iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060114

UUCD1 version

UUC-MeG-00744

Ensembl Protein ID

ENSMGAP00000019046.1

UniProt Accession

G3UTJ8; G3UTJ8_MELGA

Protein Name

Uncharacterized protein

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000005536.2	ENSMGAT00000020069.1	ENSMGAP00000019046.1
ENSMGAG00000005536.2	ENSMGAT00000006197.1	ENSMGAP00000005464.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-23	80.2	367	398
UBD/Beta-Prp	3.50e-45	154.2	280	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 367  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 398
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 280  KSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 368
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++          +d++vn ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 369  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPI-ATIRTDSAVNRINVCVGQRIIALPHDNRQVRLFDMsgvRLARLPRSNRQGH 455
           ******99999.********************99887.555556666767666669*****************777778888888888* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 456  RRMVCCSAWSEDHpiCNLFTCGFDRQAIGWNIN 488
           ************9777899***********986 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MPIESGSCAS ARQAKQKRKS HSLSIRRTNS SEQERAGLQR DMLEGQDSKL PSSVRNTLLE 60
LFGQIEREFE NLYIENLELR REIDTLNERL AAEGQTIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCAATAG AAAGTGGAAG TTGTGCATCT GCTCGCCAAG CAAAGCAGAA ACGCAAATCG 60
CACAGTCTTT CAATCCGAAG AACCAACAGT TCTGAGCAAG AACGGGCAGG ACTGCAGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	92.54	0.00e+00	932.00
IUUC-Apl-003647	Anas platyrhynchos	98.79	0.00e+00	976.00
IUUC-Aca-004759	Anolis carolinensis	96.17	0.00e+00	973.00
IUUC-Ame-011103	Astyanax mexicanus	56.75	1.00e-145	509.00
IUUC-Bta-012718	Bos taurus	92.54	0.00e+00	933.00
IUUC-Cel-018499	Caenorhabditis elegans	41.36	2.00e-95	342.00
IUUC-Cja-019492	Callithrix jacchus	93.35	0.00e+00	963.00
IUUC-Cfa-020199	Canis familiaris	91.94	0.00e+00	958.00
IUUC-Cpo-022500	Cavia porcellus	87.70	0.00e+00	913.00
IUUC-Csa-023567	Chlorocebus sabaeus	93.95	0.00e+00	971.00
IUUC-Cho-025071	Choloepus hoffmanni	67.14	0.00e+00	634.00
IUUC-Cin-025460	Ciona intestinalis	46.28	1.00e-105	376.00
IUUC-Csv-026042	Ciona savignyi	46.34	3.00e-107	381.00
IUUC-Dre-028214	Danio rerio	83.47	0.00e+00	871.00
IUUC-Dno-029826	Dasypus novemcinctus	95.18	0.00e+00	827.00
IUUC-Dor-030967	Dipodomys ordii	92.72	0.00e+00	866.00
IUUC-Dme-031936	Drosophila melanogaster	48.95	2.00e-117	415.00
IUUC-Ete-032452	Echinops telfairi	90.73	0.00e+00	934.00
IUUC-Eca-033278	Equus caballus	91.94	0.00e+00	959.00
IUUC-Eeu-034592	Erinaceus europaeus	80.04	0.00e+00	799.00
IUUC-Fca-036431	Felis catus	92.56	0.00e+00	961.00
IUUC-Fal-037149	Ficedula albicollis	98.39	0.00e+00	971.00
IUUC-Gmo-038476	Gadus morhua	80.04	0.00e+00	778.00
IUUC-Gga-041099	Gallus gallus	99.80	0.00e+00	985.00
IUUC-Gac-042374	Gasterosteus aculeatus	85.60	0.00e+00	837.00
IUUC-Ggo-044683	Gorilla gorilla	86.09	0.00e+00	877.00
IUUC-Hsa-046658	Homo sapiens	93.55	0.00e+00	966.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	95.16	0.00e+00	909.00
IUUC-Lch-050571	Latimeria chalumnae	85.96	0.00e+00	898.00
IUUC-Loc-052652	Lepisosteus oculatus	83.40	0.00e+00	876.00
IUUC-Laf-053712	Loxodonta africana	92.79	0.00e+00	961.00
IUUC-Mcc-055521	Macaca mulatta	93.95	0.00e+00	971.00
IUUC-Meu-056324	Macropus eugenii	90.32	0.00e+00	893.00
IUUC-Mmr-061176	Microcebus murinus	93.55	0.00e+00	964.00
IUUC-Mdo-061888	Monodelphis domestica	94.96	0.00e+00	929.00
IUUC-Mmu-063977	Mus musculus	93.95	0.00e+00	976.00
IUUC-Mpu-066220	Mustela putorius furo	79.68	7.00e-173	599.00
IUUC-Mlu-068155	Myotis lucifugus	92.74	0.00e+00	964.00
IUUC-Nle-069964	Nomascus leucogenys	93.75	0.00e+00	968.00
IUUC-Opr-070925	Ochotona princeps	92.03	5.00e-146	510.00
IUUC-Ont-071317	Oreochromis niloticus	87.10	0.00e+00	862.00
IUUC-Oan-072952	Ornithorhynchus anatinus	95.77	0.00e+00	958.00
IUUC-Ocu-073913	Oryctolagus cuniculus	94.35	0.00e+00	979.00
IUUC-Ola-087024	Oryzias latipes	85.11	0.00e+00	892.00
IUUC-Oga-087945	Otolemur garnettii	93.15	0.00e+00	973.00
IUUC-Oar-089854	Ovis aries	92.74	0.00e+00	929.00
IUUC-Ptr-091486	Pan troglodytes	93.75	0.00e+00	967.00
IUUC-Pan-091738	Papio anubis	93.95	0.00e+00	971.00
IUUC-Psi-093953	Pelodiscus sinensis	97.18	0.00e+00	969.00
IUUC-Pma-094560	Petromyzon marinus	75.64	0.00e+00	783.00
IUUC-Pfo-097222	Poecilia formosa	82.86	0.00e+00	829.00
IUUC-Pab-098778	Pongo abelii	89.31	0.00e+00	909.00
IUUC-Pca-100852	Procavia capensis	89.92	0.00e+00	913.00
IUUC-Pva-103130	Pteropus vampyrus	91.25	1.00e-129	455.00
IUUC-Rno-105848	Rattus norvegicus	85.28	0.00e+00	862.00
IUUC-Sha-106750	Sarcophilus harrisii	95.36	0.00e+00	957.00
IUUC-Sar-113749	Sorex araneus	84.27	0.00e+00	854.00
IUUC-Ssc-115691	Sus scrofa	91.13	0.00e+00	910.00
IUUC-Tgu-117365	Taeniopygia guttata	97.78	0.00e+00	926.00
IUUC-Tru-117595	Takifugu rubripes	85.28	0.00e+00	847.00
IUUC-Tsy-118973	Tarsius syrichta	72.25	5.00e-147	513.00
IUUC-Tni-120545	Tetraodon nigroviridis	84.14	0.00e+00	875.00
IUUC-Tbe-127976	Tupaia belangeri	70.16	0.00e+00	672.00
IUUC-Ttr-128472	Tursiops truncatus	90.12	0.00e+00	925.00
IUUC-Xtr-132621	Xenopus tropicalis	92.54	0.00e+00	918.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence