iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115560

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU467054

Gene Name

WDR61

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000001757.2	ENSSSCT00000001963.2	ENSSSCP00000001914.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-41	137.9	212	251
UBD/Beta-Prp	3.50e-65	220.4	70	285

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+++v  +af +d t++vs+s D+++kvWD+ t +++++
   Q: 212  GHASWVLNVAFcPDdTHFVSSSSDKSVKVWDVGTRTCVHT 251
           8***********777*****************99999875 PP

UBD/Beta-Prp

   S: 76   ikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlW 164
           +++wdl++gk++ ++ +   ++++l+fsp++++l++G+h+  ++++ +e+g++ +  l+ + +++ +++++pdg++l+sG+ D++++++
   Q: 70   VRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIF 157
           79*****************************************************.********************************* PP
   S: 165  dlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrs 253
           d++tgkll+tl+g h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p+d+++vs ssD+s+++Wd+ +
   Q: 158  DIATGKLLHTLEG-HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGT 245
           ************9.*************************************************************************** PP
   S: 254  gdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwkl 294
           +++++t+  h+++v+ v++ + +++++v++++d++++i+++
   Q: 246  RTCVHTFFDHQDQVWGVKY-NGNGSKIVSVGDDQEIHIYDC 285
           *******************.999****************98 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MTNQYSILFK QEQAHDDAIW SVAWGTNKKE NSETVVTGSL DDLVKVWKWR DEKLDLQWSL 60
EGHQLGVVSV RLWDLENGKQ IKSIDAGPVD AWTLAFSPDS QYLATGTHVG KVNIFGVESG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCCGCGCG CCGAGGTCGC GCGGAGCCGG TCCTCGGAAG AGCTGAGGGG CTGTGCAGCC 60
GGGCAGTGAG GTGAGTTGGT TGGTACAGCC GTTAAGGACC GCAGTCTTCG GTGCCGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	32.44	6.00e-44	171.00
IUUC-Aml-002245	Ailuropoda melanoleuca	92.79	7.00e-155	539.00
IUUC-Atr-003142	Amborella trichopoda	51.55	1.00e-38	152.00
IUUC-Apl-003179	Anas platyrhynchos	85.90	1.00e-145	508.00
IUUC-Aca-004880	Anolis carolinensis	83.93	1.00e-146	512.00
IUUC-Aly-005956	Arabidopsis lyrata	35.58	2.00e-50	192.00
IUUC-Ath-007230	Arabidopsis thaliana	35.58	2.00e-50	192.00
IUUC-Acl-008297	Aspergillus clavatus	31.84	7.00e-24	104.00
IUUC-Ang-009702	Aspergillus niger	31.94	5.00e-28	117.00
IUUC-Ame-011511	Astyanax mexicanus	79.48	1.00e-138	485.00
IUUC-Bgr-012189	Blumeria graminis	34.34	7.00e-26	110.00
IUUC-Bta-012936	Bos taurus	93.77	7.00e-156	542.00
IUUC-Bdi-015020	Brachypodium distachyon	35.17	2.00e-43	169.00
IUUC-Bol-016345	Brassica oleracea	35.90	5.00e-51	194.00
IUUC-Bra-017323	Brassica rapa	35.90	4.00e-51	194.00
IUUC-Cja-019961	Callithrix jacchus	93.44	3.00e-155	540.00
IUUC-Cfa-020862	Canis familiaris	92.46	5.00e-154	536.00
IUUC-Cpo-021356	Cavia porcellus	93.05	1.00e-152	531.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	39.27	3.00e-52	198.00
IUUC-Csa-024067	Chlorocebus sabaeus	93.11	1.00e-154	538.00
IUUC-Cho-024421	Choloepus hoffmanni	83.84	8.00e-83	298.00
IUUC-Cin-025261	Ciona intestinalis	60.66	9.00e-107	379.00
IUUC-Cgl-026446	Colletotrichum gloeosporioides	33.00	4.00e-25	108.00
IUUC-Cne-026846	Cryptococcus neoformans	27.04	2.00e-20	92.80
IUUC-Dre-027706	Danio rerio	61.97	6.00e-101	360.00
IUUC-Dno-029084	Dasypus novemcinctus	93.16	2.00e-154	537.00
IUUC-Dor-030353	Dipodomys ordii	76.45	6.00e-110	389.00
IUUC-Dse-031348	Dothistroma septosporum	32.37	9.00e-25	107.00
IUUC-Dme-031836	Drosophila melanogaster	50.46	7.00e-83	300.00
IUUC-Ete-032261	Echinops telfairi	90.49	4.00e-149	520.00
IUUC-Eca-034231	Equus caballus	85.90	7.00e-140	489.00
IUUC-Eeu-034828	Erinaceus europaeus	91.41	1.00e-143	501.00
IUUC-Fca-036569	Felis catus	93.11	1.00e-154	538.00
IUUC-Fal-037469	Ficedula albicollis	87.87	2.00e-149	521.00
IUUC-Fox-038047	Fusarium oxysporum	31.65	8.00e-25	107.00
IUUC-Gmo-039579	Gadus morhua	79.34	4.00e-136	476.00
IUUC-Gga-040808	Gallus gallus	88.36	8.00e-143	499.00
IUUC-Gac-042100	Gasterosteus aculeatus	79.67	4.00e-137	480.00
IUUC-Gma-043509	Glycine max	39.06	1.00e-54	206.00
IUUC-Ggo-045227	Gorilla gorilla	93.44	3.00e-155	540.00
IUUC-Hsa-045839	Homo sapiens	93.44	3.00e-155	540.00
IUUC-Hvu-047591	Hordeum vulgare	35.76	1.00e-45	176.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	93.77	6.00e-156	542.00
IUUC-Lch-049549	Latimeria chalumnae	79.02	3.00e-136	477.00
IUUC-Lpe-050746	Leersia perrieri	37.30	6.00e-47	180.00
IUUC-Loc-052540	Lepisosteus oculatus	82.30	2.00e-138	484.00
IUUC-Lma-052992	Leptosphaeria maculans	28.95	3.00e-25	108.00
IUUC-Laf-053907	Loxodonta africana	93.77	6.00e-156	542.00
IUUC-Mcc-055828	Macaca mulatta	87.38	4.00e-151	526.00
IUUC-Meu-056075	Macropus eugenii	88.63	3.00e-124	437.00
IUUC-Mor-056971	Magnaporthe oryzae	33.51	3.00e-23	102.00
IUUC-Mtr-057728	Medicago truncatula	37.82	1.00e-50	192.00
IUUC-Mga-059872	Meleagris gallopavo	88.20	4.00e-150	523.00
IUUC-Mvi-060564	Microbotryum violaceum	30.10	1.00e-25	110.00
IUUC-Mmr-060985	Microcebus murinus	90.79	1.00e-147	514.00
IUUC-Mdo-062758	Monodelphis domestica	85.86	5.00e-148	516.00
IUUC-Mmu-063580	Mus musculus	91.48	3.00e-153	533.00
IUUC-Mac-064880	Musa acuminata	37.62	7.00e-52	197.00
IUUC-Mpu-066577	Mustela putorius furo	92.13	3.00e-153	533.00
IUUC-Nle-069573	Nomascus leucogenys	93.44	3.00e-155	540.00
IUUC-Opr-070216	Ochotona princeps	91.69	5.00e-151	526.00
IUUC-Ont-071981	Oreochromis niloticus	80.98	7.00e-140	489.00
IUUC-Oan-073223	Ornithorhynchus anatinus	86.87	4.00e-97	346.00
IUUC-Ocu-074199	Oryctolagus cuniculus	79.02	8.00e-126	442.00
IUUC-Oba-075255	Oryza barthii	40.43	1.00e-41	162.00
IUUC-Obr-076168	Oryza brachyantha	47.20	7.00e-36	143.00
IUUC-Ogl-077777	Oryza glaberrima	37.10	1.00e-47	182.00
IUUC-Ogu-078780	Oryza glumaepatula	37.10	1.00e-47	182.00
IUUC-Oin-079228	Oryza indica	37.10	3.00e-48	184.00
IUUC-Olo-080617	Oryza longistaminata	45.77	2.00e-29	121.00
IUUC-Ome-081421	Oryza meridionalis	37.10	1.00e-44	173.00
IUUC-Oni-082997	Oryza nivara	37.10	3.00e-48	184.00
IUUC-Opu-083931	Oryza punctata	37.42	2.00e-45	176.00
IUUC-Oru-084645	Oryza rufipogon	37.10	1.00e-47	182.00
IUUC-Osa-085842	Oryza sativa	37.10	3.00e-48	184.00
IUUC-Ola-086696	Oryzias latipes	80.33	1.00e-135	475.00
IUUC-Olu-087643	Ostreococcus lucimarinus	39.91	1.00e-41	162.00
IUUC-Oga-088272	Otolemur garnettii	92.76	2.00e-153	534.00
IUUC-Oar-089416	Ovis aries	93.77	7.00e-156	542.00
IUUC-Ptr-090944	Pan troglodytes	93.44	3.00e-155	540.00
IUUC-Pan-091861	Papio anubis	93.44	3.00e-155	540.00
IUUC-Psi-093750	Pelodiscus sinensis	89.18	1.00e-150	525.00
IUUC-Pma-094608	Petromyzon marinus	75.81	1.00e-132	465.00
IUUC-Pno-094832	Phaeosphaeria nodorum	29.70	3.00e-27	115.00
IUUC-Ppa-095737	Physcomitrella patens	38.14	3.00e-51	195.00
IUUC-Pfo-096479	Poecilia formosa	81.64	6.00e-139	486.00
IUUC-Pab-098179	Pongo abelii	93.44	3.00e-155	540.00
IUUC-Pop-099532	Populus trichocarpa	38.46	2.00e-50	192.00
IUUC-Pca-100664	Procavia capensis	69.93	1.00e-92	332.00
IUUC-Ppe-102056	Prunus persica	37.66	2.00e-52	199.00
IUUC-Pva-102859	Pteropus vampyrus	93.11	1.00e-154	538.00
IUUC-Pte-104236	Pyrenophora teres	35.56	2.00e-25	108.00
IUUC-Rno-105826	Rattus norvegicus	91.15	1.00e-152	531.00
IUUC-Sha-106660	Sarcophilus harrisii	88.04	1.00e-147	515.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	32.57	1.00e-32	133.00
IUUC-Spo-108244	Schizosaccharomyces pombe	32.04	2.00e-33	135.00
IUUC-Smo-109234	Selaginella moellendorffii	40.80	5.00e-56	211.00
IUUC-Sit-110048	Setaria italica	35.49	1.00e-39	156.00
IUUC-Sly-111618	Solanum lycopersicum	35.90	5.00e-46	177.00
IUUC-Stu-112543	Solanum tuberosum	36.22	5.00e-49	187.00
IUUC-Sar-113743	Sorex araneus	72.46	1.00e-116	412.00
IUUC-Sbi-114309	Sorghum bicolor	36.52	1.00e-40	159.00
IUUC-Tgu-117300	Taeniopygia guttata	88.20	6.00e-150	523.00
IUUC-Tru-117933	Takifugu rubripes	80.33	5.00e-139	486.00
IUUC-Tsy-119574	Tarsius syrichta	82.95	8.00e-132	462.00
IUUC-Tni-120191	Tetraodon nigroviridis	87.16	3.00e-105	373.00
IUUC-Tca-120983	Theobroma cacao	37.86	5.00e-52	197.00
IUUC-Tae-124056	Triticum aestivum	34.59	4.00e-46	177.00
IUUC-Tur-126711	Triticum urartu	34.48	5.00e-45	174.00
IUUC-Tme-127066	Tuber melanosporum	34.23	7.00e-30	124.00
IUUC-Tbe-127802	Tupaia belangeri	93.11	1.00e-154	538.00
IUUC-Ttr-128861	Tursiops truncatus	92.86	2.00e-53	201.00
IUUC-Vda-129720	Verticillium dahliae	32.27	1.00e-20	93.60
IUUC-Vpa-130618	Vicugna pacos	88.66	8.00e-123	432.00
IUUC-Vvi-130981	Vitis vinifera	38.14	2.00e-50	192.00
IUUC-Xtr-132460	Xenopus tropicalis	81.97	5.00e-137	479.00
IUUC-Xma-134154	Xiphophorus maculatus	81.64	5.00e-139	486.00
IUUC-Zma-135097	Zea mays	36.13	2.00e-34	138.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence