapa 30.39 9.00e-31 127.00
IUUC-Cel-018637 Caenorhabditis elegans 38.58 2.00e-52 199.00
IUUC-Cja-019632 Callithrix jacchus 96.68 5.00e-173 599.00
IUUC-Cfa-020192 Canis familiaris 91.69 7.00e-164 569.00
IUUC-Cpo-021939 Cavia porcellus 88.04 5.00e-152 530.00
IUUC-Cre-023005 Chlamydomonas reinhardtii 33.89 2.00e-41 162.00
IUUC-Csa-023802 Chlorocebus sabaeus 98.01 1.00e-174 605.00
IUUC-Cho-024637 Choloepus hoffmanni 74.19 3.00e-78 284.00
IUUC-Cin-025180 Ciona intestinalis 51.82 2.00e-83 301.00
IUUC-Csv-026206 Ciona savignyi 53.06 3.00e-40 157.00
IUUC-Cgl-026696 Colletotrichum gloeosporioides 25.74 4.00e-12 65.50
IUUC-Cne-026827 Cryptococcus neoformans 36.36 9.00e-07 47.80
IUUC-Dre-028092 Danio rerio 64.94 1.00e-113 402.00
IUUC-Dno-029501 Dasypus novemcinctus 85.10 2.00e-136 479.00
IUUC-Dor-030542 Dipodomys ordii 89.44 1.00e-159 555.00
IUUC-Dse-031188 Dothistroma septosporum 23.31 1.00e-13 70.50
IUUC-Dme-031734 Drosophila melanogaster 47.90 4.00e-76 277.00
IUUC-Eca-033577 Equus caballus 92.69 1.00e-165 575.00
IUUC-Fca-035761 Felis catus 92.36 9.00e-164 568.00
IUUC-Fox-037703 Fusarium oxysporum 27.95 4.00e-14 72.00
IUUC-Fso-038208 Fusarium solani 28.47 5.00e-13 68.60
IUUC-Gmo-038523 Gadus morhua 60.42 2.00e-61 228.00
IUUC-Ggr-040087 Gaeumannomyces graminis 41.03 4.00e-10 58.50
IUUC-Gac-042621 Gasterosteus aculeatus 59.75 3.00e-106 377.00
IUUC-Gma-042698 Glycine max 30.48 1.00e-29 123.00
IUUC-Ggo-045357 Gorilla gorilla 98.67 9.00e-176 608.00
IUUC-Hsa-046195 Homo sapiens 98.67 9.00e-176 608.00
IUUC-Hvu-047174 Hordeum vulgare 30.64 7.00e-32 130.00
IUUC-Itr-048487 Ictidomys tridecemlineatus 92.69 2.00e-159 554.00
IUUC-Lch-050569 Latimeria chalumnae 67.96 2.00e-112 398.00
IUUC-Lpe-050992 Leersia perrieri 34.98 1.00e-22 100.00
IUUC-Loc-052522 Lepisosteus oculatus 68.33 4.00e-112 397.00
IUUC-Lma-053254 Leptosphaeria maculans 25.17 6.00e-13 68.60
IUUC-Laf-053397 Loxodonta africana 92.74 2.00e-164 570.00
IUUC-Mcc-054681 Macaca mulatta 98.01 7.00e-175 606.00
IUUC-Meu-056723 Macropus eugenii 82.18 2.00e-147 514.00
IUUC-Mor-056961 Magnaporthe oryzae 25.48 8.00e-12 64.70
IUUC-Mpo-057359 Magnaporthe poae 28.21 3.00e-06 45.80
IUUC-Mtr-058063 Medicago truncatula 31.40 2.00e-31 129.00
IUUC-Mla-059004 Melampsora laricipopulina 29.71 1.00e-23 103.00
IUUC-Mvi-060460 Microbotryum violaceum 29.17 3.00e-24 105.00
IUUC-Mmr-060847 Microcebus murinus 95.68 5.00e-171 593.00
IUUC-Mdo-062480 Monodelphis domestica 82.84 1.00e-147 515.00
IUUC-Mmu-063809 Mus musculus 89.70 6.00e-158 549.00
IUUC-Mac-064870 Musa acuminata 30.82 5.00e-31 128.00
IUUC-Mpu-066322 Mustela putorius furo 92.41 2.00e-164 571.00
IUUC-Mlu-067556 Myotis lucifugus 89.14 4.00e-153 533.00
IUUC-Nfi-068440 Neosartorya fischeri 32.31 1.00e-06 47.40
IUUC-Ncr-068898 Neurospora crassa 38.46 7.00e-08 51.20
IUUC-Nle-070049 Nomascus leucogenys 98.34 4.00e-175 606.00
IUUC-Opr-070972 Ochotona princeps 86.56 3.00e-151 527.00
IUUC-Ont-071682 Oreochromis niloticus 65.23 7.00e-114 403.00
IUUC-Oan-073296 Ornithorhynchus anatinus 98.31 2.00e-32 131.00
IUUC-Ocu-074218 Oryctolagus cuniculus 89.09 6.00e-131 459.00
IUUC-Oba-075284 Oryza barthii 31.74 1.00e-30 127.00
IUUC-Obr-076651 Oryza brachyantha 31.16 4.00e-33 135.00
IUUC-Ogl-077899 Oryza glaberrima 31.74 1.00e-30 127.00
IUUC-Ogu-078477 Oryza glumaepatula 32.08 5.00e-31 127.00
IUUC-Oin-080011 Oryza indica 31.74 1.00e-30 127.00
IUUC-Olo-080545 Oryza longistaminata 31.66 2.00e-26 113.00
IUUC-Ome-081543 Oryza meridionalis 31.74 1.00e-30 127.00
IUUC-Oni-082955 Oryza nivara 31.74 1.00e-30 127.00
IUUC-Opu-083565 Oryza punctata 31.16 7.00e-31 127.00
IUUC-Oru-084474 Oryza rufipogon 31.74 1.00e-30 127.00
IUUC-Osa-085913 Oryza sativa 31.74 1.00e-30 127.00
IUUC-Ola-086851 Oryzias latipes 66.11 1.00e-116 412.00
IUUC-Olu-087724 Ostreococcus lucimarinus 40.79 9.00e-10 57.40
IUUC-Oga-087970 Otolemur garnettii 93.71 2.00e-166 577.00
IUUC-Oar-089756 Ovis aries 89.77 9.00e-154 535.00
IUUC-Pan-091832 Papio anubis 98.34 3.00e-175 607.00
IUUC-Pma-094551 Petromyzon marinus 60.59 1.00e-102 365.00
IUUC-Pno-094830 Phaeosphaeria nodorum 34.31 1.00e-08 53.90
IUUC-Ppa-095255 Physcomitrella patens 29.67 1.00e-29 123.00
IUUC-Pfo-096373 Poecilia formosa 64.38 2.00e-113 402.00
IUUC-Pab-098247 Pongo abelii 98.67 8.00e-176 609.00
IUUC-Pop-099186 Populus trichocarpa 30.53 1.00e-28 120.00
IUUC-Pca-100677 Procavia capensis 88.73 4.00e-133 466.00
IUUC-Ppe-101403 Prunus persica 29.69 2.00e-29 122.00
IUUC-Pva-103000 Pteropus vampyrus 92.36 3.00e-164 570.00
IUUC-Pgr-103663 Puccinia graminis 30.03 4.00e-28 119.00
IUUC-Ptt-103712 Puccinia triticina 40.00 5.00e-09 54.70
IUUC-Pte-104287 Pyrenophora teres 25.70 6.00e-17 81.60
IUUC-Pyt-104579 Pyrenophora triticirepentis 24.73 4.00e-13 68.60
IUUC-Rno-106069 Rattus norvegicus 90.70 3.00e-159 553.00
IUUC-Sha-106553 Sarcophilus harrisii 81.85 2.00e-146 511.00
IUUC-Smo-108874 Selaginella moellendorffii 31.10 2.00e-34 139.00
IUUC-Sit-110307 Setaria italica 31.74 3.00e-30 125.00
IUUC-Sly-111094 Solanum lycopersicum 31.68 6.00e-32 130.00
IUUC-Stu-112363 Solanum tuberosum 32.34 5.00e-32 131.00
IUUC-Sar-113480 Sorex araneus 91.03 3.00e-151 527.00
IUUC-Sbi-113939 Sorghum bicolor 31.74 1.00e-30 127.00
IUUC-Ssc-115644 Sus scrofa 93.69 1.00e-166 578.00
IUUC-Tru-118781 Takifugu rubripes 65.05 9.00e-117 412.00
IUUC-Tni-119672 Tetraodon nigroviridis 72.41 3.00e-32 129.00
IUUC-Tca-121795 Theobroma cacao 31.77 3.00e-33 135.00
IUUC-Tre-122037 Trichoderma reesei 36.36 2.00e-08 53.50
IUUC-Tvi-122524 Trichoderma virens 26.80 1.00e-16 80.50
IUUC-Tae-122828 Triticum aestivum 30.98 4.00e-32 131.00
IUUC-Tur-126387 Triticum urartu 30.53 4.00e-28 119.00
IUUC-Tme-127111 Tuber melanosporum 40.00 1.00e-09 57.40
IUUC-Ttr-128227 Tursiops truncatus 92.03 7.00e-163 565.00
IUUC-Vda-129924 Verticillium dahliae 26.15 1.00e-14 73.90
IUUC-Vpa-130802 Vicugna pacos 92.13 5.00e-41 160.00
IUUC-Vvi-131105 Vitis vinifera 32.19 2.00e-31 129.00
IUUC-Xtr-132830 Xenopus tropicalis 64.49 2.00e-118 418.00
IUUC-Xma-133618 Xiphophorus maculatus 64.80 1.00e-107 382.00
IUUC-Zma-135389 Zea mays 30.82 6.00e-30 124.00
Created Date 25-Jun-2017

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