iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-091773

Ensembl Protein ID

ENSPANP00000014038.1

UniProt Accession

A0A096NM29; A0A096NM29_PAPAN

Genbank Protein ID

ENSPANP00000014038

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01007304

Gene Name

USP50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000017629.1	ENSPANT00000025397.1	ENSPANP00000014038.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.60e-89	299.8	44	362

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           tGl+NlgNtCYmN++LQcL +i++l e++l+ k+  +l     +++  e++++++ l++ +w +++  vsp+ + +al+++ + f++  
   Q: 44   TGLRNLGNTCYMNAILQCLCSISPLVEYFLSgKYITAL-----QNDCSEVATAFAYLMTDMWLGDSDCVSPEIFRSALGNLYPAFTKKT 127
           7******************************3333333.....35678***************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           qqDaqEfl ++l++l+e+lkk    ++ + ++ + +   +   +k  + ++s+i++lF+gql  +i+cl+c++ + ++e f+ lslp+p
   Q: 128  QQDAQEFLIYVLNELHEALKK---YHYPRRRSHE-KGPAQRCCRKWITTETSVITQLFEGQLNYSIVCLKCEKCTYKNEVFTVLSLPIP 212
           *******************44...3333333333.345555678999999*************************************** PP
   S: 178  gkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfc 265
           ++ e+   slqdcL+ f+++++l+ +n+++c+ c+ kqe+  + +++k P+++i+hLkRf  + ++  ++k+ + +++pl+ Ldl+p+ 
   Q: 213  SEYEC---SLQDCLQCFFQQDTLTWNNQIHCSFCETKQETAVRAGISKAPKIIIFHLKRF--DIQRTTKRKLRTDIHYPLTnLDLTPYI 296
           *****...****************************************************..55667999******************* PP
   S: 266  tspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           +   +k   + kY+L+avv+H G l++GHY+a++kn+  + W+ fdD++V+e++ ++v++   +taY+lfY 
   Q: 297  CPIFRK---YPKYNLCAVVNHFGDLDGGHYTAFCKNSFTQaWYSFDDTRVSEIPDTSVQN---ATAYLLFYS 362
           **6655...8**************************76668*******************...********6 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MSSQRSLPAD DFGIYYVLAE CTDYYDTLPV KEADGSQPCS QGVTGLRNLG NTCYMNAILQ 60
CLCSISPLVE YFLSGKYITA LQNDCSEVAT AFAYLMTDMW LGDSDCVSPE IFRSALGNLY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTTCTC AGCGATCTCT CCCTGCAGAT GACTTCGGTA TCTACTATGT CCTGTGAGCC 60
TTGATCTACT ACAGCTTTCT AGATAAGCCC AGCTCAGAGG AGTCAGGGGA TACATGCTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002089	Ailuropoda melanoleuca	87.63	0.00e+00	674.00
IUUC-Aca-005256	Anolis carolinensis	48.07	1.00e-97	349.00
IUUC-Bta-012753	Bos taurus	81.99	0.00e+00	627.00
IUUC-Cfa-020054	Canis familiaris	86.23	2.00e-174	604.00
IUUC-Cpo-021375	Cavia porcellus	75.20	8.00e-166	576.00
IUUC-Csa-023902	Chlorocebus sabaeus	97.73	8.00e-128	449.00
IUUC-Cho-024755	Choloepus hoffmanni	75.29	5.00e-145	506.00
IUUC-Dor-030311	Dipodomys ordii	87.91	2.00e-94	338.00
IUUC-Ete-032570	Echinops telfairi	65.31	2.00e-106	378.00
IUUC-Eca-034343	Equus caballus	87.10	0.00e+00	667.00
IUUC-Eeu-034510	Erinaceus europaeus	84.42	2.00e-162	564.00
IUUC-Fca-035920	Felis catus	86.29	0.00e+00	673.00
IUUC-Fal-036903	Ficedula albicollis	56.21	6.00e-108	383.00
IUUC-Gac-042261	Gasterosteus aculeatus	43.49	2.00e-72	265.00
IUUC-Ggo-045650	Gorilla gorilla	85.81	6.00e-71	260.00
IUUC-Hsa-046665	Homo sapiens	88.34	2.00e-178	618.00
IUUC-Itr-048167	Ictidomys tridecemlineatus	90.59	0.00e+00	708.00
IUUC-Lch-049925	Latimeria chalumnae	54.41	2.00e-102	365.00
IUUC-Loc-051880	Lepisosteus oculatus	47.67	4.00e-80	292.00
IUUC-Laf-054494	Loxodonta africana	88.08	0.00e+00	682.00
IUUC-Mcc-055507	Macaca mulatta	98.86	0.00e+00	726.00
IUUC-Meu-055906	Macropus eugenii	76.58	1.00e-154	538.00
IUUC-Mmr-061564	Microcebus murinus	65.00	2.00e-112	398.00
IUUC-Mdo-061800	Monodelphis domestica	78.08	1.00e-172	598.00
IUUC-Mmu-063618	Mus musculus	82.53	0.00e+00	630.00
IUUC-Mpu-066699	Mustela putorius furo	88.17	0.00e+00	682.00
IUUC-Mlu-067672	Myotis lucifugus	84.95	0.00e+00	655.00
IUUC-Opr-070949	Ochotona princeps	84.44	8.00e-157	545.00
IUUC-Ont-072200	Oreochromis niloticus	45.12	3.00e-69	255.00
IUUC-Oan-073725	Ornithorhynchus anatinus	66.48	6.00e-141	493.00
IUUC-Ocu-074021	Oryctolagus cuniculus	90.59	0.00e+00	705.00
IUUC-Oga-088258	Otolemur garnettii	88.29	3.00e-167	580.00
IUUC-Oar-089881	Ovis aries	84.68	0.00e+00	654.00
IUUC-Ptr-090988	Pan troglodytes	89.55	1.00e-174	605.00
IUUC-Psi-093243	Pelodiscus sinensis	73.19	3.00e-138	484.00
IUUC-Pab-097713	Pongo abelii	90.65	0.00e+00	662.00
IUUC-Pca-100226	Procavia capensis	66.76	4.00e-130	457.00
IUUC-Pva-103172	Pteropus vampyrus	87.06	9.00e-177	612.00
IUUC-Rno-105950	Rattus norvegicus	84.41	0.00e+00	642.00
IUUC-Sha-107026	Sarcophilus harrisii	78.25	4.00e-169	587.00
IUUC-Ssc-116383	Sus scrofa	88.17	0.00e+00	683.00
IUUC-Tgu-116511	Taeniopygia guttata	56.38	2.00e-101	361.00
IUUC-Tbe-127808	Tupaia belangeri	83.94	6.00e-62	230.00
IUUC-Ttr-129046	Tursiops truncatus	82.94	4.00e-165	573.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence