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Tag Content
iUUCD ID IUUC-Oar-089785
Ensembl Protein ID ENSOARP00000011663.1
UniProt Accession W5PMI8; W5PMI8_SHEEP
Genbank Protein ID ENSOARP00000011663
Protein Name Uncharacterized protein
Genbank Nucleotide ID AMGL01031023
Gene Name CUL5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOARG00000010875.1 ENSOART00000011830.1 ENSOARP00000011663.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 1.80e-230 767.0 22 672
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 2    lreavkkilrqesv.kkeyeelytavynlclsk..vgaklYkklkevleefikqvkkkveesedeq.lLktynreWekfreqlkvlrki 86
           +r +v k+lrqesv k+++ +l+++v+++cl++  + ak++++lke++ efikq++++v +++d++ lLk+y++eW+kf++q+++l+k+
   Q: 22   MRPIVLKLLRQESVtKQQWFDLFSDVHAVCLWDdkGPAKIHQALKEDILEFIKQAQARVLSHQDDTaLLKAYIVEWRKFFTQCDILPKP 110
           7899****************************9999***************************************************** PP
   S: 87   fayldrtyvkk.....skkv..sevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveLslnk...laiyk 165
           f++l+ t ++k     +++v  s vrkL+ld+w+++i+++ik+rl+++++kl++aeR gea+d++l+ gv+es+v+L++n    l+iy+
   Q: 111  FCQLEITLMGKqgsnkKSNVedSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPedkLQIYR 199
           ***********8765544448899*******************************************************99999***** PP
   S: 166  esFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetk....Llevvekeliakhlesllaelvallrdk 250
           ++FE+++l++t++fy++++ ++lq+n+v++Y+k+++a+l+eee+ra ryle+++e++    L+e+++++l++++ e++lae++ +++++
   Q: 200  DNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNsveaLMECCVNALVTSFKETILAECQGMIKRN 288
           *******************************************************999999**************************** PP
   S: 251  ktedlsrmykLlsrvlngleellkeleshikeqgkaalt..aeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfv 337
           +te+l++m++L+++v+ng+e++lk+le+hi ++g+a+++  ae++++d++kyVe+ll+l+n+++klv+eaF++d++Fl+a+dka++++v
   Q: 289  ETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVaaAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVV 377
           **************************************99999********************************************** PP
   S: 338  nknsvlka................akspEllAryiDqlLrks..skglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgk 408
           n+++++k+                +k+pEllA+y+D+lLrk+  sk+lt+ee+ea+l++vllv+ky+++kdvF++y+k hL++RL++++
   Q: 378  NDATIFKLelplkqkgvglktqpeSKCPELLANYCDMLLRKTplSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDI 466
           ***************************************************************************************** PP
   S: 409  sasseaEesviekLkeec.gaeftskLerMfqdlkvSedlnrqFk.eekenteesesvelsvlvLsagaWptasetekvsLPaelekti 495
           sa+se+Ee+++e+L+e++ +a++++kL+rMfqd+kvSedln++Fk ++k+n+ + +++++++++L+agaW+++se++ vsLP+ele++i
   Q: 467  SADSEIEENMVEWLREVGmPADYVNKLARMFQDIKVSEDLNQAFKeMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLI 555
           *********************************************5688888899********************************** PP
   S: 496  ekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnns..ekvsveelkkatelpeeeLrrtlqsLvs.sk.. 579
           +++eefY+++hsgRkL+W+h ++++ +++++++g+y+l+V+tfQ+avL+a+n++  ek+s+e+lk atelp++eLrrtl+sLv+ +k  
   Q: 556  PEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRprEKISFENLKLATELPDAELRRTLWSLVAfPKlk 644
           *****************************************************999****************************99999 PP
   S: 580  kqvlkkepeske...ieeedlfsvNqef 604
           +qvl +ep+ ++   ++e++lfsvNqef
   Q: 645  RQVLLYEPQVNSpkdFTEGTLFSVNQEF 672
           9********977778************9 PP
   
Organism Ovis aries
Protein Sequence
(Fasta)
MATSNLLKNK GSLQFEDKWD FMRPIVLKLL RQESVTKQQW FDLFSDVHAV CLWDDKGPAK 60
IHQALKEDIL EFIKQAQARV LSHQDDTALL KAYIVEWRKF FTQCDILPKP FCQLEITLMG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oar-089785|E3,Cullin|Ovis aries
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCGACGT CTAATCTGTT AAAGGTAAGA CCCTCAGTCC GTCTTGGATT TCTACTCCGG 60
GAGCGGTGGG TTCAGCTCTC GGGGAATGGC TCGGTTCTGG TTCAGCGGCG AAATGGGGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oar-089785|E3,Cullin|Ovis aries
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG oas:101105597
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002082 Ailuropoda melanoleuca 98.85 0.00e+00 1553.00
IUUC-Apl-003564 Anas platyrhynchos 99.61 0.00e+00 1553.00
IUUC-Aca-004319 Anolis carolinensis 99.36 0.00e+00 1566.00
IUUC-Ame-011742 Astyanax mexicanus 96.93 0.00e+00 1531.00
IUUC-Bta-012515 Bos taurus 100.00 0.00e+00 1529.00
IUUC-Cel-018522 Caenorhabditis elegans 51.35 0.00e+00 756.00
IUUC-Cja-018785 Callithrix jacchus 99.87 0.00e+00 1570.00
IUUC-Cfa-020932 Canis familiaris 99.87 0.00e+00 1527.00
IUUC-Cpo-022317 Cavia porcellus 99.74 0.00e+00 1570.00
IUUC-Csa-023949 Chlorocebus sabaeus 100.00 0.00e+00 1573.00
IUUC-Cho-024570 Choloepus hoffmanni 99.53 1.00e-127 449.00
IUUC-Cin-025540 Ciona intestinalis 73.02 9.00e-152 529.00
IUUC-Csv-025978 Ciona savignyi 65.06 0.00e+00 1008.00
IUUC-Dre-027958 Danio rerio 96.92 0.00e+00 1546.00
IUUC-Dno-029195 Dasypus novemcinctus 99.74 0.00e+00 1561.00
IUUC-Dor-030573 Dipodomys ordii 87.25 2.00e-173 602.00
IUUC-Dme-032083 Drosophila melanogaster 68.13 0.00e+00 921.00
IUUC-Ete-032428 Echinops telfairi 82.69 0.00e+00 1237.00
IUUC-Eca-033232 Equus caballus 99.87 0.00e+00 1570.00
IUUC-Eeu-035348 Erinaceus europaeus 100.00 0.00e+00 756.00
IUUC-Fca-035401 Felis catus 99.35 0.00e+00 1534.00
IUUC-Fal-037514 Ficedula albicollis 99.48 0.00e+00 1551.00
IUUC-Gmo-038577 Gadus morhua 94.13 0.00e+00 1495.00
IUUC-Gga-041096 Gallus gallus 99.35 0.00e+00 1554.00
IUUC-Gac-042108 Gasterosteus aculeatus 95.02 0.00e+00 1508.00
IUUC-Ggo-045313 Gorilla gorilla 99.49 0.00e+00 1565.00
IUUC-Hsa-045974 Homo sapiens 100.00 0.00e+00 1573.00
IUUC-Itr-049009 Ictidomys tridecemlineatus 100.00 0.00e+00 1569.00
IUUC-Lch-050615 Latimeria chalumnae 99.08 0.00e+00 1516.00
IUUC-Loc-051807 Lepisosteus oculatus 98.33 0.00e+00 1548.00
IUUC-Laf-053601 Loxodonta africana 99.87 0.00e+00 1560.00
IUUC-Mcc-055260 Macaca mulatta 100.00 0.00e+00 1571.00
IUUC-Meu-056632 Macropus eugenii 99.58 0.00e+00 958.00
IUUC-Mga-059658 Meleagris gallopavo 99.36 0.00e+00 1553.00
IUUC-Mmr-061424 Microcebus murinus 89.73 0.00e+00 1359.00
IUUC-Mdo-061836 Monodelphis domestica 99.62 0.00e+00 1567.00
IUUC-Mmu-063757 Mus musculus 98.46 0.00e+00 1552.00
IUUC-Mpu-065823 Mustela putorius furo 99.74 0.00e+00 1570.00
IUUC-Mlu-066969 Myotis lucifugus 99.48 0.00e+00 1553.00
IUUC-Nle-069943 Nomascus leucogenys 100.00 0.00e+00 1573.00
IUUC-Opr-070820 Ochotona princeps 100.00 0.00e+00 868.00
IUUC-Ont-072527 Oreochromis niloticus 96.03 0.00e+00 1528.00
IUUC-Oan-072743 Ornithorhynchus anatinus 99.60 0.00e+00 1525.00
IUUC-Ocu-074586 Oryctolagus cuniculus 100.00 0.00e+00 1573.00
IUUC-Ola-087526 Oryzias latipes 96.03 0.00e+00 1527.00
IUUC-Oga-088425 Otolemur garnettii 95.36 0.00e+00 1519.00
IUUC-Ptr-091242 Pan troglodytes 100.00 0.00e+00 1573.00
IUUC-Pan-092246 Papio anubis 100.00 0.00e+00 1573.00
IUUC-Psi-094081 Pelodiscus sinensis 99.61 0.00e+00 1558.00
IUUC-Pma-094735 Petromyzon marinus 81.80 0.00e+00 746.00
IUUC-Pfo-097305 Poecilia formosa 95.90 0.00e+00 1518.00
IUUC-Pab-098248 Pongo abelii 93.85 0.00e+00 1452.00
IUUC-Pca-100756 Procavia capensis 88.27 0.00e+00 876.00
IUUC-Pva-102990 Pteropus vampyrus 85.90 0.00e+00 919.00
IUUC-Rno-105887 Rattus norvegicus 98.72 0.00e+00 1554.00
IUUC-Sha-107016 Sarcophilus harrisii 99.62 0.00e+00 1567.00
IUUC-Sar-113558 Sorex araneus 94.17 0.00e+00 1486.00
IUUC-Ssc-115414 Sus scrofa 100.00 0.00e+00 1573.00
IUUC-Tgu-116801 Taeniopygia guttata 98.59 0.00e+00 1545.00
IUUC-Tru-117565 Takifugu rubripes 96.28 0.00e+00 1530.00
IUUC-Tsy-119292 Tarsius syrichta 94.01 0.00e+00 1375.00
IUUC-Tni-120471 Tetraodon nigroviridis 96.16 0.00e+00 1523.00
IUUC-Tbe-127838 Tupaia belangeri 94.23 0.00e+00 1502.00
IUUC-Ttr-128345 Tursiops truncatus 99.49 0.00e+00 1564.00
IUUC-Vpa-130191 Vicugna pacos 90.85 0.00e+00 855.00
IUUC-Xtr-132810 Xenopus tropicalis 98.85 0.00e+00 1558.00
Created Date 25-Jun-2017

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