iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045189

UUCD1 version

UUC-GoG-00336

Ensembl Protein ID

ENSGGOP00000008032.2

UniProt Accession

G3QYU0; G3QYU0_GORGO

Protein Name

Uncharacterized protein

Gene Name

EP300

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000008201.2	ENSGGOT00000008253.2	ENSGGOP00000008032.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	98.34	0.00e+00	2114.00	IUUC-Hsa-046884

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAENVVEPGP PSAKRPKLSS PALSASASDG TDFGSLFDLE HDLPDELINS TELGLTNGGD 60
INQLQTSLGM VQDAASKHKQ LSELLRSGSS PNLNMGVGGP GQVMASQAQQ SSPGLGLINS 120

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Nucleotide Sequence
(Fasta)

GCGGCGGCGG CGCGGAGCGC GGCGGCAGGA GGAGGGTTCG GAGGGTGGGG GCGCAGGCCC 60
GGGAGGGGGC ACCGGGAGGA GGTGAGTGTC TCTTGTCGCC TCCTCCTCTC CCCCCTTTTC 120

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Sequence Source

Ensembl

Keyword

KW-0012--Acyltransferase
KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR031162--CBP_P300_HAT
IPR013178--Histone_AcTrfase_Rtt109/CBP
IPR003101--KIX_dom
IPR009110--Nuc_rcpt_coact
IPR014744--Nuc_rcpt_coact_CREBbp
IPR010303--RING_CBP-p300
IPR000197--Znf_TAZ
IPR000433--Znf_ZZ

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51727--CBP_P300_HAT
PS50952--KIX
PS50134--ZF_TAZ
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00439--Bromodomain
PF09030--Creb_binding
PF06001--DUF902
PF08214--HAT_KAT11
PF02172--KIX
PF02135--zf-TAZ
PF00569--ZZ

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM01250--KAT11
SM00551--ZnF_TAZ
SM00291--ZnF_ZZ

Gene Ontology

GO:0005829--C:cytosol
GO:0000123--C:histone acetyltransferase complex
GO:0005667--C:transcription factor complex
GO:0031490--F:chromatin DNA binding
GO:0003684--F:damaged DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0004468--F:lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0097157--F:pre-mRNA intronic binding
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0001228--F:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0009887--P:animal organ morphogenesis
GO:0030183--P:B cell differentiation
GO:0034644--P:cellular response to UV
GO:0007623--P:circadian rhythm
GO:0045444--P:fat cell differentiation
GO:0007507--P:heart development
GO:0043969--P:histone H2B acetylation
GO:0043967--P:histone H4 acetylation
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0030324--P:lung development
GO:0010742--P:macrophage derived foam cell differentiation
GO:0035855--P:megakaryocyte development
GO:0018076--P:N-terminal peptidyl-lysine acetylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030220--P:platelet formation
GO:0043923--P:positive regulation by host of viral transcription
GO:0032092--P:positive regulation of protein binding
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0006990--P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0050821--P:protein stabilization
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0090043--P:regulation of tubulin deacetylation
GO:0043627--P:response to estrogen
GO:0001666--P:response to hypoxia
GO:0007519--P:skeletal muscle tissue development
GO:0001756--P:somitogenesis

KEGG

ggo:101153383

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002027	Ailuropoda melanoleuca	96.13	0.00e+00	1934.00
IUUC-Aca-005040	Anolis carolinensis	81.08	0.00e+00	1837.00
IUUC-Ame-011395	Astyanax mexicanus	86.00	0.00e+00	1469.00
IUUC-Bta-012649	Bos taurus	93.00	0.00e+00	2010.00
IUUC-Cel-018691	Caenorhabditis elegans	50.43	0.00e+00	846.00
IUUC-Cja-019649	Callithrix jacchus	96.02	0.00e+00	2164.00
IUUC-Cfa-020764	Canis familiaris	96.58	0.00e+00	1802.00
IUUC-Cpo-022345	Cavia porcellus	90.97	0.00e+00	3330.00
IUUC-Cre-022852	Chlamydomonas reinhardtii	34.84	4.00e-65	243.00
IUUC-Csa-023866	Chlorocebus sabaeus	99.52	0.00e+00	2118.00
IUUC-Cho-024951	Choloepus hoffmanni	97.86	0.00e+00	1241.00
IUUC-Csv-026122	Ciona savignyi	65.08	0.00e+00	677.00
IUUC-Dre-028500	Danio rerio	78.51	0.00e+00	1466.00
IUUC-Dor-030287	Dipodomys ordii	93.58	0.00e+00	1197.00
IUUC-Ete-032979	Echinops telfairi	90.11	0.00e+00	1774.00
IUUC-Eca-034048	Equus caballus	96.54	0.00e+00	1909.00
IUUC-Fca-035891	Felis catus	95.40	0.00e+00	2047.00
IUUC-Fal-037585	Ficedula albicollis	85.46	0.00e+00	1912.00
IUUC-Gmo-039348	Gadus morhua	84.97	0.00e+00	1447.00
IUUC-Gga-040916	Gallus gallus	84.81	0.00e+00	1920.00
IUUC-Gac-041642	Gasterosteus aculeatus	87.84	0.00e+00	1420.00
IUUC-Hsa-046884	Homo sapiens	99.45	0.00e+00	2116.00
IUUC-Hvu-047619	Hordeum vulgare	37.40	5.00e-68	253.00
IUUC-Itr-048564	Ictidomys tridecemlineatus	96.77	0.00e+00	1881.00
IUUC-Laf-054423	Loxodonta africana	94.52	0.00e+00	2192.00
IUUC-Mcc-054847	Macaca mulatta	99.17	0.00e+00	2120.00
IUUC-Meu-056217	Macropus eugenii	83.40	0.00e+00	1925.00
IUUC-Mga-059250	Meleagris gallopavo	81.15	0.00e+00	1942.00
IUUC-Mmr-061496	Microcebus murinus	96.35	0.00e+00	2096.00
IUUC-Mdo-062478	Monodelphis domestica	85.65	0.00e+00	1942.00
IUUC-Mmu-063456	Mus musculus	94.61	0.00e+00	1898.00
IUUC-Mac-064767	Musa acuminata	40.00	1.00e-75	278.00
IUUC-Mpu-065963	Mustela putorius furo	93.71	0.00e+00	1887.00
IUUC-Mlu-067185	Myotis lucifugus	95.32	0.00e+00	2024.00
IUUC-Ncr-068795	Neurospora crassa	37.97	1.00e-13	71.20
IUUC-Nle-069907	Nomascus leucogenys	99.67	0.00e+00	1910.00
IUUC-Opr-070324	Ochotona princeps	88.04	0.00e+00	1183.00
IUUC-Ont-072211	Oreochromis niloticus	79.43	0.00e+00	1458.00
IUUC-Oan-073723	Ornithorhynchus anatinus	88.80	0.00e+00	1860.00
IUUC-Ocu-074707	Oryctolagus cuniculus	95.66	0.00e+00	1897.00
IUUC-Oba-075590	Oryza barthii	33.52	2.00e-103	370.00
IUUC-Ogu-078580	Oryza glumaepatula	33.38	1.00e-103	372.00
IUUC-Ome-081615	Oryza meridionalis	33.52	2.00e-103	370.00
IUUC-Oni-082636	Oryza nivara	33.52	2.00e-103	371.00
IUUC-Opu-084073	Oryza punctata	32.97	5.00e-100	360.00
IUUC-Oru-084994	Oryza rufipogon	33.52	2.00e-103	371.00
IUUC-Osa-085860	Oryza sativa	42.26	7.00e-63	236.00
IUUC-Olu-087701	Ostreococcus lucimarinus	35.44	2.00e-62	234.00
IUUC-Oga-088700	Otolemur garnettii	94.99	0.00e+00	3456.00
IUUC-Oar-089787	Ovis aries	91.31	0.00e+00	2004.00
IUUC-Ptr-091620	Pan troglodytes	98.69	0.00e+00	2116.00
IUUC-Pan-092166	Papio anubis	97.79	0.00e+00	2138.00
IUUC-Psi-093992	Pelodiscus sinensis	82.76	0.00e+00	1972.00
IUUC-Ppa-095569	Physcomitrella patens	38.19	6.00e-71	263.00
IUUC-Pfo-097342	Poecilia formosa	85.01	0.00e+00	1384.00
IUUC-Pab-098235	Pongo abelii	98.20	0.00e+00	2109.00
IUUC-Pop-098947	Populus trichocarpa	40.00	4.00e-74	273.00
IUUC-Pca-100780	Procavia capensis	89.10	0.00e+00	1462.00
IUUC-Pva-103071	Pteropus vampyrus	94.92	0.00e+00	2180.00
IUUC-Sha-106736	Sarcophilus harrisii	92.05	0.00e+00	1674.00
IUUC-Smo-109420	Selaginella moellendorffii	38.27	1.00e-71	265.00
IUUC-Sar-113162	Sorex araneus	92.04	0.00e+00	852.00
IUUC-Ssc-116077	Sus scrofa	94.85	0.00e+00	2109.00
IUUC-Tgu-116872	Taeniopygia guttata	84.82	0.00e+00	1934.00
IUUC-Tru-118047	Takifugu rubripes	81.08	0.00e+00	1460.00
IUUC-Tsy-119451	Tarsius syrichta	95.00	0.00e+00	1318.00
IUUC-Tca-121835	Theobroma cacao	39.75	1.00e-73	272.00
IUUC-Tvi-122536	Trichoderma virens	43.04	2.00e-15	77.00
IUUC-Tae-124383	Triticum aestivum	38.73	8.00e-69	256.00
IUUC-Tur-126284	Triticum urartu	37.66	2.00e-68	255.00
IUUC-Tbe-127772	Tupaia belangeri	85.78	0.00e+00	1301.00
IUUC-Ttr-128325	Tursiops truncatus	98.03	0.00e+00	1459.00
IUUC-Vpa-130766	Vicugna pacos	93.14	0.00e+00	1309.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence