iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106859

Ensembl Protein ID

ENSSHAP00000014955.1

UniProt Accession

G3WHQ0; G3WHQ0_SARHA

Genbank Protein ID

ENSSHAP00000014955

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01172436

Gene Name

MAP3K5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000012760.1	ENSSHAT00000015080.1	ENSSHAP00000014955.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	90.83	0.00e+00	2289.00	IUUC-Hsa-046906

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MSAEDSEGIT FPVPPFSPPG FCTFPEGGCS RRGGAAAAAA PGEGSPFPPP PPPAGSFWNV 60
EGSGASVTCT GGISAAAVAS GAPSAPRSRG NSTGAGGGSR RTTVAYVINE ASQGQLVVAE 120

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Nucleotide Sequence
(Fasta)

NGGCGGTGGA CCCCACCGCG ACCGCCGCAG AGCCCCTGGA AGAGATGAGC GCCGAGGATA 60
GCGAGGGCAT CACTTTCCCC GTTCCCCCGT TTAGCCCCCC GGGCTTTTGC ACCTTCCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR025136--DUF4071
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR013761--SAM/pointed
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF13281--DUF4071
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:1902911--C:protein kinase complex
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0070301--P:cellular response to hydrogen peroxide
GO:1902170--P:cellular response to reactive nitrogen species
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0007254--P:JNK cascade
GO:0038066--P:p38MAPK cascade
GO:0043280--P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0045663--P:positive regulation of myoblast differentiation
GO:1901216--P:positive regulation of neuron death
GO:0097300--P:programmed necrotic cell death

KEGG

shr:100917439

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002318	Ailuropoda melanoleuca	92.07	0.00e+00	2261.00
IUUC-Apl-003713	Anas platyrhynchos	89.65	0.00e+00	2074.00
IUUC-Aca-005331	Anolis carolinensis	87.60	0.00e+00	2073.00
IUUC-Ame-011158	Astyanax mexicanus	75.87	0.00e+00	1852.00
IUUC-Bta-012770	Bos taurus	90.82	0.00e+00	2371.00
IUUC-Cja-019656	Callithrix jacchus	91.55	0.00e+00	2397.00
IUUC-Cfa-020488	Canis familiaris	90.03	0.00e+00	2360.00
IUUC-Cpo-022516	Cavia porcellus	93.29	0.00e+00	2263.00
IUUC-Csa-023104	Chlorocebus sabaeus	94.99	0.00e+00	2246.00
IUUC-Cho-024379	Choloepus hoffmanni	88.12	0.00e+00	1203.00
IUUC-Dre-028836	Danio rerio	74.92	0.00e+00	1867.00
IUUC-Dno-029842	Dasypus novemcinctus	91.61	0.00e+00	2154.00
IUUC-Dor-030990	Dipodomys ordii	93.15	0.00e+00	1886.00
IUUC-Ete-032693	Echinops telfairi	81.50	0.00e+00	1909.00
IUUC-Eca-033337	Equus caballus	93.32	0.00e+00	2263.00
IUUC-Eeu-034602	Erinaceus europaeus	76.81	0.00e+00	1951.00
IUUC-Fca-035954	Felis catus	93.52	0.00e+00	1879.00
IUUC-Fal-037358	Ficedula albicollis	89.04	0.00e+00	2102.00
IUUC-Gmo-038836	Gadus morhua	77.49	0.00e+00	1748.00
IUUC-Gga-040443	Gallus gallus	89.38	0.00e+00	2230.00
IUUC-Gac-041634	Gasterosteus aculeatus	75.09	0.00e+00	1938.00
IUUC-Ggo-045263	Gorilla gorilla	89.15	0.00e+00	2317.00
IUUC-Hsa-046906	Homo sapiens	91.14	0.00e+00	2397.00
IUUC-Itr-048449	Ictidomys tridecemlineatus	93.39	0.00e+00	1080.00
IUUC-Lch-050213	Latimeria chalumnae	78.94	0.00e+00	1799.00
IUUC-Loc-051829	Lepisosteus oculatus	72.66	0.00e+00	1884.00
IUUC-Laf-053538	Loxodonta africana	90.63	0.00e+00	2393.00
IUUC-Mcc-054776	Macaca mulatta	91.07	0.00e+00	2411.00
IUUC-Mga-059636	Meleagris gallopavo	89.32	0.00e+00	2135.00
IUUC-Mmr-061323	Microcebus murinus	91.55	0.00e+00	2372.00
IUUC-Mdo-062146	Monodelphis domestica	96.69	0.00e+00	2469.00
IUUC-Mmu-064022	Mus musculus	90.84	0.00e+00	2355.00
IUUC-Mpu-066531	Mustela putorius furo	87.59	0.00e+00	2351.00
IUUC-Mlu-068181	Myotis lucifugus	86.99	0.00e+00	2300.00
IUUC-Nle-069758	Nomascus leucogenys	94.75	0.00e+00	2241.00
IUUC-Opr-070531	Ochotona princeps	85.48	0.00e+00	1425.00
IUUC-Ont-072014	Oreochromis niloticus	77.86	0.00e+00	1904.00
IUUC-Oan-073169	Ornithorhynchus anatinus	93.40	0.00e+00	2234.00
IUUC-Ocu-074050	Oryctolagus cuniculus	90.02	0.00e+00	2109.00
IUUC-Ola-086941	Oryzias latipes	80.34	0.00e+00	1541.00
IUUC-Oga-088796	Otolemur garnettii	90.47	0.00e+00	2357.00
IUUC-Oar-090445	Ovis aries	94.69	0.00e+00	2244.00
IUUC-Ptr-090846	Pan troglodytes	90.99	0.00e+00	2409.00
IUUC-Pan-091986	Papio anubis	91.14	0.00e+00	2414.00
IUUC-Psi-093805	Pelodiscus sinensis	89.90	0.00e+00	2242.00
IUUC-Pfo-097301	Poecilia formosa	73.54	0.00e+00	1927.00
IUUC-Pab-097662	Pongo abelii	92.05	0.00e+00	2354.00
IUUC-Pca-100755	Procavia capensis	91.55	0.00e+00	706.00
IUUC-Pva-102280	Pteropus vampyrus	83.24	0.00e+00	2167.00
IUUC-Rno-105547	Rattus norvegicus	89.40	0.00e+00	2332.00
IUUC-Sar-113714	Sorex araneus	81.89	0.00e+00	1890.00
IUUC-Tgu-117116	Taeniopygia guttata	87.90	0.00e+00	2181.00
IUUC-Tru-118088	Takifugu rubripes	76.73	0.00e+00	1941.00
IUUC-Tsy-119616	Tarsius syrichta	85.46	0.00e+00	1917.00
IUUC-Tni-120284	Tetraodon nigroviridis	74.57	0.00e+00	1894.00
IUUC-Tbe-127900	Tupaia belangeri	93.13	0.00e+00	837.00
IUUC-Ttr-128294	Tursiops truncatus	81.95	0.00e+00	2033.00
IUUC-Vpa-130470	Vicugna pacos	85.28	0.00e+00	2006.00
IUUC-Xtr-132396	Xenopus tropicalis	75.63	0.00e+00	1966.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence