iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ang-009859

Ensembl Protein ID

CAK44021

UniProt Accession

A2QAE0; A2QAE0_ASPNC

Genbank Protein ID

CAK44021.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AM269981

Gene Name

An01g11160

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
An01g11160	CAK44021	CAK44021

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.80e-63	214.5	4	251

Active Site

Position(s)	Description	Evidence
97	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
182	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 5    vkewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressr.ksqvtsndlevvdediiktiffakqvigNsCatyAl 104
           + +w ++esd g+ft l+e++gvk++ q+eel sLd ++++++  pv+g+++lFk++ + ++ + +s++ts    + d d   ++ffa+q+i+N+C+t+A+
   Q: 4    GGGWSTIESDEGVFTSLIENLGVKDV-QFEELISLDADTIRSL-SPVYGVIFLFKWIRETQQPTsTSSTTSPPSGTYDTDPSPNLFFANQTIQNACGTQAI 102
           579***********************.****************.*************987765515778888999************************** PP
   S: 105  lsvllnc......edkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkp 198
           lsv+ln+      ++   +++G++l  +k++t ++ p+ +++al+n++ ++ +hn++ar  ++  ++ +++++   + +++hf++y++++g+lyeldgl+p
   Q: 103  LSVILNNdpssssTNPFpINIGPELHSFKDFTAGFPPDLRGEALSNSELIRSAHNAFARASPFVDETVRNNQD--EEGDVYHFIAYTPVDGKLYELDGLQP 201
           *******9999754444789*******************************************9998886554..599*********************** PP
   S: 199  fPldlgkkketeelkdklkvvraflerikllesdeirfnllaivadrrviktl 251
            P+ +g ++ +e  ++ ++v+r   +ri  + ++e rfnl+a+v d rv  + 
   Q: 202  HPISHGGCTAEEFPEKVIEVLR---QRIARYPEGETRFNLMAVVRDLRVTAKE 251
           **********999999999999...*********************9996554 PP

Organism

Aspergillus niger

Protein Sequence
(Fasta)

MADGGGWSTI ESDEGVFTSL IENLGVKDVQ FEELISLDAD TIRSLSPVYG VIFLFKWIRE 60
TQQPTSTSST TSPPSGTYDT DPSPNLFFAN QTIQNACGTQ AILSVILNND PSSSSTNPFP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGACG GCGGAGGCTG GAGCACAATC GAGTCCGACG AGGTACGCAA TCTGCACATC 60
AAAGCATACA TATAGAGCCA CAAACCTAAC CAGCAAACCT TTAGGGCGTC TTCACCTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0034399--C:nuclear periphery
GO:0031595--C:nuclear proteasome complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	40.12	5.00e-61	226.00
IUUC-Aml-001866	Ailuropoda melanoleuca	35.94	1.00e-51	194.00
IUUC-Atr-002966	Amborella trichopoda	47.04	2.00e-54	204.00
IUUC-Apl-003306	Anas platyrhynchos	32.81	6.00e-44	169.00
IUUC-Aca-004763	Anolis carolinensis	36.62	6.00e-52	195.00
IUUC-Aly-005581	Arabidopsis lyrata	40.00	9.00e-56	208.00
IUUC-Ath-007283	Arabidopsis thaliana	39.72	3.00e-57	213.00
IUUC-Ago-007999	Ashbya gossypii	36.27	1.00e-42	164.00
IUUC-Acl-008231	Aspergillus clavatus	78.93	1.00e-133	467.00
IUUC-Afl-008557	Aspergillus flavus	74.92	1.00e-131	460.00
IUUC-Afu-008988	Aspergillus fumigatus	80.19	2.00e-136	476.00
IUUC-Ani-009420	Aspergillus nidulans	73.95	4.00e-125	438.00
IUUC-Aor-010145	Aspergillus oryzae	74.92	1.00e-131	460.00
IUUC-Ate-010347	Aspergillus terreus	72.19	2.00e-126	443.00
IUUC-Ame-010791	Astyanax mexicanus	35.59	2.00e-54	203.00
IUUC-Bgr-012298	Blumeria graminis	58.47	2.00e-96	343.00
IUUC-Bta-013251	Bos taurus	36.05	9.00e-52	195.00
IUUC-Bci-013786	Botrytis cinerea	63.46	5.00e-112	395.00
IUUC-Bdi-014132	Brachypodium distachyon	46.95	3.00e-59	220.00
IUUC-Bol-015611	Brassica oleracea	43.27	3.00e-58	216.00
IUUC-Bra-017769	Brassica rapa	44.27	3.00e-58	216.00
IUUC-Cel-018604	Caenorhabditis elegans	34.91	1.00e-48	184.00
IUUC-Cja-019768	Callithrix jacchus	32.95	2.00e-46	177.00
IUUC-Cfa-020207	Canis familiaris	35.94	1.00e-51	194.00
IUUC-Cpo-021925	Cavia porcellus	34.69	2.00e-47	180.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	47.90	3.00e-55	206.00
IUUC-Csa-023958	Chlorocebus sabaeus	36.28	6.00e-52	196.00
IUUC-Cho-024928	Choloepus hoffmanni	36.96	4.00e-09	53.90
IUUC-Cin-025771	Ciona intestinalis	35.09	1.00e-49	188.00
IUUC-Csv-026149	Ciona savignyi	35.24	6.00e-53	199.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	49.20	5.00e-85	305.00
IUUC-Cne-026955	Cryptococcus neoformans	36.14	5.00e-51	192.00
IUUC-Cme-027104	Cyanidioschyzon merolae	32.86	3.00e-40	157.00
IUUC-Dre-027409	Danio rerio	36.16	6.00e-53	199.00
IUUC-Dno-028921	Dasypus novemcinctus	35.94	4.00e-51	192.00
IUUC-Dor-030891	Dipodomys ordii	39.51	5.00e-25	107.00
IUUC-Dse-031170	Dothistroma septosporum	56.15	4.00e-93	332.00
IUUC-Dme-031677	Drosophila melanogaster	37.61	2.00e-53	200.00
IUUC-Ete-032646	Echinops telfairi	41.83	2.00e-33	135.00
IUUC-Eca-033805	Equus caballus	40.96	2.00e-42	165.00
IUUC-Eeu-035305	Erinaceus europaeus	33.50	2.00e-26	111.00
IUUC-Fca-035846	Felis catus	33.33	4.00e-47	180.00
IUUC-Fal-037597	Ficedula albicollis	36.24	3.00e-45	173.00
IUUC-Fox-037670	Fusarium oxysporum	58.82	4.00e-87	312.00
IUUC-Fso-038243	Fusarium solani	57.84	8.00e-86	308.00
IUUC-Gmo-038499	Gadus morhua	33.86	3.00e-44	170.00
IUUC-Ggr-039975	Gaeumannomyces graminis	55.06	1.00e-81	294.00
IUUC-Gga-040904	Gallus gallus	35.69	2.00e-52	197.00
IUUC-Gac-042058	Gasterosteus aculeatus	36.36	1.00e-51	194.00
IUUC-Gma-043030	Glycine max	48.15	8.00e-59	218.00
IUUC-Ggo-044699	Gorilla gorilla	40.00	2.00e-50	190.00
IUUC-Hsa-046227	Homo sapiens	35.94	4.00e-52	196.00
IUUC-Hvu-047359	Hordeum vulgare	40.71	7.00e-61	225.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	33.24	7.00e-47	179.00
IUUC-Lch-049829	Latimeria chalumnae	38.24	1.00e-53	201.00
IUUC-Lpe-050899	Leersia perrieri	48.19	3.00e-59	220.00
IUUC-Loc-052264	Lepisosteus oculatus	37.50	3.00e-51	193.00
IUUC-Lma-053110	Leptosphaeria maculans	61.26	2.00e-89	320.00
IUUC-Laf-053639	Loxodonta africana	35.94	1.00e-51	194.00
IUUC-Mcc-055506	Macaca mulatta	36.05	6.00e-52	196.00
IUUC-Meu-056267	Macropus eugenii	36.88	7.00e-38	150.00
IUUC-Mor-057001	Magnaporthe oryzae	53.94	3.00e-84	303.00
IUUC-Mpo-057608	Magnaporthe poae	56.15	2.00e-48	183.00
IUUC-Mtr-057731	Medicago truncatula	47.92	6.00e-63	232.00
IUUC-Mla-059016	Melampsora laricipopulina	43.81	6.00e-42	161.00
IUUC-Mga-060178	Meleagris gallopavo	34.85	1.00e-45	174.00
IUUC-Mvi-060353	Microbotryum violaceum	35.31	1.00e-48	184.00
IUUC-Mmr-060738	Microcebus murinus	36.25	9.00e-52	195.00
IUUC-Mdo-062625	Monodelphis domestica	39.54	1.00e-43	169.00
IUUC-Mmu-063619	Mus musculus	35.83	6.00e-52	195.00
IUUC-Mac-065301	Musa acuminata	42.18	2.00e-64	237.00
IUUC-Mpu-066058	Mustela putorius furo	35.94	1.00e-51	194.00
IUUC-Mlu-067292	Myotis lucifugus	35.94	6.00e-52	196.00
IUUC-Nfi-068275	Neosartorya fischeri	80.50	5.00e-147	511.00
IUUC-Ncr-068713	Neurospora crassa	59.55	9.00e-106	374.00
IUUC-Nle-069013	Nomascus leucogenys	36.28	2.00e-51	194.00
IUUC-Opr-070741	Ochotona princeps	40.56	5.00e-42	164.00
IUUC-Ont-072688	Oreochromis niloticus	35.42	4.00e-51	192.00
IUUC-Oan-073167	Ornithorhynchus anatinus	39.54	3.00e-43	167.00
IUUC-Ocu-074303	Oryctolagus cuniculus	36.16	9.00e-51	192.00
IUUC-Oba-075002	Oryza barthii	46.47	1.00e-59	221.00
IUUC-Obr-076392	Oryza brachyantha	47.23	2.00e-61	227.00
IUUC-Ogl-077271	Oryza glaberrima	46.47	1.00e-59	221.00
IUUC-Ogu-078493	Oryza glumaepatula	46.84	2.00e-60	224.00
IUUC-Oin-080084	Oryza indica	46.84	2.00e-60	224.00
IUUC-Olo-080803	Oryza longistaminata	46.84	2.00e-60	224.00
IUUC-Ome-081146	Oryza meridionalis	46.84	2.00e-60	224.00
IUUC-Oni-082146	Oryza nivara	46.84	2.00e-60	224.00
IUUC-Opu-083633	Oryza punctata	46.84	3.00e-60	223.00
IUUC-Oru-084789	Oryza rufipogon	46.84	2.00e-60	224.00
IUUC-Osa-086196	Oryza sativa	46.84	2.00e-60	224.00
IUUC-Ola-087126	Oryzias latipes	36.99	2.00e-53	200.00
IUUC-Olu-087665	Ostreococcus lucimarinus	37.93	1.00e-51	194.00
IUUC-Oga-089140	Otolemur garnettii	33.43	2.00e-47	181.00
IUUC-Oar-090296	Ovis aries	35.62	3.00e-50	190.00
IUUC-Ptr-090566	Pan troglodytes	35.94	4.00e-52	196.00
IUUC-Pan-092052	Papio anubis	36.28	6.00e-52	196.00
IUUC-Psi-093723	Pelodiscus sinensis	36.24	2.00e-45	173.00
IUUC-Pma-094568	Petromyzon marinus	42.13	4.00e-46	176.00
IUUC-Pno-095120	Phaeosphaeria nodorum	59.94	4.00e-95	339.00
IUUC-Ppa-095761	Physcomitrella patens	46.52	3.00e-58	217.00
IUUC-Pfo-096210	Poecilia formosa	37.30	9.00e-53	198.00
IUUC-Pab-098463	Pongo abelii	36.16	6.00e-52	196.00
IUUC-Pop-099109	Populus trichocarpa	39.94	7.00e-58	215.00
IUUC-Pca-100108	Procavia capensis	40.56	3.00e-47	180.00
IUUC-Ppe-101176	Prunus persica	38.50	6.00e-56	209.00
IUUC-Pva-102629	Pteropus vampyrus	41.20	4.00e-49	186.00
IUUC-Pgr-103419	Puccinia graminis	41.67	2.00e-44	171.00
IUUC-Pte-104207	Pyrenophora teres	57.46	4.00e-46	175.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	58.33	4.00e-94	335.00
IUUC-Rno-105579	Rattus norvegicus	32.62	1.00e-42	165.00
IUUC-Sha-107100	Sarcophilus harrisii	39.00	7.00e-41	160.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	46.39	6.00e-74	268.00
IUUC-Spo-108371	Schizosaccharomyces pombe	48.24	2.00e-77	280.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	61.62	2.00e-93	333.00
IUUC-Smo-109396	Selaginella moellendorffii	38.03	4.00e-54	203.00
IUUC-Sit-110630	Setaria italica	46.92	5.00e-61	226.00
IUUC-Sly-110972	Solanum lycopersicum	39.65	2.00e-56	211.00
IUUC-Stu-112185	Solanum tuberosum	41.00	3.00e-64	236.00
IUUC-Sar-113294	Sorex araneus	31.59	5.00e-41	159.00
IUUC-Sbi-113951	Sorghum bicolor	46.84	7.00e-62	229.00
IUUC-Ssc-115501	Sus scrofa	34.85	2.00e-46	177.00
IUUC-Tgu-117152	Taeniopygia guttata	36.24	3.00e-45	173.00
IUUC-Tru-118388	Takifugu rubripes	36.68	1.00e-51	195.00
IUUC-Tsy-119109	Tarsius syrichta	36.16	1.00e-51	194.00
IUUC-Tni-120048	Tetraodon nigroviridis	36.68	4.00e-52	196.00
IUUC-Tca-121750	Theobroma cacao	44.24	2.00e-63	233.00
IUUC-Tre-122130	Trichoderma reesei	57.99	6.00e-97	345.00
IUUC-Tvi-122284	Trichoderma virens	55.74	3.00e-90	323.00
IUUC-Tae-124082	Triticum aestivum	40.12	7.00e-61	225.00
IUUC-Tur-126366	Triticum urartu	38.43	1.00e-39	155.00
IUUC-Tme-127187	Tuber melanosporum	57.49	7.00e-104	368.00
IUUC-Tbe-127705	Tupaia belangeri	40.16	6.00e-38	149.00
IUUC-Ttr-128225	Tursiops truncatus	40.96	2.00e-42	165.00
IUUC-Vda-129912	Verticillium dahliae	54.66	1.00e-87	314.00
IUUC-Vpa-130552	Vicugna pacos	40.00	1.00e-41	161.00
IUUC-Vvi-130881	Vitis vinifera	39.34	4.00e-57	213.00
IUUC-Xtr-131934	Xenopus tropicalis	36.36	2.00e-52	197.00
IUUC-Xma-133312	Xiphophorus maculatus	37.30	1.00e-52	198.00
IUUC-Yli-134487	Yarrowia lipolytica	45.95	9.00e-71	258.00
IUUC-Zma-135639	Zea mays	40.20	1.00e-51	194.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence