iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053742

UUCD1 version

UUC-LoA-00637

Ensembl Protein ID

ENSLAFP00000015549.3

UniProt Accession

G3TL12; G3TL12_LOXAF

Protein Name

Uncharacterized protein

Gene Name

CDC20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000018549.3	ENSLAFT00000018549.3	ENSLAFP00000015549.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	3.30e-147	490.0	172	478
E3 adaptor/Cullin RING/DCX/DWD	1.30e-27	95.1	307	336

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldape+r+d+ylnL+dWss nvlavaL++svylwsa++gd+ +l ++ +++++v+sv+wi+eg++lavGt+++ev+++Dv+++k+
   Q: 172  PDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMeQPGEYVSSVAWIKEGNYLAVGTSSAEVQLWDVQQQKR 260
           689************************************************899*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....Plk 173
           +r++t+hsarvg+L Wn+++lssGsr+g+i+h+dvrv+e++++tl++h+qevCGl+w+ d+++LasGGnDn v+vw ++  e    Pl+
   Q: 261  LRNMTSHSARVGSLCWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEggwvPLQ 349
           ********************************************************************************9999***** PP
   S: 174  kfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvae 262
           +f++h++avka+aw+Pwq+s+La+GGGt+Dr+i++wn+++ga+l+++d++sqvcs+lws+++kel+s+hGfa+n++++wkyp+++kvae
   Q: 350  TFTQHQGAVKAVAWCPWQSSVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAE 438
           ***************************************************************************************** PP
   S: 263  lkgheaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           lkgh+aRvlsl++spdg+++++aa+Detlr+w++f+ ++a
   Q: 439  LKGHTARVLSLTMSPDGATVASAAADETLRLWRCFELDPA 478
           ***********************************99876 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+ +v++l++ +d ++l+sG++D+ + vW
   Q: 307  GHSQEVCGLRWaPDgRHLASGGNDNLVNVW 336
           8***********999*************** PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAHFVFESDL HSLLQLDAPI PNAPPARWQR KAKEAAGPAP SPMRAANRSH SAGRTPGRTP 60
GKSSSKAQTT PSKAGGDRYI PHRSASQMEV ASFLLSKENQ PENSQTPTKK EHQKAWALNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCATT TTGTGTTCGA GAGTGACCTG CACTCGCTGC TCCAGCTGGA CGCACCCATC 60
CCCAATGCAC CCCCCGCACG CTGGCAGCGC AAAGCTAAGG AAGCAGCGGG GCCGGCCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0007064--P:mitotic sister chromatid cohesion
GO:0090307--P:mitotic spindle assembly
GO:0090129--P:positive regulation of synapse maturation
GO:0031915--P:positive regulation of synaptic plasticity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

KEGG

lav:100667610

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000638	Aegilops tauschii	45.88	2.00e-109	389.00
IUUC-Aml-001545	Ailuropoda melanoleuca	97.60	0.00e+00	946.00
IUUC-Atr-003103	Amborella trichopoda	45.97	1.00e-107	383.00
IUUC-Apl-003255	Anas platyrhynchos	80.45	0.00e+00	751.00
IUUC-Aca-004920	Anolis carolinensis	75.44	0.00e+00	774.00
IUUC-Aly-006012	Arabidopsis lyrata	49.02	3.00e-109	388.00
IUUC-Ath-006795	Arabidopsis thaliana	46.48	4.00e-107	381.00
IUUC-Ago-007784	Ashbya gossypii	47.63	1.00e-84	306.00
IUUC-Acl-008269	Aspergillus clavatus	48.18	6.00e-96	344.00
IUUC-Afl-008432	Aspergillus flavus	47.51	1.00e-96	347.00
IUUC-Afu-008829	Aspergillus fumigatus	47.21	1.00e-96	347.00
IUUC-Ani-009471	Aspergillus nidulans	47.51	3.00e-98	352.00
IUUC-Ang-009711	Aspergillus niger	48.63	9.00e-97	347.00
IUUC-Aor-010118	Aspergillus oryzae	47.51	1.00e-96	347.00
IUUC-Ate-010479	Aspergillus terreus	50.16	4.00e-91	328.00
IUUC-Ame-010850	Astyanax mexicanus	60.70	2.00e-91	328.00
IUUC-Bgr-012059	Blumeria graminis	48.12	1.00e-94	340.00
IUUC-Bta-012625	Bos taurus	97.19	0.00e+00	947.00
IUUC-Bci-013607	Botrytis cinerea	47.95	2.00e-98	352.00
IUUC-Bdi-014344	Brachypodium distachyon	47.04	1.00e-108	386.00
IUUC-Bol-015368	Brassica oleracea	45.65	1.00e-105	377.00
IUUC-Bra-016738	Brassica rapa	46.12	3.00e-105	375.00
IUUC-Cel-018472	Caenorhabditis elegans	48.57	1.00e-88	320.00
IUUC-Cja-019132	Callithrix jacchus	96.99	0.00e+00	947.00
IUUC-Cfa-020780	Canis familiaris	97.39	0.00e+00	945.00
IUUC-Cpo-022223	Cavia porcellus	96.59	0.00e+00	894.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	49.30	4.00e-115	408.00
IUUC-Csa-023666	Chlorocebus sabaeus	97.80	0.00e+00	948.00
IUUC-Cho-024920	Choloepus hoffmanni	97.87	8.00e-163	566.00
IUUC-Cin-025675	Ciona intestinalis	50.60	1.00e-133	469.00
IUUC-Csv-026019	Ciona savignyi	50.38	1.00e-129	456.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	47.11	5.00e-96	345.00
IUUC-Cne-026933	Cryptococcus neoformans	46.32	5.00e-89	322.00
IUUC-Cme-027234	Cyanidioschyzon merolae	52.19	4.00e-105	375.00
IUUC-Dre-028026	Danio rerio	59.56	1.00e-180	625.00
IUUC-Dno-028865	Dasypus novemcinctus	97.40	0.00e+00	941.00
IUUC-Dor-030958	Dipodomys ordii	95.79	0.00e+00	936.00
IUUC-Dse-031391	Dothistroma septosporum	48.50	6.00e-96	344.00
IUUC-Dme-031905	Drosophila melanogaster	49.25	2.00e-143	502.00
IUUC-Ete-032387	Echinops telfairi	92.59	0.00e+00	911.00
IUUC-Eca-033522	Equus caballus	87.37	0.00e+00	848.00
IUUC-Eeu-035059	Erinaceus europaeus	84.00	0.00e+00	787.00
IUUC-Fca-036346	Felis catus	97.73	0.00e+00	867.00
IUUC-Fal-037558	Ficedula albicollis	79.76	0.00e+00	794.00
IUUC-Fox-037850	Fusarium oxysporum	45.05	2.00e-97	350.00
IUUC-Fso-038375	Fusarium solani	45.08	3.00e-98	352.00
IUUC-Gmo-039284	Gadus morhua	61.51	7.00e-180	623.00
IUUC-Ggr-039864	Gaeumannomyces graminis	47.97	1.00e-97	350.00
IUUC-Gga-040790	Gallus gallus	80.35	0.00e+00	817.00
IUUC-Gac-041431	Gasterosteus aculeatus	60.83	2.00e-177	614.00
IUUC-Gma-043489	Glycine max	46.84	5.00e-106	377.00
IUUC-Ggo-045052	Gorilla gorilla	97.80	0.00e+00	949.00
IUUC-Hsa-046305	Homo sapiens	97.80	0.00e+00	949.00
IUUC-Hvu-047476	Hordeum vulgare	45.12	7.00e-109	387.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	96.99	0.00e+00	896.00
IUUC-Kpa-049239	Komagataella pastoris	53.02	6.00e-96	344.00
IUUC-Lch-050174	Latimeria chalumnae	61.20	2.00e-173	601.00
IUUC-Lpe-050954	Leersia perrieri	46.90	3.00e-100	358.00
IUUC-Loc-052638	Lepisosteus oculatus	63.12	0.00e+00	635.00
IUUC-Lma-052998	Leptosphaeria maculans	43.05	3.00e-99	355.00
IUUC-Mcc-054948	Macaca mulatta	97.80	0.00e+00	948.00
IUUC-Meu-056013	Macropus eugenii	86.57	1.00e-142	499.00
IUUC-Mor-057277	Magnaporthe oryzae	41.46	5.00e-96	345.00
IUUC-Mpo-057624	Magnaporthe poae	51.14	5.00e-96	345.00
IUUC-Mtr-057725	Medicago truncatula	45.60	9.00e-99	353.00
IUUC-Mla-059048	Melampsora laricipopulina	49.07	5.00e-83	301.00
IUUC-Mga-060102	Meleagris gallopavo	80.59	0.00e+00	819.00
IUUC-Mvi-060465	Microbotryum violaceum	47.04	7.00e-92	331.00
IUUC-Mmr-061615	Microcebus murinus	97.91	0.00e+00	943.00
IUUC-Mdo-061982	Monodelphis domestica	89.12	0.00e+00	776.00
IUUC-Mmu-063864	Mus musculus	93.79	0.00e+00	925.00
IUUC-Mac-064861	Musa acuminata	47.46	2.00e-109	389.00
IUUC-Mpu-066502	Mustela putorius furo	97.19	0.00e+00	939.00
IUUC-Mlu-067277	Myotis lucifugus	89.82	0.00e+00	884.00
IUUC-Nfi-068536	Neosartorya fischeri	47.21	1.00e-96	346.00
IUUC-Ncr-068951	Neurospora crassa	45.60	7.00e-95	341.00
IUUC-Nle-070149	Nomascus leucogenys	97.80	0.00e+00	944.00
IUUC-Opr-070778	Ochotona princeps	95.26	0.00e+00	684.00
IUUC-Ont-071660	Oreochromis niloticus	60.16	7.00e-176	610.00
IUUC-Oan-073677	Ornithorhynchus anatinus	77.29	0.00e+00	707.00
IUUC-Ocu-073797	Oryctolagus cuniculus	96.98	0.00e+00	940.00
IUUC-Oba-075514	Oryza barthii	47.62	1.00e-100	360.00
IUUC-Obr-076018	Oryza brachyantha	45.80	6.00e-108	384.00
IUUC-Ogl-077254	Oryza glaberrima	47.38	1.00e-100	360.00
IUUC-Ogu-078521	Oryza glumaepatula	47.54	4.00e-107	382.00
IUUC-Oin-079145	Oryza indica	47.38	1.00e-107	383.00
IUUC-Olo-080449	Oryza longistaminata	47.38	1.00e-100	360.00
IUUC-Ome-081186	Oryza meridionalis	47.14	1.00e-107	384.00
IUUC-Oni-082243	Oryza nivara	47.38	1.00e-100	360.00
IUUC-Opu-084007	Oryza punctata	47.38	8.00e-100	357.00
IUUC-Oru-084562	Oryza rufipogon	47.54	7.00e-107	381.00
IUUC-Osa-086094	Oryza sativa	47.38	2.00e-100	359.00
IUUC-Ola-086907	Oryzias latipes	60.43	5.00e-164	570.00
IUUC-Olu-087647	Ostreococcus lucimarinus	48.08	8.00e-119	420.00
IUUC-Oga-088184	Otolemur garnettii	96.40	0.00e+00	932.00
IUUC-Oar-090023	Ovis aries	91.88	0.00e+00	844.00
IUUC-Ptr-090935	Pan troglodytes	97.04	0.00e+00	885.00
IUUC-Pan-091845	Papio anubis	97.80	0.00e+00	948.00
IUUC-Psi-093188	Pelodiscus sinensis	80.54	0.00e+00	840.00
IUUC-Pma-094187	Petromyzon marinus	53.96	1.00e-146	513.00
IUUC-Pno-094809	Phaeosphaeria nodorum	42.04	2.00e-100	359.00
IUUC-Ppa-095457	Physcomitrella patens	47.92	2.00e-109	389.00
IUUC-Pfo-097429	Poecilia formosa	57.97	1.00e-158	552.00
IUUC-Pab-098603	Pongo abelii	98.00	0.00e+00	949.00
IUUC-Pop-099654	Populus trichocarpa	45.91	2.00e-101	362.00
IUUC-Pca-101062	Procavia capensis	98.00	0.00e+00	938.00
IUUC-Ppe-101865	Prunus persica	46.30	1.00e-95	343.00
IUUC-Pva-102925	Pteropus vampyrus	95.79	0.00e+00	965.00
IUUC-Pgr-103466	Puccinia graminis	49.06	7.00e-85	308.00
IUUC-Ptt-103888	Puccinia triticina	46.24	2.00e-77	283.00
IUUC-Pte-104142	Pyrenophora teres	49.55	1.00e-97	350.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	41.81	2.00e-97	350.00
IUUC-Rno-106005	Rattus norvegicus	93.99	0.00e+00	924.00
IUUC-Sce-106240	Saccharomyces cerevisiae	43.27	4.00e-82	298.00
IUUC-Sha-107472	Sarcophilus harrisii	89.80	0.00e+00	892.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	41.94	2.00e-93	336.00
IUUC-Spo-108075	Schizosaccharomyces pombe	44.47	4.00e-96	344.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	51.46	4.00e-97	348.00
IUUC-Smo-108922	Selaginella moellendorffii	49.25	2.00e-123	435.00
IUUC-Sit-110732	Setaria italica	46.48	2.00e-108	385.00
IUUC-Sly-111202	Solanum lycopersicum	44.65	4.00e-105	374.00
IUUC-Stu-112024	Solanum tuberosum	43.23	2.00e-105	375.00
IUUC-Sar-113092	Sorex araneus	91.78	0.00e+00	884.00
IUUC-Sbi-114558	Sorghum bicolor	45.49	2.00e-108	385.00
IUUC-Sre-115222	Sporisorium reilianum	49.10	3.00e-92	332.00
IUUC-Ssc-115710	Sus scrofa	98.20	0.00e+00	952.00
IUUC-Tgu-117100	Taeniopygia guttata	79.17	0.00e+00	796.00
IUUC-Tru-118184	Takifugu rubripes	57.34	1.00e-138	486.00
IUUC-Tsy-118892	Tarsius syrichta	96.81	6.00e-162	562.00
IUUC-Tni-120474	Tetraodon nigroviridis	58.81	3.00e-167	581.00
IUUC-Tca-120949	Theobroma cacao	46.38	5.00e-106	377.00
IUUC-Tre-122211	Trichoderma reesei	40.49	2.00e-96	346.00
IUUC-Tvi-122531	Trichoderma virens	40.40	4.00e-96	345.00
IUUC-Tae-123017	Triticum aestivum	45.35	2.00e-109	389.00
IUUC-Tur-126193	Triticum urartu	45.35	4.00e-109	388.00
IUUC-Tme-127151	Tuber melanosporum	39.86	2.00e-94	340.00
IUUC-Tbe-127384	Tupaia belangeri	97.98	1.00e-175	608.00
IUUC-Ttr-128511	Tursiops truncatus	97.19	0.00e+00	942.00
IUUC-Uma-129555	Ustilago maydis	48.80	8.00e-92	331.00
IUUC-Vda-129993	Verticillium dahliae	40.17	3.00e-97	348.00
IUUC-Vvi-131245	Vitis vinifera	46.80	1.00e-93	336.00
IUUC-Xtr-131993	Xenopus tropicalis	73.29	0.00e+00	754.00
IUUC-Xma-133332	Xiphophorus maculatus	61.34	4.00e-175	607.00
IUUC-Yli-134584	Yarrowia lipolytica	50.16	9.00e-100	357.00
IUUC-Zma-135135	Zea mays	47.17	1.00e-106	380.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence