iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069793

Ensembl Protein ID

ENSNLEP00000017969.2

UniProt Accession

G1RXJ2; G1RXJ2_NOMLE

Genbank Protein ID

ENSNLEP00000017969

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01165887

Gene Name

AHI1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000014767.2	ENSNLET00000018863.2	ENSNLEP00000017969.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-19	69.1	651	681
UBD/SH3	2.60e-14	52.9	1054	1106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gH + +++l++  +d++++++s Dgt ++W 
   Q: 651  GHLNIIYDLSWskDDRYILTSSSDGTARIWK 681
           79999*******666***************7 PP

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v +lydy+a+ +deLt+++Gd+++v    + +e+W++g +  +g++G fP+n v+
   Q: 1054 TVVALYDYTANRSDELTIHRGDIIRVF--FKDNEDWWYG-SIGKGQEGYFPANHVA 1106
           689***********************9..8999******.799**********996 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MPTAESEAKV KTKVRFEELL KTHSDLVCEK KKLKKKLVKS EENISPDTIR SNPHYIKETT 60
SDDPDTIRSN LPHIKETTSD DVSAANTNNL KKSMRVTKNK LRNTQSANEN PNGDASVEED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGCGCAGA GTCGCGGCTT GCTCTCAGAA CACCGGTCGC TGGCGGGTTA GGTAGCTGCG 60
CGGCCGCCTC ACTTCGCGCT CGCGCCGCTA GGCTGGGGGA GTCGGTTTGC AGTGCTCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR023302--Pept_S9A_N
IPR001452--SH3_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50002--SH3
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00018--SH3_1
PF00400--WD40

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3
SM00320--WD40

Gene Ontology

GO:0005912--C:adherens junction
GO:0005911--C:cell-cell junction
GO:0005814--C:centriole
GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0005929--C:cilium
GO:0097730--C:non-motile cilium
GO:0034613--P:cellular protein localization
GO:0007417--P:central nervous system development
GO:0060271--P:cilium assembly
GO:0035844--P:cloaca development
GO:0001947--P:heart looping
GO:0030902--P:hindbrain development
GO:0070121--P:Kupffer's vesicle development
GO:0070986--P:left/right axis specification
GO:0001738--P:morphogenesis of a polarized epithelium
GO:0043066--P:negative regulation of apoptotic process
GO:0071599--P:otic vesicle development
GO:0035845--P:photoreceptor cell outer segment organization
GO:0030862--P:positive regulation of polarized epithelial cell differentiation
GO:0002092--P:positive regulation of receptor internalization
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0039023--P:pronephric duct morphogenesis
GO:0039008--P:pronephric nephron tubule morphogenesis
GO:0050795--P:regulation of behavior
GO:0010842--P:retina layer formation
GO:0065001--P:specification of axis polarity
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001943	Ailuropoda melanoleuca	82.95	0.00e+00	1644.00
IUUC-Apl-004057	Anas platyrhynchos	50.60	0.00e+00	1057.00
IUUC-Aca-004306	Anolis carolinensis	53.80	0.00e+00	931.00
IUUC-Ame-010981	Astyanax mexicanus	48.86	0.00e+00	836.00
IUUC-Bta-013129	Bos taurus	82.10	0.00e+00	1815.00
IUUC-Cja-018979	Callithrix jacchus	89.38	0.00e+00	1774.00
IUUC-Cfa-020121	Canis familiaris	82.34	0.00e+00	1862.00
IUUC-Cpo-022219	Cavia porcellus	80.00	0.00e+00	1338.00
IUUC-Csa-023991	Chlorocebus sabaeus	94.26	0.00e+00	2197.00
IUUC-Cho-024782	Choloepus hoffmanni	76.83	0.00e+00	952.00
IUUC-Cin-025149	Ciona intestinalis	39.51	2.00e-168	585.00
IUUC-Csv-026188	Ciona savignyi	39.06	9.00e-125	440.00
IUUC-Dre-028737	Danio rerio	49.83	0.00e+00	852.00
IUUC-Dno-029756	Dasypus novemcinctus	80.11	0.00e+00	1734.00
IUUC-Dor-030821	Dipodomys ordii	70.27	0.00e+00	1519.00
IUUC-Ete-032237	Echinops telfairi	73.47	0.00e+00	1575.00
IUUC-Eca-033491	Equus caballus	81.57	0.00e+00	1889.00
IUUC-Eeu-034812	Erinaceus europaeus	73.67	0.00e+00	949.00
IUUC-Fca-035868	Felis catus	81.95	0.00e+00	1812.00
IUUC-Fal-037571	Ficedula albicollis	62.54	0.00e+00	777.00
IUUC-Gmo-039358	Gadus morhua	50.06	0.00e+00	780.00
IUUC-Gga-040233	Gallus gallus	54.68	0.00e+00	976.00
IUUC-Gac-041744	Gasterosteus aculeatus	47.37	0.00e+00	798.00
IUUC-Ggo-044766	Gorilla gorilla	96.66	0.00e+00	2266.00
IUUC-Hsa-046660	Homo sapiens	96.49	0.00e+00	2261.00
IUUC-Itr-048282	Ictidomys tridecemlineatus	85.54	0.00e+00	1949.00
IUUC-Loc-052658	Lepisosteus oculatus	49.22	0.00e+00	926.00
IUUC-Laf-053564	Loxodonta africana	85.63	0.00e+00	1446.00
IUUC-Mcc-055480	Macaca mulatta	93.76	0.00e+00	2191.00
IUUC-Meu-056362	Macropus eugenii	54.39	0.00e+00	873.00
IUUC-Mga-060033	Meleagris gallopavo	51.85	0.00e+00	1086.00
IUUC-Mmr-061075	Microcebus murinus	83.84	0.00e+00	1946.00
IUUC-Mdo-062818	Monodelphis domestica	55.05	0.00e+00	1177.00
IUUC-Mmu-063987	Mus musculus	78.64	0.00e+00	1617.00
IUUC-Mpu-066242	Mustela putorius furo	78.71	0.00e+00	1760.00
IUUC-Mlu-067123	Myotis lucifugus	77.50	0.00e+00	1675.00
IUUC-Opr-071110	Ochotona princeps	74.78	0.00e+00	872.00
IUUC-Ont-072179	Oreochromis niloticus	48.43	0.00e+00	814.00
IUUC-Oan-073201	Ornithorhynchus anatinus	64.04	2.00e-135	474.00
IUUC-Ocu-074224	Oryctolagus cuniculus	83.84	0.00e+00	1984.00
IUUC-Ola-086818	Oryzias latipes	52.78	2.00e-72	264.00
IUUC-Oga-088338	Otolemur garnettii	85.87	0.00e+00	1813.00
IUUC-Oar-089247	Ovis aries	79.05	0.00e+00	1827.00
IUUC-Ptr-090830	Pan troglodytes	97.50	0.00e+00	2202.00
IUUC-Pan-092469	Papio anubis	95.07	0.00e+00	2237.00
IUUC-Psi-093183	Pelodiscus sinensis	51.03	0.00e+00	1049.00
IUUC-Pma-094415	Petromyzon marinus	47.40	2.00e-160	558.00
IUUC-Pfo-096577	Poecilia formosa	45.95	0.00e+00	794.00
IUUC-Pab-098236	Pongo abelii	96.24	0.00e+00	1914.00
IUUC-Pca-100560	Procavia capensis	66.47	0.00e+00	1438.00
IUUC-Pva-102565	Pteropus vampyrus	68.84	0.00e+00	1501.00
IUUC-Rno-104881	Rattus norvegicus	78.23	0.00e+00	1623.00
IUUC-Sha-106577	Sarcophilus harrisii	64.97	7.00e-162	563.00
IUUC-Sar-113265	Sorex araneus	70.31	0.00e+00	1503.00
IUUC-Ssc-116174	Sus scrofa	80.82	0.00e+00	1822.00
IUUC-Tgu-116618	Taeniopygia guttata	47.81	0.00e+00	878.00
IUUC-Tru-117761	Takifugu rubripes	42.63	0.00e+00	684.00
IUUC-Tsy-119557	Tarsius syrichta	80.00	0.00e+00	954.00
IUUC-Tni-119782	Tetraodon nigroviridis	50.00	0.00e+00	810.00
IUUC-Tbe-127529	Tupaia belangeri	73.22	9.00e-154	538.00
IUUC-Ttr-128444	Tursiops truncatus	77.53	0.00e+00	1782.00
IUUC-Vpa-130337	Vicugna pacos	72.77	0.00e+00	1597.00
IUUC-Xtr-132055	Xenopus tropicalis	56.62	0.00e+00	727.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence