iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066674

Ensembl Protein ID

ENSMPUP00000009937.1

UniProt Accession

M3YF30; M3YF30_MUSPF

Genbank Protein ID

ENSMPUP00000009937

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01095768

Gene Name

TRIM22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000010012.1	ENSMPUT00000010097.1	ENSMPUP00000009937.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.60e-08	32.6	15	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw.pglknssskefrCPlCr 46
           C+iCl+ +   pl+l+CgH f++ C+ +  +++   + +e +CP+C+
   Q: 15   CPICLDLLTM-PLSLDCGHSFCQACITAKgQDSGVHQGGESNCPVCQ 60
           ********88.***************7777677777999*******7 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MNFPAQMNIQ MEVTCPICLD LLTMPLSLDC GHSFCQACIT AKGQDSGVHQ GGESNCPVCQ 60
CKYQFWNLRP NQPLANIVKK VKENMSPWQK KLCEHHGEKL LIFCKEDGKL ICQHCAQSLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCTGACACC CTTGTGGTGT CTTCTCGCTG CTATTTTTTA AGTTTCCATT CTGCTTCCTT 60
TCTTTCATTT CCCCTTCTCA GATTTTAAGT TTCATTTCTA CCCAGTTCCT AAACAGAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0008270--F:zinc ion binding
GO:0010508--P:positive regulation of autophagy
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0070206--P:protein trimerization
GO:0032880--P:regulation of protein localization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002371	Ailuropoda melanoleuca	87.85	0.00e+00	925.00
IUUC-Cfa-021080	Canis familiaris	84.21	0.00e+00	882.00
IUUC-Csa-023785	Chlorocebus sabaeus	65.46	0.00e+00	655.00
IUUC-Cme-027197	Cyanidioschyzon merolae	41.07	1.00e-06	48.90
IUUC-Eca-034336	Equus caballus	66.00	2.00e-180	626.00
IUUC-Gma-042739	Glycine max	30.10	2.00e-08	53.50
IUUC-Ggo-044550	Gorilla gorilla	65.26	0.00e+00	629.00
IUUC-Hsa-046363	Homo sapiens	65.86	0.00e+00	661.00
IUUC-Laf-053647	Loxodonta africana	60.69	6.00e-166	577.00
IUUC-Mcc-054743	Macaca mulatta	65.46	0.00e+00	658.00
IUUC-Nle-068980	Nomascus leucogenys	66.47	0.00e+00	668.00
IUUC-Ptr-091300	Pan troglodytes	65.26	0.00e+00	652.00
IUUC-Pan-092605	Papio anubis	61.04	5.00e-170	590.00
IUUC-Pab-098535	Pongo abelii	65.26	0.00e+00	657.00
IUUC-Pca-100529	Procavia capensis	55.71	2.00e-153	535.00
IUUC-Tsy-119330	Tarsius syrichta	62.45	5.00e-173	600.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence