iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036005

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02091620

Gene Name

ATG16L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000011322.3	ENSFCAT00000011325.3	ENSFCAP00000010520.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-30	103.3	423	462
UBD/Beta-Prp	1.10e-62	211.9	333	622

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           gH+++v + +f  ++ ++vsGs+D t+k+WDlr+ v++k+
   Q: 423  GHSGKVLSAKFllDNARIVSGSHDRTLKLWDLRSKVCIKT 462
           8***********64489********************985 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           +++++h++ +++v+fsp+++llatg++d+++k+w+v+  k+    slsg +a++t+++f++ g++l+ +s+D + ++w ++++   htl
   Q: 333  CVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGDKCefKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTL 421
           7899************************************9999********************************************* PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
           +gh+ +vls +f  ++ ++vsGshdrt+++wdl+++ c++++++g +    c  + +++++++sG+ D+++r+Wd+++++++r+++   
   Q: 422  TGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREME--L 504
           ****************************************9999988....888888889*************************6..6 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
            ++v+ l+++++++el+s+s+d  +k+ dl+ + + +t+ +      +  ++v fsp++ +++ gs++gs+++W + sg++ k+l++++
   Q: 505  LGKVTALDLNPERTELLSCSRDDLLKIIDLRVNAVRQTFSAPGfkcgSDWTRVVFSPDGGYVAAGSAEGSLYVWSVLSGKVEKVLSKQH 593
           9******************************999999999988888877778************************************* PP
   S: 265  ssvisvavlsfgdnvlvlgsedskvniwk 293
            s+i   ++s++++++v++++ s++ +w+
   Q: 594  GSSINAVAWSPSGSHVVSVDKGSRAVLWS 622
           999999999*****************997 PP

Organism

Felis catus

Protein Sequence
(Fasta)

GGCRRPVKFS SCLSLKRKMK RDCRDRWQLS LSWILPDNKL LEKSDLHSVL AHKLQAEKHD 60
VPNRHEVWGF SPGHDGAWND SQLQEMAQLR IKHQEELTEL HKKRGELAQL VIDLNNQMQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGATGTA GGAGGAAAGT CGGAAGGAGA CCATCCTGGA GAGGGAACCC ATCATTAAAT 60
AGCTGTAGTC AGTAGCGCAT GCCTGAAGGG CTAGGAGCCC CGACTGAGAT GAGAGGTAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0000045--P:autophagosome assembly
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	25.61	8.00e-33	135.00
IUUC-Aml-002242	Ailuropoda melanoleuca	89.78	0.00e+00	1062.00
IUUC-Apl-003384	Anas platyrhynchos	85.37	0.00e+00	1033.00
IUUC-Aca-004962	Anolis carolinensis	86.46	0.00e+00	1028.00
IUUC-Aly-005435	Arabidopsis lyrata	34.32	7.00e-45	174.00
IUUC-Ath-006948	Arabidopsis thaliana	34.65	1.00e-45	177.00
IUUC-Ame-010915	Astyanax mexicanus	79.75	7.00e-153	533.00
IUUC-Bta-012388	Bos taurus	94.75	0.00e+00	1129.00
IUUC-Bdi-014231	Brachypodium distachyon	29.19	2.00e-36	146.00
IUUC-Bol-016174	Brassica oleracea	34.32	5.00e-45	175.00
IUUC-Bra-017165	Brassica rapa	34.32	1.00e-44	174.00
IUUC-Cel-018131	Caenorhabditis elegans	38.44	8.00e-58	218.00
IUUC-Cja-018898	Callithrix jacchus	81.91	0.00e+00	925.00
IUUC-Cfa-020484	Canis familiaris	94.59	0.00e+00	1118.00
IUUC-Cpo-022156	Cavia porcellus	90.19	0.00e+00	1060.00
IUUC-Csa-024019	Chlorocebus sabaeus	89.51	0.00e+00	1046.00
IUUC-Cho-024311	Choloepus hoffmanni	78.89	0.00e+00	918.00
IUUC-Cin-025260	Ciona intestinalis	36.27	8.00e-97	347.00
IUUC-Csv-025836	Ciona savignyi	45.89	6.00e-48	183.00
IUUC-Dre-027702	Danio rerio	74.49	0.00e+00	854.00
IUUC-Dno-029728	Dasypus novemcinctus	93.58	0.00e+00	1140.00
IUUC-Dor-030587	Dipodomys ordii	91.81	2.00e-111	395.00
IUUC-Dme-031595	Drosophila melanogaster	39.67	8.00e-106	377.00
IUUC-Ete-032969	Echinops telfairi	74.71	0.00e+00	771.00
IUUC-Eca-034214	Equus caballus	94.29	0.00e+00	951.00
IUUC-Eeu-034537	Erinaceus europaeus	87.20	0.00e+00	895.00
IUUC-Fal-037593	Ficedula albicollis	87.74	0.00e+00	1029.00
IUUC-Gmo-039042	Gadus morhua	62.07	0.00e+00	639.00
IUUC-Gga-040986	Gallus gallus	88.25	0.00e+00	1049.00
IUUC-Gac-041351	Gasterosteus aculeatus	72.13	0.00e+00	871.00
IUUC-Gma-043452	Glycine max	33.99	8.00e-46	177.00
IUUC-Ggo-045427	Gorilla gorilla	93.41	0.00e+00	1097.00
IUUC-Hsa-046632	Homo sapiens	91.71	0.00e+00	1083.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	87.67	0.00e+00	1028.00
IUUC-Lpe-051254	Leersia perrieri	30.07	2.00e-36	146.00
IUUC-Loc-052610	Lepisosteus oculatus	73.95	0.00e+00	900.00
IUUC-Laf-053936	Loxodonta africana	91.72	0.00e+00	1087.00
IUUC-Mcc-055504	Macaca mulatta	90.44	0.00e+00	1115.00
IUUC-Meu-056516	Macropus eugenii	85.88	0.00e+00	984.00
IUUC-Mtr-058062	Medicago truncatula	32.34	3.00e-42	166.00
IUUC-Mga-059777	Meleagris gallopavo	85.33	0.00e+00	1031.00
IUUC-Mmr-061298	Microcebus murinus	95.43	0.00e+00	1114.00
IUUC-Mdo-062969	Monodelphis domestica	90.65	0.00e+00	1069.00
IUUC-Mmu-064076	Mus musculus	92.71	0.00e+00	1074.00
IUUC-Mac-065022	Musa acuminata	31.79	5.00e-40	157.00
IUUC-Mpu-066196	Mustela putorius furo	97.29	0.00e+00	1132.00
IUUC-Mlu-067651	Myotis lucifugus	92.05	0.00e+00	1088.00
IUUC-Nle-069853	Nomascus leucogenys	90.36	0.00e+00	1063.00
IUUC-Opr-070350	Ochotona princeps	92.20	6.00e-115	407.00
IUUC-Ont-072489	Oreochromis niloticus	72.30	0.00e+00	850.00
IUUC-Oan-072703	Ornithorhynchus anatinus	84.94	0.00e+00	958.00
IUUC-Ocu-074205	Oryctolagus cuniculus	91.71	0.00e+00	1097.00
IUUC-Oba-075619	Oryza barthii	30.18	7.00e-35	141.00
IUUC-Obr-076632	Oryza brachyantha	28.57	5.00e-36	145.00
IUUC-Ogl-077671	Oryza glaberrima	30.18	5.00e-35	142.00
IUUC-Ogu-078052	Oryza glumaepatula	30.18	6.00e-35	141.00
IUUC-Oin-079611	Oryza indica	29.82	3.00e-33	136.00
IUUC-Olo-080408	Oryza longistaminata	30.18	1.00e-34	140.00
IUUC-Ome-081560	Oryza meridionalis	30.18	5.00e-35	142.00
IUUC-Oni-082145	Oryza nivara	30.18	7.00e-35	141.00
IUUC-Opu-083918	Oryza punctata	29.82	2.00e-34	140.00
IUUC-Oru-084858	Oryza rufipogon	29.82	4.00e-33	135.00
IUUC-Osa-086277	Oryza sativa	29.82	3.00e-33	136.00
IUUC-Ola-086816	Oryzias latipes	68.95	7.00e-92	330.00
IUUC-Olu-087622	Ostreococcus lucimarinus	32.78	5.00e-43	168.00
IUUC-Oga-088765	Otolemur garnettii	88.83	0.00e+00	999.00
IUUC-Oar-090196	Ovis aries	91.58	0.00e+00	1031.00
IUUC-Ptr-091676	Pan troglodytes	91.88	0.00e+00	1085.00
IUUC-Pan-092068	Papio anubis	94.26	0.00e+00	1105.00
IUUC-Psi-093367	Pelodiscus sinensis	84.43	0.00e+00	995.00
IUUC-Ppa-095699	Physcomitrella patens	33.44	2.00e-39	157.00
IUUC-Pfo-096067	Poecilia formosa	71.55	0.00e+00	839.00
IUUC-Pab-098111	Pongo abelii	93.41	0.00e+00	1096.00
IUUC-Pop-099116	Populus trichocarpa	32.01	5.00e-42	165.00
IUUC-Pca-100680	Procavia capensis	82.35	0.00e+00	894.00
IUUC-Ppe-101790	Prunus persica	31.79	2.00e-43	169.00
IUUC-Pva-102871	Pteropus vampyrus	93.21	0.00e+00	1082.00
IUUC-Rno-106088	Rattus norvegicus	92.54	0.00e+00	1072.00
IUUC-Sha-106984	Sarcophilus harrisii	88.66	0.00e+00	1071.00
IUUC-Smo-109404	Selaginella moellendorffii	26.07	6.00e-42	165.00
IUUC-Sit-110828	Setaria italica	31.86	2.00e-39	156.00
IUUC-Sly-111009	Solanum lycopersicum	32.01	5.00e-45	175.00
IUUC-Stu-112370	Solanum tuberosum	32.01	1.00e-45	177.00
IUUC-Sar-113659	Sorex araneus	61.86	2.00e-92	331.00
IUUC-Sbi-114819	Sorghum bicolor	30.93	2.00e-37	149.00
IUUC-Ssc-116241	Sus scrofa	90.17	0.00e+00	1059.00
IUUC-Tgu-116576	Taeniopygia guttata	85.01	0.00e+00	1034.00
IUUC-Tru-118336	Takifugu rubripes	64.22	0.00e+00	706.00
IUUC-Tsy-119006	Tarsius syrichta	90.19	0.00e+00	1047.00
IUUC-Tni-120300	Tetraodon nigroviridis	72.28	0.00e+00	831.00
IUUC-Tca-121002	Theobroma cacao	32.19	2.00e-44	173.00
IUUC-Tae-124868	Triticum aestivum	29.76	2.00e-33	136.00
IUUC-Tur-126463	Triticum urartu	29.07	9.00e-33	135.00
IUUC-Tbe-127631	Tupaia belangeri	92.29	0.00e+00	909.00
IUUC-Ttr-129005	Tursiops truncatus	85.76	7.00e-165	573.00
IUUC-Vpa-130246	Vicugna pacos	86.86	0.00e+00	831.00
IUUC-Vvi-130878	Vitis vinifera	33.33	2.00e-42	167.00
IUUC-Xtr-132798	Xenopus tropicalis	73.27	0.00e+00	839.00
IUUC-Xma-133264	Xiphophorus maculatus	71.21	0.00e+00	837.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence