iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-123611

Ensembl Protein ID

TRIAE_CS42_U_TGACv1_643786_AA2135080.1

UniProt Accession

A0A1D6DJG7; A0A1D6DJG7_WHEAT

Protein Name

Coatomer subunit alpha

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_U_TGACv1_643786_AA2135080	TRIAE_CS42_U_TGACv1_643786_AA2135080.1	TRIAE_CS42_U_TGACv1_643786_AA2135080.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-38	131.6	50	86
UBD/Beta-Prp	4.80e-77	261.7	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW+++t+++l
   Q: 50   HDGPVRGVHFhaTQPLFVSGGDDYKIKVWNYKTHRCL 86
           99*********6449********************98 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDr 74
           t +++++++++ + f+p +++++++  +g i+ wd+++g+ll ++ +h+++v+ v f+ +++++v+g++D+
   Q: 3    TKFETKSNRVKGLSFHPRRPWILASLHSGVIQMWDYRMGTLLDRFDEHDGPVRGVHFHATQPLFVSGGDDY 73
           67889999*************************************************************** PP
   S: 75   tikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvv 145
            ikvw+++t  c+ tl+gh d++++++f+ +  ++vs+s+d+tir+w++++++c+  +l+gh++ v+c+++
   Q: 74   KIKVWNYKTHRCLFTLTGHLDYIRTVQFHHEYPWIVSASDDQTIRIWNWQSRTCVA-VLTGHNHYVMCASF 143
           ********************************************************.************** PP
   S: 146  hpdgnllvsGslDrtvrlWdl...........................ktgkllrtltgghtdsvyslsfd 189
           hp+++l+vs+slD+tvr+Wd+                             + + + l+g h++ v++ sf+
   Q: 144  HPKEDLVVSASLDQTVRVWDIgalrkktvspaddilrltqmntdlfggVDAVVKYVLEG-HDRGVNWASFH 213
           ***********************************977777777776444444444466.*********** PP
   S: 190  sngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllk 258
           ++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+siriWd ++++ ++
   Q: 214  PTLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRIWDATKRTGIQ 284
           *********************777668******************************************** PP
   S: 259  tlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           t+ +++++++  a+ +++ n l++g  ds   ++kl++++p
   Q: 285  TFRREHDRFWILAA-HPEMNLLAAG-HDSGMIVFKLERERP 323
           **************.6666655555.689999999988765 PP

Organism

Triticum aestivum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHPR RPWILASLHS GVIQMWDYRM GTLLDRFDEH DGPVRGVHFH 60
ATQPLFVSGG DDYKIKVWNY KTHRCLFTLT GHLDYIRTVQ FHHEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTCTCCCC CAGAATCCAA CGGCGGCGCC GCCTCTCACC ACCTCAGCAC TCAGCAGCGT 60
CGGAAACCCA GATCTCCTCT TGCCCGAGAT CTAAAGCACC TTCCTCCTCC CCATCATCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	99.92	0.00e+00	2393.00
IUUC-Aca-005154	Anolis carolinensis	78.43	2.00e-95	342.00
IUUC-Ath-007058	Arabidopsis thaliana	77.30	0.00e+00	1936.00
IUUC-Ago-007992	Ashbya gossypii	43.58	0.00e+00	993.00
IUUC-Ang-009756	Aspergillus niger	47.56	0.00e+00	1140.00
IUUC-Cel-018115	Caenorhabditis elegans	54.93	0.00e+00	932.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	69.47	0.00e+00	1242.00
IUUC-Cin-025572	Ciona intestinalis	50.16	0.00e+00	1248.00
IUUC-Fox-037738	Fusarium oxysporum	47.69	0.00e+00	1128.00
IUUC-Fso-038153	Fusarium solani	47.12	0.00e+00	1124.00
IUUC-Nle-069634	Nomascus leucogenys	65.42	0.00e+00	947.00
IUUC-Ogl-077364	Oryza glaberrima	92.78	0.00e+00	2302.00
IUUC-Oin-079274	Oryza indica	92.61	0.00e+00	2298.00
IUUC-Olo-080466	Oryza longistaminata	96.45	0.00e+00	1659.00
IUUC-Oru-084274	Oryza rufipogon	92.69	0.00e+00	2300.00
IUUC-Osa-085565	Oryza sativa	92.69	0.00e+00	2300.00
IUUC-Psi-093044	Pelodiscus sinensis	54.25	0.00e+00	895.00
IUUC-Ppa-095390	Physcomitrella patens	68.49	0.00e+00	1721.00
IUUC-Pca-100413	Procavia capensis	60.25	0.00e+00	692.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	39.58	0.00e+00	736.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	44.23	0.00e+00	1065.00
IUUC-Spo-108217	Schizosaccharomyces pombe	43.91	0.00e+00	1048.00
IUUC-Sit-109697	Setaria italica	91.47	0.00e+00	2281.00
IUUC-Stu-112564	Solanum tuberosum	78.51	0.00e+00	2009.00
IUUC-Sre-115209	Sporisorium reilianum	55.66	0.00e+00	1004.00
IUUC-Tsy-119105	Tarsius syrichta	51.44	0.00e+00	1026.00
IUUC-Tme-127170	Tuber melanosporum	47.85	0.00e+00	1182.00
IUUC-Tbe-127882	Tupaia belangeri	68.71	2.00e-128	454.00
IUUC-Vda-129828	Verticillium dahliae	46.63	0.00e+00	1117.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence