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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-105381
UUCD1 version UUC-RaN-00241
Ensembl Protein ID ENSRNOP00000074638.1
UniProt Accession A0A0G2K8K2; A0A0G2K8K2_RAT
Genbank Protein ID ENSRNOP00000074638
Protein Name E3 ubiquitin-protein ligase CBL-B
Genbank Nucleotide ID AABR07034073
Gene Name Cblb
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000001982.7 ENSRNOT00000077220.1 ENSRNOP00000074638.1
ENSRNOG00000001982.7 ENSRNOT00000002719.4 ENSRNOP00000002719.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACRAID2
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 1.10e-07 32.6 373 412
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl +w    ++s ++  CP Cr
   Q: 373  CKICAENDKD-VKIEPCGHLMCTSCLTAW----QESDGQ-GCPFCR 412
           99********.******************....555555.5****8 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MANSMNGRNP GGRGGNPRKG RILGIIDAIQ DAVGPPKQAA ADRRTVEKTW KLMDKVVRLC 60
QNPKLQLKNS PPYILDILPD TYQHLRLILS KYDDNQKLAQ LSENEYFKIY IDSLMKKSKR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105381|E3,RING|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCTTAGCTCC GCCCCACGCC TTGGTCTCCG GGGATGGCTC AGGGGTGGGG TGGCCAGTGA 60
GTGGTCTCCT CCTCCGGCGG GCGCTGCGGC GGCCTCCCGA GAGTGGCGCG GGACTGCCGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105381|E3,RING|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3
SMART

SM00184--RING
SM00165--UBA
Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001412 Ailuropoda melanoleuca 94.40 0.00e+00 1638.00
IUUC-Apl-004148 Anas platyrhynchos 84.61 0.00e+00 1472.00
IUUC-Aca-005204 Anolis carolinensis 82.07 0.00e+00 1421.00
IUUC-Ame-011919 Astyanax mexicanus 63.96 0.00e+00 1041.00
IUUC-Bta-013044 Bos taurus 94.71 0.00e+00 1641.00
IUUC-Cel-018674 Caenorhabditis elegans 56.92 2.00e-133 469.00
IUUC-Cja-018813 Callithrix jacchus 87.53 0.00e+00 1516.00
IUUC-Cfa-021054 Canis familiaris 94.20 0.00e+00 1679.00
IUUC-Cpo-022514 Cavia porcellus 90.33 0.00e+00 1632.00
IUUC-Csa-024110 Chlorocebus sabaeus 94.81 0.00e+00 1662.00
IUUC-Cho-024886 Choloepus hoffmanni 78.00 0.00e+00 1110.00
IUUC-Dre-027480 Danio rerio 63.74 0.00e+00 1029.00
IUUC-Dno-028923 Dasypus novemcinctus 94.30 0.00e+00 1633.00
IUUC-Dor-031040 Dipodomys ordii 89.34 0.00e+00 805.00
IUUC-Ete-032406 Echinops telfairi 89.21 0.00e+00 1489.00
IUUC-Eca-033849 Equus caballus 93.59 0.00e+00 1658.00
IUUC-Fca-036224 Felis catus 94.82 0.00e+00 1644.00
IUUC-Fal-036860 Ficedula albicollis 97.09 0.00e+00 1009.00
IUUC-Gga-040159 Gallus gallus 81.59 0.00e+00 1427.00
IUUC-Gac-042312 Gasterosteus aculeatus 60.41 0.00e+00 976.00
IUUC-Ggo-045175 Gorilla gorilla 87.92 0.00e+00 1526.00
IUUC-Hsa-046306 Homo sapiens 94.71 0.00e+00 1660.00
IUUC-Lch-049931 Latimeria chalumnae 60.56 0.00e+00 838.00
IUUC-Loc-052524 Lepisosteus oculatus 68.79 0.00e+00 1091.00
IUUC-Laf-053635 Loxodonta africana 90.65 0.00e+00 1584.00
IUUC-Mcc-055536 Macaca mulatta 94.71 0.00e+00 1660.00
IUUC-Meu-056045 Macropus eugenii 79.29 0.00e+00 1288.00
IUUC-Mga-060177 Meleagris gallopavo 90.94 0.00e+00 1117.00
IUUC-Mmr-061088 Microcebus murinus 95.42 0.00e+00 1679.00
IUUC-Mdo-062020 Monodelphis domestica 89.81 0.00e+00 1558.00
IUUC-Mmu-063114 Mus musculus 93.89 0.00e+00 1649.00
IUUC-Mpu-066632 Mustela putorius furo 95.02 0.00e+00 1680.00
IUUC-Mlu-067145 Myotis lucifugus 94.61 0.00e+00 1669.00
IUUC-Ont-072323 Oreochromis niloticus 72.77 0.00e+00 893.00
IUUC-Oan-073165 Ornithorhynchus anatinus 87.82 0.00e+00 1579.00
IUUC-Ocu-074723 Oryctolagus cuniculus 94.71 0.00e+00 1675.00
IUUC-Oga-088021 Otolemur garnettii 93.70 0.00e+00 1638.00
IUUC-Oar-089809 Ovis aries 94.51 0.00e+00 1641.00
IUUC-Ptr-090834 Pan troglodytes 94.61 0.00e+00 1657.00
IUUC-Pan-092225 Papio anubis 94.71 0.00e+00 1662.00
IUUC-Psi-093317 Pelodiscus sinensis 85.11 0.00e+00 1519.00
IUUC-Pma-094249 Petromyzon marinus 77.61 5.00e-127 446.00
IUUC-Pab-097595 Pongo abelii 94.71 0.00e+00 1659.00
IUUC-Pca-100844 Procavia capensis 78.64 0.00e+00 1303.00
IUUC-Pva-103216 Pteropus vampyrus 88.30 0.00e+00 1559.00
IUUC-Sha-107574 Sarcophilus harrisii 89.95 0.00e+00 1558.00
IUUC-Sar-113500 Sorex araneus 82.46 0.00e+00 1344.00
IUUC-Ssc-115856 Sus scrofa 93.54 0.00e+00 1416.00
IUUC-Tgu-116866 Taeniopygia guttata 85.20 0.00e+00 1472.00
IUUC-Tru-118579 Takifugu rubripes 86.15 0.00e+00 887.00
IUUC-Tsy-119167 Tarsius syrichta 82.74 0.00e+00 1384.00
IUUC-Tni-120788 Tetraodon nigroviridis 85.03 0.00e+00 898.00
IUUC-Tbe-127830 Tupaia belangeri 91.64 0.00e+00 1147.00
IUUC-Ttr-128631 Tursiops truncatus 94.91 0.00e+00 1675.00
IUUC-Vpa-130713 Vicugna pacos 93.60 0.00e+00 1441.00
Created Date 25-Jun-2017

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