iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066016

Ensembl Protein ID

ENSMPUP00000012340.1

UniProt Accession

M3YLY3; M3YLY3_MUSPF

Genbank Protein ID

ENSMPUP00000012340

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01094297

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000012434.1	ENSMPUT00000012541.1	ENSMPUP00000012340.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-41	138.6	508	544
UBD/Beta-Prp	1.60e-69	234.3	271	570

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gHtd +t+l f +d  l++s+s D++++vWD+r  ++
   Q: 508  GHTDNITSLTFsPDsSLIASASMDNSVRVWDIRNTHC 544
           8***********999****************987665 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +spd++lla+g+++++ik+w+++++kl                                ++ l gh ++v++++f  d++ l++
   Q: 271  LNTAEISPDSKLLAAGFDNSCIKLWSLRSKKLksephpvdvsrihlacdileeeddeddnagteMKILRGHCGPVYSTRFLADSSGLLS 359
           5667889********************************************************************************** PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdls+++ ++ ++gh + v++l++sp++ +++sGshdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++Gs+D
   Q: 360  CSEDMSIRYWDLSSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGSTD 447
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s+ fsp++ +++s+s+D+s+r
   Q: 448  KTVRLWSAQQGNSVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSSLIASASMDNSVR 535
           ******************9.********************************************************************* PP
   S: 248  iWdlrsgdllktlqlhn...........ssvisva 271
           +Wd+r+  +     ++            s+v sv+
   Q: 536  VWDIRNTHCSAPADGSSgelvgvytgqmSNVLSVQ 570
           **999888887777766333333333334444444 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MKRVRTEQIQ MAVSCYLKRR QYVDSDGPLK QGLRLSQTAE EMAANLTVQS ESGCANIVSA 60
APCQAEPQQY EVQFGRLRNF LTDSDSQHSH EVMPLLYPLF VYLHLNLVQN SPKSTVESFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NGGCCTCCGA GTCCCAGGCG GCCGCGGGCG GCGTGGCCTG CAGTCGCCAG CTACACCTGG 60
AGGGCTCCGC GTTCCTGCTC GGGGTGGGTC CTGCCGGGGC GGCTGCCGGG CGCCCGCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	98.64	0.00e+00	1112.00
IUUC-Apl-003636	Anas platyrhynchos	92.39	0.00e+00	1107.00
IUUC-Aca-004229	Anolis carolinensis	91.51	0.00e+00	1076.00
IUUC-Ame-010599	Astyanax mexicanus	67.22	0.00e+00	818.00
IUUC-Bta-013404	Bos taurus	93.04	0.00e+00	1051.00
IUUC-Cja-019643	Callithrix jacchus	98.13	0.00e+00	1110.00
IUUC-Cfa-020913	Canis familiaris	98.81	0.00e+00	1115.00
IUUC-Cpo-021777	Cavia porcellus	94.57	0.00e+00	1073.00
IUUC-Csa-024184	Chlorocebus sabaeus	98.13	0.00e+00	1110.00
IUUC-Cho-024638	Choloepus hoffmanni	97.79	0.00e+00	1097.00
IUUC-Cin-025618	Ciona intestinalis	35.29	7.00e-90	324.00
IUUC-Csv-025874	Ciona savignyi	35.16	2.00e-90	327.00
IUUC-Dre-028817	Danio rerio	67.44	0.00e+00	809.00
IUUC-Dno-029969	Dasypus novemcinctus	88.62	0.00e+00	1036.00
IUUC-Dor-031117	Dipodomys ordii	95.42	0.00e+00	1108.00
IUUC-Ete-032712	Echinops telfairi	89.64	0.00e+00	987.00
IUUC-Eca-033742	Equus caballus	98.81	0.00e+00	1115.00
IUUC-Eeu-035096	Erinaceus europaeus	95.25	0.00e+00	1114.00
IUUC-Fca-035769	Felis catus	97.63	0.00e+00	1130.00
IUUC-Fal-036645	Ficedula albicollis	92.09	0.00e+00	1046.00
IUUC-Fso-038302	Fusarium solani	33.88	2.00e-40	160.00
IUUC-Gmo-038636	Gadus morhua	64.00	0.00e+00	776.00
IUUC-Gga-040144	Gallus gallus	92.36	0.00e+00	1080.00
IUUC-Gac-041716	Gasterosteus aculeatus	68.73	0.00e+00	818.00
IUUC-Ggo-044568	Gorilla gorilla	98.30	0.00e+00	1111.00
IUUC-Hsa-046178	Homo sapiens	98.30	0.00e+00	1111.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	89.13	0.00e+00	1070.00
IUUC-Lch-050501	Latimeria chalumnae	78.19	0.00e+00	863.00
IUUC-Loc-052895	Lepisosteus oculatus	82.83	0.00e+00	641.00
IUUC-Laf-053950	Loxodonta africana	93.38	0.00e+00	1071.00
IUUC-Mcc-055450	Macaca mulatta	98.13	0.00e+00	1107.00
IUUC-Meu-056182	Macropus eugenii	88.79	0.00e+00	1013.00
IUUC-Mga-059619	Meleagris gallopavo	92.36	0.00e+00	1080.00
IUUC-Mmr-061074	Microcebus murinus	96.45	0.00e+00	1118.00
IUUC-Mdo-062307	Monodelphis domestica	93.75	0.00e+00	891.00
IUUC-Mmu-063226	Mus musculus	92.70	0.00e+00	1047.00
IUUC-Mlu-067257	Myotis lucifugus	88.31	0.00e+00	1081.00
IUUC-Nle-070139	Nomascus leucogenys	98.13	0.00e+00	1109.00
IUUC-Opr-070243	Ochotona princeps	92.19	0.00e+00	1073.00
IUUC-Ont-072686	Oreochromis niloticus	68.33	0.00e+00	827.00
IUUC-Oan-073670	Ornithorhynchus anatinus	83.30	0.00e+00	832.00
IUUC-Ocu-074525	Oryctolagus cuniculus	97.28	0.00e+00	1124.00
IUUC-Ola-086524	Oryzias latipes	67.55	0.00e+00	845.00
IUUC-Oga-088540	Otolemur garnettii	96.94	0.00e+00	1095.00
IUUC-Oar-089793	Ovis aries	90.15	0.00e+00	988.00
IUUC-Ptr-091154	Pan troglodytes	98.30	0.00e+00	1111.00
IUUC-Pan-092759	Papio anubis	98.13	0.00e+00	1107.00
IUUC-Psi-094008	Pelodiscus sinensis	89.64	0.00e+00	1073.00
IUUC-Pma-094593	Petromyzon marinus	46.18	1.00e-133	469.00
IUUC-Pfo-097409	Poecilia formosa	67.39	0.00e+00	812.00
IUUC-Pab-097946	Pongo abelii	86.08	0.00e+00	951.00
IUUC-Pca-100727	Procavia capensis	89.81	0.00e+00	996.00
IUUC-Pva-103211	Pteropus vampyrus	84.89	0.00e+00	1017.00
IUUC-Ptt-103995	Puccinia triticina	42.48	1.00e-70	262.00
IUUC-Rno-105236	Rattus norvegicus	93.38	0.00e+00	1049.00
IUUC-Sha-106833	Sarcophilus harrisii	93.58	0.00e+00	1085.00
IUUC-Sar-113381	Sorex araneus	98.30	0.00e+00	1141.00
IUUC-Ssc-116421	Sus scrofa	95.59	0.00e+00	1141.00
IUUC-Tgu-117143	Taeniopygia guttata	92.87	0.00e+00	1112.00
IUUC-Tru-118680	Takifugu rubripes	67.17	0.00e+00	828.00
IUUC-Tsy-119622	Tarsius syrichta	82.00	0.00e+00	848.00
IUUC-Tni-120131	Tetraodon nigroviridis	67.33	0.00e+00	833.00
IUUC-Tbe-127656	Tupaia belangeri	91.48	7.00e-82	298.00
IUUC-Ttr-129171	Tursiops truncatus	94.57	0.00e+00	1073.00
IUUC-Xtr-132241	Xenopus tropicalis	80.68	0.00e+00	946.00
IUUC-Xma-133554	Xiphophorus maculatus	67.66	0.00e+00	745.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence