iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.40e-14	52.8	184	228

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
           lw ++s++ SLq+LC++a+++c++ + +   dkLPLP +L+++L+++++
   Q: 184  LW-RPSKVLSLQDLCCRAVVSCTPVHLV---DKLPLPVALRSHLKSFSM 228
           67.99********************888...***************976 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MMSSLGSPVR AYDFLLKFLL VGDSDVGKGE ILASLQDGAA ESPYGHPAGI DHKTTTILLD 60
GRRVKLQLWD TSGQGRFCTI FRSYSRGAQG VILVYDIANR WSFDGINRWI KEIDEHAPGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGGACCCT CCGCCGCCTG CGCGCAGCCT GGGGCCGGCA TGGGCGGGGT GGCTGGGCCG 60
GCATGATGAG CTCCTTGGGC AGCCCGGTGC GGGCCTACGA TTTTTTACTT AAGTTCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027417--P-loop_NTPase
IPR005225--Small_GTP-bd_dom
IPR001806--Small_GTPase
IPR001496--SOCS_box

PROSITE

PS50225--SOCS

Pfam

PF00071--Ras
PF07525--SOCS_box

SMART

SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005768--C:endosome
GO:0005886--C:plasma membrane
GO:0008021--C:synaptic vesicle
GO:0005525--F:GTP binding
GO:0072659--P:protein localization to plasma membrane
GO:0009306--P:protein secretion
GO:0016567--P:protein ubiquitination
GO:0007264--P:small GTPase mediated signal transduction
GO:0006904--P:vesicle docking involved in exocytosis

KEGG

rno:303754

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003206	Anas platyrhynchos	90.13	9.00e-129	452.00
IUUC-Aca-005004	Anolis carolinensis	88.48	5.00e-138	483.00
IUUC-Ame-011456	Astyanax mexicanus	85.25	3.00e-144	504.00
IUUC-Bta-012683	Bos taurus	88.85	4.00e-148	516.00
IUUC-Cja-018870	Callithrix jacchus	85.25	1.00e-140	491.00
IUUC-Cfa-020527	Canis familiaris	91.43	1.00e-115	409.00
IUUC-Cpo-021644	Cavia porcellus	94.40	1.00e-150	525.00
IUUC-Csa-023150	Chlorocebus sabaeus	94.60	1.00e-159	555.00
IUUC-Cho-024716	Choloepus hoffmanni	90.85	2.00e-87	314.00
IUUC-Dre-028614	Danio rerio	84.59	5.00e-142	496.00
IUUC-Eca-033492	Equus caballus	92.67	3.00e-131	460.00
IUUC-Fca-035705	Felis catus	91.34	9.00e-128	448.00
IUUC-Gga-040925	Gallus gallus	88.85	2.00e-150	524.00
IUUC-Ggo-045012	Gorilla gorilla	84.53	3.00e-140	490.00
IUUC-Hsa-046747	Homo sapiens	94.24	9.00e-159	552.00
IUUC-Loc-052325	Lepisosteus oculatus	87.10	4.00e-148	516.00
IUUC-Laf-053340	Loxodonta africana	91.01	2.00e-151	527.00
IUUC-Mcc-054711	Macaca mulatta	92.17	2.00e-155	541.00
IUUC-Mga-059204	Meleagris gallopavo	88.85	5.00e-150	523.00
IUUC-Mmu-064144	Mus musculus	98.57	5.00e-165	573.00
IUUC-Mpu-066352	Mustela putorius furo	90.52	3.00e-127	447.00
IUUC-Nle-070096	Nomascus leucogenys	93.53	3.00e-157	546.00
IUUC-Opr-070662	Ochotona princeps	90.29	3.00e-149	520.00
IUUC-Ont-072397	Oreochromis niloticus	83.16	4.00e-139	486.00
IUUC-Ocu-074559	Oryctolagus cuniculus	92.09	2.00e-145	508.00
IUUC-Olo-080270	Oryza longistaminata	35.23	5.00e-12	65.50
IUUC-Oga-088133	Otolemur garnettii	92.81	1.00e-156	545.00
IUUC-Oar-089702	Ovis aries	86.96	6.00e-120	422.00
IUUC-Ptr-090544	Pan troglodytes	94.64	2.00e-148	518.00
IUUC-Pan-092812	Papio anubis	94.60	1.00e-159	555.00
IUUC-Psi-093120	Pelodiscus sinensis	89.21	5.00e-152	530.00
IUUC-Pab-098735	Pongo abelii	94.60	1.00e-159	555.00
IUUC-Pva-102361	Pteropus vampyrus	91.20	6.00e-138	483.00
IUUC-Sar-113518	Sorex araneus	86.72	2.00e-129	454.00
IUUC-Ssc-115719	Sus scrofa	89.55	8.00e-143	499.00
IUUC-Tsy-119011	Tarsius syrichta	91.58	9.00e-105	372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence