iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000009388.4	ENSXETT00000020687.3	ENSXETP00000020687.3
ENSXETG00000009388.4	ENSXETT00000020685.4	ENSXETP00000020685.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.20e-61	199.2	619	652
UBD/Beta-Prp	4.10e-102	341.5	370	652

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H++ vtcl+f+ ++++++sdDgt+k+WDl+tg  
   Q: 619  HQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEF 652
           9*********449******************976 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk 91
           k+lkgh+++vitc++f   ++ +++gs+d+t+kvw++ tgk+lr+l gh+++v++ ++ ++  i+++gs+Drt+kvw+ +tg+c+htl 
   Q: 370  KVLKGHDDHVITCLQF--CGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDN--IIISGSTDRTLKVWNAETGECIHTLY 454
           6799************..*******************************************..************************** PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           gh+++v+++++++  +++vsGs+d t+rvwd+etgqcl+ +l gh ++v+cv++++  + +vsG++D +v++Wd +t+++l+tl+g ht
   Q: 455  GHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLH-VLMGHVAAVRCVQYDG--RRVVSGAYDFMVKVWDPETETCLHTLQG-HT 537
           *************..************************.****************..***************************9.** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvis 269
           ++vysl+fd    ++vsgsld+++++wd++tg+c++tl+gh++ ++ +++   d++lvsg++D +++iWd+++g++l+tlq++n++ ++
   Q: 538  NRVYSLQFDG--IHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSA 622
           *********9..9**************************************..************************************ PP
   S: 270  vavlsfgdnvlvlgsedskvniwklkknep 299
           v++l+f++n +++ s+d++v++w+lk+ e+
   Q: 623  VTCLQFNKNFVITSSDDGTVKLWDLKTGEF 652
           *************************98776 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MNQELLSVGS KRRRTGGSVR GNASSSQADE EQMNRVVEEE EQQQVELNGE IDEDAPGSLE 60
RNETHQEHLE ENNNSCTIAD QESADQPGDH EHSQQDEDED EDQACDAEDE DEEEMDQDSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGTAGC AAGCTGGCTT TTGGAAATGA ATCAGGAACT GCTGTCTGTG GGCAGCAAGA 60
GACGACGGAC TGGCGGTTCT GTACGAGGTA ATGCTTCGTC CAGCCAAGCA GATGAGGAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0001525--P:angiogenesis
GO:0031642--P:negative regulation of myelination
GO:0045746--P:negative regulation of Notch signaling pathway
GO:0032006--P:regulation of TOR signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002406	Ailuropoda melanoleuca	96.24	0.00e+00	1102.00
IUUC-Apl-003489	Anas platyrhynchos	86.40	0.00e+00	1149.00
IUUC-Aca-005318	Anolis carolinensis	97.97	0.00e+00	1088.00
IUUC-Ago-007794	Ashbya gossypii	30.72	1.00e-60	227.00
IUUC-Acl-008123	Aspergillus clavatus	33.53	2.00e-76	280.00
IUUC-Afl-008730	Aspergillus flavus	32.30	2.00e-74	274.00
IUUC-Afu-009014	Aspergillus fumigatus	33.47	3.00e-77	282.00
IUUC-Ani-009332	Aspergillus nidulans	34.26	2.00e-81	296.00
IUUC-Ang-009790	Aspergillus niger	31.96	2.00e-78	286.00
IUUC-Aor-010215	Aspergillus oryzae	31.50	4.00e-76	279.00
IUUC-Ate-010535	Aspergillus terreus	32.61	8.00e-78	284.00
IUUC-Ame-010898	Astyanax mexicanus	92.77	0.00e+00	1043.00
IUUC-Bgr-012075	Blumeria graminis	33.79	1.00e-76	280.00
IUUC-Bta-012391	Bos taurus	98.34	0.00e+00	1088.00
IUUC-Bci-013725	Botrytis cinerea	33.53	3.00e-80	292.00
IUUC-Cel-018495	Caenorhabditis elegans	48.43	6.00e-131	461.00
IUUC-Cja-018902	Callithrix jacchus	96.94	0.00e+00	1101.00
IUUC-Cfa-020237	Canis familiaris	96.60	0.00e+00	1102.00
IUUC-Cpo-022234	Cavia porcellus	98.34	0.00e+00	1090.00
IUUC-Cre-022837	Chlamydomonas reinhardtii	37.54	7.00e-49	187.00
IUUC-Csa-023532	Chlorocebus sabaeus	96.76	0.00e+00	1102.00
IUUC-Cho-025026	Choloepus hoffmanni	80.43	0.00e+00	737.00
IUUC-Cin-025516	Ciona intestinalis	70.68	4.00e-141	493.00
IUUC-Csv-026312	Ciona savignyi	75.26	0.00e+00	755.00
IUUC-Cgl-026492	Colletotrichum gloeosporioides	35.43	8.00e-87	314.00
IUUC-Cne-027018	Cryptococcus neoformans	33.46	4.00e-74	273.00
IUUC-Cme-027168	Cyanidioschyzon merolae	31.10	2.00e-31	130.00
IUUC-Dre-028303	Danio rerio	92.98	0.00e+00	1041.00
IUUC-Dno-029576	Dasypus novemcinctus	94.63	0.00e+00	1084.00
IUUC-Dor-030196	Dipodomys ordii	84.71	0.00e+00	1115.00
IUUC-Dse-031558	Dothistroma septosporum	38.98	7.00e-71	261.00
IUUC-Dme-031702	Drosophila melanogaster	76.01	0.00e+00	798.00
IUUC-Ete-032791	Echinops telfairi	89.26	0.00e+00	989.00
IUUC-Eca-033424	Equus caballus	98.34	0.00e+00	1089.00
IUUC-Eeu-034996	Erinaceus europaeus	93.53	0.00e+00	1061.00
IUUC-Fca-036422	Felis catus	96.60	0.00e+00	1104.00
IUUC-Fal-037267	Ficedula albicollis	95.16	0.00e+00	1086.00
IUUC-Fox-037800	Fusarium oxysporum	34.47	2.00e-86	313.00
IUUC-Fso-038258	Fusarium solani	34.88	1.00e-85	310.00
IUUC-Gmo-039119	Gadus morhua	84.47	0.00e+00	902.00
IUUC-Ggr-039781	Gaeumannomyces graminis	34.86	3.00e-86	312.00
IUUC-Gga-040667	Gallus gallus	88.70	0.00e+00	1154.00
IUUC-Gac-042423	Gasterosteus aculeatus	75.28	0.00e+00	807.00
IUUC-Ggo-044422	Gorilla gorilla	96.60	0.00e+00	1104.00
IUUC-Hsa-045898	Homo sapiens	96.42	0.00e+00	1104.00
IUUC-Itr-048241	Ictidomys tridecemlineatus	98.08	0.00e+00	962.00
IUUC-Kpa-049097	Komagataella pastoris	31.15	1.00e-75	278.00
IUUC-Lch-050414	Latimeria chalumnae	93.64	0.00e+00	1086.00
IUUC-Loc-052348	Lepisosteus oculatus	96.49	0.00e+00	1068.00
IUUC-Lma-053185	Leptosphaeria maculans	32.80	8.00e-73	268.00
IUUC-Laf-054054	Loxodonta africana	96.76	0.00e+00	1102.00
IUUC-Mcc-055056	Macaca mulatta	96.76	0.00e+00	1102.00
IUUC-Meu-056778	Macropus eugenii	93.23	4.00e-179	621.00
IUUC-Mor-057133	Magnaporthe oryzae	39.13	2.00e-74	273.00
IUUC-Mpo-057542	Magnaporthe poae	39.13	2.00e-74	273.00
IUUC-Mla-059081	Melampsora laricipopulina	34.86	6.00e-82	298.00
IUUC-Mga-059255	Meleagris gallopavo	94.91	0.00e+00	1112.00
IUUC-Mvi-060490	Microbotryum violaceum	38.75	3.00e-67	250.00
IUUC-Mmr-061292	Microcebus murinus	96.94	0.00e+00	1100.00
IUUC-Mdo-062304	Monodelphis domestica	96.42	0.00e+00	1108.00
IUUC-Mmu-063610	Mus musculus	85.67	0.00e+00	1156.00
IUUC-Mpu-065931	Mustela putorius furo	96.42	0.00e+00	1101.00
IUUC-Mlu-066976	Myotis lucifugus	87.66	0.00e+00	1152.00
IUUC-Nfi-068428	Neosartorya fischeri	32.87	7.00e-78	285.00
IUUC-Ncr-068688	Neurospora crassa	36.38	2.00e-88	320.00
IUUC-Nle-070174	Nomascus leucogenys	96.42	0.00e+00	1104.00
IUUC-Opr-070851	Ochotona princeps	84.47	0.00e+00	640.00
IUUC-Ont-071997	Oreochromis niloticus	94.82	0.00e+00	1072.00
IUUC-Oan-072936	Ornithorhynchus anatinus	88.03	0.00e+00	1161.00
IUUC-Ocu-074742	Oryctolagus cuniculus	96.76	0.00e+00	1100.00
IUUC-Obr-076806	Oryza brachyantha	31.52	9.00e-30	125.00
IUUC-Oin-079809	Oryza indica	31.52	7.00e-30	126.00
IUUC-Ola-087098	Oryzias latipes	94.09	0.00e+00	1060.00
IUUC-Olu-087837	Ostreococcus lucimarinus	34.47	4.00e-38	151.00
IUUC-Oga-088884	Otolemur garnettii	98.68	0.00e+00	778.00
IUUC-Oar-090220	Ovis aries	94.94	0.00e+00	1108.00
IUUC-Ptr-090492	Pan troglodytes	96.42	0.00e+00	1104.00
IUUC-Pan-091770	Papio anubis	96.76	0.00e+00	1102.00
IUUC-Psi-093207	Pelodiscus sinensis	98.34	0.00e+00	1090.00
IUUC-Pma-094749	Petromyzon marinus	83.49	0.00e+00	946.00
IUUC-Pno-095026	Phaeosphaeria nodorum	38.83	4.00e-71	263.00
IUUC-Pfo-096493	Poecilia formosa	95.38	0.00e+00	1060.00
IUUC-Pab-098141	Pongo abelii	98.34	0.00e+00	1088.00
IUUC-Pca-100571	Procavia capensis	94.70	0.00e+00	775.00
IUUC-Pva-102988	Pteropus vampyrus	97.12	0.00e+00	1107.00
IUUC-Pgr-103612	Puccinia graminis	35.66	2.00e-62	233.00
IUUC-Ptt-103698	Puccinia triticina	35.55	7.00e-42	165.00
IUUC-Pte-104275	Pyrenophora teres	32.36	1.00e-74	274.00
IUUC-Pyt-104438	Pyrenophora triticirepentis	33.91	7.00e-79	288.00
IUUC-Rno-105706	Rattus norvegicus	86.68	0.00e+00	1157.00
IUUC-Sce-106343	Saccharomyces cerevisiae	31.29	7.00e-61	228.00
IUUC-Sha-107653	Sarcophilus harrisii	87.94	0.00e+00	1155.00
IUUC-Sja-107840	Schizosaccharomyces japonicus	33.33	1.00e-78	287.00
IUUC-Spo-108115	Schizosaccharomyces pombe	32.14	5.00e-63	235.00
IUUC-Sar-113600	Sorex araneus	90.47	0.00e+00	1008.00
IUUC-Sre-114901	Sporisorium reilianum	48.13	1.00e-67	252.00
IUUC-Ssc-115787	Sus scrofa	95.14	0.00e+00	1073.00
IUUC-Tgu-117510	Taeniopygia guttata	88.06	0.00e+00	1145.00
IUUC-Tru-117819	Takifugu rubripes	92.91	0.00e+00	1097.00
IUUC-Tsy-118828	Tarsius syrichta	88.08	0.00e+00	1135.00
IUUC-Tni-120468	Tetraodon nigroviridis	95.19	0.00e+00	1074.00
IUUC-Tre-122193	Trichoderma reesei	36.67	1.00e-86	314.00
IUUC-Tvi-122615	Trichoderma virens	35.44	1.00e-84	306.00
IUUC-Tme-127021	Tuber melanosporum	35.29	9.00e-86	310.00
IUUC-Tbe-127925	Tupaia belangeri	98.33	0.00e+00	1089.00
IUUC-Ttr-128899	Tursiops truncatus	96.58	0.00e+00	1099.00
IUUC-Uma-129449	Ustilago maydis	46.89	7.00e-67	249.00
IUUC-Vda-129802	Verticillium dahliae	36.81	3.00e-89	322.00
IUUC-Vpa-130082	Vicugna pacos	96.36	0.00e+00	922.00
IUUC-Xma-133646	Xiphophorus maculatus	95.20	0.00e+00	1055.00
IUUC-Yli-134429	Yarrowia lipolytica	34.55	2.00e-86	312.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence