iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090609

UUCD1 version

UUC-PaT-01026

Ensembl Protein ID

ENSPTRP00000027688.3

UniProt Accession

H2QPJ4; H2QPJ4_PANTR

Genbank Protein ID

JAA04821.1; JAA20003.1; JAA25355.1; JAA43400.1

Protein Name

Ubiquitin-like modifier activating enzyme 6

Genbank Nucleotide ID

AACZ03034867; GABF01002142; GABD01007745; GABE01001339

Gene Name

UBA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000016099.3	ENSPTRT00000030000.3	ENSPTRP00000027688.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.90e-228	758.5	443	930

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G++ ++kl++ +++lvG+g++GcE+lKn++l+Gv      g+itv+D d +e+snlnrqFLfr+++++k+K+ +aa+a  +
   Q: 443  YDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVgtskekGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLK 531
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +n++++++ah +++++++e+i+   F++k d++++aldn+earr+v+++cl++ +pl++sgt+G++G+++vi+++lte+y++++dpp++
   Q: 532  INSQIKIDAHLNKVCPTTETIYndeFYTKQDIIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEE 620
           ***************************************************************************************** PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p+a+ehti+wa            +lfnk++++++++eevl+k++s +++eg+++v  +l s++++n+++++e+a+ +f+
   Q: 621  EIPFCTLKSFPAAIEHTIQWArdkfessfshkpSLFNKFWQTYSSAEEVLQKIQSGHSLEGCFQV-IKLLSRRPRNWSQCVELARLKFE 708
           *****************************************************************.999******************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k++++++ qll++f+ di+ k++s fw+                                                         +f++
   Q: 709  KYFNHKALQLLHCFPLDIRLKDGSLFWQspkrppspikfdlneplhlsflqnaaklyatvycipfteedlsadallnilsevkiqEFKP 797
           ***************************************************************************************** PP
   S: 279  naealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlike 360
            ++ +q++e++ k+ +v  +s++     ++l++++l++ ++k+++++++lsfekddd+  ++d++taa+nlra++++iep +d++++k+
   Q: 798  SNKVVQTDETARKPDHVPISSEDernaiFQLEKAILSNEATKSDLQMAVLSFEKDDDHngHIDFITAASNLRAKMYSIEP-ADRFKTKR 885
           ******************999999********************************************************.******** PP
   S: 361  iagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           iag+iipaiatt+a+v+Gl+a+E+iKv+ g +fe++kn+fl++a+
   Q: 886  IAGKIIPAIATTTATVSGLVALEMIKVTGGyPFEAYKNCFLNLAI 930
           *****************************************9886 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MEGSDPVAAH QREEASCSSW GTGSTNKNLP IMSTASVEID DALYSRQRYV LGDTAMQKMA 60
KSHVFLSGMG GLGLEIAKNL VLAGIKAVTI HDTEKCQAWD LGTNFFLSED DVVNKRNRAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTCCCGCCC CCTTCCTACC TTCCAGTAGC CGGCGGCGGT GTCTCAGGCG GCAATGGAAG 60
GATCCGATCC TGTGGCCGCC CATCAGCGGG AAGAGGCGTC CTGTTCTTCC TGGGGGACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019780--F:FAT10 activating enzyme activity
GO:0004839--F:ubiquitin activating enzyme activity
GO:0021764--P:amygdala development
GO:0060996--P:dendritic spine development
GO:0021766--P:hippocampus development
GO:0007612--P:learning
GO:0007626--P:locomotory behavior
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ptr:461294

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	40.80	0.00e+00	711.00
IUUC-Aml-001608	Ailuropoda melanoleuca	92.49	0.00e+00	2037.00
IUUC-Atr-002684	Amborella trichopoda	38.57	0.00e+00	680.00
IUUC-Apl-004158	Anas platyrhynchos	80.29	0.00e+00	1738.00
IUUC-Aca-005349	Anolis carolinensis	80.31	0.00e+00	1764.00
IUUC-Aly-005515	Arabidopsis lyrata	38.34	0.00e+00	701.00
IUUC-Ath-006891	Arabidopsis thaliana	39.01	0.00e+00	720.00
IUUC-Ago-007873	Ashbya gossypii	41.33	0.00e+00	688.00
IUUC-Acl-008181	Aspergillus clavatus	44.33	0.00e+00	699.00
IUUC-Afl-008455	Aspergillus flavus	43.53	0.00e+00	674.00
IUUC-Afu-009065	Aspergillus fumigatus	43.66	0.00e+00	703.00
IUUC-Ani-009371	Aspergillus nidulans	43.21	0.00e+00	672.00
IUUC-Ang-009737	Aspergillus niger	42.81	0.00e+00	679.00
IUUC-Aor-010007	Aspergillus oryzae	43.53	0.00e+00	674.00
IUUC-Ate-010466	Aspergillus terreus	42.74	0.00e+00	700.00
IUUC-Bgr-012281	Blumeria graminis	41.19	0.00e+00	678.00
IUUC-Bta-012696	Bos taurus	92.30	0.00e+00	2034.00
IUUC-Bci-013721	Botrytis cinerea	42.63	0.00e+00	665.00
IUUC-Bdi-014843	Brachypodium distachyon	39.30	0.00e+00	687.00
IUUC-Bol-015665	Brassica oleracea	37.98	0.00e+00	695.00
IUUC-Bra-017522	Brassica rapa	37.74	0.00e+00	684.00
IUUC-Cel-018260	Caenorhabditis elegans	38.46	5.00e-179	621.00
IUUC-Cja-019563	Callithrix jacchus	97.43	0.00e+00	2102.00
IUUC-Cfa-020951	Canis familiaris	92.40	0.00e+00	2042.00
IUUC-Cpo-022307	Cavia porcellus	88.30	0.00e+00	1932.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	38.91	2.00e-178	619.00
IUUC-Csa-023647	Chlorocebus sabaeus	98.29	0.00e+00	2132.00
IUUC-Cho-024682	Choloepus hoffmanni	77.25	0.00e+00	942.00
IUUC-Cin-025790	Ciona intestinalis	40.90	0.00e+00	751.00
IUUC-Csv-026084	Ciona savignyi	40.00	0.00e+00	725.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	42.87	0.00e+00	737.00
IUUC-Cne-026960	Cryptococcus neoformans	42.34	0.00e+00	687.00
IUUC-Cme-027290	Cyanidioschyzon merolae	35.54	1.00e-164	574.00
IUUC-Dre-028022	Danio rerio	66.73	0.00e+00	1469.00
IUUC-Dno-029796	Dasypus novemcinctus	90.86	0.00e+00	1951.00
IUUC-Dor-030981	Dipodomys ordii	76.09	0.00e+00	1521.00
IUUC-Dse-031524	Dothistroma septosporum	43.14	0.00e+00	694.00
IUUC-Dme-032045	Drosophila melanogaster	42.21	0.00e+00	737.00
IUUC-Ete-032514	Echinops telfairi	78.01	0.00e+00	1147.00
IUUC-Eca-033697	Equus caballus	92.91	0.00e+00	2004.00
IUUC-Eeu-035323	Erinaceus europaeus	84.28	0.00e+00	1366.00
IUUC-Fca-035858	Felis catus	93.88	0.00e+00	2024.00
IUUC-Fal-036848	Ficedula albicollis	80.22	0.00e+00	1733.00
IUUC-Fox-038007	Fusarium oxysporum	41.99	5.00e-100	358.00
IUUC-Fso-038339	Fusarium solani	42.70	0.00e+00	691.00
IUUC-Gmo-039326	Gadus morhua	65.95	0.00e+00	1384.00
IUUC-Ggr-039823	Gaeumannomyces graminis	42.96	0.00e+00	722.00
IUUC-Gga-040747	Gallus gallus	80.31	0.00e+00	1721.00
IUUC-Gac-041406	Gasterosteus aculeatus	66.73	0.00e+00	1389.00
IUUC-Gma-043198	Glycine max	38.37	0.00e+00	678.00
IUUC-Ggo-044577	Gorilla gorilla	99.53	0.00e+00	2156.00
IUUC-Hsa-046007	Homo sapiens	99.52	0.00e+00	2149.00
IUUC-Hvu-047846	Hordeum vulgare	39.70	0.00e+00	675.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	95.88	0.00e+00	1075.00
IUUC-Kpa-049112	Komagataella pastoris	41.22	0.00e+00	690.00
IUUC-Lch-049992	Latimeria chalumnae	73.27	0.00e+00	1543.00
IUUC-Lpe-051299	Leersia perrieri	39.21	0.00e+00	713.00
IUUC-Loc-051899	Lepisosteus oculatus	68.23	0.00e+00	1484.00
IUUC-Lma-053315	Leptosphaeria maculans	41.79	0.00e+00	727.00
IUUC-Laf-054413	Loxodonta africana	92.21	0.00e+00	1875.00
IUUC-Mcc-054656	Macaca mulatta	98.57	0.00e+00	2134.00
IUUC-Meu-056463	Macropus eugenii	71.52	0.00e+00	1425.00
IUUC-Mor-057269	Magnaporthe oryzae	42.43	0.00e+00	696.00
IUUC-Mpo-057435	Magnaporthe poae	42.83	0.00e+00	697.00
IUUC-Mtr-058572	Medicago truncatula	38.32	0.00e+00	664.00
IUUC-Mla-059176	Melampsora laricipopulina	42.31	0.00e+00	699.00
IUUC-Mga-059721	Meleagris gallopavo	78.99	0.00e+00	1627.00
IUUC-Mvi-060437	Microbotryum violaceum	39.77	0.00e+00	685.00
IUUC-Mmr-060908	Microcebus murinus	91.54	0.00e+00	2003.00
IUUC-Mdo-062096	Monodelphis domestica	84.39	0.00e+00	1895.00
IUUC-Mmu-064114	Mus musculus	89.16	0.00e+00	1955.00
IUUC-Mac-065505	Musa acuminata	38.73	0.00e+00	676.00
IUUC-Mpu-066017	Mustela putorius furo	92.49	0.00e+00	2049.00
IUUC-Mlu-068037	Myotis lucifugus	90.08	0.00e+00	1958.00
IUUC-Nfi-068407	Neosartorya fischeri	43.69	0.00e+00	691.00
IUUC-Ncr-068698	Neurospora crassa	43.34	0.00e+00	714.00
IUUC-Nle-069494	Nomascus leucogenys	98.38	0.00e+00	2131.00
IUUC-Opr-070910	Ochotona princeps	67.09	1.00e-174	607.00
IUUC-Ont-071592	Oreochromis niloticus	68.36	0.00e+00	1451.00
IUUC-Oan-073268	Ornithorhynchus anatinus	80.59	0.00e+00	1610.00
IUUC-Ocu-074296	Oryctolagus cuniculus	93.25	0.00e+00	2040.00
IUUC-Oba-075934	Oryza barthii	39.53	0.00e+00	716.00
IUUC-Obr-076557	Oryza brachyantha	40.83	0.00e+00	694.00
IUUC-Ogl-077762	Oryza glaberrima	39.53	0.00e+00	716.00
IUUC-Ogu-078305	Oryza glumaepatula	39.63	0.00e+00	717.00
IUUC-Oin-080154	Oryza indica	39.53	0.00e+00	716.00
IUUC-Olo-081089	Oryza longistaminata	39.73	0.00e+00	717.00
IUUC-Ome-081942	Oryza meridionalis	39.69	0.00e+00	699.00
IUUC-Oni-082447	Oryza nivara	39.63	0.00e+00	718.00
IUUC-Opu-083977	Oryza punctata	39.50	0.00e+00	705.00
IUUC-Oru-084469	Oryza rufipogon	39.63	0.00e+00	719.00
IUUC-Osa-085625	Oryza sativa	39.63	0.00e+00	717.00
IUUC-Ola-086376	Oryzias latipes	68.27	0.00e+00	1402.00
IUUC-Olu-087687	Ostreococcus lucimarinus	38.44	0.00e+00	641.00
IUUC-Oga-088186	Otolemur garnettii	93.63	0.00e+00	2044.00
IUUC-Oar-089307	Ovis aries	92.40	0.00e+00	2031.00
IUUC-Pan-092905	Papio anubis	98.32	0.00e+00	2034.00
IUUC-Psi-093489	Pelodiscus sinensis	81.39	0.00e+00	1753.00
IUUC-Pma-094203	Petromyzon marinus	64.86	1.00e-56	211.00
IUUC-Pno-095154	Phaeosphaeria nodorum	42.45	0.00e+00	734.00
IUUC-Ppa-095227	Physcomitrella patens	39.28	0.00e+00	665.00
IUUC-Pfo-096670	Poecilia formosa	68.59	0.00e+00	1456.00
IUUC-Pab-098418	Pongo abelii	98.67	0.00e+00	2130.00
IUUC-Pop-099550	Populus trichocarpa	38.62	0.00e+00	694.00
IUUC-Pca-100889	Procavia capensis	75.29	0.00e+00	1588.00
IUUC-Ppe-102012	Prunus persica	39.08	0.00e+00	702.00
IUUC-Pva-103144	Pteropus vampyrus	81.75	0.00e+00	1761.00
IUUC-Pgr-103336	Puccinia graminis	42.94	0.00e+00	674.00
IUUC-Ptt-103939	Puccinia triticina	43.14	0.00e+00	674.00
IUUC-Pte-104200	Pyrenophora teres	43.01	0.00e+00	736.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	43.44	0.00e+00	733.00
IUUC-Rno-105612	Rattus norvegicus	89.45	0.00e+00	1960.00
IUUC-Sce-106245	Saccharomyces cerevisiae	43.00	0.00e+00	732.00
IUUC-Sha-107388	Sarcophilus harrisii	86.32	0.00e+00	1879.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	41.84	0.00e+00	718.00
IUUC-Spo-108034	Schizosaccharomyces pombe	40.89	0.00e+00	687.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	42.37	0.00e+00	666.00
IUUC-Smo-108912	Selaginella moellendorffii	39.36	0.00e+00	669.00
IUUC-Sit-110281	Setaria italica	40.73	0.00e+00	715.00
IUUC-Sly-110914	Solanum lycopersicum	38.05	0.00e+00	689.00
IUUC-Stu-112109	Solanum tuberosum	38.24	0.00e+00	699.00
IUUC-Sar-113128	Sorex araneus	88.80	0.00e+00	1929.00
IUUC-Sbi-114089	Sorghum bicolor	40.40	0.00e+00	711.00
IUUC-Sre-115148	Sporisorium reilianum	41.90	0.00e+00	692.00
IUUC-Ssc-116117	Sus scrofa	93.07	0.00e+00	2048.00
IUUC-Tgu-116565	Taeniopygia guttata	80.63	0.00e+00	1745.00
IUUC-Tru-118591	Takifugu rubripes	66.76	0.00e+00	1413.00
IUUC-Tsy-119436	Tarsius syrichta	82.41	0.00e+00	1762.00
IUUC-Tni-120880	Tetraodon nigroviridis	66.34	0.00e+00	1401.00
IUUC-Tca-121436	Theobroma cacao	38.60	0.00e+00	701.00
IUUC-Tre-122009	Trichoderma reesei	43.20	0.00e+00	667.00
IUUC-Tvi-122259	Trichoderma virens	42.46	0.00e+00	678.00
IUUC-Tae-125628	Triticum aestivum	39.57	0.00e+00	679.00
IUUC-Tur-126330	Triticum urartu	40.90	0.00e+00	716.00
IUUC-Tme-127055	Tuber melanosporum	40.40	0.00e+00	636.00
IUUC-Tbe-127714	Tupaia belangeri	80.00	0.00e+00	1413.00
IUUC-Ttr-129159	Tursiops truncatus	80.51	0.00e+00	1710.00
IUUC-Uma-129387	Ustilago maydis	42.14	0.00e+00	697.00
IUUC-Vda-129977	Verticillium dahliae	42.12	0.00e+00	686.00
IUUC-Vpa-130716	Vicugna pacos	90.27	0.00e+00	1896.00
IUUC-Vvi-130857	Vitis vinifera	38.72	0.00e+00	695.00
IUUC-Xtr-132947	Xenopus tropicalis	70.24	0.00e+00	1531.00
IUUC-Xma-133494	Xiphophorus maculatus	68.69	0.00e+00	1451.00
IUUC-Yli-134547	Yarrowia lipolytica	41.99	0.00e+00	716.00
IUUC-Zma-134970	Zea mays	38.50	0.00e+00	712.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence