iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106521

Ensembl Protein ID

ENSSHAP00000008920.1

UniProt Accession

G3W0G5; G3W0G5_SARHA

Genbank Protein ID

ENSSHAP00000008920

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01105792

Gene Name

KLHL15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000007725.1	ENSSHAT00000008994.1	ENSSHAP00000008920.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	7.30e-18	64.9	32	96

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lv+++ +f+ahk+ La++S++F+ +f+ +++e++ ++++++k++ ++ f+++l+F+Y g++++
   Q: 32   DVTLVIEDHQFQAHKALLATQSDYFRIMFTADMRERD-QDKIHLKGLTATGFSHVLQFMYYGTIEL 96
           9***********************************9.************************9876 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MAGDVEGFSS SIHDTSVSAG FRALYEEGLL LDVTLVIEDH QFQAHKALLA TQSDYFRIMF 60
TADMRERDQD KIHLKGLTAT GFSHVLQFMY YGTIELSMNT VHEILQAAMY VQLIEVVKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGGGG ACGTGGAAGG GTTTAGTTCC TCCATCCATG ACACCAGTGT CTCTGCTGGG 60
TTCAGAGCAC TGTATGAGGA GGGATTGCTT CTTGATGTCA CACTTGTCAT TGAAGATCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030597--KLHL15
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005634--C:nucleus
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0071630--P:ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001418	Ailuropoda melanoleuca	93.05	0.00e+00	1056.00
IUUC-Apl-003970	Anas platyrhynchos	95.42	0.00e+00	1085.00
IUUC-Aca-005217	Anolis carolinensis	94.75	0.00e+00	1078.00
IUUC-Ame-011065	Astyanax mexicanus	85.54	0.00e+00	1028.00
IUUC-Bta-012443	Bos taurus	92.20	0.00e+00	1050.00
IUUC-Cja-019831	Callithrix jacchus	92.88	0.00e+00	1054.00
IUUC-Cfa-020941	Canis familiaris	93.22	0.00e+00	1057.00
IUUC-Cpo-021730	Cavia porcellus	92.71	0.00e+00	1055.00
IUUC-Csa-023247	Chlorocebus sabaeus	92.71	0.00e+00	1052.00
IUUC-Dre-028474	Danio rerio	84.92	0.00e+00	1023.00
IUUC-Dno-029411	Dasypus novemcinctus	93.22	0.00e+00	1057.00
IUUC-Dor-030576	Dipodomys ordii	92.54	0.00e+00	1053.00
IUUC-Ete-032327	Echinops telfairi	90.00	0.00e+00	1011.00
IUUC-Eca-033477	Equus caballus	93.05	0.00e+00	1057.00
IUUC-Fca-035546	Felis catus	93.05	0.00e+00	1057.00
IUUC-Fal-037370	Ficedula albicollis	95.42	0.00e+00	1085.00
IUUC-Gmo-038961	Gadus morhua	83.19	0.00e+00	965.00
IUUC-Gga-041049	Gallus gallus	95.42	0.00e+00	1085.00
IUUC-Gac-042003	Gasterosteus aculeatus	82.35	0.00e+00	961.00
IUUC-Ggo-044451	Gorilla gorilla	92.71	0.00e+00	1052.00
IUUC-Hsa-045874	Homo sapiens	92.71	0.00e+00	1053.00
IUUC-Itr-048357	Ictidomys tridecemlineatus	92.88	0.00e+00	1055.00
IUUC-Lch-049603	Latimeria chalumnae	90.68	1.00e-127	448.00
IUUC-Loc-052300	Lepisosteus oculatus	88.98	0.00e+00	1058.00
IUUC-Laf-054459	Loxodonta africana	93.39	0.00e+00	1058.00
IUUC-Mcc-054846	Macaca mulatta	92.71	0.00e+00	1052.00
IUUC-Meu-056797	Macropus eugenii	100.00	7.00e-117	414.00
IUUC-Mga-059446	Meleagris gallopavo	95.42	0.00e+00	1085.00
IUUC-Mmr-061125	Microcebus murinus	91.86	0.00e+00	1046.00
IUUC-Mdo-062947	Monodelphis domestica	99.30	0.00e+00	1103.00
IUUC-Mmu-063708	Mus musculus	93.22	0.00e+00	1057.00
IUUC-Mpu-066447	Mustela putorius furo	93.22	0.00e+00	1058.00
IUUC-Mlu-066999	Myotis lucifugus	88.21	0.00e+00	919.00
IUUC-Nle-069918	Nomascus leucogenys	92.71	0.00e+00	1052.00
IUUC-Ont-071446	Oreochromis niloticus	85.89	0.00e+00	979.00
IUUC-Oan-072872	Ornithorhynchus anatinus	90.85	0.00e+00	1103.00
IUUC-Ocu-073969	Oryctolagus cuniculus	92.64	0.00e+00	844.00
IUUC-Ola-087557	Oryzias latipes	82.32	4.00e-150	523.00
IUUC-Oga-088567	Otolemur garnettii	92.88	0.00e+00	1053.00
IUUC-Oar-089882	Ovis aries	92.20	0.00e+00	1050.00
IUUC-Ptr-091229	Pan troglodytes	92.70	0.00e+00	1026.00
IUUC-Pan-091977	Papio anubis	92.71	0.00e+00	1052.00
IUUC-Psi-093496	Pelodiscus sinensis	97.62	4.00e-159	554.00
IUUC-Pfo-096759	Poecilia formosa	81.83	0.00e+00	959.00
IUUC-Pab-098480	Pongo abelii	92.71	0.00e+00	1052.00
IUUC-Rno-105500	Rattus norvegicus	93.22	0.00e+00	1057.00
IUUC-Ssc-116372	Sus scrofa	92.71	0.00e+00	1053.00
IUUC-Tgu-116481	Taeniopygia guttata	95.42	0.00e+00	1085.00
IUUC-Tru-118542	Takifugu rubripes	80.20	0.00e+00	948.00
IUUC-Tsy-118848	Tarsius syrichta	86.81	3.00e-114	405.00
IUUC-Tni-119989	Tetraodon nigroviridis	83.57	0.00e+00	929.00
IUUC-Tbe-127485	Tupaia belangeri	93.05	0.00e+00	1055.00
IUUC-Ttr-129214	Tursiops truncatus	92.37	0.00e+00	1048.00
IUUC-Vpa-130261	Vicugna pacos	90.00	0.00e+00	1013.00
IUUC-Xtr-132092	Xenopus tropicalis	93.35	0.00e+00	1031.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence