iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021934

Ensembl Protein ID

ENSCPOP00000009683.2

UniProt Accession

H0VHP2; H0VHP2_CAVPO

Genbank Protein ID

ENSCPOP00000009683

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02049594

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000010784.3	ENSCPOT00000010882.2	ENSCPOP00000009683.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-34	116.5	180	217
UBD/Beta-Prp	4.90e-55	186.8	282	539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 180  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 217
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++++++++dgt+  w+++ ++l      l+  ++  ++v+ ++  fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s+
   Q: 282  QRYMVSTGADGTVCFWQWDLQSLkfsprpLKFTEKPRPGVQMLCssFSVGGMFLATGSTDHVIRMYflGFEAPEKIAELESHTDKVDSI 370
           689********************99988777778888888755522888888**************99999****************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +f+ +gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ 
   Q: 371  QFCNTGDRFLSGSRDGTARIWRFEQLEWRSIlldmatrisgessseEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHN 459
           *************************999988999********999877788889*********************************** PP
   S: 175  ltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l g h d v  l+   fds  + ++s+++dg++ +wd+ +g  ++ + +         v + +fs+++++++++ s+g + i+
   Q: 460  LLG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGAKLKHYFNIIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 539
           **9.*********555555..99****************998855554432233345666789999***99999999998886 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

SPARRPVPLI ESELYFLIAR YLSAGPCRRA AQVLVQELEQ YQLLPKRLDW EGNEHSRSYE 60
ELVLSNKHVA PDHLLQICQR IGPMLDKEIP PSISRVTSLL GAGRQSLLRT AKDCRHTVWK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGCCCGCCC GACGCCCGGT GCCCCTCATC GAGTCGGGTA AGCCGGGGAC GCGCCGCCCC 60
TCTCCGCGGG CCCGTCGCGT CCTGTCCGTC CCTGCCCCCC CGTCCTGACC TATTCTACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	30.81	4.00e-63	237.00
IUUC-Aml-002332	Ailuropoda melanoleuca	85.33	0.00e+00	2974.00
IUUC-Atr-002600	Amborella trichopoda	29.20	4.00e-68	254.00
IUUC-Apl-004083	Anas platyrhynchos	57.30	0.00e+00	2077.00
IUUC-Aca-004348	Anolis carolinensis	60.65	0.00e+00	1986.00
IUUC-Aly-006517	Arabidopsis lyrata	30.28	7.00e-73	269.00
IUUC-Ath-006577	Arabidopsis thaliana	30.13	5.00e-72	266.00
IUUC-Ame-010718	Astyanax mexicanus	71.85	0.00e+00	1160.00
IUUC-Bta-013217	Bos taurus	81.49	0.00e+00	3476.00
IUUC-Bdi-014797	Brachypodium distachyon	29.69	4.00e-60	227.00
IUUC-Bol-015737	Brassica oleracea	29.55	3.00e-72	267.00
IUUC-Bra-017829	Brassica rapa	29.66	2.00e-72	268.00
IUUC-Cja-019966	Callithrix jacchus	82.19	0.00e+00	3491.00
IUUC-Cfa-021037	Canis familiaris	82.44	0.00e+00	3419.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	34.49	4.00e-35	143.00
IUUC-Csa-023352	Chlorocebus sabaeus	81.20	0.00e+00	3232.00
IUUC-Cho-024690	Choloepus hoffmanni	70.89	0.00e+00	1174.00
IUUC-Cin-025553	Ciona intestinalis	39.15	6.00e-111	395.00
IUUC-Csv-025813	Ciona savignyi	43.02	1.00e-177	616.00
IUUC-Dre-028205	Danio rerio	70.05	0.00e+00	1137.00
IUUC-Dno-028938	Dasypus novemcinctus	78.14	0.00e+00	3333.00
IUUC-Dme-031752	Drosophila melanogaster	49.84	0.00e+00	667.00
IUUC-Eca-034349	Equus caballus	82.61	0.00e+00	3335.00
IUUC-Fca-035485	Felis catus	83.51	0.00e+00	2961.00
IUUC-Fal-037307	Ficedula albicollis	69.56	0.00e+00	2388.00
IUUC-Gga-040865	Gallus gallus	76.13	0.00e+00	2284.00
IUUC-Gma-043340	Glycine max	30.51	3.00e-70	261.00
IUUC-Ggo-045500	Gorilla gorilla	82.21	0.00e+00	3482.00
IUUC-Hsa-046350	Homo sapiens	82.69	0.00e+00	3502.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	90.32	0.00e+00	1168.00
IUUC-Lch-049662	Latimeria chalumnae	65.10	0.00e+00	2069.00
IUUC-Lpe-051619	Leersia perrieri	31.14	5.00e-70	260.00
IUUC-Loc-052853	Lepisosteus oculatus	67.00	0.00e+00	1857.00
IUUC-Laf-053848	Loxodonta africana	80.54	0.00e+00	3318.00
IUUC-Mcc-054638	Macaca mulatta	82.59	0.00e+00	3479.00
IUUC-Meu-056739	Macropus eugenii	79.33	0.00e+00	1095.00
IUUC-Mtr-058094	Medicago truncatula	30.09	2.00e-71	265.00
IUUC-Mga-060165	Meleagris gallopavo	76.31	0.00e+00	2267.00
IUUC-Mmr-061227	Microcebus murinus	83.59	0.00e+00	3534.00
IUUC-Mdo-062074	Monodelphis domestica	68.04	0.00e+00	2718.00
IUUC-Mmu-064075	Mus musculus	81.14	0.00e+00	2957.00
IUUC-Mac-065343	Musa acuminata	30.81	8.00e-76	279.00
IUUC-Mpu-066643	Mustela putorius furo	85.81	0.00e+00	2895.00
IUUC-Mlu-067735	Myotis lucifugus	80.51	0.00e+00	3303.00
IUUC-Nle-069402	Nomascus leucogenys	86.55	0.00e+00	2901.00
IUUC-Ont-072298	Oreochromis niloticus	63.30	0.00e+00	1831.00
IUUC-Oan-072954	Ornithorhynchus anatinus	67.05	0.00e+00	2789.00
IUUC-Ocu-074456	Oryctolagus cuniculus	81.83	0.00e+00	3456.00
IUUC-Oba-075709	Oryza barthii	30.32	2.00e-60	228.00
IUUC-Obr-076619	Oryza brachyantha	31.20	8.00e-71	263.00
IUUC-Ogl-077493	Oryza glaberrima	27.29	9.00e-30	126.00
IUUC-Opu-083233	Oryza punctata	30.61	4.00e-65	244.00
IUUC-Oru-085195	Oryza rufipogon	30.32	2.00e-60	228.00
IUUC-Ola-086648	Oryzias latipes	58.41	0.00e+00	1641.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.38	2.00e-55	211.00
IUUC-Oga-087938	Otolemur garnettii	75.79	0.00e+00	3030.00
IUUC-Oar-090214	Ovis aries	80.53	0.00e+00	3330.00
IUUC-Ptr-091213	Pan troglodytes	82.65	0.00e+00	3463.00
IUUC-Pan-092444	Papio anubis	82.67	0.00e+00	3462.00
IUUC-Psi-093271	Pelodiscus sinensis	64.42	0.00e+00	2152.00
IUUC-Pma-094427	Petromyzon marinus	66.98	2.00e-130	458.00
IUUC-Ppa-095793	Physcomitrella patens	29.17	2.00e-74	275.00
IUUC-Pfo-097318	Poecilia formosa	63.53	0.00e+00	1786.00
IUUC-Pab-097573	Pongo abelii	81.68	0.00e+00	3376.00
IUUC-Pop-099672	Populus trichocarpa	30.92	2.00e-71	265.00
IUUC-Pca-100759	Procavia capensis	69.06	0.00e+00	1113.00
IUUC-Ppe-101849	Prunus persica	29.96	5.00e-75	276.00
IUUC-Pva-102782	Pteropus vampyrus	80.75	0.00e+00	3336.00
IUUC-Rno-105687	Rattus norvegicus	76.03	0.00e+00	3197.00
IUUC-Sha-106680	Sarcophilus harrisii	69.13	0.00e+00	2753.00
IUUC-Sit-110017	Setaria italica	29.38	4.00e-56	214.00
IUUC-Sly-111348	Solanum lycopersicum	30.70	6.00e-75	276.00
IUUC-Sar-113519	Sorex araneus	76.76	0.00e+00	1743.00
IUUC-Sbi-114195	Sorghum bicolor	28.94	1.00e-57	218.00
IUUC-Tgu-116513	Taeniopygia guttata	76.49	0.00e+00	2285.00
IUUC-Tsy-118921	Tarsius syrichta	85.34	0.00e+00	1977.00
IUUC-Tni-120656	Tetraodon nigroviridis	58.74	0.00e+00	1634.00
IUUC-Tca-121615	Theobroma cacao	29.90	6.00e-67	250.00
IUUC-Tae-125478	Triticum aestivum	30.40	1.00e-72	268.00
IUUC-Tur-126809	Triticum urartu	30.37	6.00e-70	260.00
IUUC-Tbe-127663	Tupaia belangeri	71.49	0.00e+00	1179.00
IUUC-Ttr-128561	Tursiops truncatus	79.08	0.00e+00	3210.00
IUUC-Vpa-130444	Vicugna pacos	78.12	0.00e+00	3105.00
IUUC-Vvi-131362	Vitis vinifera	30.77	2.00e-73	271.00
IUUC-Xma-133633	Xiphophorus maculatus	65.37	0.00e+00	1129.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence