iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054239

UUCD1 version

UUC-LoA-00907

Ensembl Protein ID

ENSLAFP00000027018.1

UniProt Accession

G3UGR0; G3UGR0_LOXAF

Protein Name

Uncharacterized protein

Gene Name

RNF149

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000030178.1	ENSLAFT00000034779.1	ENSLAFP00000027018.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.20e-08	33.9	235	276

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e f  kd +++lpC+H+fh++C+  w         + +CP C+
   Q: 235  CAVCIENFkaKDVVRILPCKHIFHRTCIDPW------LLDHRTCPMCK 276
           ********88888******************......9999******6 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

AMAWRRPEAR VRSGGALALL ALALEWYSAL VSTAYVDPQT NLTVRSVSES GRFGDSSPRE 60
GAQGLLGLPA HPKGLGPGIP ASTCIFKDKV LVAARRNASA VVVYNEERYG NLTAAMSHAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCATGGCCT GGCGGCGGCC GGAAGCCCGC GTGCGGAGCG GCGGCGCGCT GGCGCTGCTG 60
GCCTTGGCGC TGTGCGCGCC GGCGGCCCGG GGCCGGGCGC TCGAGTGGTA CTCGGCCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035690--P:cellular response to drug
GO:0043409--P:negative regulation of MAPK cascade
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001968	Ailuropoda melanoleuca	74.64	1.00e-143	502.00
IUUC-Apl-004109	Anas platyrhynchos	72.33	2.00e-99	354.00
IUUC-Bta-012340	Bos taurus	72.21	2.00e-145	508.00
IUUC-Bol-016381	Brassica oleracea	36.36	5.00e-16	77.40
IUUC-Cja-019566	Callithrix jacchus	70.37	8.00e-138	483.00
IUUC-Cfa-020289	Canis familiaris	79.56	6.00e-103	366.00
IUUC-Cpo-021916	Cavia porcellus	57.69	1.00e-69	255.00
IUUC-Csa-024084	Chlorocebus sabaeus	69.43	5.00e-140	490.00
IUUC-Cho-024305	Choloepus hoffmanni	78.52	1.00e-116	412.00
IUUC-Cgl-026578	Colletotrichum gloeosporioides	48.08	1.00e-12	67.40
IUUC-Cme-027122	Cyanidioschyzon merolae	40.74	3.00e-13	70.50
IUUC-Dno-030098	Dasypus novemcinctus	73.93	1.00e-152	532.00
IUUC-Dor-030620	Dipodomys ordii	65.53	2.00e-117	415.00
IUUC-Ete-032306	Echinops telfairi	76.92	5.00e-159	553.00
IUUC-Fca-035950	Felis catus	80.60	2.00e-113	401.00
IUUC-Fal-037429	Ficedula albicollis	63.41	2.00e-124	438.00
IUUC-Fso-038141	Fusarium solani	42.67	5.00e-15	75.90
IUUC-Gga-041201	Gallus gallus	62.06	4.00e-120	424.00
IUUC-Ggo-045429	Gorilla gorilla	71.10	5.00e-136	476.00
IUUC-Hsa-046191	Homo sapiens	69.17	1.00e-139	489.00
IUUC-Itr-048018	Ictidomys tridecemlineatus	73.45	4.00e-130	457.00
IUUC-Kpa-049389	Komagataella pastoris	33.33	2.00e-11	62.80
IUUC-Lch-049498	Latimeria chalumnae	56.66	8.00e-117	413.00
IUUC-Lpe-051589	Leersia perrieri	43.24	8.00e-16	78.60
IUUC-Meu-056382	Macropus eugenii	66.95	5.00e-132	463.00
IUUC-Mor-056917	Magnaporthe oryzae	43.66	5.00e-13	68.90
IUUC-Mga-059435	Meleagris gallopavo	72.00	1.00e-65	242.00
IUUC-Mmr-061513	Microcebus murinus	73.07	3.00e-143	501.00
IUUC-Mdo-063028	Monodelphis domestica	68.08	1.00e-137	482.00
IUUC-Mmu-063545	Mus musculus	69.63	2.00e-126	445.00
IUUC-Mpu-066370	Mustela putorius furo	72.93	7.00e-136	476.00
IUUC-Mlu-067271	Myotis lucifugus	66.67	8.00e-122	429.00
IUUC-Nle-069207	Nomascus leucogenys	69.43	5.00e-140	490.00
IUUC-Opr-070704	Ochotona princeps	67.81	2.00e-90	325.00
IUUC-Oan-072837	Ornithorhynchus anatinus	63.38	3.00e-125	441.00
IUUC-Ocu-074671	Oryctolagus cuniculus	75.09	2.00e-112	398.00
IUUC-Oba-075032	Oryza barthii	43.24	2.00e-15	77.00
IUUC-Obr-076472	Oryza brachyantha	43.24	2.00e-15	77.00
IUUC-Ogl-077419	Oryza glaberrima	43.24	2.00e-15	77.00
IUUC-Ogu-078245	Oryza glumaepatula	43.24	2.00e-15	77.40
IUUC-Oin-079553	Oryza indica	43.24	1.00e-15	77.40
IUUC-Olo-080256	Oryza longistaminata	43.24	1.00e-15	77.40
IUUC-Ome-081196	Oryza meridionalis	43.24	2.00e-15	77.40
IUUC-Oni-083094	Oryza nivara	43.24	2.00e-15	77.40
IUUC-Opu-083198	Oryza punctata	43.24	2.00e-15	77.00
IUUC-Oru-085142	Oryza rufipogon	43.24	2.00e-15	77.00
IUUC-Osa-085890	Oryza sativa	43.24	2.00e-15	77.00
IUUC-Oga-089083	Otolemur garnettii	72.21	6.00e-145	506.00
IUUC-Oar-089254	Ovis aries	76.39	5.00e-106	376.00
IUUC-Ptr-090940	Pan troglodytes	72.36	4.00e-140	491.00
IUUC-Pan-092636	Papio anubis	72.08	3.00e-140	491.00
IUUC-Psi-093435	Pelodiscus sinensis	73.33	1.00e-93	335.00
IUUC-Pab-098525	Pongo abelii	71.51	7.00e-139	486.00
IUUC-Pop-099457	Populus trichocarpa	36.25	5.00e-15	76.30
IUUC-Pva-102395	Pteropus vampyrus	70.94	3.00e-143	501.00
IUUC-Pgr-103263	Puccinia graminis	37.36	6.00e-11	62.80
IUUC-Rno-105789	Rattus norvegicus	69.34	2.00e-126	445.00
IUUC-Sha-107305	Sarcophilus harrisii	73.33	1.00e-95	342.00
IUUC-Sbi-114569	Sorghum bicolor	37.72	3.00e-16	78.20
IUUC-Ssc-115598	Sus scrofa	71.92	2.00e-136	478.00
IUUC-Tgu-116463	Taeniopygia guttata	62.14	1.00e-116	412.00
IUUC-Tsy-118915	Tarsius syrichta	75.00	8.00e-99	352.00
IUUC-Tre-121978	Trichoderma reesei	51.02	2.00e-13	70.10
IUUC-Tme-126970	Tuber melanosporum	49.06	2.00e-13	70.50
IUUC-Tbe-127906	Tupaia belangeri	76.54	1.00e-73	269.00
IUUC-Vvi-131215	Vitis vinifera	36.25	1.00e-14	74.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence