iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045318

Ensembl Protein ID

ENSGGOP00000024163.1

UniProt Accession

G3S7V3; G3S7V3_GORGO

Protein Name

Uncharacterized protein

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000016335.2	ENSGGOT00000032102.1	ENSGGOP00000024163.1
ENSGGOG00000016335.2	ENSGGOT00000016397.2	ENSGGOP00000015943.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.40e-41	140.6	66	137

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 3    eeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           eeyrlll++lq+++++++++td+++ +lse+l+++e+e+il++++tkg+m++ae+L+++L  ++ke+W+++++
   Q: 66   EEYRLLLKRLQPEFKTRIIPTDIIS-DLSECLINQECEEILQICSTKGMMAGAEKLVECLlrSDKENWPKTLK 137
           9************************.********************************************985 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

EEVQYIQAEK NNKGPMEAAT LFLKFLLELQ EEGWFRGFLD ALDHAGYSGL YEAIESWDFK 60
KIEKLEEYRL LLKRLQPEFK TRIIPTDIIS DLSECLINQE CEEILQICST KGMMAGAEKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCTCGG AGCAGCGGCG CAGCCTGCAA GCCTTCCAGG ATTATATCCG GAAGACCCTG 60
GACCCTACCT ACATCCTGAG CTACATGGCC CCCTGGTTTA GGGAGGGTGA GTGTCTCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011545--DEAD/DEAH_box_helicase_dom
IPR011029--DEATH-like_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00270--DEAD
PF00271--Helicase_C
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	77.70	0.00e+00	1381.00
IUUC-Apl-003966	Anas platyrhynchos	53.56	0.00e+00	915.00
IUUC-Aca-004499	Anolis carolinensis	45.46	0.00e+00	746.00
IUUC-Ame-011950	Astyanax mexicanus	44.21	0.00e+00	679.00
IUUC-Bta-012489	Bos taurus	78.24	0.00e+00	1350.00
IUUC-Cel-018230	Caenorhabditis elegans	29.21	2.00e-71	264.00
IUUC-Cja-018716	Callithrix jacchus	90.92	0.00e+00	1599.00
IUUC-Cfa-020269	Canis familiaris	79.62	0.00e+00	1426.00
IUUC-Cpo-022507	Cavia porcellus	74.00	0.00e+00	1316.00
IUUC-Csa-024209	Chlorocebus sabaeus	92.49	0.00e+00	1632.00
IUUC-Cho-025104	Choloepus hoffmanni	71.48	0.00e+00	1132.00
IUUC-Cin-025792	Ciona intestinalis	31.47	2.00e-79	290.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	25.42	5.00e-23	103.00
IUUC-Dno-028954	Dasypus novemcinctus	77.08	0.00e+00	1329.00
IUUC-Eca-034039	Equus caballus	79.55	0.00e+00	1413.00
IUUC-Eeu-035009	Erinaceus europaeus	70.02	0.00e+00	930.00
IUUC-Fca-036169	Felis catus	80.34	0.00e+00	1444.00
IUUC-Fal-037579	Ficedula albicollis	53.42	0.00e+00	927.00
IUUC-Fso-038398	Fusarium solani	27.29	5.00e-25	110.00
IUUC-Hsa-046671	Homo sapiens	95.85	0.00e+00	1657.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	76.80	0.00e+00	1333.00
IUUC-Lch-050461	Latimeria chalumnae	51.58	0.00e+00	880.00
IUUC-Loc-052582	Lepisosteus oculatus	49.60	0.00e+00	821.00
IUUC-Laf-054324	Loxodonta africana	77.20	0.00e+00	1329.00
IUUC-Mcc-055390	Macaca mulatta	91.70	0.00e+00	1618.00
IUUC-Meu-056365	Macropus eugenii	53.39	3.00e-170	592.00
IUUC-Mvi-060497	Microbotryum violaceum	24.23	2.00e-23	105.00
IUUC-Mmr-061407	Microcebus murinus	83.63	0.00e+00	1502.00
IUUC-Mmu-063939	Mus musculus	75.31	0.00e+00	1323.00
IUUC-Mpu-066226	Mustela putorius furo	77.57	0.00e+00	1373.00
IUUC-Mlu-068092	Myotis lucifugus	78.89	0.00e+00	1363.00
IUUC-Nfi-068405	Neosartorya fischeri	25.04	1.00e-26	115.00
IUUC-Opr-070246	Ochotona princeps	64.41	0.00e+00	637.00
IUUC-Oan-072742	Ornithorhynchus anatinus	60.51	0.00e+00	967.00
IUUC-Ocu-073959	Oryctolagus cuniculus	74.58	0.00e+00	1345.00
IUUC-Oga-089173	Otolemur garnettii	82.27	0.00e+00	1445.00
IUUC-Oar-089369	Ovis aries	77.15	0.00e+00	1303.00
IUUC-Ptr-091032	Pan troglodytes	95.85	0.00e+00	1657.00
IUUC-Pan-092383	Papio anubis	92.05	0.00e+00	1615.00
IUUC-Psi-093432	Pelodiscus sinensis	56.16	0.00e+00	988.00
IUUC-Pma-094367	Petromyzon marinus	42.83	3.00e-118	419.00
IUUC-Pab-098416	Pongo abelii	94.75	0.00e+00	1605.00
IUUC-Pca-101006	Procavia capensis	77.47	0.00e+00	635.00
IUUC-Pva-102966	Pteropus vampyrus	80.56	0.00e+00	1420.00
IUUC-Pgr-103529	Puccinia graminis	27.41	8.00e-29	123.00
IUUC-Rno-105059	Rattus norvegicus	73.66	0.00e+00	805.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	27.55	9.00e-05	43.90
IUUC-Sar-113202	Sorex araneus	66.89	0.00e+00	952.00
IUUC-Ssc-116120	Sus scrofa	75.92	0.00e+00	1318.00
IUUC-Tgu-117314	Taeniopygia guttata	52.75	0.00e+00	909.00
IUUC-Tsy-119453	Tarsius syrichta	85.03	0.00e+00	905.00
IUUC-Tre-122194	Trichoderma reesei	26.31	3.00e-20	94.70
IUUC-Ttr-128421	Tursiops truncatus	75.44	0.00e+00	1163.00
IUUC-Vpa-130602	Vicugna pacos	75.95	0.00e+00	1343.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence