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Tag Content
UUCD2 ID IUUC-Cja-019207
UUCD1 version UUC-CaJ-00385
Ensembl Protein ID ENSCJAP00000025798.1
UniProt Accession F7CSA7; F7CSA7_CALJA
Genbank Protein ID JAB46102.1
Protein Name E3 ubiquitin-protein ligase CBL
Genbank Nucleotide ID ACFV01080396
Gene Name CBL
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCJAG00000014015.1 ENSCJAT00000027254.1 ENSCJAP00000025794.1
ENSCJAG00000014015.1 ENSCJAT00000027260.1 ENSCJAP00000025798.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 3.10e-07 31.8 383 422
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl  w    + +s  + CP Cr
   Q: 383  CKICAENDKD-VKIEPCGHLMCTSCLTSW----Q-ESEGQGCPFCR 422
           99********.******************....5.555555****8 PP
   
Organism Callithrix jacchus
Protein Sequence
(Fasta)
MAGNVKKSSG AGSGGGSGGS GSGGLIGLMK DAFQPHHHHH HHHHLSPHPP GTVDKKMVEK 60
CWKLMDKVVR LCQNPKLALK NSPPYILDLL PDTYQHLRTI LSRYEGKMET LGENEYFRVF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cja-019207|E3,RING|Callithrix jacchus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCTGCTTCTC TCCCTAGCTC GCAGTTGAGC CGAGCCGGCG CACCCGCCTG GGCTCCAAAC 60
CTGCCCAAGC CATGGCCGGC AACGTAAAGA AGAGCTCTGG GGCCGGGAGC GGCGGCGGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cja-019207|E3,RING|Callithrix jacchus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR009060--UBA-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3
PF00627--UBA
SMART

SM00184--RING
SM00165--UBA
Gene Ontology

GO:0005829--C:cytosol
GO:0016600--C:flotillin complex
GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0016874--F:ligase activity
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0043066--P:negative regulation of apoptotic process
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0048260--P:positive regulation of receptor-mediated endocytosis
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG cjc:100408313
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002357 Ailuropoda melanoleuca 90.96 0.00e+00 1474.00
IUUC-Apl-004041 Anas platyrhynchos 83.92 0.00e+00 1372.00
IUUC-Aca-004899 Anolis carolinensis 80.72 0.00e+00 1253.00
IUUC-Ame-010746 Astyanax mexicanus 59.62 0.00e+00 628.00
IUUC-Bta-012759 Bos taurus 91.27 0.00e+00 1521.00
IUUC-Cel-018674 Caenorhabditis elegans 54.90 3.00e-133 468.00
IUUC-Cfa-020897 Canis familiaris 91.53 0.00e+00 1520.00
IUUC-Cpo-021453 Cavia porcellus 91.08 0.00e+00 1509.00
IUUC-Csa-023136 Chlorocebus sabaeus 97.14 0.00e+00 1615.00
IUUC-Cho-024282 Choloepus hoffmanni 84.73 0.00e+00 1246.00
IUUC-Cin-025574 Ciona intestinalis 71.54 7.00e-178 616.00
IUUC-Csv-025938 Ciona savignyi 69.87 4.00e-173 600.00
IUUC-Cgl-026569 Colletotrichum gloeosporioides 40.43 7.00e-07 49.30
IUUC-Dre-027644 Danio rerio 68.80 0.00e+00 1036.00
IUUC-Dno-030025 Dasypus novemcinctus 92.50 0.00e+00 1476.00
IUUC-Dme-032213 Drosophila melanogaster 74.81 0.00e+00 643.00
IUUC-Ete-033118 Echinops telfairi 79.57 0.00e+00 817.00
IUUC-Eca-033900 Equus caballus 93.54 0.00e+00 1505.00
IUUC-Eeu-035142 Erinaceus europaeus 85.74 0.00e+00 957.00
IUUC-Fca-035455 Felis catus 91.31 0.00e+00 1509.00
IUUC-Fal-037182 Ficedula albicollis 96.75 0.00e+00 902.00
IUUC-Gmo-038698 Gadus morhua 87.30 0.00e+00 870.00
IUUC-Gga-040438 Gallus gallus 83.39 0.00e+00 1392.00
IUUC-Gac-042166 Gasterosteus aculeatus 76.03 0.00e+00 884.00
IUUC-Ggo-045618 Gorilla gorilla 97.03 0.00e+00 1623.00
IUUC-Hsa-046177 Homo sapiens 97.03 0.00e+00 1620.00
IUUC-Itr-048795 Ictidomys tridecemlineatus 96.29 0.00e+00 1012.00
IUUC-Lch-050095 Latimeria chalumnae 74.01 0.00e+00 1171.00
IUUC-Loc-052570 Lepisosteus oculatus 71.35 0.00e+00 1120.00
IUUC-Laf-054008 Loxodonta africana 89.75 0.00e+00 1530.00
IUUC-Mcc-054676 Macaca mulatta 97.03 0.00e+00 1612.00
IUUC-Mga-059239 Meleagris gallopavo 82.33 0.00e+00 1396.00
IUUC-Mmr-060907 Microcebus murinus 91.79 0.00e+00 1519.00
IUUC-Mdo-062595 Monodelphis domestica 87.50 0.00e+00 1403.00
IUUC-Mmu-063725 Mus musculus 90.63 0.00e+00 1576.00
IUUC-Mpu-066771 Mustela putorius furo 90.52 0.00e+00 1523.00
IUUC-Mlu-067206 Myotis lucifugus 76.26 0.00e+00 1082.00
IUUC-Nle-069285 Nomascus leucogenys 93.96 0.00e+00 1515.00
IUUC-Opr-071026 Ochotona princeps 92.17 0.00e+00 1482.00
IUUC-Ont-071954 Oreochromis niloticus 70.11 0.00e+00 1041.00
IUUC-Ocu-074657 Oryctolagus cuniculus 92.01 0.00e+00 1462.00
IUUC-Ola-087165 Oryzias latipes 66.91 0.00e+00 1061.00
IUUC-Oga-088198 Otolemur garnettii 82.17 0.00e+00 1330.00
IUUC-Oar-090258 Ovis aries 91.33 0.00e+00 1460.00
IUUC-Ptr-090710 Pan troglodytes 97.03 0.00e+00 1620.00
IUUC-Pan-092785 Papio anubis 97.03 0.00e+00 1612.00
IUUC-Pfo-096990 Poecilia formosa 90.16 0.00e+00 818.00
IUUC-Pab-098526 Pongo abelii 96.81 0.00e+00 1616.00
IUUC-Pca-100984 Procavia capensis 78.75 8.00e-171 593.00
IUUC-Pva-102352 Pteropus vampyrus 97.08 0.00e+00 896.00
IUUC-Rno-105876 Rattus norvegicus 90.20 0.00e+00 1548.00
IUUC-Sha-107588 Sarcophilus harrisii 85.35 0.00e+00 1214.00
IUUC-Sar-112959 Sorex araneus 88.02 0.00e+00 1422.00
IUUC-Ssc-115261 Sus scrofa 91.51 0.00e+00 1533.00
IUUC-Tgu-116580 Taeniopygia guttata 81.49 0.00e+00 1313.00
IUUC-Tru-118731 Takifugu rubripes 68.12 0.00e+00 1036.00
IUUC-Tsy-118982 Tarsius syrichta 88.01 0.00e+00 1068.00
IUUC-Tni-120725 Tetraodon nigroviridis 68.41 0.00e+00 1030.00
IUUC-Tbe-128018 Tupaia belangeri 95.43 0.00e+00 1164.00
IUUC-Ttr-128927 Tursiops truncatus 93.01 0.00e+00 1574.00
IUUC-Vpa-130369 Vicugna pacos 93.01 0.00e+00 1446.00
IUUC-Xtr-132474 Xenopus tropicalis 73.84 0.00e+00 1143.00
Created Date 25-Jun-2017

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