iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067431

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02016539

Gene Name

RABGEF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000000605.2	ENSMLUT00000000608.2	ENSMLUP00000000550.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/ZnF_A20	9.90e-19	67.1	25	59

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/ZnF_A20

   S: 1    dpskllCkkgCgfYGnpetngyCSkCyreelrrrr 35
           d+s+llCkkgCg+YGnp+++g+CSkC+ree++++r
   Q: 25   DQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKAR 59
           79*******************************86 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

HFLVCYLINR KKMSLKSERR GIHVDQSELL CKKGCGYYGN PAWQGFCSKC WREEYHKARQ 60
KQIQEDWELA ERLQREEEEA FASSQTSQGA QSLTFSKFEE KKTNEKTRKV TTVKKFFSAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTTTCTTG TTTGTTATTT GATTAACAGG AAGAAAATGA GCCTTAAGTC TGAACGCCGA 60
GGAATTCACG TGGATCAATC AGAGCTCCTT TGCAAGAAAG GATGTGGTTA CTACGGCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003123--VPS9
IPR002653--Znf_A20

PROSITE

PS51205--VPS9
PS51036--ZF_A20

Pfam

PF02204--VPS9
PF01754--zf-A20

SMART

SM00167--VPS9
SM00259--ZnF_A20

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005730--C:nucleolus
GO:0003677--F:DNA binding
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0050728--P:negative regulation of inflammatory response
GO:1900165--P:negative regulation of interleukin-6 secretion
GO:1900235--P:negative regulation of Kit signaling pathway
GO:0002686--P:negative regulation of leukocyte migration
GO:0043305--P:negative regulation of mast cell degranulation
GO:0001933--P:negative regulation of protein phosphorylation
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0048261--P:negative regulation of receptor-mediated endocytosis
GO:0006612--P:protein targeting to membrane
GO:0060368--P:regulation of Fc receptor mediated stimulatory signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000198	Aegilops tauschii	32.88	2.00e-21	97.10
IUUC-Aml-001771	Ailuropoda melanoleuca	83.25	0.00e+00	710.00
IUUC-Atr-003154	Amborella trichopoda	37.29	2.00e-23	103.00
IUUC-Apl-004018	Anas platyrhynchos	88.24	0.00e+00	820.00
IUUC-Aca-005227	Anolis carolinensis	23.08	4.00e-09	57.00
IUUC-Aly-006138	Arabidopsis lyrata	35.45	1.00e-24	107.00
IUUC-Ath-006747	Arabidopsis thaliana	34.92	3.00e-24	106.00
IUUC-Ago-007776	Ashbya gossypii	28.87	1.00e-23	103.00
IUUC-Acl-008235	Aspergillus clavatus	37.99	1.00e-26	115.00
IUUC-Afl-008570	Aspergillus flavus	39.38	3.00e-29	123.00
IUUC-Afu-008815	Aspergillus fumigatus	37.99	5.00e-27	116.00
IUUC-Ani-009381	Aspergillus nidulans	37.50	2.00e-27	117.00
IUUC-Ang-009615	Aspergillus niger	33.64	6.00e-29	122.00
IUUC-Aor-010195	Aspergillus oryzae	39.38	1.00e-29	124.00
IUUC-Ate-010514	Aspergillus terreus	39.11	4.00e-28	119.00
IUUC-Ame-011365	Astyanax mexicanus	64.43	0.00e+00	643.00
IUUC-Bgr-012102	Blumeria graminis	28.17	2.00e-27	117.00
IUUC-Bta-013124	Bos taurus	93.50	0.00e+00	843.00
IUUC-Bci-013943	Botrytis cinerea	40.99	1.00e-27	118.00
IUUC-Bdi-014539	Brachypodium distachyon	34.84	7.00e-27	115.00
IUUC-Bol-016580	Brassica oleracea	37.57	4.00e-29	122.00
IUUC-Bra-017843	Brassica rapa	37.04	8.00e-29	121.00
IUUC-Cel-018199	Caenorhabditis elegans	34.36	5.00e-58	218.00
IUUC-Cja-019941	Callithrix jacchus	91.97	0.00e+00	839.00
IUUC-Cfa-020845	Canis familiaris	93.26	0.00e+00	776.00
IUUC-Cpo-022037	Cavia porcellus	91.67	0.00e+00	823.00
IUUC-Cre-022696	Chlamydomonas reinhardtii	32.99	5.00e-22	99.00
IUUC-Csa-023495	Chlorocebus sabaeus	92.12	0.00e+00	839.00
IUUC-Cho-025076	Choloepus hoffmanni	81.10	0.00e+00	691.00
IUUC-Cin-025400	Ciona intestinalis	43.76	2.00e-111	395.00
IUUC-Csv-025941	Ciona savignyi	38.10	3.00e-84	305.00
IUUC-Cgl-026725	Colletotrichum gloeosporioides	37.89	3.00e-25	110.00
IUUC-Cne-027057	Cryptococcus neoformans	36.90	5.00e-31	129.00
IUUC-Dre-028484	Danio rerio	68.58	0.00e+00	645.00
IUUC-Dno-028906	Dasypus novemcinctus	93.09	0.00e+00	831.00
IUUC-Dor-030124	Dipodomys ordii	81.67	0.00e+00	699.00
IUUC-Dse-031437	Dothistroma septosporum	26.76	7.00e-24	105.00
IUUC-Dme-031696	Drosophila melanogaster	32.78	8.00e-69	254.00
IUUC-Ete-032573	Echinops telfairi	86.67	0.00e+00	671.00
IUUC-Eca-033711	Equus caballus	93.90	0.00e+00	855.00
IUUC-Eeu-034459	Erinaceus europaeus	97.73	2.00e-73	270.00
IUUC-Fca-035447	Felis catus	92.28	0.00e+00	852.00
IUUC-Fal-036605	Ficedula albicollis	84.60	0.00e+00	760.00
IUUC-Fox-037967	Fusarium oxysporum	48.68	3.00e-17	84.00
IUUC-Fso-038110	Fusarium solani	29.07	2.00e-27	117.00
IUUC-Gmo-038785	Gadus morhua	64.89	0.00e+00	649.00
IUUC-Ggr-039760	Gaeumannomyces graminis	39.35	8.00e-27	115.00
IUUC-Gga-040584	Gallus gallus	88.82	0.00e+00	830.00
IUUC-Gac-042469	Gasterosteus aculeatus	62.98	2.00e-162	565.00
IUUC-Gma-044237	Glycine max	37.43	3.00e-26	113.00
IUUC-Ggo-044498	Gorilla gorilla	79.67	0.00e+00	690.00
IUUC-Hsa-046625	Homo sapiens	91.97	0.00e+00	840.00
IUUC-Hvu-047155	Hordeum vulgare	38.89	4.00e-27	115.00
IUUC-Itr-048753	Ictidomys tridecemlineatus	91.87	0.00e+00	833.00
IUUC-Kpa-049160	Komagataella pastoris	31.73	3.00e-22	99.80
IUUC-Lch-050529	Latimeria chalumnae	76.82	0.00e+00	832.00
IUUC-Lpe-051024	Leersia perrieri	34.84	5.00e-29	122.00
IUUC-Loc-052644	Lepisosteus oculatus	68.34	0.00e+00	647.00
IUUC-Lma-053102	Leptosphaeria maculans	35.50	9.00e-25	108.00
IUUC-Laf-054337	Loxodonta africana	90.45	0.00e+00	837.00
IUUC-Mcc-055659	Macaca mulatta	90.91	3.00e-164	571.00
IUUC-Meu-056084	Macropus eugenii	74.66	1.00e-91	330.00
IUUC-Mor-057255	Magnaporthe oryzae	37.42	5.00e-25	109.00
IUUC-Mpo-057454	Magnaporthe poae	39.35	2.00e-27	117.00
IUUC-Mtr-058098	Medicago truncatula	37.17	2.00e-29	123.00
IUUC-Mla-059068	Melampsora laricipopulina	35.87	6.00e-30	125.00
IUUC-Mga-059624	Meleagris gallopavo	75.60	0.00e+00	818.00
IUUC-Mvi-060282	Microbotryum violaceum	30.86	1.00e-23	105.00
IUUC-Mmr-061142	Microcebus murinus	92.38	0.00e+00	869.00
IUUC-Mdo-062289	Monodelphis domestica	88.82	0.00e+00	850.00
IUUC-Mmu-063961	Mus musculus	91.46	0.00e+00	823.00
IUUC-Mac-065188	Musa acuminata	36.87	7.00e-23	101.00
IUUC-Mpu-066291	Mustela putorius furo	91.87	0.00e+00	854.00
IUUC-Nfi-068422	Neosartorya fischeri	37.31	5.00e-28	119.00
IUUC-Ncr-068843	Neurospora crassa	37.65	3.00e-27	117.00
IUUC-Nle-069079	Nomascus leucogenys	91.87	0.00e+00	827.00
IUUC-Opr-070790	Ochotona princeps	92.59	4.00e-55	209.00
IUUC-Ont-071789	Oreochromis niloticus	66.74	5.00e-171	593.00
IUUC-Oan-072946	Ornithorhynchus anatinus	86.61	0.00e+00	790.00
IUUC-Ocu-073816	Oryctolagus cuniculus	93.12	0.00e+00	844.00
IUUC-Oba-075738	Oryza barthii	33.33	9.00e-18	84.70
IUUC-Obr-076355	Oryza brachyantha	38.46	9.00e-28	117.00
IUUC-Ogl-077592	Oryza glaberrima	34.92	3.00e-27	115.00
IUUC-Ogu-078197	Oryza glumaepatula	34.92	4.00e-27	115.00
IUUC-Oin-080047	Oryza indica	37.78	5.00e-26	112.00
IUUC-Olo-080317	Oryza longistaminata	34.92	6.00e-27	114.00
IUUC-Ome-081589	Oryza meridionalis	37.78	2.00e-26	114.00
IUUC-Oni-082700	Oryza nivara	33.33	8.00e-18	85.10
IUUC-Opu-083923	Oryza punctata	34.97	5.00e-22	98.20
IUUC-Oru-084318	Oryza rufipogon	33.33	8.00e-18	85.10
IUUC-Osa-086246	Oryza sativa	40.68	1.00e-06	43.90
IUUC-Ola-086730	Oryzias latipes	56.63	8.00e-146	510.00
IUUC-Olu-087719	Ostreococcus lucimarinus	34.64	1.00e-23	103.00
IUUC-Oga-088992	Otolemur garnettii	80.28	0.00e+00	866.00
IUUC-Oar-089789	Ovis aries	92.84	0.00e+00	857.00
IUUC-Ptr-091636	Pan troglodytes	92.48	0.00e+00	831.00
IUUC-Pan-092911	Papio anubis	91.27	0.00e+00	845.00
IUUC-Psi-093194	Pelodiscus sinensis	76.82	0.00e+00	826.00
IUUC-Pma-094212	Petromyzon marinus	46.59	6.00e-109	387.00
IUUC-Pno-094831	Phaeosphaeria nodorum	33.33	2.00e-25	111.00
IUUC-Ppa-095705	Physcomitrella patens	34.92	2.00e-29	124.00
IUUC-Pfo-096694	Poecilia formosa	63.12	1.00e-170	592.00
IUUC-Pab-097706	Pongo abelii	92.14	0.00e+00	835.00
IUUC-Pop-099891	Populus trichocarpa	37.43	7.00e-26	112.00
IUUC-Pca-100879	Procavia capensis	84.11	2.00e-84	305.00
IUUC-Ppe-101334	Prunus persica	35.45	5.00e-26	112.00
IUUC-Pva-103225	Pteropus vampyrus	77.82	0.00e+00	668.00
IUUC-Pgr-103564	Puccinia graminis	30.57	2.00e-29	124.00
IUUC-Ptt-103802	Puccinia triticina	45.13	5.00e-24	105.00
IUUC-Pte-104345	Pyrenophora teres	34.50	2.00e-25	110.00
IUUC-Pyt-104716	Pyrenophora triticirepentis	34.30	3.00e-26	114.00
IUUC-Rno-106101	Rattus norvegicus	90.96	0.00e+00	830.00
IUUC-Sce-106460	Saccharomyces cerevisiae	30.38	5.00e-24	105.00
IUUC-Sha-106919	Sarcophilus harrisii	76.57	0.00e+00	808.00
IUUC-Sja-107880	Schizosaccharomyces japonicus	37.57	5.00e-29	122.00
IUUC-Spo-108087	Schizosaccharomyces pombe	32.46	9.00e-26	111.00
IUUC-Ssl-108614	Sclerotinia sclerotiorum	29.82	2.00e-07	51.20
IUUC-Smo-108740	Selaginella moellendorffii	37.14	2.00e-28	120.00
IUUC-Sit-110678	Setaria italica	35.64	4.00e-27	115.00
IUUC-Sly-111526	Solanum lycopersicum	38.98	3.00e-26	112.00
IUUC-Stu-112494	Solanum tuberosum	39.55	8.00e-27	115.00
IUUC-Sar-112929	Sorex araneus	97.45	3.00e-162	565.00
IUUC-Sbi-114242	Sorghum bicolor	36.65	1.00e-27	117.00
IUUC-Sre-115224	Sporisorium reilianum	36.84	2.00e-27	117.00
IUUC-Ssc-115239	Sus scrofa	93.90	0.00e+00	850.00
IUUC-Tgu-117499	Taeniopygia guttata	85.98	0.00e+00	798.00
IUUC-Tru-118450	Takifugu rubripes	56.39	7.00e-165	573.00
IUUC-Tsy-119462	Tarsius syrichta	92.24	0.00e+00	830.00
IUUC-Tni-120855	Tetraodon nigroviridis	58.57	3.00e-167	581.00
IUUC-Tca-121213	Theobroma cacao	35.45	6.00e-25	108.00
IUUC-Tre-122186	Trichoderma reesei	37.10	5.00e-27	115.00
IUUC-Tvi-122541	Trichoderma virens	33.48	2.00e-27	117.00
IUUC-Tae-123631	Triticum aestivum	40.00	1.00e-27	117.00
IUUC-Tur-126572	Triticum urartu	40.00	2.00e-27	117.00
IUUC-Tme-127023	Tuber melanosporum	31.80	1.00e-29	124.00
IUUC-Tbe-127453	Tupaia belangeri	91.71	0.00e+00	727.00
IUUC-Ttr-128526	Tursiops truncatus	93.09	0.00e+00	838.00
IUUC-Uma-129660	Ustilago maydis	36.51	3.00e-27	117.00
IUUC-Vda-129737	Verticillium dahliae	36.05	2.00e-22	100.00
IUUC-Vpa-130505	Vicugna pacos	85.49	0.00e+00	664.00
IUUC-Vvi-131088	Vitis vinifera	37.08	9.00e-24	104.00
IUUC-Xtr-132799	Xenopus tropicalis	77.58	0.00e+00	721.00
IUUC-Xma-133345	Xiphophorus maculatus	63.73	2.00e-166	578.00
IUUC-Yli-134416	Yarrowia lipolytica	31.73	3.00e-29	123.00
IUUC-Zma-134750	Zea mays	37.78	2.00e-26	113.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence