iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053974

UUCD1 version

UUC-LoA-00732

Ensembl Protein ID

ENSLAFP00000019779.1

UniProt Accession

G3TW21; G3TW21_LOXAF

Protein Name

Uncharacterized protein

Gene Name

POC1A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000028434.1	ENSLAFT00000026312.1	ENSLAFP00000019779.1
ENSLAFG00000028434.1	ENSLAFT00000033958.1	ENSLAFP00000029197.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-48	160.6	59	88
UBD/Beta-Prp	1.10e-61	209.0	15	152

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d vtc++f ++ +ll+sGs+D+t+++W
   Q: 59   GHKDAVTCVHFsPSgHLLASGSRDKTVRIW 88
           8***********66699************* PP

UBD/Beta-Prp

   S: 90   lkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           +kgh d v+s++fs +++ l+sGs d+ ++vw+++ ++  +  ++gh+++v+cv+++p+g ll+sGs D+tvr+W  + +   + ++  
   Q: 15   FKGHRDAVTSVDFSLNTKQLASGSTDSCLMVWNMKPQSRAY-RFTGHKDAVTCVHFSPSGHLLASGSRDKTVRIWVPNVKGESTAFRA- 101
           55555555555555555555555555555555555555555.5555555555555555555555555555555554444444444444. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvr 229
           ht  v+s+ f s+g++lv++s+d+tvk+w+ ++++ + +l  h ++v++ +
   Q: 102  HTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQKFLFSLSQHINWVRCAK 152
           555555555555555555555555555555555555555555555555544 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

THTLPQEDPS LERHFKGHRD AVTSVDFSLN TKQLASGSTD SCLMVWNMKP QSRAYRFTGH 60
KDAVTCVHFS PSGHLLASGS RDKTVRIWVP NVKGESTAFR AHTATVRSVH FCSDGQSLVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCCACACTC TCCCCCAGGA GGACCCCTCG CTGGAGAGGC ATTTTAAGGG CCACCGAGAT 60
GCAGTTACCA GTGTGGACTT CAGTCTCAAC ACGAAGCAGT TGGGTAAGAG CAGGCATCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000922--C:spindle pole
GO:0003431--P:growth plate cartilage chondrocyte development
GO:0007052--P:mitotic spindle organization
GO:1905515--P:non-motile cilium assembly
GO:0010825--P:positive regulation of centrosome duplication
GO:0007283--P:spermatogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001513	Ailuropoda melanoleuca	83.62	0.00e+00	641.00
IUUC-Apl-003466	Anas platyrhynchos	71.78	8.00e-164	569.00
IUUC-Aca-004323	Anolis carolinensis	66.29	7.00e-160	556.00
IUUC-Bta-012484	Bos taurus	83.87	0.00e+00	672.00
IUUC-Cja-019067	Callithrix jacchus	82.52	0.00e+00	671.00
IUUC-Cfa-020439	Canis familiaris	83.83	0.00e+00	671.00
IUUC-Cpo-021403	Cavia porcellus	81.66	0.00e+00	665.00
IUUC-Cre-022724	Chlamydomonas reinhardtii	49.11	8.00e-102	363.00
IUUC-Csa-023479	Chlorocebus sabaeus	84.05	1.00e-168	585.00
IUUC-Cho-024354	Choloepus hoffmanni	81.00	4.00e-101	360.00
IUUC-Csv-025955	Ciona savignyi	59.16	4.00e-128	451.00
IUUC-Dno-029467	Dasypus novemcinctus	70.32	6.00e-106	376.00
IUUC-Dor-030399	Dipodomys ordii	80.94	0.00e+00	649.00
IUUC-Eca-034425	Equus caballus	84.11	0.00e+00	644.00
IUUC-Eeu-034607	Erinaceus europaeus	71.71	2.00e-149	521.00
IUUC-Fca-035627	Felis catus	84.37	0.00e+00	649.00
IUUC-Fal-037381	Ficedula albicollis	68.87	1.00e-159	555.00
IUUC-Gmo-038489	Gadus morhua	64.16	2.00e-145	508.00
IUUC-Gga-040559	Gallus gallus	69.15	3.00e-155	541.00
IUUC-Gac-041453	Gasterosteus aculeatus	65.10	1.00e-152	532.00
IUUC-Ggo-044773	Gorilla gorilla	83.87	0.00e+00	645.00
IUUC-Hsa-045823	Homo sapiens	84.62	0.00e+00	649.00
IUUC-Itr-048560	Ictidomys tridecemlineatus	83.42	0.00e+00	673.00
IUUC-Lch-050558	Latimeria chalumnae	64.67	1.00e-156	546.00
IUUC-Loc-052836	Lepisosteus oculatus	63.76	4.00e-155	540.00
IUUC-Mcc-055494	Macaca mulatta	82.13	0.00e+00	634.00
IUUC-Meu-056646	Macropus eugenii	75.69	5.00e-127	447.00
IUUC-Mga-059295	Meleagris gallopavo	63.09	2.00e-150	525.00
IUUC-Mmr-061040	Microcebus murinus	84.86	0.00e+00	676.00
IUUC-Mdo-062519	Monodelphis domestica	70.16	3.00e-151	527.00
IUUC-Mmu-063759	Mus musculus	84.72	1.00e-146	512.00
IUUC-Mpu-066442	Mustela putorius furo	84.12	0.00e+00	646.00
IUUC-Mlu-068163	Myotis lucifugus	82.51	0.00e+00	657.00
IUUC-Nle-070160	Nomascus leucogenys	84.37	0.00e+00	649.00
IUUC-Opr-070192	Ochotona princeps	80.75	8.00e-166	576.00
IUUC-Ont-072539	Oreochromis niloticus	73.09	1.00e-132	466.00
IUUC-Ocu-074624	Oryctolagus cuniculus	83.51	1.00e-178	618.00
IUUC-Ola-087268	Oryzias latipes	58.35	4.00e-141	494.00
IUUC-Oga-088964	Otolemur garnettii	78.00	1.00e-179	621.00
IUUC-Oar-090202	Ovis aries	83.86	0.00e+00	648.00
IUUC-Ptr-091164	Pan troglodytes	84.41	0.00e+00	649.00
IUUC-Pan-092805	Papio anubis	83.51	2.00e-167	581.00
IUUC-Psi-093359	Pelodiscus sinensis	77.99	2.00e-140	491.00
IUUC-Pfo-096741	Poecilia formosa	55.24	3.00e-139	488.00
IUUC-Pab-098376	Pongo abelii	84.37	0.00e+00	681.00
IUUC-Pca-101122	Procavia capensis	85.61	0.00e+00	687.00
IUUC-Pva-103104	Pteropus vampyrus	65.26	2.00e-136	478.00
IUUC-Rno-105282	Rattus norvegicus	77.51	5.00e-163	566.00
IUUC-Sha-106840	Sarcophilus harrisii	69.83	4.00e-95	340.00
IUUC-Sar-113262	Sorex araneus	56.58	3.00e-114	405.00
IUUC-Ssc-115392	Sus scrofa	80.71	4.00e-155	540.00
IUUC-Tgu-117340	Taeniopygia guttata	69.15	5.00e-156	543.00
IUUC-Tsy-119404	Tarsius syrichta	75.93	2.00e-172	597.00
IUUC-Tbe-127788	Tupaia belangeri	72.04	4.00e-151	527.00
IUUC-Ttr-128608	Tursiops truncatus	80.15	2.00e-173	601.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence