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Tag Content
iUUCD ID IUUC-Dre-028308
Ensembl Protein ID ENSDARP00000065716.6
UniProt Accession F1QE02; F1QE02_DANRE
Genbank Protein ID ENSDARP00000065716
Protein Name Vav 2 guanine nucleotide exchange factor
Genbank Nucleotide ID CR812470
Gene Name vav2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000044718.7 ENSDART00000143987.1 ENSDARP00000122666.1
ENSDARG00000044718.7 ENSDART00000065717.6 ENSDARP00000065716.6
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 4.10e-17 62.8 824 875
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            + y++ a +  eL+l++Gd+v++ +k   d+gW+kg  e++g+ G fP+ +v 
   Q: 824  VARYNFAARDMRELSLREGDIVKIYSKIGGDQGWWKG--EANGRIGWFPSTYVD 875
           578**********************************..9************96 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MEEWRQCGRW LIDCKVLPPN HRVVWPSAVV FDLAQALRDG VLLCQMLHNL SPGSVDLKQI 60
NFRPQMSQFL CLKNIRTFLK VCHDKFGLRN SELFDPFDLF DVRDFGKVIS ALSRISHNSI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028308|UBD,SH3|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGCCCGTCC GCACTCACGC GAGCGGAGAA ATCAAAACAC TCAAACCATC CACACTGAGA 60
AACAACCGAG AAATCCTCGC TACTCAACGG ACGAATGATC AGCACGGAGC CATCGCGGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028308|UBD,SH3|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc
Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain
PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2
Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2
PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3
Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001437 Ailuropoda melanoleuca 79.64 0.00e+00 1304.00
IUUC-Apl-003262 Anas platyrhynchos 81.88 0.00e+00 1385.00
IUUC-Ath-007340 Arabidopsis thaliana 38.30 6.00e-03 35.40
IUUC-Ame-011608 Astyanax mexicanus 92.27 0.00e+00 1660.00
IUUC-Bta-013147 Bos taurus 77.93 0.00e+00 1109.00
IUUC-Cel-018578 Caenorhabditis elegans 31.89 3.00e-79 290.00
IUUC-Cja-018877 Callithrix jacchus 77.98 0.00e+00 1217.00
IUUC-Cfa-020315 Canis familiaris 76.16 0.00e+00 1048.00
IUUC-Cpo-021543 Cavia porcellus 77.76 0.00e+00 1122.00
IUUC-Csa-024204 Chlorocebus sabaeus 80.11 0.00e+00 1415.00
IUUC-Cin-025115 Ciona intestinalis 36.21 1.00e-151 530.00
IUUC-Csv-025995 Ciona savignyi 35.60 2.00e-152 533.00
IUUC-Dno-029584 Dasypus novemcinctus 73.12 0.00e+00 978.00
IUUC-Dor-031014 Dipodomys ordii 69.42 0.00e+00 1031.00
IUUC-Eca-033448 Equus caballus 79.28 0.00e+00 1382.00
IUUC-Eeu-035182 Erinaceus europaeus 71.89 5.00e-171 595.00
IUUC-Fca-035460 Felis catus 77.25 0.00e+00 1113.00
IUUC-Fal-036684 Ficedula albicollis 82.27 0.00e+00 1430.00
IUUC-Gmo-038816 Gadus morhua 83.62 0.00e+00 1219.00
IUUC-Gga-040999 Gallus gallus 79.71 0.00e+00 1368.00
IUUC-Gac-041353 Gasterosteus aculeatus 85.24 0.00e+00 1289.00
IUUC-Ggo-044558 Gorilla gorilla 81.86 0.00e+00 1430.00
IUUC-Hsa-046208 Homo sapiens 81.86 0.00e+00 1429.00
IUUC-Itr-047931 Ictidomys tridecemlineatus 76.69 0.00e+00 1030.00
IUUC-Loc-052827 Lepisosteus oculatus 91.36 0.00e+00 1654.00
IUUC-Laf-054009 Loxodonta africana 77.94 0.00e+00 1340.00
IUUC-Mcc-055054 Macaca mulatta 81.75 0.00e+00 1428.00
IUUC-Mga-060106 Meleagris gallopavo 82.33 0.00e+00 1398.00
IUUC-Mmr-061118 Microcebus murinus 80.05 0.00e+00 1378.00
IUUC-Mdo-062380 Monodelphis domestica 76.98 0.00e+00 1128.00
IUUC-Mmu-063135 Mus musculus 80.97 0.00e+00 1407.00
IUUC-Mpu-066135 Mustela putorius furo 76.18 0.00e+00 1226.00
IUUC-Nle-069465 Nomascus leucogenys 74.63 0.00e+00 1283.00
IUUC-Ont-071945 Oreochromis niloticus 91.27 0.00e+00 1605.00
IUUC-Oan-073384 Ornithorhynchus anatinus 78.80 0.00e+00 1088.00
IUUC-Ola-087499 Oryzias latipes 85.77 0.00e+00 1218.00
IUUC-Oga-088444 Otolemur garnettii 75.50 0.00e+00 1102.00
IUUC-Oar-089576 Ovis aries 74.09 0.00e+00 1026.00
IUUC-Ptr-090507 Pan troglodytes 80.73 0.00e+00 1393.00
IUUC-Pan-092325 Papio anubis 78.43 0.00e+00 1353.00
IUUC-Psi-094021 Pelodiscus sinensis 80.02 0.00e+00 1366.00
IUUC-Pma-094372 Petromyzon marinus 53.88 0.00e+00 721.00
IUUC-Pfo-096732 Poecilia formosa 93.98 0.00e+00 1681.00
IUUC-Pab-098426 Pongo abelii 65.61 0.00e+00 978.00
IUUC-Pca-100295 Procavia capensis 79.15 0.00e+00 1284.00
IUUC-Rno-105332 Rattus norvegicus 80.16 0.00e+00 1374.00
IUUC-Sha-106529 Sarcophilus harrisii 81.37 0.00e+00 1126.00
IUUC-Ssc-116176 Sus scrofa 79.05 0.00e+00 1249.00
IUUC-Tgu-116917 Taeniopygia guttata 81.10 0.00e+00 1264.00
IUUC-Tru-118398 Takifugu rubripes 90.22 0.00e+00 1143.00
IUUC-Tni-120819 Tetraodon nigroviridis 90.49 0.00e+00 1383.00
IUUC-Xtr-132747 Xenopus tropicalis 73.81 0.00e+00 1297.00
Created Date 25-Jun-2017

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