iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-021141

Ensembl Protein ID

ENSCAFP00000011548.3

UniProt Accession

E2R3X1; E2R3X1_CANLF

Genbank Protein ID

ENSCAFP00000011548

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03010022

Gene Name

ARHGAP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000007789.4	ENSCAFT00000012463.4	ENSCAFP00000011548.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.50e-11	43.2	731	785

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +k ++ y+ ea+++ eL+++ G + + + +++ + gWl+g  +l+gkrGl+P+n+v+ 
   Q: 731  RKARAVYPCEAEHSSELSFEIGAIFEDV-QTSREPGWLEG--TLNGKRGLIPQNYVKL 785
           67899***********************.***********..8*************85 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MGLQPLEFSD CYLDSPWFRE RIRAHEAELE RTNKFIKELI KDGKNLIAAT KSLSAAQRKF 60
AHSLRDFKFE FIGDAETDDE RCIDASLREF SNFLKNLEEQ REIMALSVTE TLIKPLEKFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCTGC AGCCTCTGGA GTTCAGCGAC TGCTACCTCG ACAGCCCGTG GTTCAGGGAG 60
AGGATCCGCG CCCACGAAGC GGAGCTGGAG AGGACCAACA AGTTCATAAA AGAGCTCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:0007010--P:cytoskeleton organization
GO:0043066--P:negative regulation of apoptotic process
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001253	Ailuropoda melanoleuca	97.07	0.00e+00	1533.00
IUUC-Apl-003297	Anas platyrhynchos	78.30	0.00e+00	1212.00
IUUC-Aca-005285	Anolis carolinensis	78.63	0.00e+00	1257.00
IUUC-Bta-012379	Bos taurus	93.00	0.00e+00	1390.00
IUUC-Cja-019182	Callithrix jacchus	93.38	0.00e+00	1431.00
IUUC-Csa-023847	Chlorocebus sabaeus	93.32	0.00e+00	1345.00
IUUC-Cin-025725	Ciona intestinalis	39.66	7.00e-146	511.00
IUUC-Dre-027525	Danio rerio	60.71	0.00e+00	878.00
IUUC-Dno-029215	Dasypus novemcinctus	86.02	0.00e+00	933.00
IUUC-Dor-030308	Dipodomys ordii	82.29	0.00e+00	1137.00
IUUC-Ete-032666	Echinops telfairi	80.71	0.00e+00	791.00
IUUC-Eca-033545	Equus caballus	94.14	0.00e+00	1343.00
IUUC-Fca-036457	Felis catus	96.82	0.00e+00	1520.00
IUUC-Fal-036703	Ficedula albicollis	80.56	0.00e+00	1260.00
IUUC-Gga-040830	Gallus gallus	78.91	0.00e+00	1249.00
IUUC-Gac-041728	Gasterosteus aculeatus	56.51	0.00e+00	835.00
IUUC-Ggo-044569	Gorilla gorilla	91.01	0.00e+00	1298.00
IUUC-Hsa-045658	Homo sapiens	93.77	0.00e+00	1415.00
IUUC-Loc-051740	Lepisosteus oculatus	65.99	0.00e+00	996.00
IUUC-Laf-053641	Loxodonta africana	92.62	0.00e+00	1408.00
IUUC-Mcc-055152	Macaca mulatta	93.51	0.00e+00	1480.00
IUUC-Mmr-061434	Microcebus murinus	94.01	0.00e+00	1343.00
IUUC-Mdo-062864	Monodelphis domestica	87.40	0.00e+00	1385.00
IUUC-Mmu-064061	Mus musculus	90.59	0.00e+00	1405.00
IUUC-Mlu-067375	Myotis lucifugus	92.51	0.00e+00	1311.00
IUUC-Nle-069319	Nomascus leucogenys	89.59	0.00e+00	736.00
IUUC-Ont-071443	Oreochromis niloticus	60.94	0.00e+00	905.00
IUUC-Oan-072978	Ornithorhynchus anatinus	83.41	0.00e+00	1110.00
IUUC-Ocu-074591	Oryctolagus cuniculus	86.86	0.00e+00	1285.00
IUUC-Ola-087508	Oryzias latipes	63.84	0.00e+00	770.00
IUUC-Oga-088922	Otolemur garnettii	88.06	0.00e+00	632.00
IUUC-Oar-089531	Ovis aries	93.26	0.00e+00	1420.00
IUUC-Ptr-091149	Pan troglodytes	92.49	0.00e+00	1401.00
IUUC-Pan-092591	Papio anubis	93.77	0.00e+00	1453.00
IUUC-Pma-094731	Petromyzon marinus	31.76	1.00e-19	92.80
IUUC-Pfo-097265	Poecilia formosa	65.83	0.00e+00	820.00
IUUC-Pab-097780	Pongo abelii	93.38	0.00e+00	1413.00
IUUC-Rno-104991	Rattus norvegicus	90.20	0.00e+00	1402.00
IUUC-Sha-107629	Sarcophilus harrisii	84.26	0.00e+00	1135.00
IUUC-Ssc-115511	Sus scrofa	77.35	0.00e+00	733.00
IUUC-Tgu-117458	Taeniopygia guttata	79.54	0.00e+00	1243.00
IUUC-Tru-117724	Takifugu rubripes	63.52	0.00e+00	770.00
IUUC-Tbe-128126	Tupaia belangeri	27.65	3.00e-06	47.00
IUUC-Ttr-129045	Tursiops truncatus	91.01	0.00e+00	1285.00
IUUC-Xtr-132112	Xenopus tropicalis	70.48	0.00e+00	1102.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence