iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-041996

Ensembl Protein ID

ENSGACP00000004599.1

UniProt Accession

G3NGZ2; G3NGZ2_GASAC

Protein Name

Inhibitor of growth protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000003510.1	ENSGACT00000004613.1	ENSGACP00000004599.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.50e-08	34.4	203	250

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+ C++l     +p+ + w+CpkCr 
   Q: 203  TYC-LCEQVSYGE--MIGCDNdeCPiEWFHFSCVGLH---HKPKGK-WYCPKCRG 250
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MLNPANGDPS HAVVNYVEEY LDLVESLPFD LQRSVSLMKE IDAKYQDVLK ELDDAYERYR 60
RESDSLQRRK LQLSIQRALI RSQELGDEKI QIAGQMVELV ENRTRQMDWH SELLLSSQEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAGCAACGCA GCAGGAGCTG CATCACGGAG CGCCGAACCG CCGCTGCAAA AAACACACGC 60
GTTTATTATC CACACCAGGT AAATACATCT GCCAGCCACT TAGTTACCAG CTAGAGAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	59.79	1.00e-88	318.00
IUUC-Apl-003910	Anas platyrhynchos	64.31	2.00e-88	318.00
IUUC-Aca-004874	Anolis carolinensis	61.54	3.00e-87	314.00
IUUC-Ame-011262	Astyanax mexicanus	61.72	2.00e-87	315.00
IUUC-Cja-018925	Callithrix jacchus	61.36	4.00e-88	317.00
IUUC-Cfa-020663	Canis familiaris	58.31	2.00e-84	305.00
IUUC-Csa-023825	Chlorocebus sabaeus	61.69	2.00e-88	318.00
IUUC-Cho-024577	Choloepus hoffmanni	55.65	6.00e-65	240.00
IUUC-Cne-027005	Cryptococcus neoformans	49.25	1.00e-16	80.50
IUUC-Dno-029834	Dasypus novemcinctus	59.44	2.00e-87	315.00
IUUC-Dor-030315	Dipodomys ordii	64.26	8.00e-73	267.00
IUUC-Dse-031323	Dothistroma septosporum	51.35	5.00e-18	86.30
IUUC-Eca-034244	Equus caballus	57.08	8.00e-68	249.00
IUUC-Fca-035391	Felis catus	55.68	1.00e-71	262.00
IUUC-Fal-036838	Ficedula albicollis	65.02	3.00e-89	321.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	90.90
IUUC-Gmo-038557	Gadus morhua	77.86	7.00e-96	343.00
IUUC-Gga-040619	Gallus gallus	59.44	4.00e-88	317.00
IUUC-Ggo-045481	Gorilla gorilla	57.77	3.00e-66	245.00
IUUC-Hsa-046170	Homo sapiens	57.77	2.00e-66	245.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	58.75	1.00e-66	246.00
IUUC-Lch-050397	Latimeria chalumnae	62.37	3.00e-88	318.00
IUUC-Loc-052038	Lepisosteus oculatus	64.73	4.00e-81	294.00
IUUC-Laf-054126	Loxodonta africana	60.14	3.00e-88	317.00
IUUC-Mcc-055031	Macaca mulatta	58.40	6.00e-66	244.00
IUUC-Meu-056248	Macropus eugenii	62.40	3.00e-65	241.00
IUUC-Mga-059217	Meleagris gallopavo	60.17	4.00e-67	247.00
IUUC-Mmr-061581	Microcebus murinus	58.30	7.00e-71	259.00
IUUC-Mdo-062452	Monodelphis domestica	59.12	1.00e-87	316.00
IUUC-Mmu-063412	Mus musculus	64.54	1.00e-86	313.00
IUUC-Mpu-066479	Mustela putorius furo	56.67	4.00e-67	248.00
IUUC-Mlu-067586	Myotis lucifugus	55.59	7.00e-79	286.00
IUUC-Nle-069122	Nomascus leucogenys	61.75	3.00e-88	318.00
IUUC-Opr-070835	Ochotona princeps	61.60	1.00e-63	236.00
IUUC-Ont-071606	Oreochromis niloticus	83.93	2.00e-122	432.00
IUUC-Oan-073023	Ornithorhynchus anatinus	61.89	1.00e-88	319.00
IUUC-Ocu-073779	Oryctolagus cuniculus	61.89	4.00e-66	244.00
IUUC-Ola-086891	Oryzias latipes	86.43	2.00e-124	437.00
IUUC-Oga-087954	Otolemur garnettii	59.09	1.00e-85	309.00
IUUC-Oar-090006	Ovis aries	64.06	1.00e-85	309.00
IUUC-Ptr-090589	Pan troglodytes	61.40	6.00e-88	317.00
IUUC-Pan-091896	Papio anubis	58.80	9.00e-67	247.00
IUUC-Psi-093266	Pelodiscus sinensis	64.31	9.00e-89	319.00
IUUC-Pma-094265	Petromyzon marinus	74.39	2.00e-34	137.00
IUUC-Pfo-097531	Poecilia formosa	77.27	3.00e-127	447.00
IUUC-Pab-098253	Pongo abelii	61.40	1.00e-87	315.00
IUUC-Rno-105964	Rattus norvegicus	52.10	3.00e-45	174.00
IUUC-Sha-107270	Sarcophilus harrisii	64.44	3.00e-88	317.00
IUUC-Tgu-116822	Taeniopygia guttata	64.66	5.00e-89	320.00
IUUC-Tru-118262	Takifugu rubripes	80.46	1.00e-105	376.00
IUUC-Tni-119980	Tetraodon nigroviridis	80.66	3.00e-115	407.00
IUUC-Tre-121950	Trichoderma reesei	64.29	2.00e-19	90.90
IUUC-Ttr-128672	Tursiops truncatus	64.10	1.00e-66	246.00
IUUC-Xtr-132200	Xenopus tropicalis	60.50	2.00e-85	308.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence