iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020079

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03008226

Gene Name

RNF5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000000774.3	ENSCAFT00000001208.3	ENSCAFP00000001106.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.10e-07	31.1	27	68

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iCle  ++  +v  CgH+++  Cl++w         ++ CP+C+
   Q: 27   CNICLETARE-AVVSVCGHLYCWPCLHQW---LETRPERQECPVCK 68
           99******88.888***************...555888889****7 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAAAEEEDGG PEGPNRERGG AGATFECNIC LETAREAVVS VCGHLYCWPC LHQWLETRPE 60
RQECPVCKAG ISREKVVPLY GRGSQKPQDP RLKTPPRPQG QRPASESRGG FQSFGDTGGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGCCG CGGAGGAGGA GGACGGGGGC CCCGAAGGGC CAAACCGCGA GCGGGGCGGG 60
GCGGGCGCGA CCTTCGAATG TAATATATGC TTGGAGACTG CTCGGGAGGC TGTGGTCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0044390--F:ubiquitin-like protein conjugating enzyme binding
GO:0008270--F:zinc ion binding
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0010507--P:negative regulation of autophagy
GO:0031648--P:protein destabilization
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2000785--P:regulation of autophagosome assembly
GO:0009617--P:response to bacterium

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001155	Aegilops tauschii	51.65	5.00e-24	104.00
IUUC-Aml-001417	Ailuropoda melanoleuca	97.64	4.00e-70	256.00
IUUC-Atr-002444	Amborella trichopoda	48.21	3.00e-26	111.00
IUUC-Aca-004254	Anolis carolinensis	75.86	4.00e-36	143.00
IUUC-Ame-011316	Astyanax mexicanus	70.13	4.00e-57	213.00
IUUC-Bta-013109	Bos taurus	97.87	7.00e-79	285.00
IUUC-Bdi-014313	Brachypodium distachyon	51.65	4.00e-24	104.00
IUUC-Bol-016132	Brassica oleracea	42.86	1.00e-26	113.00
IUUC-Bra-017631	Brassica rapa	47.71	2.00e-26	112.00
IUUC-Cja-019902	Callithrix jacchus	97.16	4.00e-78	283.00
IUUC-Cpo-021320	Cavia porcellus	91.62	1.00e-85	308.00
IUUC-Csa-023595	Chlorocebus sabaeus	97.16	2.00e-78	284.00
IUUC-Dre-027716	Danio rerio	73.33	7.00e-42	163.00
IUUC-Dno-029843	Dasypus novemcinctus	86.52	1.00e-56	211.00
IUUC-Dor-030170	Dipodomys ordii	96.77	3.00e-68	250.00
IUUC-Eca-033642	Equus caballus	98.17	1.00e-91	328.00
IUUC-Eeu-034778	Erinaceus europaeus	97.44	2.00e-63	234.00
IUUC-Fca-036326	Felis catus	97.16	6.00e-79	286.00
IUUC-Fso-038195	Fusarium solani	40.91	4.00e-10	59.30
IUUC-Gac-042258	Gasterosteus aculeatus	79.20	1.00e-55	208.00
IUUC-Ggo-045474	Gorilla gorilla	97.87	6.00e-79	286.00
IUUC-Hsa-046046	Homo sapiens	97.87	7.00e-79	285.00
IUUC-Hvu-047043	Hordeum vulgare	53.41	1.00e-23	103.00
IUUC-Itr-048037	Ictidomys tridecemlineatus	96.67	4.00e-83	300.00
IUUC-Lch-050367	Latimeria chalumnae	71.67	1.00e-46	177.00
IUUC-Lpe-051034	Leersia perrieri	57.47	1.00e-25	109.00
IUUC-Laf-053395	Loxodonta africana	95.74	3.00e-77	280.00
IUUC-Mcc-054833	Macaca mulatta	97.16	2.00e-78	284.00
IUUC-Meu-055984	Macropus eugenii	86.08	4.00e-36	143.00
IUUC-Mdo-062437	Monodelphis domestica	87.20	2.00e-82	297.00
IUUC-Mmu-064159	Mus musculus	95.77	3.00e-78	283.00
IUUC-Mac-065053	Musa acuminata	56.98	5.00e-24	104.00
IUUC-Mlu-067689	Myotis lucifugus	90.74	3.00e-82	297.00
IUUC-Nle-069705	Nomascus leucogenys	97.87	7.00e-79	285.00
IUUC-Opr-070392	Ochotona princeps	77.97	3.00e-20	90.50
IUUC-Ont-072482	Oreochromis niloticus	73.43	7.00e-58	216.00
IUUC-Ocu-074208	Oryctolagus cuniculus	96.45	2.00e-77	281.00
IUUC-Oba-075461	Oryza barthii	52.17	2.00e-24	106.00
IUUC-Obr-076382	Oryza brachyantha	56.32	4.00e-25	107.00
IUUC-Ogl-077553	Oryza glaberrima	55.67	1.00e-26	112.00
IUUC-Ogu-078463	Oryza glumaepatula	55.67	1.00e-26	112.00
IUUC-Oin-080177	Oryza indica	55.67	1.00e-26	112.00
IUUC-Olo-080378	Oryza longistaminata	51.09	5.00e-24	104.00
IUUC-Ome-081605	Oryza meridionalis	55.67	1.00e-26	112.00
IUUC-Oni-082458	Oryza nivara	55.67	3.00e-26	112.00
IUUC-Opu-083362	Oryza punctata	57.47	7.00e-26	110.00
IUUC-Oru-084757	Oryza rufipogon	55.00	4.00e-27	114.00
IUUC-Osa-086198	Oryza sativa	50.44	4.00e-27	115.00
IUUC-Ola-086507	Oryzias latipes	67.88	3.00e-60	224.00
IUUC-Olu-087623	Ostreococcus lucimarinus	49.25	1.00e-16	79.00
IUUC-Oga-088912	Otolemur garnettii	98.58	3.00e-79	287.00
IUUC-Oar-090284	Ovis aries	94.63	1.00e-70	258.00
IUUC-Ptr-090919	Pan troglodytes	97.62	1.00e-69	254.00
IUUC-Pan-092843	Papio anubis	97.16	2.00e-78	284.00
IUUC-Pfo-096818	Poecilia formosa	78.57	8.00e-56	209.00
IUUC-Pab-098244	Pongo abelii	97.16	2.00e-78	284.00
IUUC-Pop-099595	Populus trichocarpa	55.91	4.00e-27	114.00
IUUC-Pca-100319	Procavia capensis	96.34	2.00e-81	294.00
IUUC-Pva-102249	Pteropus vampyrus	92.91	6.00e-72	262.00
IUUC-Rno-106042	Rattus norvegicus	95.77	3.00e-78	283.00
IUUC-Smo-109079	Selaginella moellendorffii	48.19	2.00e-22	100.00
IUUC-Sit-110690	Setaria italica	53.57	2.00e-22	98.60
IUUC-Sly-110917	Solanum lycopersicum	52.94	3.00e-25	108.00
IUUC-Stu-112552	Solanum tuberosum	51.72	4.00e-25	107.00
IUUC-Sbi-114275	Sorghum bicolor	54.02	1.00e-23	103.00
IUUC-Ssc-115934	Sus scrofa	98.58	3.00e-79	287.00
IUUC-Tru-118679	Takifugu rubripes	60.49	1.00e-22	98.20
IUUC-Tsy-119615	Tarsius syrichta	94.37	2.00e-74	270.00
IUUC-Tca-121830	Theobroma cacao	43.80	8.00e-26	110.00
IUUC-Tae-124319	Triticum aestivum	51.65	6.00e-24	103.00
IUUC-Tur-126198	Triticum urartu	51.65	6.00e-24	103.00
IUUC-Tbe-127773	Tupaia belangeri	95.74	1.00e-75	275.00
IUUC-Ttr-128690	Tursiops truncatus	96.58	4.00e-63	233.00
IUUC-Vvi-131225	Vitis vinifera	58.62	5.00e-26	110.00
IUUC-Xtr-132608	Xenopus tropicalis	80.00	2.00e-46	177.00
IUUC-Xma-134225	Xiphophorus maculatus	78.57	5.00e-56	210.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence