iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000013413.1	ENSSHAT00000015867.1	ENSSHAP00000015739.1
ENSSHAG00000013413.1	ENSSHAT00000015868.1	ENSSHAP00000015740.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.60e-40	137.1	6	148

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.. 87
           Rlk+el+ l+++pp+gi++ ++ + ++++++++ilG ++tpYe+g+Fkle+++pe+YPf+PPk++flt+i+hPn++++G++Cl++lk  
   Q: 6    RLKRELHLLATEPPPGITCWQNAN-QMDDLRAQILGGTNTPYEKGIFKLEVSIPERYPFEPPKIRFLTPIYHPNIDSAGRICLDVLKlp 93
           99********************99.7************************************************************888 PP
   S: 88   ....eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
                + + s+ +   +vl+siq l++epnp++pl +++++++k n+ ++ k++r
   Q: 94   pkniCTGNFSTLSLALTVLTSIQLLMSEPNPDDPLMADISSEFKYNKPTFLKNAR 148
           888888999999999***********************************99987 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MQRASRLKRE LHLLATEPPP GITCWQNANQ MDDLRAQILG GTNTPYEKGI FKLEVSIPER 60
YPFEPPKIRF LTPIYHPNID SAGRICLDVL KLPPKNICTG NFSTLSLALT VLTSIQLLMS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNCAC CGCAGCTGCG CAGAGGACGG CTCAGGCACG CGGGCCAATA 60
GTCAGCCGCG GAGCTTCAGG GAGGCCCAAT CCGAGCGGCG CTCTTGGCTT TACAAACCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005730--C:nucleolus
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006281--P:DNA repair
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000366	Aegilops tauschii	49.69	2.00e-39	157.00
IUUC-Aml-001392	Ailuropoda melanoleuca	72.14	5.00e-82	296.00
IUUC-Atr-003069	Amborella trichopoda	46.58	2.00e-41	162.00
IUUC-Apl-003914	Anas platyrhynchos	77.71	3.00e-68	249.00
IUUC-Aca-004381	Anolis carolinensis	64.71	1.00e-72	265.00
IUUC-Aly-006059	Arabidopsis lyrata	49.38	2.00e-38	152.00
IUUC-Ath-007669	Arabidopsis thaliana	55.56	6.00e-36	144.00
IUUC-Ame-011372	Astyanax mexicanus	57.75	5.00e-59	219.00
IUUC-Bta-012479	Bos taurus	69.65	4.00e-76	276.00
IUUC-Bdi-014043	Brachypodium distachyon	51.57	2.00e-43	170.00
IUUC-Bol-016011	Brassica oleracea	42.56	1.00e-36	147.00
IUUC-Bra-017419	Brassica rapa	47.17	7.00e-36	144.00
IUUC-Cja-019773	Callithrix jacchus	75.25	8.00e-84	302.00
IUUC-Cfa-020043	Canis familiaris	74.13	8.00e-83	298.00
IUUC-Cpo-021481	Cavia porcellus	74.13	7.00e-83	299.00
IUUC-Csa-024083	Chlorocebus sabaeus	74.63	1.00e-84	305.00
IUUC-Cho-024386	Choloepus hoffmanni	74.33	1.00e-77	281.00
IUUC-Cin-025419	Ciona intestinalis	62.58	3.00e-56	210.00
IUUC-Csv-026224	Ciona savignyi	63.87	5.00e-57	213.00
IUUC-Cme-027179	Cyanidioschyzon merolae	45.81	1.00e-35	141.00
IUUC-Dre-028800	Danio rerio	70.32	7.00e-64	236.00
IUUC-Dno-029833	Dasypus novemcinctus	75.12	4.00e-83	300.00
IUUC-Ete-032625	Echinops telfairi	78.26	1.00e-64	237.00
IUUC-Eca-033821	Equus caballus	84.62	2.00e-74	270.00
IUUC-Eeu-034932	Erinaceus europaeus	89.47	2.00e-48	185.00
IUUC-Fca-036398	Felis catus	73.13	3.00e-82	297.00
IUUC-Fal-037564	Ficedula albicollis	69.19	6.00e-71	259.00
IUUC-Gmo-039142	Gadus morhua	73.55	1.00e-64	238.00
IUUC-Gga-041054	Gallus gallus	65.15	2.00e-68	251.00
IUUC-Gac-041370	Gasterosteus aculeatus	70.97	7.00e-64	235.00
IUUC-Ggo-045370	Gorilla gorilla	75.62	4.00e-85	306.00
IUUC-Hsa-046513	Homo sapiens	76.12	1.00e-85	308.00
IUUC-Hvu-047694	Hordeum vulgare	49.37	1.00e-40	160.00
IUUC-Itr-049076	Ictidomys tridecemlineatus	72.14	2.00e-81	295.00
IUUC-Lch-050484	Latimeria chalumnae	75.54	1.00e-59	222.00
IUUC-Loc-051967	Lepisosteus oculatus	63.30	1.00e-65	241.00
IUUC-Laf-053377	Loxodonta africana	74.63	8.00e-84	302.00
IUUC-Mcc-055453	Macaca mulatta	75.12	5.00e-85	306.00
IUUC-Meu-056745	Macropus eugenii	82.09	5.00e-92	329.00
IUUC-Mga-059729	Meleagris gallopavo	64.65	2.00e-67	248.00
IUUC-Mmr-060581	Microcebus murinus	74.13	1.00e-84	304.00
IUUC-Mdo-062434	Monodelphis domestica	83.08	2.00e-88	319.00
IUUC-Mmu-064379	Mus musculus	67.66	2.00e-74	271.00
IUUC-Mac-064647	Musa acuminata	50.00	1.00e-39	155.00
IUUC-Mpu-066713	Mustela putorius furo	72.64	2.00e-82	297.00
IUUC-Mlu-067525	Myotis lucifugus	82.69	4.00e-73	266.00
IUUC-Nle-069757	Nomascus leucogenys	76.62	4.00e-86	310.00
IUUC-Opr-070756	Ochotona princeps	69.65	2.00e-78	284.00
IUUC-Ont-071956	Oreochromis niloticus	62.69	2.00e-66	244.00
IUUC-Oan-072745	Ornithorhynchus anatinus	76.83	4.00e-71	259.00
IUUC-Ocu-074423	Oryctolagus cuniculus	74.13	8.00e-83	298.00
IUUC-Oba-075569	Oryza barthii	51.90	1.00e-41	164.00
IUUC-Obr-076131	Oryza brachyantha	52.53	1.00e-41	164.00
IUUC-Ogl-077132	Oryza glaberrima	51.90	1.00e-41	164.00
IUUC-Ogu-078880	Oryza glumaepatula	51.59	6.00e-42	165.00
IUUC-Oin-079748	Oryza indica	51.59	6.00e-42	165.00
IUUC-Olo-080501	Oryza longistaminata	51.59	3.00e-42	166.00
IUUC-Ome-081248	Oryza meridionalis	51.59	1.00e-41	164.00
IUUC-Oni-083033	Oryza nivara	51.59	6.00e-42	165.00
IUUC-Opu-083664	Oryza punctata	51.59	6.00e-42	165.00
IUUC-Oru-084580	Oryza rufipogon	51.59	6.00e-42	165.00
IUUC-Osa-085721	Oryza sativa	51.59	6.00e-42	165.00
IUUC-Ola-087559	Oryzias latipes	61.88	7.00e-65	239.00
IUUC-Oga-088420	Otolemur garnettii	74.26	1.00e-83	301.00
IUUC-Oar-090082	Ovis aries	69.12	4.00e-75	273.00
IUUC-Ptr-091134	Pan troglodytes	75.62	3.00e-85	306.00
IUUC-Pan-091735	Papio anubis	74.63	1.00e-84	305.00
IUUC-Psi-094064	Pelodiscus sinensis	66.50	2.00e-72	265.00
IUUC-Pma-094609	Petromyzon marinus	65.81	4.00e-59	219.00
IUUC-Ppa-095553	Physcomitrella patens	52.60	8.00e-41	160.00
IUUC-Pfo-096710	Poecilia formosa	72.26	2.00e-63	234.00
IUUC-Pab-098126	Pongo abelii	76.12	1.00e-85	308.00
IUUC-Pop-099108	Populus trichocarpa	49.37	8.00e-40	158.00
IUUC-Pca-100338	Procavia capensis	72.14	5.00e-79	286.00
IUUC-Ppe-101239	Prunus persica	51.41	9.00e-36	144.00
IUUC-Pva-102756	Pteropus vampyrus	69.33	6.00e-55	205.00
IUUC-Rno-105211	Rattus norvegicus	67.16	2.00e-72	264.00
IUUC-Smo-109052	Selaginella moellendorffii	49.35	4.00e-39	153.00
IUUC-Sit-110464	Setaria italica	53.59	1.00e-40	161.00
IUUC-Sly-110971	Solanum lycopersicum	53.85	6.00e-40	158.00
IUUC-Stu-112126	Solanum tuberosum	54.49	2.00e-40	160.00
IUUC-Sar-113633	Sorex araneus	70.14	6.00e-78	283.00
IUUC-Sbi-114875	Sorghum bicolor	50.63	6.00e-41	162.00
IUUC-Ssc-116375	Sus scrofa	71.14	7.00e-76	276.00
IUUC-Tgu-117292	Taeniopygia guttata	77.71	2.00e-66	243.00
IUUC-Tru-118157	Takifugu rubripes	60.65	1.00e-49	188.00
IUUC-Tsy-119260	Tarsius syrichta	74.63	1.00e-83	301.00
IUUC-Tni-120162	Tetraodon nigroviridis	59.60	4.00e-64	236.00
IUUC-Tca-121255	Theobroma cacao	49.70	4.00e-33	135.00
IUUC-Tae-123184	Triticum aestivum	50.00	2.00e-39	156.00
IUUC-Tbe-127296	Tupaia belangeri	73.63	2.00e-83	300.00
IUUC-Ttr-128443	Tursiops truncatus	68.42	9.00e-77	278.00
IUUC-Vpa-130689	Vicugna pacos	71.64	3.00e-79	287.00
IUUC-Vvi-130925	Vitis vinifera	49.11	3.00e-40	157.00
IUUC-Xma-133779	Xiphophorus maculatus	67.84	7.00e-64	236.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence