iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089629

Ensembl Protein ID

ENSOARP00000021513.1

UniProt Accession

W5QFL5; W5QFL5_SHEEP

Genbank Protein ID

ENSOARP00000021513

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01080911

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000020036.1	ENSOART00000021815.1	ENSOARP00000021513.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.40e-30	101.7	1320	1354
UBD/Beta-Prp	2.40e-44	151.9	1424	1637

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt  v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1320 GHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQE 1354
           899*****99767*****************99976 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.. 131
           + e+++++++++p+g +++ +++ ++++ wdl+ ++ + +l+gh   v++l++++  +g d +++Gs+d +i+++d+ +g       
   Q: 1424 SGENQINQISLNPTG-TFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDRisNGqDLIITGSKDHYIKMFDVTEGALGTVsp 1509
           56789*********9.99*************************************99888*****************9998765467 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
              ++ +h + +  +++h+  + l+sGs D+ ++ Wdl++++ll++   +h+d v  l++ +  + l+sg + g +klw++ t   v
   Q: 1510 thnFEPPHYDGIEALTIHG--DNLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWVCALAVVPGHPVLLSGCRGGILKLWNIDTFVPV 1594
           788999*************..6799**********************999************************************* PP
   S: 216  rtlnghtdnvksvrfspnderlvsgssDgsiriW...dlrsgdll 257
            +++gh+++++ + +   ++++ ++++D+++riW   +l+ g++ 
   Q: 1595 GEMKGHESPINAICVN--STHIFTAADDRTVRIWktrNLQDGQIS 1637
           ***********99888..****************88888888775 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

SSCFLPYRIR PQLAKERIEG CHICTSVTPG EPQVFLGKDK AFTFDYVFDI DSQQEQIYTQ 60
CIEKLIEGCF EGYNATVFAY GQTGAGKTYT MGTGFDVNII EEEQGIISRA VKHLFKSIEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTCCTGTT TTTTGCCTTA CAGAATAAGA CCACAGCTTG CCAAAGAAAG GATTGAGGGA 60
TGCCATATTT GTACATCTGT AACACCTGGA GAACCTCAAG TCTTCCTAGG CAAAGATAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	94.60	0.00e+00	3015.00
IUUC-Apl-003353	Anas platyrhynchos	83.22	0.00e+00	2622.00
IUUC-Aca-004467	Anolis carolinensis	84.45	0.00e+00	2709.00
IUUC-Ame-011430	Astyanax mexicanus	65.70	0.00e+00	1296.00
IUUC-Bta-013485	Bos taurus	96.88	0.00e+00	3039.00
IUUC-Cel-018402	Caenorhabditis elegans	52.95	7.00e-146	512.00
IUUC-Cja-019385	Callithrix jacchus	89.47	0.00e+00	2894.00
IUUC-Cfa-020986	Canis familiaris	94.95	0.00e+00	2972.00
IUUC-Cpo-022297	Cavia porcellus	90.70	0.00e+00	2849.00
IUUC-Csa-023685	Chlorocebus sabaeus	92.75	0.00e+00	2944.00
IUUC-Cho-024531	Choloepus hoffmanni	94.48	0.00e+00	1096.00
IUUC-Cin-025160	Ciona intestinalis	47.66	4.00e-88	318.00
IUUC-Csv-026158	Ciona savignyi	39.71	0.00e+00	766.00
IUUC-Dre-028532	Danio rerio	65.00	0.00e+00	1293.00
IUUC-Dno-029972	Dasypus novemcinctus	89.38	0.00e+00	2745.00
IUUC-Ete-032872	Echinops telfairi	77.75	0.00e+00	1013.00
IUUC-Eca-033518	Equus caballus	94.35	0.00e+00	2985.00
IUUC-Fca-036197	Felis catus	94.30	0.00e+00	2966.00
IUUC-Fal-037534	Ficedula albicollis	84.40	0.00e+00	2638.00
IUUC-Gmo-039407	Gadus morhua	66.67	0.00e+00	1362.00
IUUC-Gga-040687	Gallus gallus	82.63	0.00e+00	2589.00
IUUC-Gac-041626	Gasterosteus aculeatus	67.39	0.00e+00	2168.00
IUUC-Ggo-044457	Gorilla gorilla	93.71	0.00e+00	2948.00
IUUC-Hsa-046372	Homo sapiens	93.82	0.00e+00	2954.00
IUUC-Lch-049786	Latimeria chalumnae	59.06	0.00e+00	1870.00
IUUC-Loc-052689	Lepisosteus oculatus	73.76	0.00e+00	2374.00
IUUC-Laf-054018	Loxodonta africana	88.02	0.00e+00	2741.00
IUUC-Mcc-055558	Macaca mulatta	93.76	0.00e+00	2959.00
IUUC-Meu-056080	Macropus eugenii	83.29	0.00e+00	1630.00
IUUC-Mga-059283	Meleagris gallopavo	82.85	0.00e+00	2550.00
IUUC-Mmr-060773	Microcebus murinus	92.60	0.00e+00	2874.00
IUUC-Mdo-062688	Monodelphis domestica	87.93	0.00e+00	2588.00
IUUC-Mmu-063997	Mus musculus	90.81	0.00e+00	2825.00
IUUC-Mpu-066354	Mustela putorius furo	95.71	0.00e+00	2981.00
IUUC-Mlu-067599	Myotis lucifugus	93.47	0.00e+00	2928.00
IUUC-Nle-069477	Nomascus leucogenys	94.00	0.00e+00	2961.00
IUUC-Opr-070188	Ochotona princeps	81.56	0.00e+00	1788.00
IUUC-Ont-071717	Oreochromis niloticus	58.73	0.00e+00	1041.00
IUUC-Oan-073055	Ornithorhynchus anatinus	87.09	0.00e+00	2620.00
IUUC-Ocu-074302	Oryctolagus cuniculus	89.54	0.00e+00	2895.00
IUUC-Ola-086604	Oryzias latipes	64.40	0.00e+00	1268.00
IUUC-Oga-088799	Otolemur garnettii	92.59	0.00e+00	2662.00
IUUC-Pan-092214	Papio anubis	94.86	0.00e+00	2962.00
IUUC-Psi-093757	Pelodiscus sinensis	82.01	0.00e+00	2516.00
IUUC-Pfo-097448	Poecilia formosa	62.34	0.00e+00	1910.00
IUUC-Pab-097984	Pongo abelii	93.88	0.00e+00	2929.00
IUUC-Pca-101061	Procavia capensis	78.46	0.00e+00	1756.00
IUUC-Pva-102306	Pteropus vampyrus	94.56	0.00e+00	2900.00
IUUC-Rno-105354	Rattus norvegicus	89.08	0.00e+00	2784.00
IUUC-Sha-106938	Sarcophilus harrisii	88.66	0.00e+00	1807.00
IUUC-Ssc-115810	Sus scrofa	94.07	0.00e+00	2934.00
IUUC-Tgu-117076	Taeniopygia guttata	82.10	0.00e+00	2499.00
IUUC-Tru-118091	Takifugu rubripes	64.76	0.00e+00	1267.00
IUUC-Tsy-119020	Tarsius syrichta	95.38	0.00e+00	2972.00
IUUC-Tni-120813	Tetraodon nigroviridis	66.83	0.00e+00	2100.00
IUUC-Tbe-127494	Tupaia belangeri	80.82	0.00e+00	1013.00
IUUC-Ttr-128393	Tursiops truncatus	91.12	0.00e+00	2778.00
IUUC-Vpa-130675	Vicugna pacos	81.84	0.00e+00	776.00
IUUC-Xtr-132829	Xenopus tropicalis	78.37	0.00e+00	2500.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence