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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Dme-031732
UUCD1 version UUC-DrM-00638
Ensembl Protein ID FBpp0290057
UniProt Accession Q8I077; Q9U4F9; Q9VAM3; Q8I077_DROME
Genbank Protein ID AAD55436.1; AAF56881.2; AAN14167.1; AAN71251.1; AGB96441.1
Protein Name BcDNA.LD22910; LD32685p; Ubiquitin specific protease 1, isoform C; Ubiquitin specific protease 1, isoform D; Ubiquitin specific protease 1, isoform E
Genbank Nucleotide ID AF181650; AE014297; AE014297; BT001496; AE014297
Gene Name CG15817; Usp1; BcDNA.LD22910; BcDNA:LD22910; Dmel_CG15817
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0028476 FBtr0300833 FBpp0290057
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Post-translational Modifications (PTMs)
dbPAFPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.90e-51 174.6 317 1037
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 3    lkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp........................................................ 42
           l N+gN+CY+NSv+ +L + p + ++l++   ++ln  ++                                                        
   Q: 317  LCNIGNSCYLNSVVYTLRFAPHFLHNLHH-LIQDLNVVQQtivrqqtarsaslgknvsaaqleharswsskdlatstdqysgqnggvnsgnggsgs 411
           66***************************.4444444444455566678888999999***********************************999 PP
   S: 43   .kepkgellkslqklfeelw....kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk........................ 109
            k+++++++++l++l ++l      ++++ +   +ll+a+++++  f+g++qqDa+Efl+++l+ ++e+ ++                        
   Q: 412  sKSTHQSVTEKLHELYNNLHgnemADSTEPYHADTLLHAIQDVNATFEGNQQQDAHEFLMCVLNCIRETNQSlikaigecpeviangyianpdevd 507
           999999*************887779999999999**********************************9977888888888887777654433322 PP
   S: 110  .....eknkpkeeeeeedkselsde....................................................................... 129
                                                                                                           
   Q: 508  tgegqD------------------Rtdstasqnlnagngslatsqttttktsffsrkskrkdevkpskstrvqsplkensptaggitgagtahata 585
           222220..................133344466778888888888888888888888888889********************************* PP
   S: 130  .............................................................aeekkkkknkslisdlFqgqlksqikclecdnvss 164
                                                                         ee+  + n ++ s  F+g +  ++kcl+c++++ 
   Q: 586  nslfylntvdlsgasstsgsastsasgvvstsaalptppqatkyssddemnsatvlkdkmrLEERIRELNLNFFSSDFEGIVVLTTKCLSCETITR 681
           *****************************************************999998887788888888************************* PP
   S: 165  reepfldlslpvp....gkeetkkeslqd....cL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekink 251
           +++ +ld+s+pvp    +     + +lqd     + +s  ++e ++genky+c++c++++ea ++++ + lP+ L+++L+Rf      +  ek+++
   Q: 682  QKQGMLDISVPVPisgyD-----NADLQDkpstYIqNSCITKEYFRGENKYSCNQCTGYTEAIRSISYEVLPRLLVIQLNRF-----SGGMEKVST 767
           *************55432.....3344431111444888999****************************************.....345679999 PP
   S: 252  kvefpleLdlspfcts..peekqkekkkYeLiavvvHsG.slssGHYvayvkn........................................... 301
           +v +   ++l  fc++  +  + ++ + Y+L++v+ H G +l  GHY+ay                                              
   Q: 768  YVPTT--FTLPCFCATccELGEGNKLHVYKLYSVITHVGaTLTVGHYIAYTCFldlasdyvncpkdrrntmtnsqtmasqavpsnenaapnngsss 861
           98665..6666555553322334459************************99889***************************************** PP
   S: 302  ................................................................................................ 301
                                                                                                           
   Q: 862  vastpviaaasalassgnilmkkmkfgrskasssgdmsknvkqvngiisknitngigklsisttcqgvnccamrlcctqqtsssnstscsdfsees 957
           ************************************************************************************************ PP
   S: 302  ..................................ekgk....WllfdDskVtevkeeevleetg......staYvlfYkr 337
                                              +g+    W+ +dD+k++++++ e++e  +       t+Y+lfY r
   Q: 958  lqngsnsnlsfggsgstyptgygstgrggvranyAHGGpdpiWYMCDDDKIKAMTQREFEELLSptrkitITPYLLFYAR 1037
           *******99999999999999999988888877633336788**************99999777999**99*******86 PP
   
Organism Drosophila melanogaster
Protein Sequence
(Fasta)
MHEYDVNERK EEPASLPPTQ NETTEINSQL RQDQQNQEQE NPLRQQDNSH PPQENPINQQ 60
EKDTLQVSVL YPLVVCAQLA DSQLVLTADT PKLSPVKKRQ RRVYVADTLR CYSLRSRQEP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-031732|DUB,USP|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CATCGATTAT TTCTCTTGCA TCCCTAGTCG TCCGCTCCAA TATAATAATT TCACTAGGCA 60
ACCTTAATGT AATAAGCGAC GTAAAACCGG GACTAAATAG CTCCAGAGCG AATGCTTATT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-031732|DUB,USP|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0005634--C:nucleus
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG dme:Dmel_CG15817
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001939 Ailuropoda melanoleuca 28.77 3.00e-18 86.30
IUUC-Apl-004204 Anas platyrhynchos 29.38 8.00e-19 88.20
IUUC-Aca-004637 Anolis carolinensis 31.11 2.00e-19 90.10
IUUC-Ame-011718 Astyanax mexicanus 30.48 9.00e-20 91.70
IUUC-Bta-012552 Bos taurus 29.19 8.00e-19 88.20
IUUC-Cja-019588 Callithrix jacchus 28.77 2.00e-18 87.40
IUUC-Cfa-020211 Canis familiaris 28.77 2.00e-18 87.00
IUUC-Cpo-021551 Cavia porcellus 28.30 2.00e-18 87.40
IUUC-Csa-024186 Chlorocebus sabaeus 28.77 2.00e-18 87.00
IUUC-Dre-028184 Danio rerio 29.11 4.00e-17 82.40
IUUC-Dno-029669 Dasypus novemcinctus 27.23 1.00e-18 88.20
IUUC-Dor-030168 Dipodomys ordii 28.49 3.00e-14 73.20
IUUC-Ete-032825 Echinops telfairi 28.12 6.00e-20 92.00
IUUC-Eca-033595 Equus caballus 29.25 3.00e-19 89.40
IUUC-Fal-037592 Ficedula albicollis 28.91 1.00e-16 81.30
IUUC-Gmo-039680 Gadus morhua 32.80 3.00e-22 99.40
IUUC-Gga-041196 Gallus gallus 29.38 1.00e-18 87.40
IUUC-Gac-042292 Gasterosteus aculeatus 32.78 3.00e-22 99.40
IUUC-Ggo-044671 Gorilla gorilla 28.77 1.00e-18 87.40
IUUC-Hsa-047020 Homo sapiens 28.77 1.00e-18 87.40
IUUC-Itr-048800 Ictidomys tridecemlineatus 29.25 9.00e-19 88.20
IUUC-Lch-050543 Latimeria chalumnae 31.79 4.00e-20 92.40
IUUC-Loc-052338 Lepisosteus oculatus 30.00 9.00e-18 84.70
IUUC-Laf-053707 Loxodonta africana 27.88 6.00e-19 89.00
IUUC-Mcc-055885 Macaca mulatta 28.77 2.00e-18 87.40
IUUC-Mga-059346 Meleagris gallopavo 29.38 2.00e-18 87.00
IUUC-Mmr-061612 Microcebus murinus 29.25 8.00e-19 88.20
IUUC-Mdo-062887 Monodelphis domestica 30.39 2.00e-17 84.00
IUUC-Mmu-064044 Mus musculus 30.39 3.00e-18 86.30
IUUC-Mpu-066847 Mustela putorius furo 28.77 3.00e-18 86.30
IUUC-Mlu-067684 Myotis lucifugus 29.25 1.00e-18 87.80
IUUC-Nle-070057 Nomascus leucogenys 28.77 1.00e-18 87.40
IUUC-Opr-070463 Ochotona princeps 28.77 7.00e-18 85.10
IUUC-Ont-071975 Oreochromis niloticus 33.16 1.00e-22 101.00
IUUC-Ocu-074840 Oryctolagus cuniculus 28.30 5.00e-18 85.50
IUUC-Ola-087088 Oryzias latipes 30.20 2.00e-21 97.10
IUUC-Oga-088472 Otolemur garnettii 28.77 1.00e-18 87.80
IUUC-Oar-089498 Ovis aries 29.19 5.00e-19 89.00
IUUC-Ptr-091395 Pan troglodytes 28.77 1.00e-18 87.40
IUUC-Pan-092462 Papio anubis 28.77 2.00e-18 87.40
IUUC-Pfo-096314 Poecilia formosa 29.52 6.00e-22 98.60
IUUC-Pab-098568 Pongo abelii 28.77 1.00e-18 87.40
IUUC-Pva-102853 Pteropus vampyrus 28.77 9.00e-19 88.20
IUUC-Rno-105573 Rattus norvegicus 28.77 1.00e-18 87.40
IUUC-Sha-107495 Sarcophilus harrisii 29.25 6.00e-20 91.70
IUUC-Sar-113545 Sorex araneus 28.77 4.00e-18 86.30
IUUC-Ssc-115962 Sus scrofa 28.77 8.00e-19 88.20
IUUC-Tgu-116731 Taeniopygia guttata 28.91 9.00e-17 81.30
IUUC-Tru-117893 Takifugu rubripes 30.77 6.00e-17 82.00
IUUC-Tni-119819 Tetraodon nigroviridis 32.84 3.00e-23 103.00
IUUC-Ttr-128404 Tursiops truncatus 28.77 1.00e-18 87.40
IUUC-Vpa-130205 Vicugna pacos 28.77 5.00e-19 89.00
IUUC-Xtr-132613 Xenopus tropicalis 31.78 6.00e-22 98.60
Created Date 25-Jun-2017

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