iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007861

Ensembl Protein ID

AAS54205

UniProt Accession

Q751J2; SHO1_ASHGO

Genbank Protein ID

AAS54205.1

Protein Name

High osmolarity signaling protein SHO1; Osmosensor SHO1

Genbank Nucleotide ID

AE016820

Gene Name

SHO1; AGL286C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AGL286C	AAS54205	AAS54205

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.20e-12	42.8	266	325

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqndd..eLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + ++ ++ly yea  +d  e ++++G++++v    + ++ W+k+ k+++g  G++P+n+ve ++
   Q: 266  FPYTAKALYAYEADASDayEISFQQGEILRVG---DIEGRWWKA-KKANGETGIIPSNYVELVD 325
           67899*******9999877999*********7...9********.69**************987 PP

Organism

Ashbya gossypii

Functional Description
(View)

Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.

Protein Sequence
(Fasta)

MTLRATKARQ QRVSPHIGHT FSFGNLVGDP FAISTLSIST IAWLITLGGG IATKKMPHFS 60
WWGIAFQFVM MVCFVVIYLW DLVDYYRGFL AAGVGVAFVY STNSCSQLIY QEEPQQAAGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACATTGA GAGCGACGAA AGCGAGACAG CAGCGGGTGT CGCCGCATAT CGGGCACACG 60
TTCAGCTTCG GGAACCTGGT GGGTGACCCG TTTGCGATTT CGACGTTGTC GATCAGCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0346--Stress response
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005935--C:cellular bud neck
GO:0044697--C:HICS complex
GO:0016021--C:integral component of membrane
GO:0043332--C:mating projection tip
GO:0005886--C:plasma membrane
GO:0005034--F:osmosensor activity
GO:0034605--P:cellular response to heat
GO:0030010--P:establishment of cell polarity
GO:0007231--P:osmosensory signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:0001402--P:signal transduction involved in filamentous growth

KEGG

ago:AGOS_AGL286C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018144	Caenorhabditis elegans	42.62	3.00e-09	53.90
IUUC-Cfa-021259	Canis familiaris	44.68	9.00e-08	49.70
IUUC-Dre-028357	Danio rerio	32.81	2.00e-07	48.50
IUUC-Eca-034408	Equus caballus	47.62	7.00e-07	47.00
IUUC-Mga-059574	Meleagris gallopavo	48.33	2.00e-08	49.70
IUUC-Oan-072976	Ornithorhynchus anatinus	32.63	2.00e-09	54.30
IUUC-Opu-083939	Oryza punctata	27.08	1.50e+00	24.60
IUUC-Oar-089278	Ovis aries	41.82	6.00e-08	50.10
IUUC-Pab-097908	Pongo abelii	49.09	1.00e-07	48.90
IUUC-Tsy-119180	Tarsius syrichta	42.37	4.00e-09	53.90
IUUC-Tni-119974	Tetraodon nigroviridis	37.70	2.00e-09	54.30

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence