iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000001619.5	ENSGALT00000002475.5	ENSGALP00000002472.4
ENSGALG00000001619.5	ENSGALT00000059856.1	ENSGALP00000052554.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-33	112.2	422	461
UBD/Beta-Prp	3.00e-63	214.1	332	621

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           gH+++v + +f  ++ ++vsGs+D t+k+WDlr+ v++k+
   Q: 422  GHSGKVLSAKFllDNARIVSGSHDRTLKLWDLRSKVCIKT 461
           8***********64489********************985 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           +++++h++ +++v+fsp+++llatg++d+++k+w+v    +    slsg +a++t+++f++ g++l+ +s+D + ++w ++++   htl
   Q: 332  CVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVLGDRCepKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDNRLRHTL 420
           7899**********************************999999********************************************* PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
           +gh+ +vls +f  ++ ++vsGshdrt+++wdl+++ c++++++g +    c  + +++++++sG+ D+++r+Wd++t++++++l+   
   Q: 421  TGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRTESIVKELE--L 503
           ****************************************9999988....888888889*************************6..6 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
            ++++ l+++s+++el+++s+d  +k+ dl+ g + +t+ ++     +  ++v fsp++++++ gs+Dg +++W++ +g+l +tl++h+
   Q: 504  LGRITALDLNSERTELLTCSRDDLLKIIDLRVGAVKQTFSAQGfkcgSDWTRVVFSPDGNYVAAGSADGALYVWNVLTGKLERTLAKHH 592
           9********************************99888888887788777779************************************ PP
   S: 265  ssvisvavlsfgdnvlvlgsedskvniwk 293
           ss i   ++s+ + ++v++++ +k+ +w+
   Q: 593  SSPINAVAWSPAGAHVVSVDKGNKAVLWS 621
           *********************99999996 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MASGLHAAGF PPWKRHIAAE LRRRDRLQRQ AFEEIVAQYN KLLEKSDLHA VLADKLQAEK 60
YDMQSRHEIS PGHDGTWNDA QLQELAQLKI KHQEELTELH KKRGELAQSV IDLNNQMQQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTCGG GGCTGCACGC CGCCGGCTTC CCCCCCTGGA AGCGGCACAT CGCGGCAGAG 60
CTGCGGCGGA GGGACCGGCT GCAGCGGCAG GCCTTTGAGG AGATCGTCGC GCAGTGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR012284--6PGD_dom_3
IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0000045--P:autophagosome assembly
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	28.20	8.00e-33	134.00
IUUC-Aml-002242	Ailuropoda melanoleuca	81.32	0.00e+00	964.00
IUUC-Atr-003073	Amborella trichopoda	29.15	6.00e-28	118.00
IUUC-Apl-003384	Anas platyrhynchos	95.78	0.00e+00	1159.00
IUUC-Aca-004962	Anolis carolinensis	88.92	0.00e+00	1090.00
IUUC-Aly-005435	Arabidopsis lyrata	34.98	9.00e-47	181.00
IUUC-Ath-006948	Arabidopsis thaliana	34.98	2.00e-47	183.00
IUUC-Ame-010915	Astyanax mexicanus	81.04	9.00e-158	549.00
IUUC-Bta-012388	Bos taurus	88.28	0.00e+00	1105.00
IUUC-Bdi-014231	Brachypodium distachyon	28.53	4.00e-37	149.00
IUUC-Bol-016174	Brassica oleracea	35.97	4.00e-48	185.00
IUUC-Bra-017165	Brassica rapa	35.31	2.00e-47	183.00
IUUC-Cel-018131	Caenorhabditis elegans	37.89	4.00e-60	225.00
IUUC-Cja-018898	Callithrix jacchus	75.04	0.00e+00	885.00
IUUC-Cfa-020484	Canis familiaris	85.55	0.00e+00	1063.00
IUUC-Cpo-022156	Cavia porcellus	84.54	0.00e+00	1033.00
IUUC-Csa-024019	Chlorocebus sabaeus	82.18	0.00e+00	1009.00
IUUC-Cho-024311	Choloepus hoffmanni	73.56	0.00e+00	890.00
IUUC-Cin-025260	Ciona intestinalis	36.38	1.00e-100	360.00
IUUC-Csv-025836	Ciona savignyi	45.89	7.00e-51	192.00
IUUC-Dre-027702	Danio rerio	76.67	0.00e+00	921.00
IUUC-Dno-029728	Dasypus novemcinctus	86.22	0.00e+00	1100.00
IUUC-Dor-030587	Dipodomys ordii	76.49	2.00e-110	393.00
IUUC-Dme-031595	Drosophila melanogaster	39.58	8.00e-113	400.00
IUUC-Ete-032969	Echinops telfairi	69.69	0.00e+00	718.00
IUUC-Eca-034214	Equus caballus	86.61	0.00e+00	886.00
IUUC-Eeu-034537	Erinaceus europaeus	80.71	0.00e+00	840.00
IUUC-Fca-036005	Felis catus	88.25	0.00e+00	1029.00
IUUC-Fal-037593	Ficedula albicollis	97.69	0.00e+00	1129.00
IUUC-Gmo-039042	Gadus morhua	65.25	0.00e+00	692.00
IUUC-Gac-041351	Gasterosteus aculeatus	74.71	0.00e+00	929.00
IUUC-Gma-043265	Glycine max	28.44	1.00e-47	184.00
IUUC-Ggo-045427	Gorilla gorilla	85.74	0.00e+00	1056.00
IUUC-Hsa-046632	Homo sapiens	84.11	0.00e+00	1044.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	81.09	0.00e+00	994.00
IUUC-Lch-049439	Latimeria chalumnae	49.76	4.00e-146	511.00
IUUC-Lpe-051254	Leersia perrieri	29.80	5.00e-38	152.00
IUUC-Loc-052610	Lepisosteus oculatus	78.14	0.00e+00	965.00
IUUC-Laf-053936	Loxodonta africana	84.62	0.00e+00	1051.00
IUUC-Mcc-055504	Macaca mulatta	83.20	0.00e+00	1071.00
IUUC-Meu-056516	Macropus eugenii	83.81	0.00e+00	1013.00
IUUC-Mtr-058062	Medicago truncatula	32.01	1.00e-43	171.00
IUUC-Mga-059777	Meleagris gallopavo	93.67	0.00e+00	1155.00
IUUC-Mmr-061298	Microcebus murinus	88.28	0.00e+00	1078.00
IUUC-Mdo-062969	Monodelphis domestica	88.78	0.00e+00	1098.00
IUUC-Mmu-064076	Mus musculus	86.01	0.00e+00	1042.00
IUUC-Mac-065161	Musa acuminata	27.27	6.00e-41	161.00
IUUC-Mpu-066196	Mustela putorius furo	88.28	0.00e+00	1079.00
IUUC-Mlu-067651	Myotis lucifugus	84.46	0.00e+00	1049.00
IUUC-Nle-069853	Nomascus leucogenys	83.15	0.00e+00	1029.00
IUUC-Opr-070350	Ochotona princeps	87.32	3.00e-110	392.00
IUUC-Ont-072489	Oreochromis niloticus	75.33	0.00e+00	919.00
IUUC-Oan-072703	Ornithorhynchus anatinus	83.47	0.00e+00	992.00
IUUC-Ocu-074205	Oryctolagus cuniculus	84.75	0.00e+00	1057.00
IUUC-Oba-075619	Oryza barthii	30.18	2.00e-36	146.00
IUUC-Obr-076632	Oryza brachyantha	29.64	3.00e-38	152.00
IUUC-Ogl-077671	Oryza glaberrima	30.18	2.00e-36	146.00
IUUC-Ogu-078052	Oryza glumaepatula	30.18	2.00e-36	146.00
IUUC-Oin-079611	Oryza indica	29.82	1.00e-34	140.00
IUUC-Olo-080408	Oryza longistaminata	30.18	4.00e-36	145.00
IUUC-Ome-081560	Oryza meridionalis	30.18	2.00e-36	146.00
IUUC-Oni-082145	Oryza nivara	30.18	2.00e-36	146.00
IUUC-Opu-083918	Oryza punctata	29.82	7.00e-36	145.00
IUUC-Oru-084858	Oryza rufipogon	29.82	2.00e-34	140.00
IUUC-Osa-086277	Oryza sativa	29.82	1.00e-34	140.00
IUUC-Ola-086816	Oryzias latipes	72.06	5.00e-104	370.00
IUUC-Olu-087622	Ostreococcus lucimarinus	35.00	1.00e-43	170.00
IUUC-Oga-088765	Otolemur garnettii	80.93	0.00e+00	961.00
IUUC-Oar-090196	Ovis aries	86.37	0.00e+00	971.00
IUUC-Ptr-091676	Pan troglodytes	84.27	0.00e+00	1046.00
IUUC-Pan-092068	Papio anubis	86.54	0.00e+00	1064.00
IUUC-Psi-093367	Pelodiscus sinensis	90.37	0.00e+00	1094.00
IUUC-Ppa-095699	Physcomitrella patens	29.65	3.00e-42	166.00
IUUC-Pfo-096067	Poecilia formosa	73.04	0.00e+00	889.00
IUUC-Pab-098111	Pongo abelii	85.74	0.00e+00	1057.00
IUUC-Pop-099116	Populus trichocarpa	33.04	1.00e-45	177.00
IUUC-Pca-100680	Procavia capensis	77.23	0.00e+00	880.00
IUUC-Ppe-101790	Prunus persica	31.79	2.00e-44	173.00
IUUC-Pva-102871	Pteropus vampyrus	85.67	0.00e+00	1006.00
IUUC-Rno-106088	Rattus norvegicus	85.37	0.00e+00	1033.00
IUUC-Sha-106984	Sarcophilus harrisii	86.00	0.00e+00	1056.00
IUUC-Smo-109404	Selaginella moellendorffii	33.11	8.00e-43	167.00
IUUC-Sit-110828	Setaria italica	31.51	9.00e-40	157.00
IUUC-Sly-111009	Solanum lycopersicum	31.04	6.00e-46	178.00
IUUC-Stu-112370	Solanum tuberosum	31.56	6.00e-47	181.00
IUUC-Sar-113659	Sorex araneus	57.37	1.00e-83	302.00
IUUC-Sbi-114819	Sorghum bicolor	30.94	2.00e-40	159.00
IUUC-Ssc-116241	Sus scrofa	84.15	0.00e+00	1031.00
IUUC-Tgu-116576	Taeniopygia guttata	95.02	0.00e+00	1184.00
IUUC-Tru-118336	Takifugu rubripes	68.30	0.00e+00	779.00
IUUC-Tsy-119006	Tarsius syrichta	84.27	0.00e+00	1018.00
IUUC-Tni-120300	Tetraodon nigroviridis	74.55	0.00e+00	890.00
IUUC-Tca-121002	Theobroma cacao	35.14	4.00e-49	189.00
IUUC-Tae-124868	Triticum aestivum	28.85	7.00e-34	138.00
IUUC-Tur-126463	Triticum urartu	28.20	3.00e-33	136.00
IUUC-Tbe-127631	Tupaia belangeri	85.77	0.00e+00	849.00
IUUC-Ttr-129005	Tursiops truncatus	78.33	2.00e-153	535.00
IUUC-Vpa-130246	Vicugna pacos	79.70	0.00e+00	802.00
IUUC-Vvi-130878	Vitis vinifera	34.60	1.00e-45	177.00
IUUC-Xtr-132798	Xenopus tropicalis	72.13	0.00e+00	868.00
IUUC-Xma-133264	Xiphophorus maculatus	72.71	0.00e+00	884.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence