iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028214

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

WD repeat domain 37

Genbank Nucleotide ID

AL954666

Gene Name

wdr37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000074611.4	ENSDART00000134598.2	ENSDARP00000114888.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-24	85.9	365	396
UBD/Beta-Prp	3.50e-46	158.6	276	486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 365  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 396
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtl 90
           tlk+ h++v+ + ++  ++++++t+s+d+   ++dv+t  l+++l gh++e t ++ +p++ + vt+s+D t ++wd++++++  v ++
   Q: 276  TLKS-HQGVVIAADWLVGGKQVVTASWDRAANLYDVETSELVHTLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVF 363
           4444.5556666999999*************************************************************665422889* PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtlt 176
           +gh+d+v+s  f   gd +vsGs+drt++vwdl++          +d++vn ++v+ ++++++  +++r+vrl+d+   + ++l r  +
   Q: 364  QGHTDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPI-ATIRTDSAVNRISVSANQRIIALPHDNRQVRLFDMngvRLARLPRSNR 450
           *********99999.********************99987.7788899****************************7778888888888 PP
   S: 177  gghtdsvyslsfdsng..kelvsgsldgtvklwdlq 210
           +gh ++v + +++++     l +++ d++ + w++ 
   Q: 451  QGHRRMVCCSAWNEENqaCNLFTCGFDRQAIGWNIN 486
           88**********99994556799**********986 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MPVESGNSAA ARQVKQKRKS HSLSIRRTNS TEQDRTGMQR DMLEGQDSKL PMALRSNLLD 60
LFGQIEREFE NLYIENLELR REIESLNERL SGEGQTVEGG DLSKGALKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTGGGACT TTTATTTTGA AGTTTTACAT CCGGTCGTAT CTGTTATCAT TTCCCCTTGC 60
TTCACAGTCT GCCGATAGTG TCGGGATTGA TCAAAAACAC ATCAAAGTGT GAACATCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0000460--P:maturation of 5.8S rRNA
GO:0000470--P:maturation of LSU-rRNA

KEGG

dre:558075

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	82.66	0.00e+00	842.00
IUUC-Apl-003647	Anas platyrhynchos	85.45	0.00e+00	860.00
IUUC-Aca-004759	Anolis carolinensis	85.45	0.00e+00	860.00
IUUC-Ame-011103	Astyanax mexicanus	62.50	9.00e-163	566.00
IUUC-Bta-012718	Bos taurus	83.67	0.00e+00	846.00
IUUC-Cel-018499	Caenorhabditis elegans	40.61	1.00e-92	333.00
IUUC-Cja-019492	Callithrix jacchus	83.43	0.00e+00	857.00
IUUC-Cfa-020199	Canis familiaris	82.86	0.00e+00	856.00
IUUC-Cpo-022500	Cavia porcellus	76.81	0.00e+00	800.00
IUUC-Csa-023567	Chlorocebus sabaeus	84.24	0.00e+00	864.00
IUUC-Cho-025071	Choloepus hoffmanni	58.91	1.00e-154	540.00
IUUC-Cin-025460	Ciona intestinalis	44.47	4.00e-102	365.00
IUUC-Csv-026042	Ciona savignyi	46.83	2.00e-107	382.00
IUUC-Dno-029826	Dasypus novemcinctus	84.82	0.00e+00	730.00
IUUC-Dor-030967	Dipodomys ordii	84.04	0.00e+00	781.00
IUUC-Dme-031936	Drosophila melanogaster	49.04	8.00e-118	417.00
IUUC-Ete-032452	Echinops telfairi	81.58	0.00e+00	836.00
IUUC-Eca-033278	Equus caballus	83.27	0.00e+00	860.00
IUUC-Eeu-034592	Erinaceus europaeus	71.46	0.00e+00	706.00
IUUC-Fca-036431	Felis catus	83.10	0.00e+00	856.00
IUUC-Fal-037149	Ficedula albicollis	85.45	0.00e+00	860.00
IUUC-Gmo-038476	Gadus morhua	86.97	0.00e+00	836.00
IUUC-Gga-041099	Gallus gallus	85.05	0.00e+00	859.00
IUUC-Gac-042374	Gasterosteus aculeatus	88.60	0.00e+00	859.00
IUUC-Ggo-044683	Gorilla gorilla	78.54	0.00e+00	794.00
IUUC-Hsa-046658	Homo sapiens	84.01	0.00e+00	867.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	84.18	0.00e+00	801.00
IUUC-Lch-050571	Latimeria chalumnae	82.13	0.00e+00	837.00
IUUC-Loc-052652	Lepisosteus oculatus	84.67	0.00e+00	864.00
IUUC-Laf-053712	Loxodonta africana	82.97	0.00e+00	851.00
IUUC-Mcc-055521	Macaca mulatta	84.24	0.00e+00	864.00
IUUC-Meu-056324	Macropus eugenii	81.17	0.00e+00	806.00
IUUC-Mga-060114	Meleagris gallopavo	84.88	0.00e+00	859.00
IUUC-Mmr-061176	Microcebus murinus	83.84	0.00e+00	861.00
IUUC-Mdo-061888	Monodelphis domestica	85.08	0.00e+00	840.00
IUUC-Mmu-063977	Mus musculus	83.87	0.00e+00	871.00
IUUC-Mpu-066220	Mustela putorius furo	70.86	2.00e-149	521.00
IUUC-Mlu-068155	Myotis lucifugus	83.87	0.00e+00	866.00
IUUC-Nle-069964	Nomascus leucogenys	83.84	0.00e+00	861.00
IUUC-Opr-070925	Ochotona princeps	79.93	3.00e-124	438.00
IUUC-Ont-071317	Oreochromis niloticus	91.33	0.00e+00	867.00
IUUC-Oan-072952	Ornithorhynchus anatinus	85.48	0.00e+00	866.00
IUUC-Ocu-073913	Oryctolagus cuniculus	83.27	0.00e+00	863.00
IUUC-Ola-087024	Oryzias latipes	87.93	0.00e+00	894.00
IUUC-Oga-087945	Otolemur garnettii	82.86	0.00e+00	863.00
IUUC-Oar-089854	Ovis aries	84.07	0.00e+00	842.00
IUUC-Ptr-091486	Pan troglodytes	84.21	0.00e+00	868.00
IUUC-Pan-091738	Papio anubis	84.24	0.00e+00	864.00
IUUC-Psi-093953	Pelodiscus sinensis	84.68	0.00e+00	856.00
IUUC-Pma-094560	Petromyzon marinus	73.07	0.00e+00	766.00
IUUC-Pfo-097222	Poecilia formosa	88.46	0.00e+00	867.00
IUUC-Pab-098778	Pongo abelii	79.55	0.00e+00	812.00
IUUC-Pca-100852	Procavia capensis	80.77	0.00e+00	813.00
IUUC-Pva-103130	Pteropus vampyrus	80.99	5.00e-118	417.00
IUUC-Rno-105848	Rattus norvegicus	76.21	0.00e+00	763.00
IUUC-Sha-106750	Sarcophilus harrisii	85.08	0.00e+00	860.00
IUUC-Sar-113749	Sorex araneus	76.52	0.00e+00	773.00
IUUC-Ssc-115691	Sus scrofa	83.23	0.00e+00	828.00
IUUC-Tgu-117365	Taeniopygia guttata	84.85	0.00e+00	817.00
IUUC-Tru-117595	Takifugu rubripes	87.90	0.00e+00	865.00
IUUC-Tsy-118973	Tarsius syrichta	65.75	4.00e-128	451.00
IUUC-Tni-120545	Tetraodon nigroviridis	86.35	0.00e+00	880.00
IUUC-Tbe-127976	Tupaia belangeri	63.36	4.00e-173	601.00
IUUC-Ttr-128472	Tursiops truncatus	81.17	0.00e+00	828.00
IUUC-Xtr-132621	Xenopus tropicalis	85.05	0.00e+00	833.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence