iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072337

Ensembl Protein ID

ENSONIP00000011567.1

UniProt Accession

I3JRS2; I3JRS2_ORENI

Genbank Protein ID

ENSONIP00000011567

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AERX01000891

Gene Name

LOC100708129

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000009199.1	ENSONIT00000011576.1	ENSONIP00000011567.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.80e-15	56.0	100	155

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea + d+L++kkGd  ++i  ++++++W+++ +  +g++G +P+n+v+ ++
   Q: 100  FVALYDYEARTADDLSFKKGDRFQII--NNTEGDWWEARSINTGQKGYIPSNYVAPAD 155
           679***********************..8999**********************9875 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MGCVRSKEDK GPALKYRPDN SNATPASSLL GHYGPEPTIL GHSPAMNAHN NSYNSHAAGL 60
TPFGGTSSVM TPFGGASTSF TSVAVNSPFP SVISGGVTFF VALYDYEART ADDLSFKKGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCATGATTCC TTCTTTGGCC TCGTCTGTTC CTCGGTCCTA GTCCGGCTAT TGTTGTGTGT 60
CTTTCGGGGC AACCCTGACC TATCAGCAAG CGGTGATTTC TGATATTTTA AACTGTTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0034334--P:adherens junction maintenance
GO:0060027--P:convergent extension involved in gastrulation
GO:0046777--P:protein autophosphorylation
GO:0045859--P:regulation of protein kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002374	Ailuropoda melanoleuca	84.67	0.00e+00	942.00
IUUC-Apl-004032	Anas platyrhynchos	87.57	0.00e+00	982.00
IUUC-Aca-004255	Anolis carolinensis	85.74	0.00e+00	978.00
IUUC-Ame-010954	Astyanax mexicanus	91.77	0.00e+00	1065.00
IUUC-Bta-013503	Bos taurus	85.01	0.00e+00	942.00
IUUC-Cja-019694	Callithrix jacchus	84.83	0.00e+00	945.00
IUUC-Cfa-020402	Canis familiaris	85.01	0.00e+00	948.00
IUUC-Cpo-022506	Cavia porcellus	84.67	0.00e+00	941.00
IUUC-Csa-023713	Chlorocebus sabaeus	85.37	0.00e+00	944.00
IUUC-Dre-027978	Danio rerio	90.86	0.00e+00	1017.00
IUUC-Dno-029897	Dasypus novemcinctus	84.41	0.00e+00	835.00
IUUC-Dor-030202	Dipodomys ordii	93.36	0.00e+00	894.00
IUUC-Eca-034157	Equus caballus	85.01	0.00e+00	946.00
IUUC-Eeu-034950	Erinaceus europaeus	71.92	1.00e-156	545.00
IUUC-Fca-036233	Felis catus	85.01	0.00e+00	972.00
IUUC-Fal-037461	Ficedula albicollis	86.65	0.00e+00	986.00
IUUC-Gmo-038929	Gadus morhua	90.71	0.00e+00	991.00
IUUC-Gga-041107	Gallus gallus	87.39	0.00e+00	979.00
IUUC-Gac-042321	Gasterosteus aculeatus	92.91	0.00e+00	1040.00
IUUC-Hsa-047010	Homo sapiens	85.19	0.00e+00	956.00
IUUC-Lch-050239	Latimeria chalumnae	86.47	0.00e+00	984.00
IUUC-Loc-052314	Lepisosteus oculatus	88.89	0.00e+00	964.00
IUUC-Laf-053517	Loxodonta africana	83.55	0.00e+00	930.00
IUUC-Mcc-055626	Macaca mulatta	85.37	0.00e+00	945.00
IUUC-Meu-056155	Macropus eugenii	75.83	0.00e+00	724.00
IUUC-Mga-059310	Meleagris gallopavo	87.39	0.00e+00	979.00
IUUC-Mmr-061652	Microcebus murinus	83.73	0.00e+00	951.00
IUUC-Mdo-062963	Monodelphis domestica	83.91	0.00e+00	948.00
IUUC-Mmu-064128	Mus musculus	84.46	0.00e+00	955.00
IUUC-Mpu-065906	Mustela putorius furo	85.01	0.00e+00	947.00
IUUC-Mlu-067035	Myotis lucifugus	84.73	0.00e+00	941.00
IUUC-Nle-069041	Nomascus leucogenys	81.35	0.00e+00	898.00
IUUC-Opr-070299	Ochotona princeps	76.05	0.00e+00	826.00
IUUC-Oan-072997	Ornithorhynchus anatinus	94.34	0.00e+00	910.00
IUUC-Ocu-074171	Oryctolagus cuniculus	83.55	0.00e+00	946.00
IUUC-Oga-087957	Otolemur garnettii	83.36	0.00e+00	944.00
IUUC-Oar-089670	Ovis aries	84.46	0.00e+00	945.00
IUUC-Ptr-091352	Pan troglodytes	85.19	0.00e+00	957.00
IUUC-Pan-092202	Papio anubis	85.37	0.00e+00	945.00
IUUC-Psi-093310	Pelodiscus sinensis	87.20	0.00e+00	993.00
IUUC-Pma-094232	Petromyzon marinus	85.41	0.00e+00	867.00
IUUC-Pfo-097076	Poecilia formosa	90.33	0.00e+00	1047.00
IUUC-Pva-102592	Pteropus vampyrus	79.71	0.00e+00	894.00
IUUC-Rno-105544	Rattus norvegicus	83.18	0.00e+00	941.00
IUUC-Sar-113364	Sorex araneus	80.07	0.00e+00	886.00
IUUC-Tgu-117380	Taeniopygia guttata	86.65	0.00e+00	986.00
IUUC-Tru-117784	Takifugu rubripes	93.60	0.00e+00	1059.00
IUUC-Ttr-128893	Tursiops truncatus	85.01	0.00e+00	946.00
IUUC-Vpa-130060	Vicugna pacos	83.73	0.00e+00	944.00
IUUC-Xtr-132322	Xenopus tropicalis	85.37	0.00e+00	971.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence