iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097581

Ensembl Protein ID

ENSPPYP00000000636.2

UniProt Accession

H2N4U7; H2N4U7_PONAB

Genbank Protein ID

ENSPPYP00000000636

Protein Name

DDB1- and CUL4-associated factor 6

Genbank Nucleotide ID

ABGA01036772

Gene Name

DCAF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000000545.2	ENSPPYT00000000661.2	ENSPPYP00000000636.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.00e-10	39.7	61	89

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgti 25
           gH + +++ +f    +d+ +vs+s+Dg+i
   Q: 61   GHRANIFSAKFlpctNDKQIVSCSGDGVI 89
           8************9777**********98 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSRGGSCPHL LWDVRKRSLG LEDPSRLRSR YLGRREFIQR LKLEATLNVH DGCVLTTIRS 60
GHRANIFSAK FLPCTNDKQI VSCSGDGVIF YTNVEQDAET NRQCQFTCHY GTTYEIMTVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTCGGG GTGGCTCCTG CCCACACCTG TTGTGGGACG TGAGGAAAAG GTCCCTCGGG 60
CTGGAGGACC CGTCCCGGCT GCGGAGTCGC TACCTGGGTG AGCGGGGGCC CCGGGGCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000048--IQ_motif_EF-hand-BS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50096--IQ
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0005634--C:nucleus
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001399	Ailuropoda melanoleuca	87.61	0.00e+00	794.00
IUUC-Apl-003181	Anas platyrhynchos	72.50	0.00e+00	1056.00
IUUC-Aca-004953	Anolis carolinensis	60.48	0.00e+00	971.00
IUUC-Ame-011314	Astyanax mexicanus	77.93	2.00e-171	596.00
IUUC-Bta-013552	Bos taurus	86.82	0.00e+00	1396.00
IUUC-Cja-019015	Callithrix jacchus	92.39	0.00e+00	793.00
IUUC-Cfa-021249	Canis familiaris	90.00	0.00e+00	759.00
IUUC-Cpo-021903	Cavia porcellus	87.61	0.00e+00	786.00
IUUC-Csa-023744	Chlorocebus sabaeus	92.61	0.00e+00	794.00
IUUC-Cho-024527	Choloepus hoffmanni	72.45	1.00e-153	536.00
IUUC-Dre-028040	Danio rerio	78.53	6.00e-171	594.00
IUUC-Dno-029777	Dasypus novemcinctus	90.22	0.00e+00	773.00
IUUC-Dor-030879	Dipodomys ordii	67.77	0.00e+00	954.00
IUUC-Ete-032607	Echinops telfairi	76.06	4.00e-139	488.00
IUUC-Eca-033396	Equus caballus	85.73	0.00e+00	1251.00
IUUC-Eeu-034944	Erinaceus europaeus	67.05	3.00e-138	486.00
IUUC-Fca-036020	Felis catus	83.56	0.00e+00	1319.00
IUUC-Fal-037527	Ficedula albicollis	67.12	0.00e+00	1001.00
IUUC-Gmo-039347	Gadus morhua	76.29	7.00e-164	571.00
IUUC-Gga-040564	Gallus gallus	70.79	0.00e+00	1075.00
IUUC-Gac-042029	Gasterosteus aculeatus	77.40	4.00e-167	582.00
IUUC-Ggo-045634	Gorilla gorilla	88.86	0.00e+00	637.00
IUUC-Hsa-045743	Homo sapiens	91.14	0.00e+00	1398.00
IUUC-Itr-048064	Ictidomys tridecemlineatus	84.32	0.00e+00	1280.00
IUUC-Lch-050457	Latimeria chalumnae	62.89	0.00e+00	978.00
IUUC-Loc-052880	Lepisosteus oculatus	79.55	2.00e-170	592.00
IUUC-Laf-053836	Loxodonta africana	83.48	0.00e+00	1054.00
IUUC-Mcc-055749	Macaca mulatta	92.61	0.00e+00	792.00
IUUC-Mga-059293	Meleagris gallopavo	68.34	0.00e+00	970.00
IUUC-Mmr-060923	Microcebus murinus	90.87	0.00e+00	787.00
IUUC-Mdo-063056	Monodelphis domestica	79.93	0.00e+00	1219.00
IUUC-Mmu-063121	Mus musculus	78.74	0.00e+00	1312.00
IUUC-Mpu-066035	Mustela putorius furo	84.76	0.00e+00	688.00
IUUC-Mlu-067903	Myotis lucifugus	81.19	0.00e+00	1255.00
IUUC-Nle-069415	Nomascus leucogenys	92.29	0.00e+00	746.00
IUUC-Opr-070809	Ochotona princeps	67.38	8.00e-129	454.00
IUUC-Ont-071470	Oreochromis niloticus	77.40	7.00e-167	580.00
IUUC-Oan-072748	Ornithorhynchus anatinus	89.85	4.00e-132	464.00
IUUC-Ocu-073865	Oryctolagus cuniculus	82.82	0.00e+00	1238.00
IUUC-Ola-086755	Oryzias latipes	76.27	2.00e-165	576.00
IUUC-Oga-088309	Otolemur garnettii	84.85	0.00e+00	717.00
IUUC-Oar-090264	Ovis aries	90.00	0.00e+00	790.00
IUUC-Ptr-090603	Pan troglodytes	93.04	0.00e+00	797.00
IUUC-Pan-092480	Papio anubis	89.15	0.00e+00	1412.00
IUUC-Psi-092973	Pelodiscus sinensis	76.02	0.00e+00	894.00
IUUC-Pno-095149	Phaeosphaeria nodorum	27.65	7.00e-18	86.30
IUUC-Pfo-096506	Poecilia formosa	76.84	2.00e-165	575.00
IUUC-Pca-100155	Procavia capensis	88.89	0.00e+00	750.00
IUUC-Pva-103022	Pteropus vampyrus	88.73	2.00e-180	626.00
IUUC-Rno-105851	Rattus norvegicus	75.63	0.00e+00	1292.00
IUUC-Sha-106790	Sarcophilus harrisii	72.80	0.00e+00	1138.00
IUUC-Ssc-115801	Sus scrofa	75.68	1.00e-101	362.00
IUUC-Tgu-116760	Taeniopygia guttata	71.83	0.00e+00	1011.00
IUUC-Tru-118422	Takifugu rubripes	76.84	2.00e-164	572.00
IUUC-Tni-120340	Tetraodon nigroviridis	76.86	4.00e-163	568.00
IUUC-Tbe-127997	Tupaia belangeri	70.88	0.00e+00	927.00
IUUC-Ttr-129311	Tursiops truncatus	77.92	0.00e+00	1233.00
IUUC-Vpa-130145	Vicugna pacos	88.99	0.00e+00	706.00
IUUC-Xtr-132496	Xenopus tropicalis	75.51	7.00e-174	603.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence