iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067460

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02023099

Gene Name

WDR59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000000584.2	ENSMLUT00000000597.2	ENSMLUP00000000541.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.80e-19	67.3	190	224

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           H +++++l++ +d  ++l+++s D+++k WD+r+ 
   Q: 190  HLSKIHGLDWhPDseHILATSSQDNSVKFWDYRQP 224
           99*********6665778*************9876 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MAARWSSENV VVEFRDSQAT AMSVDCLGQH AVLSGRRFLY IVNLDAPFEG HRKISRQSKW 60
DIGTVQWNPH DSFAHYFAAS SNQRVDLYKW KDGCGEVGTT LQGHTRVISD LDWAVFEPDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCAC GATGGAGCAG CGAGAACGTG GTGGTGGAGT TCCGCGACTC CCAGGTGAGC 60
CGGGGGCCAA ATGGAGCCTT CTGGGCATGC GCTCTCTCGG TTCCCCTCCC CCACGCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50908--RWD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00591--RWD
SM00320--WD40

Gene Ontology

GO:0061700--C:GATOR2 complex
GO:0034198--P:cellular response to amino acid starvation
GO:0032008--P:positive regulation of TOR signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002149	Ailuropoda melanoleuca	95.27	0.00e+00	1914.00
IUUC-Apl-004021	Anas platyrhynchos	86.82	0.00e+00	1672.00
IUUC-Aca-004977	Anolis carolinensis	83.04	0.00e+00	1697.00
IUUC-Ago-007961	Ashbya gossypii	29.66	4.00e-57	216.00
IUUC-Acl-008161	Aspergillus clavatus	28.62	3.00e-56	214.00
IUUC-Afl-008686	Aspergillus flavus	28.49	9.00e-59	222.00
IUUC-Afu-008932	Aspergillus fumigatus	28.14	3.00e-55	210.00
IUUC-Ani-009493	Aspergillus nidulans	34.65	3.00e-54	207.00
IUUC-Ang-009876	Aspergillus niger	28.95	4.00e-59	223.00
IUUC-Aor-009926	Aspergillus oryzae	28.49	1.00e-58	222.00
IUUC-Ate-010274	Aspergillus terreus	33.54	7.00e-51	196.00
IUUC-Ame-011297	Astyanax mexicanus	69.01	0.00e+00	1401.00
IUUC-Bgr-012173	Blumeria graminis	31.79	3.00e-44	174.00
IUUC-Bta-013261	Bos taurus	95.57	0.00e+00	1925.00
IUUC-Bci-013971	Botrytis cinerea	32.82	3.00e-46	181.00
IUUC-Cja-019167	Callithrix jacchus	94.16	0.00e+00	1900.00
IUUC-Cfa-020287	Canis familiaris	95.07	0.00e+00	1908.00
IUUC-Cpo-022510	Cavia porcellus	92.25	0.00e+00	1804.00
IUUC-Csa-023474	Chlorocebus sabaeus	93.58	0.00e+00	1930.00
IUUC-Cho-024634	Choloepus hoffmanni	92.65	0.00e+00	786.00
IUUC-Cin-025642	Ciona intestinalis	32.60	9.00e-129	454.00
IUUC-Csv-025848	Ciona savignyi	45.15	6.00e-55	206.00
IUUC-Cgl-026531	Colletotrichum gloeosporioides	32.48	2.00e-44	175.00
IUUC-Cne-027088	Cryptococcus neoformans	25.00	2.00e-44	174.00
IUUC-Dre-028753	Danio rerio	70.27	0.00e+00	1389.00
IUUC-Dno-029733	Dasypus novemcinctus	92.85	0.00e+00	1858.00
IUUC-Dor-030781	Dipodomys ordii	93.60	0.00e+00	974.00
IUUC-Dme-031803	Drosophila melanogaster	33.66	2.00e-146	513.00
IUUC-Ete-032622	Echinops telfairi	85.81	0.00e+00	1689.00
IUUC-Eca-033344	Equus caballus	95.88	0.00e+00	1914.00
IUUC-Eeu-034523	Erinaceus europaeus	85.66	0.00e+00	1655.00
IUUC-Fca-035650	Felis catus	95.88	0.00e+00	1929.00
IUUC-Fal-037404	Ficedula albicollis	86.49	0.00e+00	1708.00
IUUC-Fox-037955	Fusarium oxysporum	33.45	8.00e-43	169.00
IUUC-Fso-038289	Fusarium solani	32.92	8.00e-47	183.00
IUUC-Gmo-038547	Gadus morhua	66.34	0.00e+00	1375.00
IUUC-Ggr-039858	Gaeumannomyces graminis	35.74	8.00e-43	169.00
IUUC-Gga-041030	Gallus gallus	86.92	0.00e+00	1722.00
IUUC-Gac-042581	Gasterosteus aculeatus	69.69	0.00e+00	1431.00
IUUC-Ggo-044641	Gorilla gorilla	95.27	0.00e+00	1925.00
IUUC-Hsa-046134	Homo sapiens	95.57	0.00e+00	1929.00
IUUC-Itr-048551	Ictidomys tridecemlineatus	97.28	0.00e+00	755.00
IUUC-Kpa-049091	Komagataella pastoris	32.34	2.00e-45	178.00
IUUC-Lch-050288	Latimeria chalumnae	73.60	0.00e+00	1457.00
IUUC-Loc-052802	Lepisosteus oculatus	72.47	0.00e+00	1484.00
IUUC-Lma-053296	Leptosphaeria maculans	32.92	1.00e-48	189.00
IUUC-Laf-053997	Loxodonta africana	93.48	0.00e+00	1937.00
IUUC-Mcc-055855	Macaca mulatta	95.37	0.00e+00	1910.00
IUUC-Meu-056898	Macropus eugenii	90.38	0.00e+00	721.00
IUUC-Mor-056913	Magnaporthe oryzae	34.63	4.00e-42	167.00
IUUC-Mpo-057612	Magnaporthe poae	36.10	2.00e-43	171.00
IUUC-Mla-059097	Melampsora laricipopulina	30.67	5.00e-47	183.00
IUUC-Mga-059218	Meleagris gallopavo	86.80	0.00e+00	1686.00
IUUC-Mvi-060251	Microbotryum violaceum	31.29	2.00e-46	181.00
IUUC-Mmr-061093	Microcebus murinus	92.45	0.00e+00	1848.00
IUUC-Mdo-062757	Monodelphis domestica	93.29	0.00e+00	1827.00
IUUC-Mmu-063839	Mus musculus	92.60	0.00e+00	1919.00
IUUC-Mpu-065977	Mustela putorius furo	95.88	0.00e+00	1930.00
IUUC-Nfi-068250	Neosartorya fischeri	34.88	2.00e-52	201.00
IUUC-Ncr-068710	Neurospora crassa	32.15	4.00e-45	177.00
IUUC-Nle-070011	Nomascus leucogenys	95.37	0.00e+00	1921.00
IUUC-Opr-070731	Ochotona princeps	88.23	0.00e+00	1734.00
IUUC-Ont-072165	Oreochromis niloticus	71.00	0.00e+00	1431.00
IUUC-Oan-072887	Ornithorhynchus anatinus	89.96	0.00e+00	1842.00
IUUC-Ocu-073926	Oryctolagus cuniculus	92.85	0.00e+00	1752.00
IUUC-Ola-087111	Oryzias latipes	66.14	0.00e+00	1348.00
IUUC-Oga-088850	Otolemur garnettii	95.27	0.00e+00	1917.00
IUUC-Oar-090291	Ovis aries	95.47	0.00e+00	1925.00
IUUC-Ptr-091044	Pan troglodytes	95.17	0.00e+00	1914.00
IUUC-Pan-092374	Papio anubis	93.39	0.00e+00	1925.00
IUUC-Psi-093170	Pelodiscus sinensis	55.56	0.00e+00	963.00
IUUC-Pma-094544	Petromyzon marinus	67.34	2.00e-170	591.00
IUUC-Pno-095068	Phaeosphaeria nodorum	30.56	2.00e-44	174.00
IUUC-Pfo-096480	Poecilia formosa	66.80	0.00e+00	1324.00
IUUC-Pab-098134	Pongo abelii	94.14	0.00e+00	1880.00
IUUC-Pca-100763	Procavia capensis	75.29	0.00e+00	997.00
IUUC-Pva-102544	Pteropus vampyrus	95.67	0.00e+00	1935.00
IUUC-Pgr-103257	Puccinia graminis	32.02	1.00e-49	192.00
IUUC-Ptt-103942	Puccinia triticina	31.23	1.00e-45	178.00
IUUC-Pte-104065	Pyrenophora teres	32.20	5.00e-46	180.00
IUUC-Rno-105468	Rattus norvegicus	90.76	0.00e+00	1746.00
IUUC-Sce-106356	Saccharomyces cerevisiae	28.32	3.00e-57	217.00
IUUC-Sha-106662	Sarcophilus harrisii	93.16	0.00e+00	1838.00
IUUC-Sja-107973	Schizosaccharomyces japonicus	27.08	2.00e-69	257.00
IUUC-Spo-108265	Schizosaccharomyces pombe	33.44	7.00e-49	189.00
IUUC-Ssl-108662	Sclerotinia sclerotiorum	33.14	9.00e-46	179.00
IUUC-Sar-113525	Sorex araneus	92.12	0.00e+00	1080.00
IUUC-Sre-115163	Sporisorium reilianum	37.05	2.00e-40	161.00
IUUC-Ssc-115381	Sus scrofa	93.43	0.00e+00	1040.00
IUUC-Tgu-116525	Taeniopygia guttata	83.22	0.00e+00	1643.00
IUUC-Tru-118432	Takifugu rubripes	67.94	0.00e+00	1400.00
IUUC-Tsy-119306	Tarsius syrichta	78.57	0.00e+00	1236.00
IUUC-Tni-120757	Tetraodon nigroviridis	67.71	0.00e+00	1361.00
IUUC-Tre-122187	Trichoderma reesei	35.03	4.00e-48	187.00
IUUC-Tvi-122367	Trichoderma virens	35.35	1.00e-47	186.00
IUUC-Tme-126986	Tuber melanosporum	24.89	2.00e-60	228.00
IUUC-Tbe-127800	Tupaia belangeri	80.11	0.00e+00	1365.00
IUUC-Ttr-129154	Tursiops truncatus	87.30	0.00e+00	1697.00
IUUC-Uma-129366	Ustilago maydis	35.97	2.00e-39	158.00
IUUC-Vda-129827	Verticillium dahliae	33.54	2.00e-47	184.00
IUUC-Vpa-130493	Vicugna pacos	95.49	0.00e+00	1871.00
IUUC-Xtr-131941	Xenopus tropicalis	79.90	0.00e+00	1592.00
IUUC-Xma-133903	Xiphophorus maculatus	68.01	0.00e+00	1394.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence