iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132507

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Suppressor of cytokine signaling 7

Genbank Nucleotide ID

AAMC01100255

Gene Name

socs7; SOCS7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000034343.1	ENSXETT00000065432.1	ENSXETP00000060856.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	4.20e-15	55.5	397	444

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
           +++ +++s++ SLqhLCR++Ir++++++++   ++LPLPk L++YL+++ y
   Q: 397  LYPVSRFSNVKSLQHLCRFRIRQLVRIDHI---PELPLPKPLISYLRKFYY 444
           567899*********************998...**************9976 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MVFRNMLRGE EEGGEAAPEP EALVEALPAE GSPQSAELCN RHRKAAQPGL GLELQLGALG 60
LRGAGCPCEE TSDALLVLEA PEARRLEEQE EGEAAGQAPS RRAQNRKASL RNRLSRIFRT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCTATCGG GTGCTGAGCC GGTTGCTAGG CTGCGCTCCT GAGGCGGAGG ACGCTGCAAG 60
ACCCCGGCTA ATGGTGTTCC GGAACATGCT GAGAGGAGAG GAGGAGGGGG GAGAGGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028423--SOCS7
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0016567--P:protein ubiquitination

KEGG

xtr:100158657

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001668	Ailuropoda melanoleuca	80.37	3.00e-149	521.00
IUUC-Apl-003277	Anas platyrhynchos	91.78	3.00e-72	263.00
IUUC-Aca-004639	Anolis carolinensis	92.39	2.00e-102	364.00
IUUC-Ame-011301	Astyanax mexicanus	65.78	7.00e-123	433.00
IUUC-Bta-013483	Bos taurus	82.34	9.00e-149	520.00
IUUC-Cel-018643	Caenorhabditis elegans	30.30	7.00e-12	63.50
IUUC-Cja-019765	Callithrix jacchus	86.83	3.00e-141	493.00
IUUC-Cfa-020109	Canis familiaris	81.43	4.00e-153	534.00
IUUC-Cpo-021555	Cavia porcellus	80.64	1.00e-149	522.00
IUUC-Csa-023580	Chlorocebus sabaeus	80.90	1.00e-149	522.00
IUUC-Cho-024431	Choloepus hoffmanni	90.55	7.00e-66	243.00
IUUC-Dre-028183	Danio rerio	69.13	6.00e-133	468.00
IUUC-Dno-028858	Dasypus novemcinctus	79.95	1.00e-148	520.00
IUUC-Dor-031071	Dipodomys ordii	66.67	7.00e-93	333.00
IUUC-Dme-031876	Drosophila melanogaster	47.40	6.00e-42	166.00
IUUC-Ete-032928	Echinops telfairi	61.61	2.00e-84	305.00
IUUC-Eca-033250	Equus caballus	76.96	1.00e-145	509.00
IUUC-Eeu-034946	Erinaceus europaeus	84.52	1.00e-37	150.00
IUUC-Fca-036589	Felis catus	81.17	7.00e-151	526.00
IUUC-Fal-037316	Ficedula albicollis	88.61	4.00e-106	376.00
IUUC-Gmo-038552	Gadus morhua	93.20	9.00e-54	201.00
IUUC-Gga-041248	Gallus gallus	92.43	4.00e-103	366.00
IUUC-Gac-041469	Gasterosteus aculeatus	85.59	2.00e-56	210.00
IUUC-Ggo-045282	Gorilla gorilla	86.48	2.00e-140	491.00
IUUC-Hsa-045926	Homo sapiens	80.64	4.00e-149	521.00
IUUC-Itr-048411	Ictidomys tridecemlineatus	80.27	7.00e-109	387.00
IUUC-Lch-049768	Latimeria chalumnae	77.49	3.00e-136	478.00
IUUC-Loc-051949	Lepisosteus oculatus	70.00	9.00e-122	431.00
IUUC-Laf-053410	Loxodonta africana	81.17	4.00e-152	531.00
IUUC-Mcc-054605	Macaca mulatta	72.10	2.00e-142	498.00
IUUC-Meu-056773	Macropus eugenii	69.50	5.00e-89	320.00
IUUC-Mmr-060927	Microcebus murinus	81.17	2.00e-150	525.00
IUUC-Mdo-061892	Monodelphis domestica	80.58	4.00e-144	504.00
IUUC-Mmu-064246	Mus musculus	80.64	5.00e-149	521.00
IUUC-Mpu-065995	Mustela putorius furo	81.17	7.00e-151	526.00
IUUC-Mlu-067526	Myotis lucifugus	80.64	2.00e-150	525.00
IUUC-Nle-069317	Nomascus leucogenys	81.55	1.00e-135	476.00
IUUC-Ont-072275	Oreochromis niloticus	76.77	1.00e-113	402.00
IUUC-Oan-073703	Ornithorhynchus anatinus	80.49	2.00e-36	143.00
IUUC-Ocu-074577	Oryctolagus cuniculus	80.64	5.00e-151	527.00
IUUC-Oga-088426	Otolemur garnettii	81.65	4.00e-151	528.00
IUUC-Oar-089407	Ovis aries	82.34	1.00e-149	522.00
IUUC-Ptr-091327	Pan troglodytes	80.64	2.00e-150	525.00
IUUC-Pan-092064	Papio anubis	81.07	1.00e-150	526.00
IUUC-Psi-093834	Pelodiscus sinensis	86.52	8.00e-141	492.00
IUUC-Pfo-097100	Poecilia formosa	57.49	2.00e-111	396.00
IUUC-Pab-097695	Pongo abelii	80.80	1.00e-148	519.00
IUUC-Pca-100569	Procavia capensis	79.03	9.00e-144	503.00
IUUC-Pva-102784	Pteropus vampyrus	80.59	9.00e-151	526.00
IUUC-Ptt-103775	Puccinia triticina	38.46	6.90e-01	29.30
IUUC-Rno-105485	Rattus norvegicus	80.64	6.00e-149	520.00
IUUC-Sha-106720	Sarcophilus harrisii	81.43	6.00e-146	510.00
IUUC-Smo-109349	Selaginella moellendorffii	42.42	9.60e-01	28.90
IUUC-Sar-112975	Sorex araneus	73.58	6.00e-108	383.00
IUUC-Ssc-116369	Sus scrofa	82.34	9.00e-149	520.00
IUUC-Tgu-116867	Taeniopygia guttata	82.45	2.00e-119	421.00
IUUC-Tru-117562	Takifugu rubripes	83.02	1.00e-100	359.00
IUUC-Tsy-118999	Tarsius syrichta	81.45	2.00e-125	441.00
IUUC-Tni-120793	Tetraodon nigroviridis	63.82	1.00e-121	429.00
IUUC-Tbe-127671	Tupaia belangeri	92.96	7.00e-112	397.00
IUUC-Ttr-128491	Tursiops truncatus	70.87	2.00e-102	365.00
IUUC-Vpa-130104	Vicugna pacos	77.87	5.00e-140	491.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence