iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000013078.1	ENSSHAT00000015470.1	ENSSHAP00000015343.1
ENSSHAG00000013078.1	ENSSHAT00000015471.1	ENSSHAP00000015344.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-12	47.3	37	66

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d ++++sGs D+++ +W
   Q: 37   GHKDTVYCVAYaKDgKRFASGSADKSVIIW 66
           8***********777*************** PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

IYDLAFKPDG TQLILAAGNR LLVYDTSDGT LIQPLKGHKD TVYCVAYAKD GKRFASGSAD 60
KSVIIWTAKL EGILKYTHND SIQCVSYNPV THQLASCSSN DFGLWSPEQK SVSKHKSNSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATATGACC TTGCATTTAA GCCCGACGGA ACTCAGCTGA TTTTGGCTGC AGGAAACAGA 60
TTACTGGTAG GATTTATTTG ACATTTCCTT TTATAAAGTG CTTTTTCTTT CCTTCTCCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	94.31	0.00e+00	2312.00
IUUC-Apl-003504	Anas platyrhynchos	86.28	0.00e+00	2180.00
IUUC-Aca-004767	Anolis carolinensis	86.00	0.00e+00	2170.00
IUUC-Ame-011642	Astyanax mexicanus	76.34	0.00e+00	1935.00
IUUC-Bta-012969	Bos taurus	91.23	0.00e+00	2216.00
IUUC-Cel-018670	Caenorhabditis elegans	37.88	0.00e+00	879.00
IUUC-Cja-019249	Callithrix jacchus	85.13	0.00e+00	2075.00
IUUC-Cfa-020915	Canis familiaris	94.15	0.00e+00	2252.00
IUUC-Cpo-021888	Cavia porcellus	84.70	0.00e+00	2140.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	48.34	0.00e+00	1144.00
IUUC-Csa-023533	Chlorocebus sabaeus	90.01	0.00e+00	2199.00
IUUC-Cin-025121	Ciona intestinalis	59.21	0.00e+00	1532.00
IUUC-Csv-026240	Ciona savignyi	59.69	0.00e+00	1486.00
IUUC-Dno-029685	Dasypus novemcinctus	89.03	0.00e+00	2179.00
IUUC-Dme-032005	Drosophila melanogaster	24.68	2.00e-08	55.50
IUUC-Ete-032682	Echinops telfairi	83.07	0.00e+00	1656.00
IUUC-Eca-033831	Equus caballus	94.15	0.00e+00	2329.00
IUUC-Eeu-034919	Erinaceus europaeus	83.94	0.00e+00	986.00
IUUC-Fca-036559	Felis catus	92.93	0.00e+00	2288.00
IUUC-Fal-037340	Ficedula albicollis	83.04	0.00e+00	2084.00
IUUC-Gga-040595	Gallus gallus	78.00	0.00e+00	1934.00
IUUC-Ggo-045356	Gorilla gorilla	86.02	0.00e+00	2163.00
IUUC-Hsa-046135	Homo sapiens	85.88	0.00e+00	2160.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	81.02	0.00e+00	1947.00
IUUC-Lch-050183	Latimeria chalumnae	84.29	0.00e+00	1214.00
IUUC-Loc-052049	Lepisosteus oculatus	81.88	0.00e+00	2084.00
IUUC-Laf-053728	Loxodonta africana	93.50	0.00e+00	2333.00
IUUC-Mcc-054971	Macaca mulatta	87.04	0.00e+00	2184.00
IUUC-Meu-056446	Macropus eugenii	90.02	0.00e+00	2251.00
IUUC-Mga-059296	Meleagris gallopavo	83.50	0.00e+00	2172.00
IUUC-Mmr-061232	Microcebus murinus	89.55	0.00e+00	2220.00
IUUC-Mdo-062115	Monodelphis domestica	97.73	0.00e+00	2403.00
IUUC-Mmu-063664	Mus musculus	92.19	0.00e+00	2308.00
IUUC-Mpu-066136	Mustela putorius furo	90.50	0.00e+00	2234.00
IUUC-Mlu-068238	Myotis lucifugus	89.46	0.00e+00	2223.00
IUUC-Nle-069003	Nomascus leucogenys	85.97	0.00e+00	2080.00
IUUC-Ont-072080	Oreochromis niloticus	76.92	0.00e+00	1986.00
IUUC-Oan-072891	Ornithorhynchus anatinus	82.28	0.00e+00	933.00
IUUC-Ocu-074262	Oryctolagus cuniculus	90.56	0.00e+00	2225.00
IUUC-Ola-086538	Oryzias latipes	72.64	0.00e+00	1876.00
IUUC-Oga-088722	Otolemur garnettii	89.39	0.00e+00	2210.00
IUUC-Oar-089249	Ovis aries	87.25	0.00e+00	2143.00
IUUC-Ptr-090752	Pan troglodytes	88.99	0.00e+00	2030.00
IUUC-Pan-092472	Papio anubis	90.09	0.00e+00	2208.00
IUUC-Psi-093335	Pelodiscus sinensis	86.93	0.00e+00	2184.00
IUUC-Pma-094520	Petromyzon marinus	71.19	0.00e+00	1504.00
IUUC-Ppa-095600	Physcomitrella patens	68.48	1.00e-38	151.00
IUUC-Pfo-096526	Poecilia formosa	73.99	0.00e+00	1851.00
IUUC-Pab-098428	Pongo abelii	85.69	0.00e+00	1055.00
IUUC-Pca-100233	Procavia capensis	70.25	0.00e+00	957.00
IUUC-Pva-103064	Pteropus vampyrus	80.41	0.00e+00	1938.00
IUUC-Rno-105764	Rattus norvegicus	92.35	0.00e+00	2300.00
IUUC-Smo-109478	Selaginella moellendorffii	39.25	0.00e+00	730.00
IUUC-Tgu-116870	Taeniopygia guttata	84.47	0.00e+00	2097.00
IUUC-Tru-118661	Takifugu rubripes	71.88	0.00e+00	1843.00
IUUC-Tsy-119640	Tarsius syrichta	76.21	0.00e+00	662.00
IUUC-Tni-120812	Tetraodon nigroviridis	73.46	0.00e+00	1849.00
IUUC-Ttr-128862	Tursiops truncatus	89.19	0.00e+00	2287.00
IUUC-Vpa-130049	Vicugna pacos	86.19	2.00e-160	560.00
IUUC-Xtr-131914	Xenopus tropicalis	79.84	0.00e+00	1999.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence