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Tag Content
iUUCD ID IUUC-Csa-023304
Ensembl Protein ID ENSCSAP00000015014.1
UniProt Accession A0A0D9S2C5; A0A0D9S2C5_CHLSB
Genbank Protein ID ENSCSAP00000015014
Protein Name Inhibitor of growth protein
Genbank Nucleotide ID AQIB01017943
Gene Name ING2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCSAG00000003025.1 ENSCSAT00000001056.1 ENSCSAP00000015014.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 3.10e-09 36.8 213 259
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
    ++C +C + + +e ++ C++ C ewfH+ C++l+ +p+ + w+CpkCr
   Q: 213 TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVSLT---YKPKGK-WYCPKCR 259
    69*.*******99..*****999*99***********...888886.******8 PP
   

Organism Chlorocebus sabaeus
Protein Sequence
(Fasta)
MLGQQQQQLY SSAALLTGER SRLLTCYVQD YLECVESLPH DMQRNVSVLR ELDNKYQETL 60
KEIDDVYEKY KKEDDLNQKK RLQQLLQRAL INSQELGDEK IQIVTQMLEL VENRARQMEL 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Csa-023304|E3,PHD|Chlorocebus sabaeus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGCCGGTGTG GCCGGGCGGA GCTGCCCCTT CCCGCGGGGA GGGCGGCCGG AAGGACCGAG 60
CCGCCTCCCC TGCCGGGTCC CATTCAGACG CGGGGCGCAG AGACTGGCTC CCCAGGCTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Csa-023304|E3,PHD|Chlorocebus sabaeus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0016602--C:CCAAT-binding factor complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005886--C:plasma membrane
GO:0016580--C:Sin3 complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0035091--F:phosphatidylinositol binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0030317--P:flagellated sperm motility
GO:0048133--P:male germ-line stem cell asymmetric division
GO:0007141--P:male meiosis I
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0031065--P:positive regulation of histone deacetylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:2000772--P:regulation of cellular senescence
GO:0072520--P:seminiferous tubule development
GO:0007286--P:spermatid development

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002213 Ailuropoda melanoleuca 97.86 4.00e-120 423.00
IUUC-Apl-003705 Anas platyrhynchos 88.79 5.00e-91 326.00
IUUC-Aca-004990 Anolis carolinensis 81.47 6.00e-98 350.00
IUUC-Ame-011426 Astyanax mexicanus 71.17 3.00e-84 304.00
IUUC-Bta-012721 Bos taurus 98.16 4.00e-119 420.00
IUUC-Cja-018960 Callithrix jacchus 99.24 8.00e-108 382.00
IUUC-Cfa-020869 Canis familiaris 97.50 1.00e-119 422.00
IUUC-Cpo-021414 Cavia porcellus 96.07 5.00e-118 416.00
IUUC-Dre-028562 Danio rerio 69.96 3.00e-88 318.00
IUUC-Dno-029945 Dasypus novemcinctus 97.73 2.00e-114 405.00
IUUC-Dor-030141 Dipodomys ordii 96.43 5.00e-117 413.00
IUUC-Ete-032709 Echinops telfairi 95.76 5.00e-128 449.00
IUUC-Eca-033432 Equus caballus 98.53 5.00e-119 420.00
IUUC-Eeu-035285 Erinaceus europaeus 98.04 1.00e-89 322.00
IUUC-Fca-036467 Felis catus 98.11 4.00e-114 404.00
IUUC-Fal-036700 Ficedula albicollis 87.56 3.00e-90 323.00
IUUC-Gmo-038748 Gadus morhua 63.41 3.00e-85 308.00
IUUC-Gga-040175 Gallus gallus 88.34 8.00e-91 326.00
IUUC-Gac-041403 Gasterosteus aculeatus 64.23 2.00e-89 322.00
IUUC-Hsa-045837 Homo sapiens 100.00 3.00e-115 407.00
IUUC-Itr-049062 Ictidomys tridecemlineatus 97.86 6.00e-120 423.00
IUUC-Lch-049965 Latimeria chalumnae 80.92 2.00e-99 355.00
IUUC-Laf-053353 Loxodonta africana 96.89 2.00e-100 357.00
IUUC-Mcc-055155 Macaca mulatta 100.00 2.00e-74 271.00
IUUC-Meu-056470 Macropus eugenii 94.09 1.00e-111 395.00
IUUC-Mga-059570 Meleagris gallopavo 88.34 5.00e-90 323.00
IUUC-Mmr-061385 Microcebus murinus 99.64 1.00e-114 405.00
IUUC-Mdo-062144 Monodelphis domestica 94.14 5.00e-113 400.00
IUUC-Mmu-063215 Mus musculus 96.44 3.00e-118 417.00
IUUC-Mpu-065749 Mustela putorius furo 97.07 6.00e-98 349.00
IUUC-Mlu-067245 Myotis lucifugus 75.49 2.00e-81 294.00
IUUC-Nle-069968 Nomascus leucogenys 99.47 4.00e-83 300.00
IUUC-Ont-071524 Oreochromis niloticus 66.30 1.00e-86 313.00
IUUC-Ocu-074870 Oryctolagus cuniculus 97.53 2.00e-119 421.00
IUUC-Ola-087400 Oryzias latipes 89.02 2.00e-44 172.00
IUUC-Oga-088336 Otolemur garnettii 98.23 2.00e-112 398.00
IUUC-Oar-090136 Ovis aries 97.78 1.00e-117 415.00
IUUC-Ptr-091348 Pan troglodytes 100.00 8.00e-84 303.00
IUUC-Pan-092819 Papio anubis 100.00 3.00e-115 407.00
IUUC-Psi-093854 Pelodiscus sinensis 86.21 6.00e-63 233.00
IUUC-Pfo-096633 Poecilia formosa 63.79 1.00e-80 293.00
IUUC-Pab-098346 Pongo abelii 99.64 9.00e-115 405.00
IUUC-Pca-100278 Procavia capensis 95.67 1.00e-116 412.00
IUUC-Pva-103190 Pteropus vampyrus 98.86 2.00e-115 407.00
IUUC-Rno-104940 Rattus norvegicus 96.59 8.00e-113 399.00
IUUC-Sha-107533 Sarcophilus harrisii 92.28 5.00e-114 403.00
IUUC-Sar-113630 Sorex araneus 96.08 1.00e-88 319.00
IUUC-Ssc-115734 Sus scrofa 98.86 3.00e-115 407.00
IUUC-Tgu-117034 Taeniopygia guttata 88.00 1.00e-90 325.00
IUUC-Tru-118168 Takifugu rubripes 60.34 1.00e-81 296.00
IUUC-Tsy-119494 Tarsius syrichta 99.51 2.00e-83 301.00
IUUC-Tni-120100 Tetraodon nigroviridis 61.25 3.00e-77 281.00
IUUC-Ttr-128442 Tursiops truncatus 98.53 5.00e-90 323.00
IUUC-Vpa-130063 Vicugna pacos 97.50 1.00e-119 422.00
IUUC-Xtr-132348 Xenopus tropicalis 70.36 1.00e-68 253.00
Created Date 25-Jun-2017

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