iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067102

Ensembl Protein ID

ENSMLUP00000008148.2

UniProt Accession

G1PCK3; G1PCK3_MYOLU

Genbank Protein ID

ENSMLUP00000008148

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02005348

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000008931.2	ENSMLUT00000008941.2	ENSMLUP00000008148.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-29	100.7	565	597
UBD/Beta-Prp	1.70e-45	155.6	561	775

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           gHtd v++la+   +  +l+s+s Dgt+++W+++
   Q: 565  GHTDAVWGLAYsaaH-QRLLSCSADGTLRLWNTT 597
           8**********9853.89**************76 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk......ghedsvlslsfspsgdklvsGshdrtirvwdletgqc 128
             l gh+++v+ + +s   + l+++s D+t+++w+     +  ++       g  +sv ++s++p  + +v+  +  +  ++++et+q 
   Q: 561  GPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFndnqefGIPASVDLVSSDP--SLMVASFSKGYTSIFNMETQQR 647
           5689******************************7776555555552555555555555566666..6666666788************ PP
   S: 129  lee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqt 211
           + +      t ++ +  +n v +hp+  + ++++ Dr ++++d +tgkl++ +   h ++v+sl++d+ng +l+sgs+d +++lw+l++
   Q: 648  ILTlesnldTTANSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVA-HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLES 735
           ***99**998899999999999***99**************************98.********************************* PP
   S: 212  gecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           ++c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 736  KTCIQEFTAHRkkfeESIHDVAFHPSKCYIASAGADALAK 775
           ***********999999******************97655 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

EGQMAGASVQ LQQQPPGAGG AKGLGPLAEA ARDGAAAAGA ARAQYSLPGI LHFLQHEWAR 60
FEVERAQWEV ERAELQAQIA FLQGERKGQE NLKKDLVRRI KMLEYALKQE RAKYHKLKYG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGGGCAGA TGGCAGGAGC GAGTGTCCAG GTCGGAGAAA CACTCAGGTC GGAGACGGGC 60
AGAGAGGGCT CAGTGCAGGA GCCGGGCCGG AGCAGCTCGC TTTGCGCTTG TTTCCTAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	97.14	0.00e+00	1350.00
IUUC-Apl-003927	Anas platyrhynchos	88.23	0.00e+00	1124.00
IUUC-Aca-004933	Anolis carolinensis	80.50	0.00e+00	1147.00
IUUC-Ame-010997	Astyanax mexicanus	76.07	0.00e+00	1051.00
IUUC-Bta-013077	Bos taurus	96.87	0.00e+00	1344.00
IUUC-Bci-013742	Botrytis cinerea	41.75	5.00e-23	103.00
IUUC-Cel-018443	Caenorhabditis elegans	48.36	7.00e-100	358.00
IUUC-Cja-018973	Callithrix jacchus	97.55	0.00e+00	1357.00
IUUC-Cfa-020988	Canis familiaris	93.60	0.00e+00	1221.00
IUUC-Cpo-022496	Cavia porcellus	96.33	0.00e+00	1351.00
IUUC-Csa-023829	Chlorocebus sabaeus	97.55	0.00e+00	1355.00
IUUC-Dre-028560	Danio rerio	70.31	0.00e+00	951.00
IUUC-Dno-029742	Dasypus novemcinctus	90.88	0.00e+00	1283.00
IUUC-Dor-030721	Dipodomys ordii	85.73	0.00e+00	1213.00
IUUC-Dse-031486	Dothistroma septosporum	26.67	2.00e-34	140.00
IUUC-Eca-033760	Equus caballus	96.87	0.00e+00	1273.00
IUUC-Eeu-034953	Erinaceus europaeus	96.88	0.00e+00	753.00
IUUC-Fca-036530	Felis catus	96.73	0.00e+00	1280.00
IUUC-Fal-037353	Ficedula albicollis	81.82	0.00e+00	896.00
IUUC-Gga-040132	Gallus gallus	88.16	0.00e+00	1139.00
IUUC-Gac-041713	Gasterosteus aculeatus	75.07	0.00e+00	1039.00
IUUC-Ggo-045455	Gorilla gorilla	87.14	0.00e+00	1157.00
IUUC-Hsa-046415	Homo sapiens	97.41	0.00e+00	1353.00
IUUC-Lch-050475	Latimeria chalumnae	83.58	0.00e+00	1167.00
IUUC-Loc-051859	Lepisosteus oculatus	79.73	0.00e+00	1116.00
IUUC-Laf-053537	Loxodonta africana	96.46	0.00e+00	1360.00
IUUC-Mcc-055817	Macaca mulatta	97.55	0.00e+00	1355.00
IUUC-Meu-055946	Macropus eugenii	67.78	0.00e+00	870.00
IUUC-Mpo-057337	Magnaporthe poae	24.80	7.00e-29	122.00
IUUC-Mga-059694	Meleagris gallopavo	88.21	0.00e+00	1115.00
IUUC-Mmr-060768	Microcebus murinus	95.24	0.00e+00	1369.00
IUUC-Mdo-061901	Monodelphis domestica	85.82	0.00e+00	1274.00
IUUC-Mmu-064154	Mus musculus	95.51	0.00e+00	1333.00
IUUC-Mpu-065827	Mustela putorius furo	91.88	0.00e+00	1337.00
IUUC-Ncr-068831	Neurospora crassa	39.60	6.00e-22	99.80
IUUC-Nle-070008	Nomascus leucogenys	97.01	0.00e+00	1283.00
IUUC-Opr-071067	Ochotona princeps	61.15	3.00e-177	614.00
IUUC-Ont-072025	Oreochromis niloticus	74.77	0.00e+00	1030.00
IUUC-Oan-072950	Ornithorhynchus anatinus	90.72	0.00e+00	1153.00
IUUC-Ocu-074316	Oryctolagus cuniculus	96.02	0.00e+00	1264.00
IUUC-Ola-087279	Oryzias latipes	73.08	0.00e+00	1005.00
IUUC-Oga-088284	Otolemur garnettii	97.01	0.00e+00	1352.00
IUUC-Oar-090304	Ovis aries	97.28	0.00e+00	1350.00
IUUC-Ptr-091052	Pan troglodytes	97.55	0.00e+00	1354.00
IUUC-Pan-092270	Papio anubis	93.49	0.00e+00	1315.00
IUUC-Psi-093907	Pelodiscus sinensis	87.59	0.00e+00	1040.00
IUUC-Pfo-097042	Poecilia formosa	73.19	0.00e+00	1106.00
IUUC-Pab-098110	Pongo abelii	97.55	0.00e+00	1354.00
IUUC-Pca-100266	Procavia capensis	83.54	0.00e+00	951.00
IUUC-Pva-102824	Pteropus vampyrus	92.93	0.00e+00	1321.00
IUUC-Pgr-103483	Puccinia graminis	36.71	4.00e-56	213.00
IUUC-Rno-105638	Rattus norvegicus	95.65	0.00e+00	1338.00
IUUC-Sha-107004	Sarcophilus harrisii	87.69	0.00e+00	1112.00
IUUC-Sre-115115	Sporisorium reilianum	33.85	4.00e-64	239.00
IUUC-Ssc-115280	Sus scrofa	97.55	0.00e+00	1355.00
IUUC-Tgu-116759	Taeniopygia guttata	88.78	0.00e+00	1145.00
IUUC-Tru-117944	Takifugu rubripes	74.50	0.00e+00	1026.00
IUUC-Tsy-119405	Tarsius syrichta	85.61	0.00e+00	1070.00
IUUC-Tni-120571	Tetraodon nigroviridis	74.03	0.00e+00	1032.00
IUUC-Tme-126990	Tuber melanosporum	26.15	2.00e-35	144.00
IUUC-Uma-129659	Ustilago maydis	34.70	1.00e-64	241.00
IUUC-Vpa-130294	Vicugna pacos	96.30	0.00e+00	1262.00
IUUC-Xma-134233	Xiphophorus maculatus	68.81	0.00e+00	911.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence