iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091134

UUCD1 version

UUC-PaT-01000

Ensembl Protein ID

ENSPTRP00000003097.2

UniProt Accession

H2Q0X0; H2Q0X0_PANTR

Genbank Protein ID

JAA02187.1; JAA15235.1; JAA26632.1; JAA35885.1

Protein Name

Ubiquitin-conjugating enzyme E2T (Putative)

Genbank Nucleotide ID

AACZ03002440; GABF01006910; GABD01006468; GABE01008854

Gene Name

UBE2T

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000001850.2	ENSPTRT00000003362.2	ENSPTRP00000003097.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.20e-46	157.0	6	145

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.. 87
           Rlk+el+ l+++pp+gi++ ++++ ++++++++ilG ++tpYe+gvFkle+ +pe+YPf+PP+++flt+i+hPn++++G++Cl++lk  
   Q: 6    RLKRELHMLATEPPPGITCWQDKD-QMDDLQAQILGGANTPYEKGVFKLEVIIPERYPFEPPQIRFLTPIYHPNIDSAGRICLDVLKlp 93
           99**********************.7************************************************************998 PP
   S: 88   eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++ +W+p l++++vl+siq l++epnp++pl +++++++k n+ ++ k++r+
   Q: 94   PKGAWRPSLNIATVLTSIQLLMSEPNPDDPLMADISSEFKYNKPAFLKNARQ 145
           99********************************************999985 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MQRASRLKRE LHMLATEPPP GITCWQDKDQ MDDLQAQILG GANTPYEKGV FKLEVIIPER 60
YPFEPPQIRF LTPIYHPNID SAGRICLDVL KLPPKGAWRP SLNIATVLTS IQLLMSEPNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCGAGGTC GCGCAGGCGC TGGTGCCCCG TTGGTCCGCG CGTTGCTTCG TTGTGAGGGG 60
TGTCAGCTCA GGTAAGCAAG GAGAGTATTC CGGTTCCCCA TCTGAAAGAA GGTACACTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0006281--P:DNA repair
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination

KEGG

ptr:457628

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000366	Aegilops tauschii	55.63	2.00e-47	183.00
IUUC-Aml-001392	Ailuropoda melanoleuca	88.83	2.00e-103	367.00
IUUC-Atr-003069	Amborella trichopoda	47.64	4.00e-52	198.00
IUUC-Apl-003914	Anas platyrhynchos	80.13	1.00e-76	278.00
IUUC-Aca-004381	Anolis carolinensis	73.58	5.00e-83	300.00
IUUC-Aly-006059	Arabidopsis lyrata	53.16	2.00e-46	179.00
IUUC-Ath-007669	Arabidopsis thaliana	61.48	1.00e-43	170.00
IUUC-Ame-011372	Astyanax mexicanus	66.67	3.00e-71	260.00
IUUC-Bta-012479	Bos taurus	81.73	5.00e-92	329.00
IUUC-Bdi-014043	Brachypodium distachyon	48.08	4.00e-54	206.00
IUUC-Bol-016011	Brassica oleracea	50.93	2.00e-44	172.00
IUUC-Bra-017419	Brassica rapa	50.93	5.00e-44	171.00
IUUC-Cja-019773	Callithrix jacchus	93.94	4.00e-108	383.00
IUUC-Cfa-020043	Canis familiaris	89.34	3.00e-102	363.00
IUUC-Cpo-021481	Cavia porcellus	89.34	5.00e-103	366.00
IUUC-Csa-024083	Chlorocebus sabaeus	96.45	8.00e-114	402.00
IUUC-Cho-024386	Choloepus hoffmanni	89.07	6.00e-97	345.00
IUUC-Cin-025419	Ciona intestinalis	66.23	3.00e-63	233.00
IUUC-Csv-026224	Ciona savignyi	66.88	1.00e-63	236.00
IUUC-Cme-027179	Cyanidioschyzon merolae	50.32	4.00e-42	163.00
IUUC-Dre-028800	Danio rerio	77.07	2.00e-74	271.00
IUUC-Dno-029833	Dasypus novemcinctus	89.34	4.00e-105	373.00
IUUC-Ete-032625	Echinops telfairi	88.46	5.00e-76	275.00
IUUC-Eca-033821	Equus caballus	93.63	1.00e-86	311.00
IUUC-Eeu-034578	Erinaceus europaeus	87.59	9.00e-68	248.00
IUUC-Fca-036398	Felis catus	89.85	3.00e-103	366.00
IUUC-Fal-037564	Ficedula albicollis	71.21	1.00e-78	285.00
IUUC-Gmo-039142	Gadus morhua	81.17	2.00e-74	270.00
IUUC-Gga-041054	Gallus gallus	69.90	2.00e-76	278.00
IUUC-Gac-041370	Gasterosteus aculeatus	77.92	2.00e-73	267.00
IUUC-Ggo-045370	Gorilla gorilla	98.98	3.00e-115	406.00
IUUC-Hsa-046513	Homo sapiens	99.49	1.00e-115	408.00
IUUC-Hvu-047694	Hordeum vulgare	54.97	4.00e-49	189.00
IUUC-Itr-049076	Ictidomys tridecemlineatus	88.32	2.00e-103	367.00
IUUC-Lch-050484	Latimeria chalumnae	71.51	2.00e-70	257.00
IUUC-Loc-051967	Lepisosteus oculatus	75.16	1.00e-72	265.00
IUUC-Laf-053377	Loxodonta africana	90.36	4.00e-106	376.00
IUUC-Mcc-055453	Macaca mulatta	95.94	2.00e-113	400.00
IUUC-Meu-056745	Macropus eugenii	78.68	4.00e-91	326.00
IUUC-Mga-059729	Meleagris gallopavo	69.90	2.00e-76	278.00
IUUC-Mmr-060581	Microcebus murinus	93.91	1.00e-109	388.00
IUUC-Mdo-062434	Monodelphis domestica	80.20	6.00e-88	318.00
IUUC-Mmu-064379	Mus musculus	84.77	2.00e-96	344.00
IUUC-Mac-064647	Musa acuminata	56.25	3.00e-46	177.00
IUUC-Mpu-066713	Mustela putorius furo	89.85	4.00e-103	366.00
IUUC-Mlu-067525	Myotis lucifugus	89.61	4.00e-82	296.00
IUUC-Nle-069757	Nomascus leucogenys	97.97	2.00e-114	404.00
IUUC-Opr-070756	Ochotona princeps	85.28	1.00e-99	355.00
IUUC-Ont-071956	Oreochromis niloticus	70.97	7.00e-76	276.00
IUUC-Oan-072745	Ornithorhynchus anatinus	83.73	8.00e-83	298.00
IUUC-Ocu-074423	Oryctolagus cuniculus	88.83	4.00e-103	366.00
IUUC-Oba-075569	Oryza barthii	58.28	8.00e-50	191.00
IUUC-Obr-076131	Oryza brachyantha	57.62	1.00e-49	190.00
IUUC-Ogl-077132	Oryza glaberrima	58.28	8.00e-50	191.00
IUUC-Ogu-078880	Oryza glumaepatula	58.28	5.00e-50	192.00
IUUC-Oin-079748	Oryza indica	58.28	4.00e-50	192.00
IUUC-Olo-080501	Oryza longistaminata	58.94	1.00e-50	194.00
IUUC-Ome-081248	Oryza meridionalis	58.28	9.00e-50	191.00
IUUC-Oni-083033	Oryza nivara	58.28	4.00e-50	192.00
IUUC-Opu-083664	Oryza punctata	58.28	4.00e-50	192.00
IUUC-Oru-084580	Oryza rufipogon	58.28	4.00e-50	192.00
IUUC-Osa-085721	Oryza sativa	58.28	4.00e-50	192.00
IUUC-Ola-087559	Oryzias latipes	75.15	2.00e-73	268.00
IUUC-Oga-088420	Otolemur garnettii	92.93	1.00e-106	378.00
IUUC-Oar-090082	Ovis aries	79.40	2.00e-89	320.00
IUUC-Pan-091735	Papio anubis	96.45	8.00e-114	402.00
IUUC-Psi-094064	Pelodiscus sinensis	73.26	1.00e-80	291.00
IUUC-Pma-094609	Petromyzon marinus	71.52	3.00e-67	246.00
IUUC-Ppa-095553	Physcomitrella patens	58.94	4.00e-50	192.00
IUUC-Pfo-096710	Poecilia formosa	67.54	2.00e-72	264.00
IUUC-Pab-098126	Pongo abelii	99.49	1.00e-115	408.00
IUUC-Pop-099108	Populus trichocarpa	53.95	3.00e-47	182.00
IUUC-Pca-100338	Procavia capensis	87.82	1.00e-101	361.00
IUUC-Ppe-101239	Prunus persica	58.70	4.00e-45	175.00
IUUC-Pva-102756	Pteropus vampyrus	81.51	1.00e-67	248.00
IUUC-Rno-105211	Rattus norvegicus	80.20	5.00e-90	323.00
IUUC-Sha-106969	Sarcophilus harrisii	75.12	4.00e-82	296.00
IUUC-Smo-109052	Selaginella moellendorffii	56.77	3.00e-46	177.00
IUUC-Sit-110464	Setaria italica	57.82	6.00e-48	185.00
IUUC-Sly-110971	Solanum lycopersicum	60.14	2.00e-48	186.00
IUUC-Stu-112126	Solanum tuberosum	60.81	8.00e-49	187.00
IUUC-Sar-113633	Sorex araneus	81.41	1.00e-91	328.00
IUUC-Sbi-114875	Sorghum bicolor	57.62	2.00e-49	190.00
IUUC-Ssc-116375	Sus scrofa	82.74	6.00e-90	322.00
IUUC-Tgu-117292	Taeniopygia guttata	81.05	4.00e-74	269.00
IUUC-Tru-118157	Takifugu rubripes	66.67	8.00e-59	218.00
IUUC-Tsy-119260	Tarsius syrichta	91.37	2.00e-104	370.00
IUUC-Tni-120162	Tetraodon nigroviridis	70.83	6.00e-73	266.00
IUUC-Tca-121255	Theobroma cacao	55.90	1.00e-37	150.00
IUUC-Tae-123184	Triticum aestivum	55.63	2.00e-47	183.00
IUUC-Tbe-127296	Tupaia belangeri	91.37	2.00e-106	377.00
IUUC-Ttr-128443	Tursiops truncatus	83.42	3.00e-94	337.00
IUUC-Vpa-130689	Vicugna pacos	81.22	8.00e-92	328.00
IUUC-Vvi-130925	Vitis vinifera	53.33	1.00e-47	182.00
IUUC-Xma-133779	Xiphophorus maculatus	73.81	1.00e-73	268.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence