iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090928

Ensembl Protein ID

ENSPTRP00000021280.4

UniProt Accession

H2QIN7; H2QIN7_PANTR

Genbank Protein ID

JAA01072.1; JAA21540.1; JAA25262.1; JAA40304.1

Protein Name

Mitogen-activated protein kinase kinase kinase 2

Genbank Nucleotide ID

AACZ03020850; GABF01000605; GABD01007838; GABE01004435

Gene Name

MAP3K2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000012427.4	ENSPTRT00000023073.4	ENSPTRP00000021280.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	1.20e-15	57.4	43	122

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirsfaldlekpgkfedLlkavrtltelknsevalkYeDedGDlvtlksDedldkavslla...skksllrlliqk 83
           +vrvk++++ge r+  l++++p+k+edL+++ +     ++++++l+Y++++  +++l++++dldkav+ll+   ++ksl+ ll+ +
   Q: 43   DVRVKFEHRGEKRI--LQFPRPVKLEDLRSKAKI---AFGQSMDLHYTNNEL-VIPLTTQDDLDKAVELLDrsiHMKSLKILLVIN 122
           59**********77..******************...***************.***************************999975 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MDDQQALNSI MQDLAVLHKA SRPALSLQET RKAKSSSPKK QNDVRVKFEH RGEKRILQFP 60
RPVKLEDLRS KAKIAFGQSM DLHYTNNELV IPLTTQDDLD KAVELLDRSI HMKSLKILLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCATAAAGA ATGCTGATGG GAGAACCATT TTCCTAATTT TCAAATTGTT GAGCTATTTG 60
CCATAATGGG TGAGTTCAAA CTAAAAGCGT TTTTCAGTAA TAATTAAAGG ATAGAATGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS

PROSITE

PS51745--PB1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM

Pfam

PF00564--PB1
PF00069--Pkinase

SMART

SM00666--PB1
SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005524--F:ATP binding
GO:0004702--F:signal transducer, downstream of receptor, with serine/threonine kinase activity
GO:0030036--P:actin cytoskeleton organization
GO:0071260--P:cellular response to mechanical stimulus
GO:0045893--P:positive regulation of transcription, DNA-templated

KEGG

ptr:736244

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000356	Aegilops tauschii	50.19	4.00e-60	225.00
IUUC-Aml-002019	Ailuropoda melanoleuca	93.69	0.00e+00	1103.00
IUUC-Apl-003268	Anas platyrhynchos	89.33	0.00e+00	1085.00
IUUC-Aca-004909	Anolis carolinensis	83.80	0.00e+00	1011.00
IUUC-Ame-011723	Astyanax mexicanus	81.73	0.00e+00	964.00
IUUC-Bta-012860	Bos taurus	90.52	0.00e+00	1082.00
IUUC-Cja-019658	Callithrix jacchus	98.22	0.00e+00	1149.00
IUUC-Cfa-020514	Canis familiaris	98.71	0.00e+00	1160.00
IUUC-Cpo-022288	Cavia porcellus	88.19	0.00e+00	1037.00
IUUC-Csa-023826	Chlorocebus sabaeus	99.68	0.00e+00	1171.00
IUUC-Cho-024659	Choloepus hoffmanni	85.25	3.00e-152	531.00
IUUC-Csv-026215	Ciona savignyi	47.10	1.00e-129	456.00
IUUC-Dre-028720	Danio rerio	80.13	0.00e+00	974.00
IUUC-Dno-029457	Dasypus novemcinctus	97.42	0.00e+00	1126.00
IUUC-Dor-030165	Dipodomys ordii	83.03	5.00e-173	600.00
IUUC-Ete-032341	Echinops telfairi	97.09	0.00e+00	1140.00
IUUC-Eca-033357	Equus caballus	92.36	0.00e+00	1093.00
IUUC-Eeu-034768	Erinaceus europaeus	90.47	0.00e+00	1041.00
IUUC-Fca-036450	Felis catus	88.35	0.00e+00	1071.00
IUUC-Fal-037042	Ficedula albicollis	90.54	0.00e+00	1098.00
IUUC-Gmo-038470	Gadus morhua	67.95	0.00e+00	670.00
IUUC-Gac-041545	Gasterosteus aculeatus	79.49	0.00e+00	964.00
IUUC-Ggo-044919	Gorilla gorilla	99.84	0.00e+00	1173.00
IUUC-Hsa-046423	Homo sapiens	99.84	0.00e+00	1173.00
IUUC-Itr-048779	Ictidomys tridecemlineatus	97.90	0.00e+00	1147.00
IUUC-Lch-049757	Latimeria chalumnae	88.26	0.00e+00	1074.00
IUUC-Loc-052095	Lepisosteus oculatus	86.96	0.00e+00	1019.00
IUUC-Laf-054146	Loxodonta africana	97.90	0.00e+00	1150.00
IUUC-Mcc-055457	Macaca mulatta	99.68	0.00e+00	1171.00
IUUC-Meu-056073	Macropus eugenii	82.17	0.00e+00	835.00
IUUC-Mga-059921	Meleagris gallopavo	88.19	0.00e+00	1067.00
IUUC-Mmr-061086	Microcebus murinus	98.06	0.00e+00	1145.00
IUUC-Mdo-063081	Monodelphis domestica	93.55	0.00e+00	1128.00
IUUC-Mmu-063195	Mus musculus	96.12	0.00e+00	1134.00
IUUC-Mpu-066387	Mustela putorius furo	86.81	0.00e+00	1045.00
IUUC-Mlu-067395	Myotis lucifugus	94.17	0.00e+00	1123.00
IUUC-Nle-069756	Nomascus leucogenys	99.84	0.00e+00	1173.00
IUUC-Opr-070291	Ochotona princeps	91.11	0.00e+00	1107.00
IUUC-Ont-071421	Oreochromis niloticus	79.08	0.00e+00	940.00
IUUC-Ocu-074330	Oryctolagus cuniculus	97.90	0.00e+00	1158.00
IUUC-Ola-086643	Oryzias latipes	79.94	0.00e+00	963.00
IUUC-Oga-089147	Otolemur garnettii	94.37	0.00e+00	1077.00
IUUC-Oar-089464	Ovis aries	97.58	0.00e+00	1179.00
IUUC-Pan-092896	Papio anubis	99.63	0.00e+00	992.00
IUUC-Psi-093466	Pelodiscus sinensis	92.10	0.00e+00	969.00
IUUC-Pma-094492	Petromyzon marinus	68.54	0.00e+00	839.00
IUUC-Pab-097733	Pongo abelii	99.35	0.00e+00	1164.00
IUUC-Pca-100894	Procavia capensis	82.50	0.00e+00	942.00
IUUC-Pva-102822	Pteropus vampyrus	98.06	0.00e+00	1145.00
IUUC-Rno-106050	Rattus norvegicus	95.96	0.00e+00	1132.00
IUUC-Sha-106471	Sarcophilus harrisii	93.71	0.00e+00	1106.00
IUUC-Sar-112961	Sorex araneus	88.21	0.00e+00	1005.00
IUUC-Ssc-115588	Sus scrofa	98.23	0.00e+00	1188.00
IUUC-Tgu-116831	Taeniopygia guttata	87.44	0.00e+00	1038.00
IUUC-Tru-118223	Takifugu rubripes	78.11	0.00e+00	870.00
IUUC-Tsy-118788	Tarsius syrichta	68.17	0.00e+00	692.00
IUUC-Tni-120141	Tetraodon nigroviridis	78.06	0.00e+00	882.00
IUUC-Tbe-127378	Tupaia belangeri	76.94	0.00e+00	778.00
IUUC-Ttr-128905	Tursiops truncatus	87.28	0.00e+00	850.00
IUUC-Vpa-130781	Vicugna pacos	98.38	0.00e+00	1147.00
IUUC-Xtr-132672	Xenopus tropicalis	82.64	0.00e+00	950.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence