iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067233

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02027871

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000001985.2	ENSMLUT00000001991.2	ENSMLUP00000001812.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.10e-73	246.9	89	421
ULD/UDP/UBQ/UBQ_Other	5.70e-11	42.2	955	1017

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp..........kepkgellkslqklfeelwkskkkavsprellkalkk 79
           +Gl+Nlg+tCY+N  LQ+ +   elr++l    ++++++  +          + + ++++++lq lf+ l++s++++++p+ ++kal+ 
   Q: 89   VGLTNLGATCYVNTFLQVWFLNLELRQALYL-CPSTCSDYMRgdgiqeekeiDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALG- 175
           6*****************************9.7777776666666655555566777******************************9. PP
   S: 80   eaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
               +++ +qqDaqEf + +++ le++l                       +++k+   ++++++ F g++   ++c++c+++s+  ++
   Q: 176  ----LDTGQQQDAQEFSKLFMSLLEDTL-----------------------SKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSK 237
           ....78899*******************.......................457889999***************************** PP
   S: 169  fldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpl 257
           f++l+l+++g++     +l+dc+++f kee+leg+n+y+ce+c++kq+a++k++l +lP +L l+L+Rf f++++++++k+n+++ f +
   Q: 238  FYELELNIQGHK-----QLTDCISEFLKEERLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSE 321
           ************.....9**********************************************************************9 PP
   S: 258  eLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg................. 327
            Ld++p+++++      ++ YeL+av++H G s+ sGHY+a+vk+ ++g+W++f+D+ +++++ ++ +   +                 
   Q: 322  LLDMEPYVEHKGG----SYVYELSAVLIHRGvSAYSGHYIAHVKDpQSGEWYKFNDEDIEKMEGKKLQLGIEedlaepsksqtrkpkcg 406
           9*******99554....79**************************44555************9999998665999************** PP
   S: 328  ......staYvlfYk 336
                 ++aY+l+Y+
   Q: 407  kgthcsRNAYMLVYR 421
           **************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   k...vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           k   v+   t +eLK +i +++++ p +q+L ++GkiL +d+ tL+ +g+ ++s+i+l  +++
   Q: 955  KallVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILtDDGATLGTLGVIPESVILLKADEP 1017
           344489999************************************************988775 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MAPRLQLEKA AWRWAETVRP EEVSQEHIET AYRIWLEPCI RGVCRRNCKG NPNCLVGIGE 60
HIWLGEIDEN SFHNIDDPNC ERRKKNSFVG LTNLGATCYV NTFLQVWFLN LELRQALYLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCCGC GGCTGCAGCT GGAGAAGGCC GCCTGGCGCT GGGCGGAGAC GGTGCGGCCC 60
GAGGAGGTGT CGCAGGAGCA CATCGAGACC GCCTACCGCA TCTGGCTGGA GCCTTGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	32.15	1.00e-78	288.00
IUUC-Aml-001357	Ailuropoda melanoleuca	96.94	0.00e+00	2036.00
IUUC-Atr-002976	Amborella trichopoda	31.82	9.00e-77	281.00
IUUC-Apl-003773	Anas platyrhynchos	87.03	0.00e+00	1678.00
IUUC-Aca-004466	Anolis carolinensis	80.75	0.00e+00	868.00
IUUC-Aly-006249	Arabidopsis lyrata	29.86	1.00e-70	261.00
IUUC-Ath-006700	Arabidopsis thaliana	30.84	1.00e-78	288.00
IUUC-Ame-011554	Astyanax mexicanus	67.85	0.00e+00	1435.00
IUUC-Bta-012573	Bos taurus	96.17	0.00e+00	2049.00
IUUC-Bdi-014149	Brachypodium distachyon	32.28	3.00e-80	293.00
IUUC-Bol-016289	Brassica oleracea	31.92	4.00e-77	283.00
IUUC-Bra-017494	Brassica rapa	32.24	7.00e-81	295.00
IUUC-Cel-018662	Caenorhabditis elegans	27.35	5.00e-29	124.00
IUUC-Cja-019991	Callithrix jacchus	95.74	0.00e+00	2048.00
IUUC-Cfa-020294	Canis familiaris	97.03	0.00e+00	2079.00
IUUC-Cpo-021706	Cavia porcellus	93.81	0.00e+00	1921.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	30.91	2.00e-43	172.00
IUUC-Csa-023931	Chlorocebus sabaeus	96.75	0.00e+00	2057.00
IUUC-Cho-024566	Choloepus hoffmanni	97.11	4.00e-159	555.00
IUUC-Cin-025307	Ciona intestinalis	46.51	2.00e-75	275.00
IUUC-Csv-026006	Ciona savignyi	36.53	8.00e-149	521.00
IUUC-Cne-027065	Cryptococcus neoformans	28.16	3.00e-68	253.00
IUUC-Dre-027624	Danio rerio	68.52	0.00e+00	1479.00
IUUC-Dno-029633	Dasypus novemcinctus	96.31	0.00e+00	1305.00
IUUC-Dor-030809	Dipodomys ordii	74.29	0.00e+00	1196.00
IUUC-Ete-032818	Echinops telfairi	91.14	0.00e+00	952.00
IUUC-Eca-033692	Equus caballus	97.03	0.00e+00	2062.00
IUUC-Eeu-035185	Erinaceus europaeus	74.42	0.00e+00	796.00
IUUC-Fca-035676	Felis catus	96.65	0.00e+00	2070.00
IUUC-Fal-036913	Ficedula albicollis	86.33	0.00e+00	1826.00
IUUC-Gmo-038532	Gadus morhua	64.77	0.00e+00	1384.00
IUUC-Gga-041041	Gallus gallus	86.42	0.00e+00	1817.00
IUUC-Gac-042570	Gasterosteus aculeatus	65.93	0.00e+00	1422.00
IUUC-Gma-044136	Glycine max	27.22	8.00e-93	335.00
IUUC-Ggo-045367	Gorilla gorilla	91.98	0.00e+00	1920.00
IUUC-Hsa-046019	Homo sapiens	97.03	0.00e+00	2063.00
IUUC-Hvu-047303	Hordeum vulgare	33.64	3.00e-65	243.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	93.98	0.00e+00	2029.00
IUUC-Lch-049989	Latimeria chalumnae	75.47	0.00e+00	1628.00
IUUC-Lpe-051612	Leersia perrieri	32.40	7.00e-78	285.00
IUUC-Loc-052756	Lepisosteus oculatus	70.19	0.00e+00	1540.00
IUUC-Laf-054043	Loxodonta africana	95.48	0.00e+00	2053.00
IUUC-Mcc-054986	Macaca mulatta	95.56	0.00e+00	2045.00
IUUC-Meu-056228	Macropus eugenii	76.95	0.00e+00	866.00
IUUC-Mtr-058762	Medicago truncatula	29.60	4.00e-86	313.00
IUUC-Mga-059896	Meleagris gallopavo	86.03	0.00e+00	1724.00
IUUC-Mvi-060269	Microbotryum violaceum	37.11	4.00e-62	233.00
IUUC-Mmr-060887	Microcebus murinus	97.13	0.00e+00	2064.00
IUUC-Mdo-062506	Monodelphis domestica	92.63	0.00e+00	1986.00
IUUC-Mmu-063642	Mus musculus	91.44	0.00e+00	1979.00
IUUC-Mac-064896	Musa acuminata	31.45	5.00e-75	276.00
IUUC-Mpu-066194	Mustela putorius furo	96.84	0.00e+00	2053.00
IUUC-Nle-069052	Nomascus leucogenys	96.02	0.00e+00	2054.00
IUUC-Opr-070890	Ochotona princeps	93.25	0.00e+00	1238.00
IUUC-Ont-071450	Oreochromis niloticus	64.18	0.00e+00	1361.00
IUUC-Oan-073252	Ornithorhynchus anatinus	89.19	0.00e+00	1056.00
IUUC-Ocu-073796	Oryctolagus cuniculus	95.53	0.00e+00	1746.00
IUUC-Oba-075563	Oryza barthii	31.69	9.00e-79	288.00
IUUC-Obr-076394	Oryza brachyantha	31.93	6.00e-79	289.00
IUUC-Ogl-077339	Oryza glaberrima	38.31	9.00e-41	160.00
IUUC-Ogu-079007	Oryza glumaepatula	32.93	3.00e-74	273.00
IUUC-Oin-079997	Oryza indica	31.69	4.00e-79	289.00
IUUC-Olo-080364	Oryza longistaminata	31.69	1.00e-78	288.00
IUUC-Ome-081165	Oryza meridionalis	32.93	9.00e-75	275.00
IUUC-Oni-083026	Oryza nivara	31.69	5.00e-79	289.00
IUUC-Opu-083284	Oryza punctata	33.74	2.00e-74	274.00
IUUC-Oru-084797	Oryza rufipogon	31.69	5.00e-79	289.00
IUUC-Osa-086221	Oryza sativa	38.31	9.00e-41	160.00
IUUC-Ola-086568	Oryzias latipes	66.05	0.00e+00	1426.00
IUUC-Oga-088687	Otolemur garnettii	95.17	0.00e+00	2040.00
IUUC-Oar-090345	Ovis aries	96.40	0.00e+00	1962.00
IUUC-Ptr-090734	Pan troglodytes	96.84	0.00e+00	2061.00
IUUC-Pan-091704	Papio anubis	93.04	0.00e+00	1960.00
IUUC-Psi-092937	Pelodiscus sinensis	86.70	0.00e+00	1595.00
IUUC-Ppa-095808	Physcomitrella patens	27.17	8.00e-66	246.00
IUUC-Pab-098129	Pongo abelii	96.94	0.00e+00	2062.00
IUUC-Pop-099738	Populus trichocarpa	27.10	2.00e-77	284.00
IUUC-Pca-100647	Procavia capensis	97.29	0.00e+00	683.00
IUUC-Ppe-102091	Prunus persica	32.72	1.00e-81	298.00
IUUC-Pva-102719	Pteropus vampyrus	96.84	0.00e+00	2050.00
IUUC-Rno-105363	Rattus norvegicus	93.30	0.00e+00	2004.00
IUUC-Sha-107620	Sarcophilus harrisii	89.64	0.00e+00	1855.00
IUUC-Smo-109487	Selaginella moellendorffii	27.66	6.00e-82	299.00
IUUC-Sit-110683	Setaria italica	32.61	6.00e-80	292.00
IUUC-Sly-111377	Solanum lycopersicum	30.62	4.00e-78	286.00
IUUC-Stu-111969	Solanum tuberosum	31.68	3.00e-70	259.00
IUUC-Sar-113099	Sorex araneus	95.03	0.00e+00	1720.00
IUUC-Sbi-113833	Sorghum bicolor	42.19	1.00e-56	213.00
IUUC-Ssc-115279	Sus scrofa	90.00	0.00e+00	1357.00
IUUC-Tgu-117519	Taeniopygia guttata	83.70	0.00e+00	1673.00
IUUC-Tru-117651	Takifugu rubripes	65.08	0.00e+00	1405.00
IUUC-Tsy-119201	Tarsius syrichta	92.90	0.00e+00	1796.00
IUUC-Tni-120840	Tetraodon nigroviridis	66.26	0.00e+00	1431.00
IUUC-Tca-121674	Theobroma cacao	31.36	7.00e-83	302.00
IUUC-Tae-125247	Triticum aestivum	26.10	3.00e-80	293.00
IUUC-Tur-126599	Triticum urartu	32.50	6.00e-78	286.00
IUUC-Tbe-127782	Tupaia belangeri	88.07	0.00e+00	1167.00
IUUC-Ttr-128312	Tursiops truncatus	95.50	0.00e+00	2020.00
IUUC-Vpa-130348	Vicugna pacos	96.70	0.00e+00	1956.00
IUUC-Vvi-131353	Vitis vinifera	31.70	4.00e-81	296.00
IUUC-Xtr-132172	Xenopus tropicalis	69.73	0.00e+00	1340.00
IUUC-Xma-133263	Xiphophorus maculatus	67.36	0.00e+00	1397.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence