iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010642

Ensembl Protein ID

ENSAMXP00000019832.1

UniProt Accession

W5LJ20; W5LJ20_ASTMX

Genbank Protein ID

ENSAMXP00000019832

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

APWO01107821

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000019260.1	ENSAMXT00000019832.1	ENSAMXP00000019832.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-12	47.6	41	97

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++ v++++d++++nd +L +kkG+++++i   +++++W+ +++  +g +G +P  +v+++
   Q: 41   EDIVIAQHDFKPNNDSDLPFKKGEKLKII---QENGDWWLAKSLVTGDEGYIPCTYVARA 97
           5689*************************...999**********************997 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MGCTCSGQKK HKEKGHLNNN SAANNKSHPR QLGQRSADYD EDIVIAQHDF KPNNDSDLPF 60
KKGEKLKIIQ ENGDWWLAKS LVTGDEGYIP CTYVARAHTL EVERWFFKDL SRRETERLLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAATCATGA CCCGTAGTCG TGGTCAATGT ATGATCTAAA AGTAGATCTG TGTAGGATTA 60
GGGTTAAGGT TAGGGAAGTT TAGCCACACC AAGAGAACTA AATACGCTGT ATAACTCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002133	Ailuropoda melanoleuca	70.22	0.00e+00	685.00
IUUC-Apl-003307	Anas platyrhynchos	71.85	0.00e+00	696.00
IUUC-Aca-004357	Anolis carolinensis	70.65	0.00e+00	670.00
IUUC-Bta-012400	Bos taurus	70.09	0.00e+00	682.00
IUUC-Cfa-021056	Canis familiaris	69.78	0.00e+00	680.00
IUUC-Cpo-021779	Cavia porcellus	70.89	0.00e+00	696.00
IUUC-Csa-023557	Chlorocebus sabaeus	71.43	0.00e+00	689.00
IUUC-Dre-027517	Danio rerio	81.52	0.00e+00	833.00
IUUC-Eca-034218	Equus caballus	70.09	0.00e+00	678.00
IUUC-Fca-036015	Felis catus	69.11	0.00e+00	674.00
IUUC-Fal-036946	Ficedula albicollis	70.50	0.00e+00	687.00
IUUC-Gmo-038861	Gadus morhua	79.10	0.00e+00	751.00
IUUC-Gga-040822	Gallus gallus	71.93	0.00e+00	707.00
IUUC-Gac-041860	Gasterosteus aculeatus	73.16	0.00e+00	758.00
IUUC-Hsa-046719	Homo sapiens	70.44	0.00e+00	682.00
IUUC-Itr-048323	Ictidomys tridecemlineatus	71.01	0.00e+00	681.00
IUUC-Lch-050114	Latimeria chalumnae	70.69	0.00e+00	695.00
IUUC-Loc-052326	Lepisosteus oculatus	75.05	0.00e+00	786.00
IUUC-Laf-053387	Loxodonta africana	70.00	0.00e+00	681.00
IUUC-Mcc-055026	Macaca mulatta	71.43	0.00e+00	690.00
IUUC-Mga-059427	Meleagris gallopavo	71.65	0.00e+00	694.00
IUUC-Mmr-061660	Microcebus murinus	71.69	0.00e+00	692.00
IUUC-Mdo-062318	Monodelphis domestica	70.16	0.00e+00	684.00
IUUC-Mmu-063325	Mus musculus	70.22	0.00e+00	683.00
IUUC-Mpu-066582	Mustela putorius furo	70.00	0.00e+00	682.00
IUUC-Nle-069624	Nomascus leucogenys	71.24	0.00e+00	686.00
IUUC-Ont-072266	Oreochromis niloticus	78.12	0.00e+00	809.00
IUUC-Ocu-073907	Oryctolagus cuniculus	71.91	0.00e+00	690.00
IUUC-Ola-086668	Oryzias latipes	80.27	0.00e+00	768.00
IUUC-Oga-088057	Otolemur garnettii	71.01	0.00e+00	682.00
IUUC-Ptr-091551	Pan troglodytes	70.07	0.00e+00	653.00
IUUC-Pan-092173	Papio anubis	71.24	0.00e+00	687.00
IUUC-Psi-093895	Pelodiscus sinensis	71.62	0.00e+00	705.00
IUUC-Pfo-096608	Poecilia formosa	77.71	0.00e+00	809.00
IUUC-Pab-097598	Pongo abelii	71.40	0.00e+00	686.00
IUUC-Pva-102135	Pteropus vampyrus	70.67	0.00e+00	686.00
IUUC-Rno-104891	Rattus norvegicus	70.44	0.00e+00	688.00
IUUC-Sha-107192	Sarcophilus harrisii	70.82	0.00e+00	686.00
IUUC-Ssc-115696	Sus scrofa	70.44	0.00e+00	686.00
IUUC-Tgu-117056	Taeniopygia guttata	70.43	0.00e+00	687.00
IUUC-Tru-117621	Takifugu rubripes	75.61	0.00e+00	780.00
IUUC-Ttr-128457	Tursiops truncatus	69.98	0.00e+00	681.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence